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Numlo D 2.5 Tablet is used to treat hypertension (high blood pressure). It contains Amlodipine and Hydrochlorothiazide, which relax and widen blood vessels. Also, it helps to remove extra water and certain electrolytes from the body through urine. Thus, it lowers high blood pressure and reduces the chances of future heart attack and stroke. It may cause side effects such as glucose intolerance (low or high level of glucose), ankle swelling, sleepiness, headache, (sense of heat in the face, ears, neck, and trunk), flushing, tiredness, nausea, decreased potassium level in the blood, increased blood uric acid, and altered blood lipid level.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Numlo D 2.5 Tablet

Numlo D 2.5 Tablet is a prescription oral medication used to treat high blood pressure (hypertension). By lowering elevated blood pressure, this medicine helps prevent serious cardiovascular events like strokes, heart attacks, and kidney problems.

To get the most benefit, you should take Numlo D 2.5 Tablet consistently at the same time every single day, exactly as prescribed by your doctor. You can take this tablet with or without food. Combining this medicine with a low-sodium diet, regular exercise, and maintaining a healthy weight will greatly support your treatment results.

While taking Numlo D 2.5 Tablet , some people may experience mild side effects like dizziness, lightheadedness, or mild ankle swelling. If you develop specific serious side effects, such as rapid heartbeats, severe muscle weakness, or signs of an allergic reaction, contact your doctor immediately.

Before starting Numlo D 2.5 Tablet , tell your doctor if you have a history of kidney disease, liver damage, gout, or severe dehydration. Do not take this medicine if you are unable to pass urine or if you have a known severe allergy to any of its components or sulphur-based drugs (sulfonamides).

Avoid drinking alcohol while taking Numlo D 2.5 Tablet , as it can excessively lower your blood pressure and cause severe dizziness. This medicine can also interact with other blood pressure drugs, lithium, and certain pain relievers, which can alter its effectiveness or increase side effects. If you are pregnant, planning to breastfeed, or an older adult, consult your doctor or pharmacist to ensure this medicine is safe for you.

Uses of Numlo D 2.5 Tablet

Numlo D 2.5 Tablet is used to treat high blood pressure (hypertension). The detailed uses of Numlo D 2.5 Tablet are as follows:

  • High blood pressure (hypertension): Numlo D 2.5 Tablet helps by relaxing the blood vessels and helping your body get rid of excess salt and water, which lowers your overall blood pressure.
  • Reducing cardiovascular risk: By maintaining a normal blood pressure level, this medicine lowers your risk of experiencing complications like strokes or heart attacks.

Key Benefits

Numlo D 2.5 Tablet helps manage high blood pressure effectively by combining two complementary medicines in a single tablet. With regular use, it supports stable blood pressure control, simplifies your treatment routine, and helps protect your heart, kidneys, and other vital organs from long-term damage.

  • Steady Blood Pressure Control: By combining two distinct actions in one tablet, Numlo D 2.5 Tablet provides consistent, round-the-clock blood pressure control. This helps keep your readings in a safe range throughout the day and night.
  • Convenience of a Combined Treatment: Instead of taking multiple separate pills, Numlo D 2.5 Tablet offers the convenience of a single daily tablet. This simplifies your daily routine and makes it much easier to stay on track with your treatment.
  • Long-Term Heart and Kidney Protection: Lowering your blood pressure helps protect your vital organs from strain. Over time, this decreases the likelihood of kidney failure, vision loss, and chronic heart failure, helping you maintain your long-term health and independence.

Directions for Use

  • Numlo D 2.5 Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Numlo D 2.5 Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Numlo D 2.5 Tablet Works

Numlo D 2.5 Tablet is a combination of two active medicines that work in different ways to lower your blood pressure. The first active ingredient is a calcium channel blocker. It works by relaxing and widening your blood vessels. When your blood vessels are relaxed, blood can flow through them much more easily, which immediately reduces the workload on your heart. The second active ingredient is a diuretic, often referred to as a 'water pill'. It works on your kidneys to help your body eliminate extra water and salt through your urine. Reducing the overall volume of fluid circulating in your bloodstream naturally lowers the pressure inside your blood vessels. Together, these two mechanisms provide a synergistic effect, lowering your blood pressure more effectively than either medicine could when used alone.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Numlo D 2.5 Tablet to avoid unpleasant side-effects.

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Pregnancy

Caution

Numlo D 2.5 Tablet is not recommended during pregnancy unless your doctor considers it essential. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

Numlo D 2.5 Tablet should not be used when breastfeeding unless clearly necessary. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Driving

Caution

Numlo D 2.5 Tablet may sometimes cause dizziness, nausea, tiredness or headache. Therefore, it is advised to drive only if you are alert after taking Numlo D 2.5 Tablet .

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Liver

Caution

Numlo D 2.5 Tablet to be taken with caution, especially if you have a history of liver diseases. Your doctor may adjust your dose depending on your current liver conditions.

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Kidney

Caution

Numlo D 2.5 Tablet to be taken with caution, especially if you have a history of kidney diseases. Your doctor may adjust your dose depending on your current kidney conditions.

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Children

Caution

Numlo D 2.5 Tablet to be taken with caution, especially if you are children below the age of 12. Your doctor may adjust your dose depending upon your age.

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Heart

Safe if prescribed

Numlo D 2.5 Tablet is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Numlo D 2.5 Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Numlo D 2.5 Tablet

If you accidentally take too much of Numlo D 2.5 Tablet , you may experience severe dizziness, fainting, a rapid heart rate, or extreme weakness. Seek immediate medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Limit sodium intake: Avoid high-sodium foods like processed meats, canned soups, and fast food. Reducing salt in your diet directly helps lower blood pressure.
  • Eat potassium-rich foods: Diuretics can sometimes lower your potassium levels. Talk to your doctor about incorporating foods like bananas, spinach, and sweet potatoes into your diet or if you need to monitor your potassium intake.
  • Stay properly hydrated: While this medicine helps remove excess water, severe dehydration can be dangerous. Drink a moderate, healthy amount of water daily unless your doctor advises otherwise.
  • Limit alcohol and quit smoking: Alcohol can dangerously lower your blood pressure when combined with Numlo D 2.5 Tablet , while smoking damages blood vessels and raises your cardiovascular risks.
  • Stand up slowly: To prevent dizziness or fainting when getting up from a sitting or lying position, stand up slowly and steady yourself for a moment.
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How Soon It Starts Working

  • The time required for Numlo D 2.5 Tablet to start to work: The time required for Numlo D 2.5 Tablet to start to work is 2 hours after administration.
  • The time for which the effects of Numlo D 2.5 Tablet last: The effect of Numlo D 2.5 Tablet lasts for 24 hours.

What if you forget to take Numlo D 2.5 Tablet

If you miss a dose of Numlo D 2.5 Tablet , take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Numlo D 2.5 Tablet tablets at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original packaging to protect them from light and moisture.

Drug Warnings

  • Monitor your blood pressure: Keep a daily log of your blood pressure readings at home and share it with your doctor during visits.
  • Avoid grapefruit products: Grapefruit and grapefruit juice can interact with this medicine, leading to higher levels of the medication in your blood and increasing the risk of side effects.
  • Protect your skin from the sun: This medicine can make your skin more sensitive to sunlight, increasing the risk of sunburns. Use sunscreen and wear protective clothing when outdoors.
  • Check other OTC medicines: Many over-the-counter medications, especially pain relievers like ibuprofen or cold medicines, can raise your blood pressure or interact with Numlo D 2.5 Tablet . Always consult your pharmacist before buying OTC remedies.
  • Schedule regular lab tests: Your doctor may order routine blood tests to check your kidney function and electrolyte levels (like potassium and sodium) while you are taking this medicine.

Drug-Drug Interactions

verifiedApollotooltip
  • Lithium: Taking Numlo D 2.5 Tablet with lithium can cause toxic levels of lithium to build up in your body.
  • Other blood pressure medications: Combining this medicine with other drugs that lower blood pressure can increase the risk of severely low blood pressure (hypotension).
  • NSAIDs (like ibuprofen or naproxen): These pain relievers can reduce the blood pressure-lowering effect of Numlo D 2.5 Tablet and increase the risk of kidney damage.
  • Potassium supplements: Taking potassium supplements or potassium-sparing water pills with this medicine requires close monitoring, as it can cause unsafe changes in your blood potassium levels.

Drug-Drug Interactions

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How does the drug interact with Numlo D 2.5 mg Tablet:
Taking Cisapride with S-Amlodipine and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe.

How to manage the interaction:
Combining Cisapride and Hydrochlorothiazide together is generally avoided as it can result in an interaction, it can be taken if advised by a doctor. However, if you experience dizziness, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Numlo D 2.5 mg Tablet:
Taking Dofetilide with S-Amlodipine and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe.

How to manage the interaction:
Combining Dofetilide with S-Amlodipine and Hydrochlorothiazide together is not recommended as it can result in an interaction, it can be taken if advised by a doctor. However, if you experience dizziness, shortness of breath, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Numlo D 2.5 mg Tablet:
Co-administration of Arsenic trioxide with S-Amlodipine and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe.

How to manage the interaction:
Taking Arsenic trioxide with S-Amlodipine and Hydrochlorothiazide together is avoided as it can result in an interaction, it can be taken if advised by a doctor. However, if you experience dizziness, fast heartbeats, muscle pain. consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Numlo D 2.5 mg Tablet:
Co-administration of Dronedarone with S-Amlodipine and Hydrochlorothiazide can increase the risk of severe irregular heart rhythm which can be severe.

How to manage the interaction:
Taking Dronedarone with Dronedarone together is avoided as it can result in an interaction, it can be taken if advised by a doctor. However, if you experience dizziness, fast or pounding heartbeats consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Numlo D 2.5 mg Tablet:
Co-administration of Mitotane with S-Amlodipine and Hydrochlorothiazide can reduce the blood levels of S-Amlodipine.

How to manage the interaction:
Co-administration of Mitotane with S-Amlodipine and Hydrochlorothiazide can lead to an interaction, but they can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Numlo D 2.5 mg Tablet:
Co-administration of Droperidol with S-Amlodipine and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe.

How to manage the interaction:
Taking Droperidol with S-Amlodipine and Hydrochlorothiazide together can result in an interaction, but they can be taken if advised by a doctor. However, consult the doctor immediately if you experience dizziness, fast heartbeats. Do not stop using any medications without a doctor's advice.
How does the drug interact with Numlo D 2.5 mg Tablet:
The combined use of Pimozide with S-Amlodipine and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe.

How to manage the interaction:
Taking Pimozide with S-Amlodipine and Hydrochlorothiazide together can result in an interaction, but it can be taken if advised by a doctor. However, consult the doctor immediately if you experience dizziness, fast or pounding heartbeats. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Numlo D 2.5 mg Tablet:
Coadministration of Aminolevulinic acid with S-Amlodipine and Hydrochlorothiazide can increase the risk or severity of developing a sunburn.

How to manage the interaction:
Although there is a possible interaction between S-Amlodipine and Hydrochlorothiazide, it can be taken if advised by a doctor. Avoid exposure of the eyes and skin to sunlight or bright indoor lights for 48 hours. Do not stop using any medications without a doctor's advice.
How does the drug interact with Numlo D 2.5 mg Tablet:
Co-administration of Ceritinib together with S-Amlodipine and Hydrochlorothiazide can slow the heart rate and increase the risk of an irregular heart rhythm which can be severe.

How to manage the interaction:
Co-administration of Ceritinib with S-Amlodipine and Hydrochlorothiazide can lead to an interaction, but they can be taken if advised by a doctor. However, if you experience dizziness, shortness of breath, rapid heartbeat contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Numlo D 2.5 mg Tablet:
Coadministration of Rifapentine with S-Amlodipine and Hydrochlorothiazide can reduce the blood levels of Amlodipine.

How to manage the interaction:
Co-administration of Rifapentine with S-Amlodipine and Hydrochlorothiazide can lead to an interaction, but they can be taken if advised by a doctor. Consult a doctor if you experience any unusual symptoms. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and grapefruit juice: May increase the absorption of this medicine, causing your blood pressure to drop too low and increasing side effects like swelling and dizziness.
  • Alcohol: Can worsen dizziness, lightheadedness, and the blood pressure-lowering effects of the medication.
     
AMLODIPINE-2.5MG+HYDROCHLOROTHIAZIDE-12.5MGPotassium rich foods, Calcium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-2.5MG+HYDROCHLOROTHIAZIDE-12.5MGPotassium rich foods, Calcium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt, Tofu Set With Calcium, Ragi, Seasame Seeds, Kale, Milk, Almonds, Bok Choy, Calcium-Fortified Soy Milk, Cheese

How to manage the interaction:
Consumption of Calcium-containing products with Numlo D 2.5 mg Tablet may decrease the effectiveness of Numlo D 2.5 mg Tablet. Also, grapefruit and its products may slightly increase plasma concentrations of Numlo D 2.5 mg Tablet. Avoid consuming Calcium-containing products, grapefruit and its products while being treated with Numlo D 2.5 mg Tablet.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Numlo D 2.5 Tablet is used to treat hypertension (high blood pressure).
Yes, Numlo D 2.5 Tablet may cause dizziness. It is advised to avoid driving or operating any heavy machinery while taking Numlo D 2.5 Tablet . In case you feel dizzy or light-headed, it is advised to rest for some time until you feel better.
Numlo D 2.5 Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are lifelong conditions, and one should not abruptly discontinue them without discussing it with a doctor.
No, it is a prescribed drug given by a physician to prevent specific medical conditions. Taking it on your own can cause unwanted side effects.
While taking Numlo D 2.5 Tablet , consult your doctor before adding any supplements to control blood pressure. Supplements can interact with the medication or increase side effects. Always consult your doctor to make an informed decision and ensure safe usage. They will help you determine the best course of action.
If you feel nauseous after taking Numlo D 2.5 Tablet , it's a common side effect that usually goes away with time. If it persists or bothers you, consult your doctor. In the meantime, take the tablet with food and stay hydrated to help manage nausea.
While taking Numlo D 2.5 Tablet , monitoring your vital signs and health indicators is essential. This includes keeping track of your blood pressure to ensure the medication is effectively controlling your hypertension, as well as regular blood tests to check your kidney function, potassium levels, and blood sugar levels, especially if you have diabetes. Additionally, monitoring your electrolyte levels, including potassium, sodium, and chloride, will help detect any imbalances.
The key active components present in Numlo D 2.5 Tablet are Amlodipine and Hydrochlorothiazide, which are antihypertensive medicines. Amlodipine, a calcium channel blocker, relaxes blood vessels, improving blood flow and reducing blood pressure. Hydrochlorothiazide, a diuretic, helps remove excess fluid from the body, reducing blood volume and blood pressure. These two medicines work together synergistically to effectively manage hypertension (high blood pressure).
Common side effects of Numlo D 2.5 Tablet may include glucose intolerance (low or high level of glucose), ankle swelling, sleepiness, headache (sense of heat in the face, ears, neck, and trunk), flushing, tiredness, nausea, decreased potassium level in the blood, Increased blood uric acid, and altered blood lipid level. Most of these side effects of Numlo D 2.5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.
Avoid or limit alcohol consumption while taking Numlo D 2.5 Tablet . Alcohol can increase the blood pressure-lowering effect of the medication, leading to dizziness or fainting. It can also increase the risk of dehydration and electrolyte imbalances. If you do drink alcohol, do so in moderation and consult your doctor for personalized advice.
Numlo D 2.5 Tablet is not recommended during pregnancy unless your doctor considers it essential. Your doctor will weigh the benefits and potential risks before prescribing it.
Numlo D 2.5 Tablet should not be used when breastfeeding unless clearly necessary. Your doctor will weigh the benefits and potential risks before prescribing it. Please consult your doctor.
Yes, you can take Numlo D 2.5 Tablet at night, but it is generally recommended to take it in the morning. Because this medicine contains a diuretic ('water pill'), taking it close to bedtime may cause you to wake up during the night to urinate. Talk to your doctor or pharmacist to find the best dosing schedule for you.
Mild ankle or foot swelling is a known side effect of this medicine. However, you should still report this to your doctor, especially if it worsens or is accompanied by breathing difficulties. Do not stop taking your medication without consulting your doctor.
You may begin to see a drop in your blood pressure within a few days of starting Numlo D 2.5 Tablet , but it can take up to 2 to 4 weeks to reach its full therapeutic effect. Continue taking the medicine daily even if you feel well. Talk to your doctor if you do not see an improvement.
Caffeine can temporarily raise your blood pressure, which may counteract the effects of Numlo D 2.5 Tablet . It is usually safe to consume moderate amounts of caffeine, but you should discuss your daily caffeine intake with your doctor.
Numlo D 2.5 Tablet does not typically cause significant weight gain. If you notice a sudden, rapid increase in weight, it may be due to fluid retention (oedema), which is a possible side effect. If this happens, talk to your doctor right away.
This medicine can make your skin more sensitive to sunlight, making you sunburn more easily. You do not need to avoid the sun entirely, but you should apply high-SPF sunscreen, wear protective clothing, and avoid tanning beds. Talk to your doctor if you experience a severe sunburn or skin rash.
You should avoid taking ibuprofen or other nonsteroidal anti-inflammatory drugs (NSAIDs) regularly without consulting your doctor. NSAIDs can decrease the effectiveness of Numlo D 2.5 Tablet and increase your risk of kidney damage. Talk to your doctor or pharmacist about safer pain relief alternatives.
Stopping Numlo D 2.5 Tablet suddenly can cause your blood pressure to rise rapidly, increasing your risk of serious heart complications or stroke. If you need to stop this medication, your doctor will guide you on how to do so safely. Always talk to your doctor before making any changes.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - NUM0070
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