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Numlo D 2.5 Tablet is used to treat hypertension (high blood pressure). It contains Amlodipine and Hydrochlorothiazide, which relax and widen blood vessels. Also, it helps to remove extra water and certain electrolytes from the body through urine. Thus, it lowers high blood pressure and reduces the chances of future heart attack and stroke. It may cause side effects such as glucose intolerance (low or high level of glucose), ankle swelling, sleepiness, headache, (sense of heat in the face, ears, neck, and trunk), flushing, tiredness, nausea, decreased potassium level in the blood, increased blood uric acid, and altered blood lipid level.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Numlo D 2.5 Tablet

Numlo D 2.5 Tablet belongs to the class of antihypertensives and is primarily used to treat hypertension (high blood pressure). Hypertension, or high blood pressure, is a chronic condition in which the force exerted by the blood against the arterial wall is high. As a result, it leads to heart disease, irregular heartbeat, and other complications.

Numlo D 2.5 Tablet is a combination of two medicines, including Amlodipine and Hydrochlorothiazide. Amlodipine is a calcium channel blocker that relaxes and widens blood vessels. Hydrochlorothiazide is a diuretic that removes excess water and certain electrolytes from the body through urine. Numlo D 2.5 Tablet helps lower high blood pressure, thereby reducing the risk of future heart attack and stroke.

You may experience glucose intolerance (low or high level of glucose), ankle swelling, sleepiness, headache, (sense of heat in the face, ears, neck, and trunk), flushing, tiredness, nausea, decreased potassium level in the blood, increased blood uric acid, and altered blood lipid level. Most of the side effects of Numlo D 2.5 Tablet do not require medical attention and resolve gradually over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have had an allergic reaction to Numlo D 2.5 Tablet , have liver disease, kidney disease, heart failure, a heart valve problem, or have a history of a heart attack. Immediately contact your doctor if you are pregnant or are planning to get pregnant, or are breastfeeding.

Do not stop taking Numlo D 2.5 Tablet without your doctor's advice. If you stop taking Numlo D 2.5 Tablet suddenly, it may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will gradually lower your dose to help prevent these symptoms.

Uses of Numlo D 2.5 Tablet

Numlo D 2.5 Tablet used in the treatment of Hypertension. The detailed uses of Numlo D 2.5 Tablet are as follows:

  • Management of Hypertension: Numlo D 2.5 Tablet helps to control high blood pressure by relaxing blood vessels and enhancing blood flow.
  • Reducing Cardiovascular Risk: By controlling hypertension, Numlo D 2.5 Tablet reduces the risk of cardiovascular complications such as heart attacks and strokes.

Key Benefits

  • Helps lower high blood pressure (hypertension) effectively.
  • Reduces the risk of heart attack, stroke, and kidney problems caused by prolonged high blood pressure.
  • Amlodipine relaxes and widens blood vessels, improving blood flow.
  • Hydrochlorothiazide helps the body eliminate excess salt and water through urine, reducing fluid retention.
  • Decreases strain on the heart and arteries.
  • Helps control swelling (oedema) caused by fluid buildup in the body.
  • Provides a combined action that enhances blood pressure control compared to single-drug therapy.
  • Supports long-term cardiovascular health when taken regularly as prescribed.

Directions for Use

  • Numlo D 2.5 Tablet can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Numlo D 2.5 Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Numlo D 2.5 Tablet Works

Numlo D 2.5 Tablet is a combination of two antihypertensive medicines, Amlodipine and Hydrochlorothiazide. Amlodipine is a calcium channel blocker that relaxes and widens blood vessels. Hydrochlorothiazide is a diuretic that removes excess water and certain electrolytes from the body through urine. Numlo D 2.5 Tablet helps lower high blood pressure, thereby reducing the risk of future heart attack and stroke. Over time, it also relaxes blood vessels and enhances blood flow.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Numlo D 2.5 Tablet to avoid unpleasant side-effects.

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Pregnancy

Caution

Numlo D 2.5 Tablet is not recommended during pregnancy unless your doctor considers it essential. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

Numlo D 2.5 Tablet should not be used when breastfeeding unless clearly necessary. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Driving

Caution

Numlo D 2.5 Tablet may sometimes cause dizziness, nausea, tiredness or headache. Therefore, it is advised to drive only if you are alert after taking Numlo D 2.5 Tablet .

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Liver

Caution

Numlo D 2.5 Tablet to be taken with caution, especially if you have a history of liver diseases. Your doctor may adjust your dose depending on your current liver conditions.

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Kidney

Caution

Numlo D 2.5 Tablet to be taken with caution, especially if you have a history of kidney diseases. Your doctor may adjust your dose depending on your current kidney conditions.

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Children

Caution

Numlo D 2.5 Tablet to be taken with caution, especially if you are children below the age of 12. Your doctor may adjust your dose depending upon your age.

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Heart

Safe if prescribed

Numlo D 2.5 Tablet is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Numlo D 2.5 Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Numlo D 2.5 Tablet

Do not take more than the prescribed dose of Numlo D 2.5 Tablet as it may cause overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days. Doing this can help you lower your high blood pressure by about 5 mmHg.
  • Avoid stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Option for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Limit your intake of sodium chloride (table salt) to 2300 mg per day or less; 1500 mg or less is ideal for most adults.
  • Try to include heart-healthy omega-3 fatty acids-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to help lower your elevated blood pressure.
  • Monitor your blood pressure daily, and if there is excessive fluctuation, contact your doctor immediately.

Have a query?

How Soon It Starts Working

  • The time required for Numlo D 2.5 Tablet to start to work: The time required for Numlo D 2.5 Tablet to start to work is 2 hours after administration.
  • The time for which the effects of Numlo D 2.5 Tablet last: The effect of Numlo D 2.5 Tablet lasts for 24 hours.

What if you forget to take Numlo D 2.5 Tablet

If you miss a dose of Numlo D 2.5 Tablet , take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not take a double dose to make up for the missed dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Numlo D 2.5 Tablet should be used with extreme caution in patients with liver, kidney, cardiovascular diseases, and diabetic patients.
  • Use only if the potential benefit justifies the potential risk.
  • Immediately contact your doctor if you are pregnant or are planning to get pregnant, are breastfeeding.
  • Do not stop taking Numlo D 2.5 Tablet without your doctor's advice. If you stop taking Numlo D 2.5 Tablet suddenly, it may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack.

Drug-Drug Interactions

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Drug-Drug Interaction: Numlo D 2.5 Tablet may have an interaction with medicines used to treat mood disorders such as (lithium), medicines used to treat heart disorders such as (digoxin), antidiabetic medicines such as (metformin), medicines used to treat erectile dysfunction such as (sildenafil), medicines used to lower cholesterol levels such as (simvastatin), ACE-inhibitor (such as enalapril, lisinopril, ramipril), and medicines used for immunosuppression such as (cyclosporine).

Drug-Food Interaction: Avoid foods with high fat or cholesterol. Avoid too much salt in your diet like pickles, extra salt on salad, etc. You are recommended not to consume alcohol along with Numlo D 2.5 Tablet to avoid unpleasant side effects.

Drug-Disease Interaction: Numlo D 2.5 Tablet should not be given to people with cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), liver disease, kidney disease, or heart failure, low serum potassium (hypokalemia), patients with nil urine output (anuria).

Drug-Drug Interactions

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How does the drug interact with Numlo D 2.5 mg Tablet:
Taking Dofetilide with S-Amlodipine and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe.

How to manage the interaction:
Combining Dofetilide with S-Amlodipine and Hydrochlorothiazide together is not recommended as it can result in an interaction, it can be taken if advised by a doctor. However, if you experience dizziness, shortness of breath, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Numlo D 2.5 mg Tablet:
Taking Cisapride with S-Amlodipine and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe.

How to manage the interaction:
Combining Cisapride and Hydrochlorothiazide together is generally avoided as it can result in an interaction, it can be taken if advised by a doctor. However, if you experience dizziness, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Numlo D 2.5 mg Tablet:
Co-administration of Arsenic trioxide with S-Amlodipine and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe.

How to manage the interaction:
Taking Arsenic trioxide with S-Amlodipine and Hydrochlorothiazide together is avoided as it can result in an interaction, it can be taken if advised by a doctor. However, if you experience dizziness, fast heartbeats, muscle pain. consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Numlo D 2.5 mg Tablet:
Taking carbamazepine with S-Amlodipine and Hydrochlorothiazide together may reduce the blood levels of S-Amlodipine, which could reduce its treatment outcomes.

How to manage the interaction:
Although taking Carbamazepine with S-Amlodipine and Hydrochlorothiazide together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Numlo D 2.5 mg Tablet:
Coadministration of S-Amlodipine and Hydrochlorothiazide with Itraconazole may significantly raise the blood levels and effects of Amlodipine.

How to manage the interaction:
Coadministration of S-Amlodipine and Hydrochlorothiazide with Itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Numlo D 2.5 mg Tablet:
Coadministration of Lithium with S-Amlodipine and Hydrochlorothiazide can increase the effects of lithium.

How to manage the interaction:
Taking Lithium with S-Amlodipine and Hydrochlorothiazide together can result in an interaction, but it can be taken if advised by a doctor. However, if you experience diarrhea, shaking of hands and legs, thirst, increased urination consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Numlo D 2.5 mg Tablet:
Coadministration of Aminolevulinic acid with S-Amlodipine and Hydrochlorothiazide can increase the risk or severity of developing a sunburn.

How to manage the interaction:
Although there is a possible interaction between S-Amlodipine and Hydrochlorothiazide, it can be taken if advised by a doctor. Avoid exposure of the eyes and skin to sunlight or bright indoor lights for 48 hours. Do not stop using any medications without a doctor's advice.
How does the drug interact with Numlo D 2.5 mg Tablet:
Co-administration of Mitotane with S-Amlodipine and Hydrochlorothiazide can reduce the blood levels of S-Amlodipine.

How to manage the interaction:
Co-administration of Mitotane with S-Amlodipine and Hydrochlorothiazide can lead to an interaction, but they can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Numlo D 2.5 mg Tablet:
Co-administration of Dolasetron with S-Amlodipine and Hydrochlorothiazide can affect the rhythm of your heart which can be severe.

How to manage the interaction:
Taking Dolasetron with S-Amlodipine and Hydrochlorothiazide together is avoided as it can result in an interaction, it can be taken if advised by a doctor. However, if you experience irregular heartbeat, chest tightness consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Numlo D 2.5 mg Tablet:
Co-administration of Simvastatin and S-Amlodipine and Hydrochlorothiazide together can increase the blood levels of simvastatin and increase the risk of side effects.

How to manage the interaction:
Taking of Simvastatin with S-Amlodipine and Hydrochlorothiazide can lead to interaction, but they can be taken if advised by a doctor. However, if you experience muscle pain, dark-coloured urine, yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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AMLODIPINE-2.5MG+HYDROCHLOROTHIAZIDE-12.5MGPotassium rich foods, Calcium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-2.5MG+HYDROCHLOROTHIAZIDE-12.5MGPotassium rich foods, Calcium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt, Tofu Set With Calcium, Ragi, Seasame Seeds, Kale, Milk, Almonds, Bok Choy, Calcium-Fortified Soy Milk, Cheese

How to manage the interaction:
Consumption of Calcium-containing products with Numlo D 2.5 mg Tablet may decrease the effectiveness of Numlo D 2.5 mg Tablet. Also, grapefruit and its products may slightly increase plasma concentrations of Numlo D 2.5 mg Tablet. Avoid consuming Calcium-containing products, grapefruit and its products while being treated with Numlo D 2.5 mg Tablet.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Numlo D 2.5 Tablet is used to treat hypertension (high blood pressure).

No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending on your current blood pressure readings, your doctor may lower your medication dosage and not recommend discontinuing it.

If you forget to take the Numlo D 2.5 Tablet , take it as soon as you remember, then continue taking it at the usual times. Do not take a double dose to make up for a forgotten dose.

Yes, Numlo D 2.5 Tablet may cause dizziness. It is advised to avoid driving or operating any heavy machinery while taking Numlo D 2.5 Tablet . In case you feel dizzy or light-headed, it is advised to rest for some time until you feel better.

Numlo D 2.5 Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are lifelong conditions, and one should not abruptly discontinue them without discussing it with a doctor.

No, it is a prescribed drug given by a physician to prevent specific medical conditions. Taking it on your own can cause unwanted side effects.

Take Numlo D 2.5 Tablet once a day, at the same time each day, with or without food. Usually, take it in the morning to help control blood pressure throughout the day. Remember to follow your doctor's instructions and take it at the same time daily to make it a habit.

While taking Numlo D 2.5 Tablet , consult your doctor before adding any supplements to control blood pressure. Supplements can interact with the medication or increase side effects. Always consult your doctor to make an informed decision and ensure safe usage. They will help you determine the best course of action.

If you feel nauseous after taking Numlo D 2.5 Tablet , it's a common side effect that usually goes away with time. If it persists or bothers you, consult your doctor. In the meantime, take the tablet with food and stay hydrated to help manage nausea.

While taking Numlo D 2.5 Tablet , monitoring your vital signs and health indicators is essential. This includes keeping track of your blood pressure to ensure the medication is effectively controlling your hypertension, as well as regular blood tests to check your kidney function, potassium levels, and blood sugar levels, especially if you have diabetes. Additionally, monitoring your electrolyte levels, including potassium, sodium, and chloride, will help detect any imbalances.

Try using a pill box to organize your medicines or set reminders on your phone or calendar. You can also take your medications at the same time each day or ask a family member or friend to remind you. Additionally, you can place sticky notes in visible spots or explore medication reminder apps to help you stay on track. Choose the method that works best for you.

The key active components present in Numlo D 2.5 Tablet are Amlodipine and Hydrochlorothiazide, which are antihypertensive medicines. Amlodipine, a calcium channel blocker, relaxes blood vessels, improving blood flow and reducing blood pressure. Hydrochlorothiazide, a diuretic, helps remove excess fluid from the body, reducing blood volume and blood pressure. These two medicines work together synergistically to effectively manage hypertension (high blood pressure).

Common side effects of Numlo D 2.5 Tablet may include glucose intolerance (low or high level of glucose), ankle swelling, sleepiness, headache (sense of heat in the face, ears, neck, and trunk), flushing, tiredness, nausea, decreased potassium level in the blood, Increased blood uric acid, and altered blood lipid level. Most of these side effects of Numlo D 2.5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

Avoid or limit alcohol consumption while taking Numlo D 2.5 Tablet . Alcohol can increase the blood pressure-lowering effect of the medication, leading to dizziness or fainting. It can also increase the risk of dehydration and electrolyte imbalances. If you do drink alcohol, do so in moderation and consult your doctor for personalized advice.

Numlo D 2.5 Tablet is not recommended during pregnancy unless your doctor considers it essential. Your doctor will weigh the benefits and potential risks before prescribing it.

Numlo D 2.5 Tablet should not be used when breastfeeding unless clearly necessary. Your doctor will weigh the benefits and potential risks before prescribing it. Please consult your doctor.

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Author Details

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Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - NUM0070
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