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Numlo-D Tablet is used for the treatment of hypertension (high blood pressure). It contains S-Amlodipine and Hydrochlorothiazide, which works by relaxing and widening the blood vessels. Also, it helps to remove extra water and certain electrolytes from the body through urine. Thus, it lowers high blood pressure and reduces the chances of future heart attack and stroke. It may cause side effects such as ankle swelling, sleepiness, headache (sense of heat in the face, ears, neck, and trunk), flushing, tiredness, nausea, and decreased potassium level in the blood. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Numlo-D Tablet

Numlo-D Tablet belongs to the class of anti-hypertensives and is primarily taken for the treatment of hypertension (high blood pressure). Hypertension or high blood pressure is a chronic condition in which the force exerted by the blood against the artery wall is high. As a result, it leads to heart disease, irregular heartbeat, and other complications. Oedema may occur in cases of high blood pressure where fluids of the body get trapped in the tissues of the hands, arms, feet, ankles, and legs, leading to swelling. 

Numlo-D Tablet is a combination of two medicines: S-Amlodipine and Hydrochlorothiazide, which are antihypertensive medicines. S-Amlodipine(Levamlodipine) is a calcium channel blocker that works by relaxing and widening blood vessels. Hydrochlorothiazide is a diuretic, and its function is to remove extra water and certain electrolytes from the body through urine. Numlo-D Tablet helps to lower high blood pressure, thus reducing the chances of future heart attack and stroke. Over time, it also relaxes vessels of blood and enhances the flow of blood.

Take Numlo-D Tablet as prescribed by your doctor. You are advised to take Numlo-D Tablet as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience ankle swelling, sleepiness, headache (sense of heat in the face, ears, neck, and trunk), flushing, tiredness, nausea, and decreased potassium levels in the blood. Most of these side effects of Numlo-D Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have had an allergic reaction to Numlo-D Tablet , have liver disease, kidney disease, heart failure, a heart valve problem, or a history of a heart attack. Immediately contact your doctor if you are pregnant, are planning to get pregnant or are breastfeeding. Do not stop taking $ name without your doctor's advice. Sudden Stopping Numlo-D Tablet may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over a period to help prevent these symptoms.

Uses of Numlo-D Tablet

Numlo-D Tablet is used in the treatment of Hypertension. The detailed uses of Numlo-D Tablet are as follows:

  • Treats Hypertension (High Blood Pressure): Numlo-D Tablet helps lower elevated blood pressure and reduce the risk of heart attack and stroke.
  • Reduces Fluid Retention (Edema): Numlo-D Tablet helps the body eliminate excess water and salt through urine.
  • Supports Heart Health: Numlo-D Tablet eases the workload on the heart and helps prevent complications like heart failure.
  • Prevents Future Cardiovascular Events: Numlo-D Tablet helps reduce the chances of stroke, heart attack, and other blood pressure-related issues.

Key Benefits

When you take Numlo-D Tablet , it works by relaxing the blood vessels and making the heart more efficient at pumping blood throughout the body. It helps to lower high blood pressure, thus reducing the chances of future heart attacks and strokes. It also removes extra water and certain electrolytes from the body through urine.

Directions for Use

  • Take Numlo-D Tablet with or without food or as advised by a doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Numlo-D Tablet Works

Numlo-D Tablet is a combination of two medicines: S-Amlodipine and Hydrochlorothiazide, which are antihypertensive medicines. S-Amlodipine(Levamlodipine) is a calcium channel blocker that works by relaxing and widening blood vessels. Hydrochlorothiazide is a diuretic, and its function is to remove extra water and certain electrolytes from the body through urine. Numlo-D Tablet helps to lower high blood pressure, thus reducing the chances of future heart attack and stroke.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Numlo-D Tablet to avoid unpleasant side-effects.

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Pregnancy

Caution

Numlo-D Tablet is not recommended during pregnancy unless your doctor considers it essential. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

Numlo-D Tablet should not be used when breastfeeding unless clearly necessary. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Driving

Unsafe

It is advised to drive with caution after taking Numlo-D Tablet as it usually causes drowsiness and affects the driving ability.

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Liver

Caution

Numlo-D Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending upon your current liver conditions.

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Kidney

Caution

Numlo-D Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Your doctor may adjust your dose depending upon your current kidney conditions

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Children

Caution

Numlo-D Tablet to be taken with caution, especially if you are children below the age of 12. Your doctor may adjust your dose depending upon your age.

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Heart

Safe if prescribed

Numlo-D Tablet is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Numlo-D Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Numlo-D Tablet

Do not take more than the prescribed dose of Numlo-D Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.
  • Regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week, can help lower your raised blood pressure by about 5 mm of Hg.
  • Avoid stress, as it can raise your blood pressure. To cope with stress, try to enjoy and spend time with your loved ones and practice mindfulness techniques.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Option for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Limiting sodium chloride (table salt) intake to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. Low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil can help lower your elevated blood pressure.
  • Monitor your blood pressure daily, and if there is too much fluctuation, immediately contact your doctor.

Have a query?

How Soon It Starts Working

The time required for Numlo-D Tablet to start to work: The time required for Numlo-D Tablet to show its action is unknown. The time for which the effects of Numlo-D Tablet last: The duration of action for Numlo-D Tablet is clinically unknown.

What if you forget to take Numlo-D Tablet

If you miss a dose of Numlo-D Tablet , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Numlo-D Tablet should be used with extreme caution in patients with liver, kidney, and cardiovascular diseases. Use only if the potential benefit justifies the potential risk. Immediately contact your doctor if you are pregnant, are planning to get pregnant or are breastfeeding. Do not stop taking $ name without your doctor's advice. Sudden Stopping Numlo-D Tablet may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Please consult your doctor. Your doctor will weigh the benefits and any potential risks before prescribing it to you. 

Drug-Drug Interactions

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Drug-drug interaction: This medicine may have an interaction with medicines used to treat mood disorders, such as (lithium), medicines used to treat heart disorders, such as (digoxin); antidiabetic medicines, such as (metformin); medicines used to treat erectile dysfunction, such as (sildenafil), medicines used to lower cholesterol levels such as (simvastatin), ACE-inhibitor (such as enalapril, lisinopril, ramipril), and medicines used for immunosuppression such as (cyclosporine).

Drug-Food Interaction: Avoid foods with high fat or cholesterol. Avoid too much salt in your diet, like pickles and extra salt on salad. It is recommended not to consume alcohol along with Numlo-D Tablet to avoid unpleasant side effects.

Drug-Disease Interaction: Numlo-D Tablet should not be given to people with cardiogenic shock (when the heart fails to pump the required blood to the body), heart valve problems (stenosis), low blood pressure (hypotension), liver disease, kidney disease, or heart failure, low serum potassium (hypokalemia), or patients with nil urine output (anuria).

Drug-Drug Interactions

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How does the drug interact with Numlo-D Tablet:
Taking Cisapride with S-Amlodipine and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe.

How to manage the interaction:
Combining Cisapride and Hydrochlorothiazide together is generally avoided as it can result in an interaction, it can be taken if advised by a doctor. However, if you experience dizziness, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Numlo-D Tablet:
Taking Dofetilide with S-Amlodipine and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe.

How to manage the interaction:
Combining Dofetilide with S-Amlodipine and Hydrochlorothiazide together is not recommended as it can result in an interaction, it can be taken if advised by a doctor. However, if you experience dizziness, shortness of breath, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Numlo-D Tablet:
Coadministration of Amiodarone together with S-Amlodipine and Hydrochlorothiazide may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Amiodarone with S-Amlodipine and Hydrochlorothiazide interact, they can be used if prescribed by a doctor. If you experience dizziness, shortness of breath, or rapid heartbeat get medical attention. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Numlo-D Tablet:
Co-administration of Ceritinib together with S-Amlodipine and Hydrochlorothiazide can slow the heart rate and increase the risk of an irregular heart rhythm which can be severe.

How to manage the interaction:
Co-administration of Ceritinib with S-Amlodipine and Hydrochlorothiazide can lead to an interaction, but they can be taken if advised by a doctor. However, if you experience dizziness, shortness of breath, rapid heartbeat contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Numlo-D Tablet:
Taking Ziprasidone with S-Amlodipine and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe.

How to manage the interaction:
Taking Ziprasidone with S-Amlodipine and Hydrochlorothiazide is avoided as it can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, shortness of breath, fast heartbeats. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Numlo-D Tablet:
Taking carbamazepine with S-Amlodipine and Hydrochlorothiazide together may reduce the blood levels of S-Amlodipine, which could reduce its treatment outcomes.

How to manage the interaction:
Although taking Carbamazepine with S-Amlodipine and Hydrochlorothiazide together can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Numlo-D Tablet:
Co-administration of Simvastatin and S-Amlodipine and Hydrochlorothiazide together can increase the blood levels of simvastatin and increase the risk of side effects.

How to manage the interaction:
Taking of Simvastatin with S-Amlodipine and Hydrochlorothiazide can lead to interaction, but they can be taken if advised by a doctor. However, if you experience muscle pain, dark-coloured urine, yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Numlo-D Tablet:
Co-administration of Droperidol with S-Amlodipine and Hydrochlorothiazide can increase the risk of an irregular heart rhythm which can be severe.

How to manage the interaction:
Taking Droperidol with S-Amlodipine and Hydrochlorothiazide together can result in an interaction, but they can be taken if advised by a doctor. However, consult the doctor immediately if you experience dizziness, fast heartbeats. Do not stop using any medications without a doctor's advice.
How does the drug interact with Numlo-D Tablet:
Coadministration of S-Amlodipine and Hydrochlorothiazide with Itraconazole may significantly raise the blood levels and effects of Amlodipine.

How to manage the interaction:
Coadministration of S-Amlodipine and Hydrochlorothiazide with Itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Numlo-D Tablet:
Co-administration of Mitotane with S-Amlodipine and Hydrochlorothiazide can reduce the blood levels of S-Amlodipine.

How to manage the interaction:
Co-administration of Mitotane with S-Amlodipine and Hydrochlorothiazide can lead to an interaction, but they can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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HYDROCHLOROTHIAZIDE-12.5MG+S AMLODIPINE-2.5MGPotassium rich foods, Calcium rich foods
Moderate

Drug-Food Interactions

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HYDROCHLOROTHIAZIDE-12.5MG+S AMLODIPINE-2.5MGPotassium rich foods, Calcium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt, Tofu Set With Calcium, Ragi, Seasame Seeds, Kale, Milk, Almonds, Bok Choy, Calcium-Fortified Soy Milk, Cheese

How to manage the interaction:
Consumption of Calcium-containing products with Numlo-D Tablet may decrease the effectiveness of Numlo-D Tablet. Also, grapefruit and its products may slightly increase plasma concentrations of Numlo-D Tablet. Avoid consuming Calcium-containing products, grapefruit and its products while being treated with Numlo-D Tablet.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Numlo-D Tablet is used to treat high blood pressure. It works by relaxing the blood vessels, improving blood flow and lowering fluid retention.

No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.

In case, If you forget to take Numlo-D Tablet at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.

Numlo-D Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor.

No, it is a prescribed drug, given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side-effects.

Yes, Numlo-D Tablet may cause swelling of ankle and feet, it is advised to not sit for a long time, and keep the feet up when sitting or lying down.

Numlo-D Tablet should be taken in the morning with or without food as prescribed by the doctor, as it contains chlorothiazide, a diuretic that increases urination. So, morning doses help to prevent frequent urination at night, which could disturb your sleep.

You can take other supplements for controlling blood pressure along with Numlo-D Tablet only if prescribed by the doctor. Consult the doctor before taking Numlo-D Tablet with supplements.

Nausea is a common side effect caused by Numlo-D Tablet . If you experience nausea drink ginger or peppermint tea, stay hydrated, eat small, frequent meals and get fresh air.

Regular monitoring of heart rate, blood pressure, breathing and oxygen levels and electrolytes are advised in order to ensure Numlo-D Tablet is working effectively and to detect any potential side effects early while taking Numlo-D Tablet .

If you are having trouble remembering to take Numlo-D Tablet , link your medication doses with daily activity, use alarms to notify the time, use a pill organiser and create a routine by taking your medication at the same time every day.

The side effects of Numlo-D Tablet include ankle swelling, oedema, tiredness, fatigue nausea, sleepiness, headache (sense of heat in the face, ears, neck, and trunk), flushing, and decreased potassium levels in the blood. Consult the doctor if any of these side effects persist or worsen.

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Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - NUM0002
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