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Valance 500 Solution is used to treat epilepsy (seizures/fits). It can be used alone or in combination with other medications to treat complex partial seizures that occur alone or alongside other types of seizures. It contains Divalproex sodium, which decreases the brain's excessive and abnormal nerve activity, thereby helping to control seizures. In some cases, it may cause common side effects such as drowsiness, dizziness, and nausea. Before taking this medicine, you should inform your doctor if you are allergic to any of its components, if you are pregnant/breastfeeding, and about all the medications you are taking, as well as any pre-existing medical conditions.

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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Valance 500 Solution

Valance 500 Solution is an oral liquid medicine prescribed to help manage and control brain-related conditions, including epilepsy and certain types of seizures. It is also used to stabilise moods during manic phases of bipolar disorder and to prevent severe migraine headaches from occurring. By helping to calm hyperactive signals in the brain, this medicine supports smoother daily functioning and improves long-term symptom management.

For this medicine to work effectively, you must take it consistently every day at the exact times prescribed by your doctor. It can be taken with or without food, though taking your dose with meals can help prevent stomach upset. Making supportive lifestyle adjustments, such as maintaining a consistent sleep schedule and keeping a daily symptom log, can greatly enhance your treatment outcomes.

While taking Valance 500 Solution , you may experience common side effects like mild sleepiness, nausea, or dizziness. However, you should contact your doctor immediately if you experience serious symptoms such as severe stomach pain spreading to your back, dark urine, or yellowing of your skin or eyes. These can be early signs of rare but serious complications involving your pancreas or liver.

Before starting this medicine, tell your doctor if you have a history of liver problems, kidney disease, or certain metabolic disorders. Do not take this if you have active liver disease, a family history of severe liver dysfunction, or urea cycle disorders. It is also highly critical that women who are pregnant or planning to become pregnant avoid taking this medicine for migraine prevention due to severe risks to the unborn baby.

This medicine can interact with alcohol, tobacco, and other prescription medications, which may increase drowsiness or alter how well your body processes the treatment. If you are pregnant, breastfeeding, or an older adult, it is vital to consult your doctor or pharmacist to discuss safe usage, as special monitoring or alternative options may be required.

Uses of Valance 500 Solution

Valance 500 Solution is used in the treatment of epilepsy (seizures). The detailed uses of Valance 500 Solution are as follows:

  • Epilepsy and Seizures: Valance 500 Solution helps control various types of seizures by stabilising abnormal electrical activity in the brain, which reduces the frequency and severity of sudden episodes.
  • Bipolar Disorder (Manic Episodes): It treats periods of high energy, excitement, or irritability associated with manic phases, helping to restore a more balanced emotional state.
  • Migraine Prevention: It helps reduce the frequency of severe migraine headaches when taken daily as a long-term preventive measure.

Key Benefits

Valance 500 Solution may provide therapeutic benefits in certain neurological conditions when used as prescribed by a doctor.
Benefits may include:

  • Valance 500 Solution may help reduce the frequency of seizures in people for whom it has been prescribed, supporting better control of seizure-related symptoms.
  • When prescribed for bipolar disorder, Valance 500 Solution may help manage episodes of mood changes and support greater emotional stability.
  • In patients prescribed this medicine for migraine prevention, Valance 500 Solution may help reduce the frequency of migraine episodes and the number of days affected by migraine symptoms.
  • As an oral liquid formulation, Valance 500 Solution may be easier to administer to children, older adults, or other patients who have difficulty swallowing tablets or capsules.
Side effects of Valance 500 Oral Solution 200 ml
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Eat a balanced diet containing enough proteins, fibre, healthy fats, vegetables and fruits.
  • Get quality sleep for about 7-9 hours.
  • Try to manage stress with meditation or yoga.
  • Drink enough water.
  • Exercise regularly as it helps regulate appetite.

Directions for Use

  • Valance 500 Solution can be taken with or without food, or as advised by the doctor.
  • Shake the bottle well before each use.
  • Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided with the pack.
  • Replace the bottle cap tightly after each use.
  • Avoid using regular household spoons, as they may not accurately measure the dose.
  • Your doctor may adjust the dose and frequency of this medication based on your medical condition.

How Valance 500 Solution Works

Valance 500 Solution works directly in the central nervous system to calm overactive nerve signals. In conditions like epilepsy, bipolar disorder, and migraines, certain nerve pathways in the brain can become overly excited, leading to seizures, extreme mood shifts, or headache triggers. This medicine helps by increasing the amount of a natural chemical messenger in the brain called gamma-aminobutyric acid (GABA). GABA acts as a natural brake system, blocking extra electrical signals and slowing down hyperactive nerve pathways. By boosting these calming signals, the medicine effectively prevents seizure activity, balances mood pathways, and reduces the brain excitability that triggers migraine attacks.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Valance 500 Solution , as it may cause increased drowsiness and dizziness.

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Pregnancy

Unsafe

Valance 500 Solution belongs to pregnancy category D. Avoid taking Valance 500 Solution if you are pregnant, as it could lead to serious birth defects. Consult your doctor for further advice.

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Breast Feeding

Caution

Valance 500 Solution may pass into breastmilk. Consult your doctor before taking Valance 500 Solution if you are breastfeeding.

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Driving

Unsafe

Valance 500 Solution causes drowsiness and dizziness. Therefore, do not drive or operate machinery until you are mentally alert.

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Liver

Unsafe

Valance 500 Solution should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns regarding this. Dose adjustment may be needed in patients with kidney impairment.

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Children

Caution

Valance 500 Solution should be given to children only if prescribed by a doctor.

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Heart

Caution

Please inform your doctor if you have heart problems before taking Valance 500 Solution , as there is limited information available on its safety in such cases.

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Geriatrics

Caution

Valance 500 Solution can be taken if you're geriatric, but it requires careful monitoring and medical supervision.

What if I have taken an overdose of Valance 500 Solution

If you or someone else takes too much of this medicine, seek immediate medical attention or contact your local poison control centre. Symptoms of a severe overdose may include extreme sleepiness, shallow breathing, weak muscles, or loss of consciousness.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink enough fluids throughout the day, unless your doctor has advised you to restrict fluids. Maintaining adequate hydration can support overall health during treatment.
  • Track your symptoms: Keep a seizure, mood, or migraine diary, as appropriate for your condition. Recording symptoms, triggers, and changes over time can help your doctor assess your response to treatment.
  • Limit or avoid alcohol: Alcohol may increase drowsiness or dizziness with some medicines and can affect seizure control or migraine symptoms in some people. Ask your doctor whether alcohol is safe for you while taking Valance 500 Solution .
  • Maintain a balanced diet: Follow a varied, nutritious diet and monitor any significant changes in appetite or weight. Inform your doctor if you notice persistent or unexpected weight changes during treatment.
  • Maintain a regular sleep schedule: Aim for consistent sleep and wake times, as inadequate or irregular sleep may trigger seizures or migraine episodes in some people.
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Have a query?

How Soon It Starts Working

  • The time required for Valance 500 Solution to start to work: Valance 500 Solution ideally shows its action within 15 minutes to 2 hours after administration.
  • The time for which the effects of Valance 500 Solution last: The effect of Valance 500 Solution lasts for 4 to 6 hours.

What if you forget to take Valance 500 Solution

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

• Store the oral liquid at room temperature, ideally between 15°C and 30°C (59°F to 86°F).• Do not freeze the liquid, and keep it away from direct sunlight, high heat, and moisture.

Drug Warnings

  • Check the liquid before use: Inspect the liquid before each dose. Do not use it if the safety seal is broken or if you notice unusual cloudiness, discolouration, or particles that are not expected for the product.
  • Do not stop suddenly: Do not stop taking Valance 500 Solution abruptly without medical advice, even if you feel well. Sudden discontinuation of some antiseizure medicines can increase the risk of seizures, including prolonged or severe seizures.
  • Discuss pregnancy prevention: If you can become pregnant, talk to your doctor about the pregnancy-related risks of Valance 500 Solution and whether you need effective contraception during treatment. Do not stop the medicine or change your contraception without medical advice.
  • Attend recommended monitoring: Keep all appointments for blood tests or other monitoring recommended by your doctor. Depending on the medicine and your condition, these may include liver function, blood counts, or medicine levels.
  • Use caution with driving: Avoid driving, operating heavy machinery, or performing activities requiring full alertness until you know how Valance 500 Solution affects you, as it may cause drowsiness, dizziness, or reduced coordination in some people.

Drug-Drug Interactions

verifiedApollotooltip
  • Painkiller (e.g., aspirin): Can increase the concentration of Valance 500 Solution in your blood, raising the risk of side effects.
  • Other seizure medicines (e.g., phenytoin, carbamazepine, phenobarbital): Can change how your body processes Valance 500 Solution , or Valance 500 Solution may alter their levels, requiring careful dose adjustments.
  • Certain antibiotics (e.g., meropenem, imipenem): Can significantly lower the levels of Valance 500 Solution in your body, potentially making it ineffective.
  • Blood thinners (e.g., warfarin): Valance 500 Solution can increase the risk of bleeding when taken alongside these medications.
DivalproexGlycerol phenylbutyrate
Critical

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical
How does the drug interact with Valance 500 Oral Solution 200 ml:
Coadministration of Glycerol phenylbutyrate and Valance 500 Oral Solution 200 ml can increase ammonia levels in the blood.

How to manage the interaction:
Taking Glycerol phenylbutyrate and Valance 500 Oral Solution 200 ml together is generally avoided as it can lead to an interaction, it can be taken when your doctor advises. If you experience any symptoms like sudden dizziness, headaches, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Valance 500 Oral Solution 200 ml:
Coadministration of Valance 500 Oral Solution 200 ml and Lamotrigine can increase the risk and severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Valance 500 Oral Solution 200 ml and Lamotrigine, you can take these medicines together if prescribed by your doctor. However, contact your doctor if you experience restlessness, rash, or muscle weakness. Do not stop using any medications without a doctor's advice.
DivalproexSodium phenylbutyrate
Severe
How does the drug interact with Valance 500 Oral Solution 200 ml:
Co-administration of Sodium phenylbutyrate and Valance 500 Oral Solution 200 ml can increase ammonia levels in the blood and is generally not recommended for patients with urea cycle disorders.

How to manage the interaction:
Co-administration of Valance 500 Oral Solution 200 ml with Sodium phenylbutyrate can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
DivalproexVorinostat
Severe
How does the drug interact with Valance 500 Oral Solution 200 ml:
Coadministration of Valance 500 Oral Solution 200 ml and Vorinostat can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Valance 500 Oral Solution 200 ml and Vorinostat, you can take these medicines together if prescribed by your doctor. If you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Valance 500 Oral Solution 200 ml:
Coadministration of Ketoconazole and Valance 500 Oral Solution 200 ml may increase the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Valance 500 Oral Solution 200 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain, fatigue, nausea, vomiting, stomach pain, dark urine, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexBexarotene
Severe
How does the drug interact with Valance 500 Oral Solution 200 ml:
Co-administration of Valance 500 Oral Solution 200 ml and Bexarotene can increase the risk of pancreatitis (inflammation of the pancreas).

How to manage the interaction:
Co-administration of Valance 500 Oral Solution 200 ml and Bexarotene can lead to an interaction, but it can be taken when advised by your doctor. However, if you experience any symptoms like nausea, vomiting, or stomach cramps, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Valance 500 Oral Solution 200 ml:
Co-administration of Valance 500 Oral Solution 200 ml and teriflunomide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Valance 500 Oral Solution 200 ml and teriflunomide can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Valance 500 Oral Solution 200 ml:
Co-administration of Valance 500 Oral Solution 200 ml and Doripenem can reduce the blood levels of Valance 500 Oral Solution 200 ml sodium and increase the risk of developing seizures.

How to manage the interaction:
Co-administration of Valance 500 Oral Solution 200 ml with Doripenem can possibly result in an interaction, it can be taken when your doctor has advised it. Do not stop using any medications without first talking to your doctor.
DivalproexLomitapide
Severe
How does the drug interact with Valance 500 Oral Solution 200 ml:
Co-administration of Valance 500 Oral Solution 200 ml and Lomitapide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Valance 500 Oral Solution 200 ml and lomitapide can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like fever, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without the doctor's advice.
How does the drug interact with Valance 500 Oral Solution 200 ml:
Co-administration of buprenorphine with Valance 500 Oral Solution 200 ml may increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Buprenorphine with Valance 500 Oral Solution 200 ml can result in an interaction, it can be taken when a doctor has advised it. However, if you experience shortness of breath, irregular heart rhythms, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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  • Alcohol: Greatly increases central nervous system side effects, leading to extreme drowsiness, confusion, and dizziness.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

FAQs

Valance 500 Solution belongs to a group of medicines called anticonvulsants or antiepileptics, used to treat epilepsy (seizures/fits). It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures.
Valance 500 Solution contains 'Divalproex sodium,' which works by increasing the levels of a natural chemical in the brain called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, Valance 500 Solution helps control seizures.
Do not discontinue Valance 500 Solution without consulting your doctor. To treat your condition effectively, continue taking Valance 500 Solution for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Valance 500 Solution , your doctor will reduce the dose gradually to avoid worsening of seizures.
Valance 500 Solution may cause weight gain due to increased appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.
Use an effective method of contraception during the treatment with Valance 500 Solution . Avoid getting pregnant while taking Valance 500 Solution as it could lead to severe birth defects. Do not stop taking Valance 500 Solution and consult your doctor immediately if you become pregnant.
Valance 500 Solution may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising. Regular monitoring of blood count is advised while taking Valance 500 Solution .
Topiramate (an anticonvulsant) should not be taken along with Valance 500 Solution as it may cause hyperammonemia (excess ammonia in the blood), hypothermia (low body temperature), and liver problems.
Valance 500 Solution can indeed make you sleepy. This is a common side effect of the medication. If you're experiencing excessive drowsiness, please consult your doctor.
Yes, Valance 500 Solution can cause hair loss as a side effect. While this isn't a common side effect, it can occur in some people. If you notice significant hair loss while taking Valance 500 Solution , it's essential to consult with your doctor.
Yes, Valance 500 Solution can potentially damage your liver. While this is a rare side effect, being aware of the risk is essential. Signs of liver damage may include yellowing of the skin or eyes or jaundice, dark urine, abdominal pain, light-coloured stools, nausea and vomiting. If you experience any of these symptoms while taking Valance 500 Solution , seeking medical attention is crucial.
Avoid consumption of alcohol while taking Valance 500 Solution , as it may cause increased drowsiness and dizziness.
If you experience abdominal pain, nausea, and anorexia while taking Valance 500 Solution , it's essential to contact your doctor immediately. These symptoms can be signs of a severe side effect, such as liver damage.
An overdose of Valance 500 Solution can be a severe medical emergency. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you or someone you know has taken an overdose of Valance 500 Solution , please seek immediate medical attention.
The common side effects of Valance 500 Solution include drowsiness, dizziness, nausea, back pain, increased appetite, constipation, diarrhoea, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Do not take another dose right away without medical advice. Talk to your doctor or pharmacist to determine if you need to repeat the dose or wait until your next scheduled time.
Yes, your doctor will order regular blood tests to check your liver function, blood platelet levels, and the amount of Valance 500 Solution in your blood to ensure it remains at a safe and effective level.
If your medicine is a suspension, shaking the bottle well before each dose ensures that the active medicine is distributed evenly throughout the liquid. If you do not shake it, you may get too little or too much medicine in each dose.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - VAL0391
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