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compositionComposition:DIVALPROEX SODIUM-500MG
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Prescription Medicine
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D.V. Crono Oral Solution 100 ml is used to treat epilepsy (seizures/fits). It can be used alone or in combination with other medications to treat complex partial seizures that occur alone or alongside other types of seizures. It contains Divalproex sodium, which decreases the brain's excessive and abnormal nerve activity, thereby helping to control seizures. In some cases, it may cause common side effects such as drowsiness, dizziness, and nausea. Before taking this medicine, you should inform your doctor if you are allergic to any of its components, if you are pregnant/breastfeeding, and about all the medications you are taking, as well as any pre-existing medical conditions.

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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

DIVALPROEX SODIUM-500MG

Manufacturer/Marketer :

Bioapoyo

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About D.V. Crono Oral Solution 100 ml

D.V. Crono Oral Solution 100 ml is an oral liquid medicine prescribed to help manage and control brain-related conditions, including epilepsy and certain types of seizures. It is also used to stabilise moods during manic phases of bipolar disorder and to prevent severe migraine headaches from occurring. By helping to calm hyperactive signals in the brain, this medicine supports smoother daily functioning and improves long-term symptom management.

For this medicine to work effectively, you must take it consistently every day at the exact times prescribed by your doctor. It can be taken with or without food, though taking your dose with meals can help prevent stomach upset. Making supportive lifestyle adjustments, such as maintaining a consistent sleep schedule and keeping a daily symptom log, can greatly enhance your treatment outcomes.

While taking D.V. Crono Oral Solution 100 ml, you may experience common side effects like mild sleepiness, nausea, or dizziness. However, you should contact your doctor immediately if you experience serious symptoms such as severe stomach pain spreading to your back, dark urine, or yellowing of your skin or eyes. These can be early signs of rare but serious complications involving your pancreas or liver.

Before starting this medicine, tell your doctor if you have a history of liver problems, kidney disease, or certain metabolic disorders. Do not take this if you have active liver disease, a family history of severe liver dysfunction, or urea cycle disorders. It is also highly critical that women who are pregnant or planning to become pregnant avoid taking this medicine for migraine prevention due to severe risks to the unborn baby.

This medicine can interact with alcohol, tobacco, and other prescription medications, which may increase drowsiness or alter how well your body processes the treatment. If you are pregnant, breastfeeding, or an older adult, it is vital to consult your doctor or pharmacist to discuss safe usage, as special monitoring or alternative options may be required.

Uses of D.V. Crono Oral Solution 100 ml

D.V. Crono Oral Solution 100 ml is used in the treatment of epilepsy (seizures). The detailed uses of D.V. Crono Oral Solution 100 ml are as follows:

  • Epilepsy and Seizures: D.V. Crono Oral Solution 100 ml helps control various types of seizures by stabilising abnormal electrical activity in the brain, which reduces the frequency and severity of sudden episodes.
  • Bipolar Disorder (Manic Episodes): It treats periods of high energy, excitement, or irritability associated with manic phases, helping to restore a more balanced emotional state.
  • Migraine Prevention: It helps reduce the frequency of severe migraine headaches when taken daily as a long-term preventive measure.

Key Benefits

D.V. Crono Oral Solution 100 ml may provide therapeutic benefits in certain neurological conditions when used as prescribed by a doctor.
Benefits may include:

  • D.V. Crono Oral Solution 100 ml may help reduce the frequency of seizures in people for whom it has been prescribed, supporting better control of seizure-related symptoms.
  • When prescribed for bipolar disorder, D.V. Crono Oral Solution 100 ml may help manage episodes of mood changes and support greater emotional stability.
  • In patients prescribed this medicine for migraine prevention, D.V. Crono Oral Solution 100 ml may help reduce the frequency of migraine episodes and the number of days affected by migraine symptoms.
  • As an oral liquid formulation, D.V. Crono Oral Solution 100 ml may be easier to administer to children, older adults, or other patients who have difficulty swallowing tablets or capsules.

Directions for Use

  • D.V. Crono Oral Solution 100 ml can be taken with or without food, or as advised by the doctor.
  • Shake the bottle well before each use.
  • Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided with the pack.
  • Replace the bottle cap tightly after each use.
  • Avoid using regular household spoons, as they may not accurately measure the dose.
  • Your doctor may adjust the dose and frequency of this medication based on your medical condition.

How D.V. Crono Oral Solution 100 ml Works

D.V. Crono Oral Solution 100 ml works directly in the central nervous system to calm overactive nerve signals. In conditions like epilepsy, bipolar disorder, and migraines, certain nerve pathways in the brain can become overly excited, leading to seizures, extreme mood shifts, or headache triggers. This medicine helps by increasing the amount of a natural chemical messenger in the brain called gamma-aminobutyric acid (GABA). GABA acts as a natural brake system, blocking extra electrical signals and slowing down hyperactive nerve pathways. By boosting these calming signals, the medicine effectively prevents seizure activity, balances mood pathways, and reduces the brain excitability that triggers migraine attacks.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking D.V. Crono Oral Solution 100 ml, as it may cause increased drowsiness and dizziness.

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Pregnancy

Unsafe

D.V. Crono Oral Solution 100 ml belongs to pregnancy category D. Avoid taking D.V. Crono Oral Solution 100 ml if you are pregnant, as it could lead to serious birth defects. Consult your doctor for further advice.

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Breast Feeding

Caution

D.V. Crono Oral Solution 100 ml may pass into breastmilk. Consult your doctor before taking D.V. Crono Oral Solution 100 ml if you are breastfeeding.

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Driving

Unsafe

D.V. Crono Oral Solution 100 ml causes drowsiness and dizziness. Therefore, do not drive or operate machinery until you are mentally alert.

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Liver

Unsafe

D.V. Crono Oral Solution 100 ml should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns regarding this. Dose adjustment may be needed in patients with kidney impairment.

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Children

Caution

D.V. Crono Oral Solution 100 ml should be given to children only if prescribed by a doctor.

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Heart

Caution

Please inform your doctor if you have heart problems before taking D.V. Crono Oral Solution 100 ml, as there is limited information available on its safety in such cases.

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Geriatrics

Caution

D.V. Crono Oral Solution 100 ml can be taken if you're geriatric, but it requires careful monitoring and medical supervision.

What if I have taken an overdose of D.V. Crono Oral Solution 100 ml

If you or someone else takes too much of this medicine, seek immediate medical attention or contact your local poison control centre. Symptoms of a severe overdose may include extreme sleepiness, shallow breathing, weak muscles, or loss of consciousness.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink enough fluids throughout the day, unless your doctor has advised you to restrict fluids. Maintaining adequate hydration can support overall health during treatment.
  • Track your symptoms: Keep a seizure, mood, or migraine diary, as appropriate for your condition. Recording symptoms, triggers, and changes over time can help your doctor assess your response to treatment.
  • Limit or avoid alcohol: Alcohol may increase drowsiness or dizziness with some medicines and can affect seizure control or migraine symptoms in some people. Ask your doctor whether alcohol is safe for you while taking D.V. Crono Oral Solution 100 ml.
  • Maintain a balanced diet: Follow a varied, nutritious diet and monitor any significant changes in appetite or weight. Inform your doctor if you notice persistent or unexpected weight changes during treatment.
  • Maintain a regular sleep schedule: Aim for consistent sleep and wake times, as inadequate or irregular sleep may trigger seizures or migraine episodes in some people.
health query

Have a query?

How Soon It Starts Working

  • The time required for D.V. Crono Oral Solution 100 ml to start to work: D.V. Crono Oral Solution 100 ml ideally shows its action within 15 minutes to 2 hours after administration.
  • The time for which the effects of D.V. Crono Oral Solution 100 ml last: The effect of D.V. Crono Oral Solution 100 ml lasts for 4 to 6 hours.

What if you forget to take D.V. Crono Oral Solution 100 ml

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

• Store the oral liquid at room temperature, ideally between 15°C and 30°C (59°F to 86°F).• Do not freeze the liquid, and keep it away from direct sunlight, high heat, and moisture.

Drug Warnings

  • Check the liquid before use: Inspect the liquid before each dose. Do not use it if the safety seal is broken or if you notice unusual cloudiness, discolouration, or particles that are not expected for the product.
  • Do not stop suddenly: Do not stop taking D.V. Crono Oral Solution 100 ml abruptly without medical advice, even if you feel well. Sudden discontinuation of some antiseizure medicines can increase the risk of seizures, including prolonged or severe seizures.
  • Discuss pregnancy prevention: If you can become pregnant, talk to your doctor about the pregnancy-related risks of D.V. Crono Oral Solution 100 ml and whether you need effective contraception during treatment. Do not stop the medicine or change your contraception without medical advice.
  • Attend recommended monitoring: Keep all appointments for blood tests or other monitoring recommended by your doctor. Depending on the medicine and your condition, these may include liver function, blood counts, or medicine levels.
  • Use caution with driving: Avoid driving, operating heavy machinery, or performing activities requiring full alertness until you know how D.V. Crono Oral Solution 100 ml affects you, as it may cause drowsiness, dizziness, or reduced coordination in some people.

verifiedApollotooltip
  • Painkiller (e.g., aspirin): Can increase the concentration of D.V. Crono Oral Solution 100 ml in your blood, raising the risk of side effects.
  • Other seizure medicines (e.g., phenytoin, carbamazepine, phenobarbital): Can change how your body processes D.V. Crono Oral Solution 100 ml, or D.V. Crono Oral Solution 100 ml may alter their levels, requiring careful dose adjustments.
  • Certain antibiotics (e.g., meropenem, imipenem): Can significantly lower the levels of D.V. Crono Oral Solution 100 ml in your body, potentially making it ineffective.
  • Blood thinners (e.g., warfarin): D.V. Crono Oral Solution 100 ml can increase the risk of bleeding when taken alongside these medications.

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verifiedApollotooltip
  • Alcohol: Greatly increases central nervous system side effects, leading to extreme drowsiness, confusion, and dizziness.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

FAQs

D.V. Crono Oral Solution 100 ml belongs to a group of medicines called anticonvulsants or antiepileptics, used to treat epilepsy (seizures/fits). It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures.
D.V. Crono Oral Solution 100 ml contains 'Divalproex sodium,' which works by increasing the levels of a natural chemical in the brain called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, D.V. Crono Oral Solution 100 ml helps control seizures.
Do not discontinue D.V. Crono Oral Solution 100 ml without consulting your doctor. To treat your condition effectively, continue taking D.V. Crono Oral Solution 100 ml for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking D.V. Crono Oral Solution 100 ml, your doctor will reduce the dose gradually to avoid worsening of seizures.
D.V. Crono Oral Solution 100 ml may cause weight gain due to increased appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.
Use an effective method of contraception during the treatment with D.V. Crono Oral Solution 100 ml. Avoid getting pregnant while taking D.V. Crono Oral Solution 100 ml as it could lead to severe birth defects. Do not stop taking D.V. Crono Oral Solution 100 ml and consult your doctor immediately if you become pregnant.
D.V. Crono Oral Solution 100 ml may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising. Regular monitoring of blood count is advised while taking D.V. Crono Oral Solution 100 ml.
Topiramate (an anticonvulsant) should not be taken along with D.V. Crono Oral Solution 100 ml as it may cause hyperammonemia (excess ammonia in the blood), hypothermia (low body temperature), and liver problems.
D.V. Crono Oral Solution 100 ml can indeed make you sleepy. This is a common side effect of the medication. If you're experiencing excessive drowsiness, please consult your doctor.
Yes, D.V. Crono Oral Solution 100 ml can cause hair loss as a side effect. While this isn't a common side effect, it can occur in some people. If you notice significant hair loss while taking D.V. Crono Oral Solution 100 ml, it's essential to consult with your doctor.
Yes, D.V. Crono Oral Solution 100 ml can potentially damage your liver. While this is a rare side effect, being aware of the risk is essential. Signs of liver damage may include yellowing of the skin or eyes or jaundice, dark urine, abdominal pain, light-coloured stools, nausea and vomiting. If you experience any of these symptoms while taking D.V. Crono Oral Solution 100 ml, seeking medical attention is crucial.
Avoid consumption of alcohol while taking D.V. Crono Oral Solution 100 ml, as it may cause increased drowsiness and dizziness.
If you experience abdominal pain, nausea, and anorexia while taking D.V. Crono Oral Solution 100 ml, it's essential to contact your doctor immediately. These symptoms can be signs of a severe side effect, such as liver damage.
An overdose of D.V. Crono Oral Solution 100 ml can be a severe medical emergency. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you or someone you know has taken an overdose of D.V. Crono Oral Solution 100 ml, please seek immediate medical attention.
The common side effects of D.V. Crono Oral Solution 100 ml include drowsiness, dizziness, nausea, back pain, increased appetite, constipation, diarrhoea, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Do not take another dose right away without medical advice. Talk to your doctor or pharmacist to determine if you need to repeat the dose or wait until your next scheduled time.
Yes, your doctor will order regular blood tests to check your liver function, blood platelet levels, and the amount of D.V. Crono Oral Solution 100 ml in your blood to ensure it remains at a safe and effective level.
If your medicine is a suspension, shaking the bottle well before each dose ensures that the active medicine is distributed evenly throughout the liquid. If you do not shake it, you may get too little or too much medicine in each dose.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 018081S056Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Valproic Acid Oral Solution Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. MedlinePlus. A682412 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  4. Sodium valproate: medicine to treat epilepsy and bipolar disorder [Internet]. nhs.uk. 2025 [Accessed on 10 April 2025]Check here
  5. CDSCO [Internet]. Cdscoonline.gov.in. 2025 [Accessed on 10 April 2025]Check here
  6. Divaa. [Accessed on 02 Jun. 2026]Check here
  7. Sanofi India — Pharmaceutical Products. Sanofi.com [Internet]. [Accessed on 2026 Jan 1]Check here

Country of origin

India

Manufacturer/Marketer address

350, HSIDC, Barhi, 131101
Other Info - DVC0004

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