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compositionComposition:SEMAGLUTIDE-7MG
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Rybelsus 7 mg Tablet is an antidiabetic medication used to improve glycaemic control in adult patients with type 2 diabetes mellitus when diet and exercise are not enough or when the other medicines are not enough to control your blood sugar levels. It works by promoting glycemic control via insulin secretion, and reducing postprandial glucagon secretion

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

SEMAGLUTIDE-7MG

Manufacturer/Marketer :

Novo Nordisk India Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Rybelsus 7 mg Tablet

Rybelsus 7 mg Tablet is a prescription medicine used to lower blood sugar levels in adults with type 2 diabetes. It is prescribed as an aid to diet and exercise to improve glycaemic control and manage this chronic condition. It helps keep your blood sugar in a healthy target range.

This medicine must be taken once daily at the same time every day to maintain consistent blood sugar control. You should take it first thing in the morning on an empty stomach with a small sip of plain water, waiting at least 30 minutes before eating, drinking, or taking other oral medicines. Combining this routine with a balanced diet and regular physical activity is key to achieving the best results.

Some people taking this medicine may experience common side effects such as mild nausea, vomiting, diarrhoea, or a decreased appetite. While these stomach-related symptoms are often temporary, you should contact your doctor right away if you experience severe, persistent stomach pain or sudden changes in your vision.

Before starting this medicine, talk to your doctor if you have a history of kidney disease, pancreatitis, or diabetic retinopathy. Do not take this if you or anyone in your family has ever had a type of thyroid cancer called medullary thyroid carcinoma, or if you have Multiple Endocrine Neoplasia syndrome type 2.

This medicine can interact with other oral drugs by slowing down how fast your stomach empties, which may reduce how well your body absorbs those medicines. Pregnant women, those planning to become pregnant, breastfeeding mothers, or elderly individuals should consult their doctor before starting treatment to ensure it is safe for them.

Uses of Rybelsus 7 mg Tablet

Rybelsus 7 mg Tablet is used to manage type 2 diabetes and improve blood sugar control when combined with healthy lifestyle changes. The detailed uses of Rybelsus 7 mg Tablet are as follows:

  • Type 2 Diabetes Mellitus: Rybelsus 7 mg Tablet is used to improve blood sugar control in adults with type 2 diabetes when combined with healthy lifestyle changes.
  • Cardiovascular Risk Management: In certain adults with type 2 diabetes and heart disease, this type of medicine helps reduce the risk of serious heart problems like heart attacks or strokes.

Key Benefits

Rybelsus 7 mg Tablet offers several clinical benefits that help you manage your health and feel better daily.

  • Convenient Oral Alternative: It provides the benefits of advanced blood sugar control in a daily tablet, removing the need for daily injections.
  • Effective HbA1c Reduction: It helps lower your long-term blood sugar level (HbA1c), which reduces the risk of long-term diabetes complications.
  • Post-Meal Sugar Control: It prevents sudden blood sugar spikes after you eat by helping your body release insulin when it is needed most.
  • Potential Weight Management: Many patients experience modest weight reduction as a supportive benefit, though it is not a primary weight-loss drug.
Side effects of Rybelsus 7 mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Directions for Use

  • Take Rybelsus 7 mg Tablet exactly as directed by your doctor, either with or without food. Swallow the tablet whole with a full glass of water.
  • Do not crush, chew, or break the medicine, as this can interfere with how the medication works.
  • Finish the entire course of treatment, even if you start feeling better, to ensure the infection is fully treated.
  • Stopping the medication early or adjusting the dose without consulting your doctor can lead to the infection not being completely cleared and may cause resistance.

How Rybelsus 7 mg Tablet Works

Rybelsus 7 mg Tablet contains semaglutide, which works by mimicking the action of a natural hormone in your body called GLP-1. When you eat, this hormone is normally released to help manage your blood sugar levels, but people with type 2 diabetes may not produce enough of it. By acting like this natural hormone, the medicine helps your pancreas release the right amount of insulin when your blood sugar is high. At the same time, it stops your liver from producing too much extra sugar, preventing unwanted spikes between meals. Additionally, it slows down the rate at which food moves through your stomach. This slower digestion helps you feel full for longer periods, which naturally helps reduce your overall food intake and supports steady blood sugar levels throughout the day.
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Alcohol

Unsafe

It is advised to avoid alcohol intake since it may worsen the side effects like lactic acidosis and increase the risk of developing low blood sugar levels.

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Pregnancy

Caution

Rybelsus 7 mg Tablet is not recommended during pregnancy, as it is unknown if it affects your unborn baby. Please discuss this with your doctor if you have any concerns regarding this.

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Breast Feeding

Consult your doctor

Rybelsus 7 mg Tablet should not be used if you are breastfeeding because it is unknown whether it goes into breast milk. Please discuss this with your doctor if you have any concerns regarding this.

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Driving

Caution

Caution should be exercised. If your blood sugar is too low or too high, your driving ability may be affected. Do not drive if these symptoms appear.

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Liver

Consult your doctor

Limited information was available for the use of Rybelsus 7 mg Tablet in patients suffering from liver impairment. Please consult your doctor if you have any concerns regarding using Rybelsus 7 mg Tablet in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Consult your doctor

Caution should be exercised in people with kidney impairment while using Rybelsus 7 mg Tablet . Inform your doctor before taking the Rybelsus 7 mg Tablet if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Rybelsus 7 mg Tablet is not indicated for children and adolescents under 18 since the safety and efficacy in this age range have not been verified.

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Heart

Safe if prescribed

Rybelsus 7 mg Tablet is generally considered safe for heart patients. However, please consult your doctor before using Rybelsus 7 mg Tablet .

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Geriatrics

Safe if prescribed

Rybelsus 7 mg Tablet is generally considered safe for use in geriatric patients; however, significant precautions should be taken due to age-related sensitivities.

What if I have taken an overdose of Rybelsus 7 mg Tablet

If you take more than your prescribed dose, seek immediate medical attention. An overdose can cause severe nausea, persistent vomiting, or very low blood sugar levels.

Diet & Lifestyle Advise

  • Eat a low-glycemic diet: Focus on fibre-rich vegetables, whole grains, lean proteins, and healthy fats to help maintain stable blood sugar levels.
  • Stay hydrated carefully: Drink plenty of water throughout the day to avoid dehydration, which is especially important if you experience nausea or diarrhoea. Remember to only use plain water when taking your daily tablet.
  • Engage in regular physical activity: Aim for at least 150 minutes of moderate exercise, such as brisk walking, swimming, or cycling, each week to help your body use insulin more efficiently.
  • Eat smaller, more frequent meals: If you feel nauseous or get full very quickly, reducing your portion sizes and eating slowly can help manage these stomach symptoms.

Health Queries

What is type 2 diabetes, and what medications are commonly prescribed to treat it?

Chandrakanta Jena

Chandrakanta Jena

Pharm D

Type 2 diabetes is a manageable condition where your body struggles to use insulin effectively, causing blood sugar levels to rise. To help manage this, doctors commonly prescribe medications alongside lifestyle changes. First-line treatment is usually metformin, which helps your body use its own insulin better. Other common options include SGLT2 inhibitors (like empagliflozin) that help kidneys filter out excess sugar, GLP-1 receptor agonists (like semaglutide) to regulate insulin release, and sulfonylureas (like glipizide) to stimulate insulin production. Sometimes, insulin therapy is also used. These medications work in different ways to keep you healthy, and your doctor will tailor the best plan for you.

Are there any medicines to reduce belly fat?

Chandrakanta Jena

Chandrakanta Jena

Pharm D

There are no medicines that specifically target belly fat. However, some prescription medications, such as Semaglutide, Liraglutide, Orlistat, and Tirzepatide, may help reduce overall body fat, including around the waist, by suppressing appetite or reducing fat absorption. They are most effective when combined with a balanced diet, regular exercise, and healthy lifestyle habits, and should only be taken under a doctor?s supervision.
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How Soon It Starts Working

The time required for Rybelsus 7 mg Tablet to start to work: Rybelsus 7 mg Tablet ideally shows its action within 1 hour after administration. The time for which the effects of Rybelsus 7 mg Tablet last: The duration of action for Rybelsus 7 mg Tablet is unknown.

What if you forget to take Rybelsus 7 mg Tablet

If you miss a dose of Rybelsus 7 mg Tablet , skip the missed dose entirely. Take your next dose the following morning at your usual time. Do not take a double dose or extra tablets to make up for the missed one.

Storage

•Store Rybelsus 7 mg Tablet tablets in their original blister pack until the exact moment you are ready to take one.•This is critical because the tablets are highly sensitive to moisture and will lose their effectiveness if exposed to the air.

Drug Warnings

  • Timing Before Food: Always wait a full 30 minutes after taking Rybelsus 7 mg Tablet before you drink coffee, tea, or eat breakfast, as failing to wait will significantly reduce the medicine's absorption.
  • Storage Precautions: Never store these tablets in a standard daily or weekly pill organiser; they must remain sealed in their protective blister sheets until use.
  • Dehydration Warning: If you experience severe vomiting or diarrhoea that does not stop, contact your doctor immediately to prevent dehydration, which can lead to sudden kidney damage.
  • Thyroid Warning Signs: Be alert for any new throat swelling, trouble swallowing, or voice changes, and seek medical attention right away if these occur.
  • Medical Procedure Information: Inform any surgeon or dentist that you are taking Rybelsus 7 mg Tablet well before any scheduled procedure, as this medicine slows stomach emptying and may affect fasting guidelines.

Drug-Drug Interactions

verifiedApollotooltip
  • Insulin or sulfonylureas: Taking Rybelsus 7 mg Tablet alongside these medicines may increase the risk of low blood sugar. Your doctor may need to adjust your other doses to prevent this.
  • Other oral medicines: Because Rybelsus 7 mg Tablet delays stomach emptying, it can change how your body absorbs other pills. Take other oral medicines at least 30 minutes after your Rybelsus 7 mg Tablet dose.
SemaglutideGatifloxacin
Critical
SemaglutideBexarotene
Severe

Drug-Drug Interactions

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SemaglutideGatifloxacin
Critical
How does the drug interact with Rybelsus 7 mg Tablet:
Coadministration of Rybelsus 7 mg Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Rybelsus 7 mg Tablet can be taken with Gatifloxacin if prescribed by the doctor. Consult the doctor if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue any medications without first consulting your doctor.
SemaglutideBexarotene
Severe
How does the drug interact with Rybelsus 7 mg Tablet:
Co-administration of Bexarotene and Rybelsus 7 mg Tablet can increase the risk of pancreatitis (inflammation of the pancreas).

How to manage the interaction:
Co-administration of Bexarotene and Rybelsus 7 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like persistent nausea, vomiting, abdominal tenderness, and upper abdominal pain, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Rybelsus 7 mg Tablet when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

FAQs

Rybelsus 7 mg Tablet is used to improve glycaemic control in adult patients with type 2 diabetes mellitus when diet and exercise are not enough or when the other medicines are not enough to control your blood sugar levels.
Rybelsus 7 mg Tablet contains semaglutide. Semaglutide is a GLP-1 hormone that enhances glycemic control through various mechanisms, including insulin secretion, slowing gastric emptying, and decreasing postprandial glucagon secretion. This drug is frequently paired with dietary and exercise changes. Altogether Rybelsus 7 mg Tablet reduces sugar levels in the body.
Low blood glucose levels are referred to as hypoglycaemia. Rybelsus 7 mg Tablet may result in hypoglycaemia. Hypoglycaemia can occur if you skip or delay eating, drink alcohol, exercise strenuously, or take other diabetes medications in addition to Rybelsus 7 mg Tablet .
Do not stop taking Rybelsus 7 mg Tablet without first consulting your doctor. Take Rybelsus 7 mg Tablet for as long as the doctor has instructed. Consult a doctor if you have any problems while taking Rybelsus 7 mg Tablet .
Take the missed dose as soon as you remember. If it is time for the next scheduled dose, skip the missing dose and resume your regular dosing regimen. Do not double the dose.
Caution should be exercised if you have severe and ongoing pain in the stomach area. It is recommended to consult a doctor immediately, as this could signify an inflamed pancreas (acute pancreatitis). Your doctor will weigh the benefits and potential risks before prescribing this medication.
Rybelsus 7 mg Tablet is not recommended to treat type 1 diabetes (your body produces no insulin).
Rybelsus 7 mg Tablet should not be used if you have type 1 diabetes or diabetic ketoacidosis or if you are allergic to Semaglutide or any of the other ingredients of this medicine.
Rybelsus 7 mg Tablet can be taken with other diabetes medications if prescribed by the doctor. However, taking Rybelsus 7 mg Tablet with other diabetes medications may increase the risk of hypoglycaemia (low blood sugar).
Rybelsus 7 mg Tablet may cause serious adverse effects like thyroid C-cell tumours, pancreatitis, diabetic retinopathy complications, acute kidney injury, hypersensitivity, and acute gall bladder disease. Consult the doctor if you notice any unusual symptoms.
Though Rybelsus 7 mg Tablet is not indicated for weight loss, it may help you lose some weight. However, Rybelsus 7 mg Tablet should not be used for weight loss as it is used to treat type 2 diabetes.
Rybelsus 7 mg Tablet is not recommended for use during pregnancy and lactation as it might cause foetal harm and potentially serious adverse reactions in breastfed infants.
Rybelsus 7 mg Tablet should be stored at room temperature (20°C to 25°C) in a dry place away from moisture. Keep it out of sight and reach of children.
Consult the doctor if any of the side effects bother you or do not go away. The doctor will guide you appropriately.
Rybelsus 7 mg Tablet should be taken on an empty stomach when you first wake up. It should be swallowed as a whole with water; do not crush, split or chew it. You can eat or drink 30 minutes after taking Rybelsus 7 mg Tablet .
Rybelsus 7 mg Tablet may cause side effects such as nausea, vomiting, diarrhoea, abdominal pain, decreased appetite, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, if the side effects persist or worsen, consult your doctor.
You should inform the doctor if you get eye problems, such as changes in vision, during treatment with this medicine as the Rybelsus 7 mg Tablet may lead to complications of diabetic eye disease (retinopathy). When taking this medication, you may feel nauseous, sick (vomiting), or have diarrhoea. These adverse effects may result in dehydration (loss of fluids). You must consume enough water to avoid dehydration, especially if you have kidney issues.
Concomitant use of Rybelsus 7 mg Tablet with other medicines like sulfonylureas or insulin may cause hypoglycaemia. Also, as Rybelsus 7 mg Tablet can delay gastric emptying, it can impact the absorption of other medicines like levothyroxine. Hence, it is advised to consult the doctor and follow administration instructions if you are taking any other medicines.
No, you must take Rybelsus 7 mg Tablet only with a small sip of plain water (up to 4 ounces). Taking it with coffee, tea, juice, or food will prevent your body from absorbing the medicine properly. Wait at least 30 minutes after taking your tablet before having your morning coffee. Talk to your doctor or pharmacist if you have trouble adjusting this routine.
Mild nausea is a common side effect when you first start taking Rybelsus 7 mg Tablet or when your dose is increased. It often improves over a few weeks. To manage it, try eating smaller meals, avoiding fatty or highly sweet foods, and staying upright after eating. If your nausea is severe or does not go away, talk to your doctor.
It is best to limit or avoid alcohol while taking Rybelsus 7 mg Tablet . Alcohol can affect your blood sugar levels and increase your risk of low blood sugar or pancreatic irritation. Talk to your doctor about what is safe for you.
The tablets are highly sensitive to moisture in the air. If you remove them from the blister packaging ahead of time, such as putting them in a weekly pill box, they can lose their strength and may not work. Only remove a tablet from the blister pack right when you are ready to take it.
No, Rybelsus 7 mg Tablet is not insulin. It is a GLP-1 receptor agonist that helps your body use its own natural insulin more effectively when blood sugar levels are high. It is taken as an oral tablet, unlike many other GLP-1 medicines, which are injections.

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Reference

  1. Electronic Medicines Compendium (EMC). Pil.11507 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. DrugBank Online. Db13928 Clinical & Chemical Summary. Edmonton, AB: DrugBank; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Semaglutide Drug Interactions Database Summary. Auckland, NZ: Drugs.com Clinical Review Team; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Roder ME. Clinical potential of treatment with semaglutide in type 2 diabetes patients. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. December 2019. [Accessed on 25th March 2026]Check here
  5. Novo Nordisk A/S. Electronic Medicines Compendium (EMC). [Revised in January 2026] [Accessed on 25th March 2026]Check here
  6. Semaglutide [Prescribing Information]. 2024. [Accessed on 10 Oct. 2024]Check here

Country of origin

India

Manufacturer/Marketer address

Plot No.32, 47-50, Epip Area, Whitefield, Bangalore - 560 066
Other Info - RYB0005
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