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  3. Reglan Injection 5 x 2 ml

Reglan Injection 5 x 2 ml , Pack of 5 InjectionS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Reglan Injection 5 x 2 ml is an anti-emetic medication used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, migraine, and post-operative conditions. It contains metoclopramide which increases the motility of the upper gastrointestinal tract and thus helps in gastric emptying. Some of the common side effects include fatigue, dizziness, headache, and bowel disturbances.
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Composition :

METOCLOPRAMIDE-5MG

Manufacturer/Marketer :

Cfl Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Reglan Injection 5 x 2 ml

Reglan Injection 5 x 2 ml belongs to a group of medicines called anti-emetics and prokinetic agents used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, migraine, and in post-operative conditions. Additionally, Reglan Injection 5 x 2 ml is also used to treat delayed gastric emptying. Reglan Injection 5 x 2 ml may be used to facilitate small bowel intubation and to stimulate gastric emptying and intestinal transit of barium.

Reglan Injection 5 x 2 ml contains ‘metoclopramide’ that works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and treats gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

In some cases, Reglan Injection 5 x 2 ml may cause common side-effects such as drowsiness, fatigue, dizziness, headache, and bowel disturbances. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Consult your doctor if you are pregnant or breastfeeding. Reglan Injection 5 x 2 ml may cause drowsiness and dizziness affecting your ability to drive and operate machinery. Reglan Injection 5 x 2 ml is not recommended for children below one year. Avoid consuming alcohol while on treatment with Reglan Injection 5 x 2 ml as it could lead to increased drowsiness. Treatment with Reglan Injection 5 x 2 ml is not recommended for longer than 12 weeks, except in rare cases.

Uses of Reglan Injection 5 x 2 ml

Treatment of Nausea, vomiting and delayed gastric emptying

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Reglan Injection 5 x 2 ml will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Reglan Injection 5 x 2 ml belongs to a group of medicines called anti-emetics and prokinetic agents used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, migraine, and in post-operative conditions. Additionally, Reglan Injection 5 x 2 ml is also used to treat delayed gastric emptying. Reglan Injection 5 x 2 ml may be used to facilitate small bowel intubation and to facilitate gastric emptying and intestinal transit of barium in patients where delayed emptying interrupts radiological examination of the stomach and/or small intestine. Reglan Injection 5 x 2 ml contains ‘metoclopramide’ that works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and treats gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

How Reglan Injection 5 x 2 ml Works

Reglan Injection 5 x 2 ml contains ‘metoclopramide’ that works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and treats gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

Storage

• Store in a cool and dry place away from sunlight.• Keep Reglan Injection 5 x 2 ml out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Reglan Injection 5 x 2 ml
  • Stretching and walking are examples of mild exercises that can improve mobility and reduce muscle stiffness.
  • Improving posture, mobility, and muscle coordination through physical therapy can help manage slowness or stiffness.
  • Maintain healthy weight and advance general health depend on eating a balanced diet.
  • Reducing symptoms like tremors or muscle spasms requires adequate sleep and rest.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

What if I have taken an overdose of Reglan Injection 5 x 2 ml

Reglan Injection 5 x 2 ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include drowsiness, disorientation and extrapyramidal reactions. Your doctor may take immediate necessary measures if an overdose is suspected.

Drug Warnings

Do not take Reglan Injection 5 x 2 ml if you are allergic to any of its components; if you have gastrointestinal bleeding, mechanical obstruction/perforation, pheochromocytoma (tumour in the adrenal glands), or epilepsy. Reglan Injection 5 x 2 ml may cause neuroleptic malignant syndrome (a nervous disorder with high fever and muscle stiffness), extrapyramidal symptoms (shaking, tremor, stiffness and involuntary movement), Tardive dyskinesia (movement disorder), Parkinson-like symptoms (bradykinesia, tremor, cogwheel rigidity, or mask-like facies), and depression. Inform your doctor if you have heart problems, diabetes, depression, high blood pressure, breast cancer, seizures, Parkinson’s disease, methaemoglobinaemia, or liver or kidney problems. Consult your doctor immediately if you cannot stop or control movements like shaking your arms and legs, blinking and moving your eyes, sticking out the tongue, frowning, lip-smacking, chewing, or puckering up the mouth.

Drug-Drug Interactions

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MetoclopramideLurasidone
Critical
MetoclopramideVenlafaxine
Critical

Drug-Drug Interactions

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MetoclopramideLurasidone
Critical
How does the drug interact with Reglan Injection 5 x 2 ml :
The combination of Lurasidone and Reglan Injection 5 x 2 ml may result in significantly increased Lurasidone blood levels. This may raise the possibility of undesirable consequences such as Parkinson's disease. (It is a neurological condition that causes uncontrollable movements)and Tardive dyskinesia (uncontrollable movements, particularly of the lower face).

How to manage the interaction:
Lurasidone and Reglan Injection 5 x 2 ml is not recommended, as they may interact, but can be used if a doctor prescribes them. Consult a doctor if you have muscle spasms, or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning, tongue thrusting, teeth clenching, jaw twitching, jitteriness, restlessness, pacing, and foot tapping. Do not stop taking any medications without visiting a doctor.
MetoclopramideVenlafaxine
Critical
How does the drug interact with Reglan Injection 5 x 2 ml :
Coadministration of Reglan Injection 5 x 2 ml with Venlafaxine might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Reglan Injection 5 x 2 ml with Venlafaxine together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideAmisulpride
Critical
How does the drug interact with Reglan Injection 5 x 2 ml :
Taking Reglan Injection 5 x 2 ml with Amisulpride may increase the risk or severity of side effects.

How to manage the interaction:
Taking Amisulpride with Reglan Injection 5 x 2 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
MetoclopramideParoxetine
Critical
How does the drug interact with Reglan Injection 5 x 2 ml :
Using Reglan Injection 5 x 2 ml with Paroxetine can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhoea) to severe (muscle rigidity, fever, and seizures).

How to manage the interaction:
Taking Reglan Injection 5 x 2 ml with Paroxetine is not recommended, as it can possibly lead to an interaction, it can be taken if prescribed by your doctor. Do not stop using any medications without a doctor’s advice.
MetoclopramidePromethazine
Critical
How does the drug interact with Reglan Injection 5 x 2 ml :
Coadministration of Reglan Injection 5 x 2 ml with Promethazine can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Promethazine with Reglan Injection 5 x 2 ml is generally avoided as it can possibly result in an interaction. They can be taken together However, consult a doctor if you experience puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping. Do not stop taking any medications without consulting a doctor.
MetoclopramideBupropion
Critical
How does the drug interact with Reglan Injection 5 x 2 ml :
Co-administration of Reglan Injection 5 x 2 ml with Bupropion can increase the levels of Reglan Injection 5 x 2 ml and increase the risk or severity of developing seizures (fits).

How to manage the interaction:
Taking Reglan Injection 5 x 2 ml with Bupropion is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideProchlorperazine
Critical
How does the drug interact with Reglan Injection 5 x 2 ml :
Coadministration of Reglan Injection 5 x 2 ml and prochlorperazine can increase the risk of side effects.

How to manage the interaction:
Taking Reglan Injection 5 x 2 ml with Prochlorperazine together is generally avoided as it can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience muscle spasm or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult the doctor. Do not stop taking any medications without consulting a doctor.
MetoclopramideZiprasidone
Critical
How does the drug interact with Reglan Injection 5 x 2 ml :
Taking Reglan Injection 5 x 2 ml with Ziprasidone can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Reglan Injection 5 x 2 ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience lip-smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping. Do not discontinue any medications without consulting a doctor.
MetoclopramideDuloxetine
Critical
How does the drug interact with Reglan Injection 5 x 2 ml :
Coadministration of Reglan Injection 5 x 2 ml with duloxetine increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Reglan Injection 5 x 2 ml with Duloxetine is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
MetoclopramideTetrabenazine
Critical
How does the drug interact with Reglan Injection 5 x 2 ml :
Coadministration of Tetrabenazine and Reglan Injection 5 x 2 ml can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Tetrabenazine and Reglan Injection 5 x 2 ml together is not recommended as it can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, restlessness, and foot tapping, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Drink fluids to stay hydrated.
  • Avoid solid foods until vomiting stops.
  • Avoid foods that might cause stomach upset.
  • Take ample rest. Avoid any activity immediately after eating.
  • Consume plain, light foods such as bread and biscuits.
  • Avoid food with strong flavours and fried food.
  • Ginger tea might help in proper digestion.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Reglan Injection 5 x 2 ml Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while on treatment with Reglan Injection 5 x 2 ml as it may cause increased sleepiness and drowsiness.

bannner image

Pregnancy

Caution

Consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

Reglan Injection 5 x 2 ml may be excreted in human milk. Consult your doctor if you are breastfeeding.

bannner image

Driving

Caution

Reglan Injection 5 x 2 ml may cause dizziness and drowsiness. Do not drive or operate machinery until you know how Reglan Injection 5 x 2 ml affects you.

bannner image

Liver

Caution

Dose adjustment may be needed. Consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed. Consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Caution

Reglan Injection 5 x 2 ml is not recommended for children below one year.

Have a query?

FAQs

Reglan Injection 5 x 2 ml belongs to a group of medicines called anti-emetics and prokinetic agents used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, migraine, and in post-operative conditions. Additionally, Reglan Injection 5 x 2 ml is also used to treat delayed gastric emptying.

Reglan Injection 5 x 2 ml works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and treats gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

Reglan Injection 5 x 2 ml may cause tardive dyskinesia (movement disorder) that is often irreversible. The risk increases with the duration of treatment and dosage. Reglan Injection 5 x 2 ml therapy should be discontinued in patients who develop the symptoms of tardive dyskinesia. Consult your doctor immediately if you notice symptoms such as involuntary movements of the face, tongue, mouth, jaw, trunk and/or extremities.

Reglan Injection 5 x 2 ml may be used to facilitate small bowel intubation (the process of passing a small, flexible plastic tube through the nose/mouth into the stomach/small intestine) in adults and pediatric patients in whom the tube does not pass the pylorus (the opening from the stomach into the duodenum) with conventional manoeuvres.

Treatment with Reglan Injection 5 x 2 ml should be avoided for longer than 12 weeks except in rare cases where benefits outweigh the risks of developing tardive dyskinesia.

Reglan Injection 5 x 2 ml may cause depression in people with or without a medical history of depression. Consult your doctor immediately if you have any suicidal thoughts, such as killing or harming yourself.

Reglan Injection 5 x 2 ml may be used to facilitate gastric emptying and intestinal transit of barium in patients where delayed emptying interrupts radiological examination of the stomach and/or small intestine.

Country of origin

INDIA

Manufacturer/Marketer address

DEMPO TOWERS 5TH FLOOREDC PATTO PLAZA PANJIM GOA GA 403001 IN
Other Info - REG0011

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:01 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/017862s063lbl.pdf
  2. https://www.ema.europa.eu/en/documents/referral/metoclopramide-article-31-referral-annex-iii_en-0.pdf
  3. https://www.sandoz.ca/sites/www.sandoz.ca/files/Metoclopramide%20HCl%20PMe%2020141118.pdf

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