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Botropase Injection 1 ml is a haemostatic medicine used to prevent bleeding in conditions such as oral bleeding, pulmonary bleeding, traumatic bleeding, postoperative bleeding, and other external and internal haemorrhages. This medicine promotes blood clotting and coagulation, thereby effectively controlling bleeding. Common side effects include pain, swelling, and redness at the site of injection.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Juggat Pharma Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Botropase Injection 1 ml

Botropase Injection 1 ml is a prescription medicine given to help stop and prevent excessive bleeding. It is commonly used to manage severe blood loss during or after surgical procedures, dental operations, or physical injuries. By helping your blood clot more efficiently, it supports your body’s natural healing process.

Because this medicine is typically given in a clinical setting around the time of a medical procedure, your healthcare provider will decide how often you need it. Since it is given as an injection, you do not need to worry about taking it with food. To support your recovery, your doctor may suggest eating a balanced diet with nutrient-rich foods that naturally support healthy blood vessels and circulation.

While most people tolerate this medicine well, some may experience mild side effects, such as pain or swelling where the medicine was injected. If you experience any severe reactions, such as sudden chest pain or difficulty breathing, you must seek medical help immediately. Always discuss any unexpected symptoms with your doctor or pharmacist.

Do not use if you are allergic to snake venom-derived products, have active thrombosis (blood clots in the veins or arteries) or an ongoing thromboembolic disorder, or active disseminated intravascular coagulation (DIC), unless your doctor specifically advises its use.

If you are pregnant or breastfeeding, have children, are an older adult, or have kidney or liver disease, this medicine should be used only under medical supervision. Your doctor will determine the appropriate dose and monitor you as needed.

Uses of Botropase Injection 1 ml

Your doctor may recommend this medicine to help manage the following conditions:

  • Surgical bleeding: Botropase Injection 1 ml helps control active bleeding during and after various types of surgeries, making procedures safer and cleaner.
  • Dental bleeding: It is used to stop persistent bleeding after tooth extractions or oral surgeries.
  • Traumatic bleeding: It helps reduce blood loss from deep cuts, accidental wounds, or severe physical injuries.
  • Internal bleeding: It assists in managing bleeding inside body cavities, such as the stomach or lungs, under close medical supervision.

Key Benefits

When taken consistently as directed, this medicine may provide the following physiological benefits:

  • Controls bleeding: It acts quickly at the source of the bleed to minimise blood loss during critical procedures.
  • Supports tissue healing: Preventing blood from collecting under the skin (hematomas), it helps your tissues heal more cleanly and comfortably.
  • Improves surgical outcomes: It gives your surgical team a clearer view during operations, reducing the risk of complications from excessive bleeding.

Directions for Use

  • Follow your doctor's recommendations on the dosage and timing of this medication to achieve optimal results.
  • Botropase Injection 1 ml will be administered by a healthcare professional.
  • Do not self-administer.

How Botropase Injection 1 ml Works

Botropase Injection 1 ml contains enzymes that help your body form blood clots. One enzyme works in a way similar to your body's natural clotting proteins to convert fibrinogen into fibrin, while another helps speed up the body's clotting process. Together, these actions help form a clot more quickly to control bleeding during injury or surgery.
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Alcohol

Caution

It is not known whether it is safe to consume alcohol with Botropase Injection 1 ml. Please consult your doctor.

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Pregnancy

Caution

There is limited information on the effects of Botropase Injection 1 ml on pregnancy. Please consult your doctor.

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Breast Feeding

Caution

There is limited information on the effects of Botropase Injection 1 ml in nursing mothers. Please consult your doctor.

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Driving

Caution

There is limited information on the effects of Botropase Injection 1 ml on driving abilities. Please consult your doctor.

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Liver

Caution

There is limited information on the effects of Botropase Injection 1 ml on the liver. Please consult your doctor.

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Kidney

Caution

There is limited information on the effects of Botropase Injection 1 ml on the kidney. Please consult your doctor.

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Children

Caution

Botropase Injection 1 ml should be used with caution in children. Please consult your doctor.

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Heart

Caution

Limited information was available regarding the use of Botropase Injection 1 ml in patients with heart problems. Please consult your doctor.

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Geriatrics

Caution

Botropase Injection 1 ml should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of Botropase Injection 1 ml

If you suspect that you or someone else has received too much of this medicine, seek emergency medical care immediately. An overdose may increase the risk of abnormal blood clots forming in your blood vessels.

Diet & Lifestyle Advise

  • Avoid injuries: Stay away from activities with a high risk of falls, cuts, or physical injury while recovering.
  • Prevent bleeding: Use a soft-bristled toothbrush and shave carefully to reduce the risk of bleeding from your gums or skin.
  • Avoid certain painkillers: Do not take aspirin, ibuprofen, naproxen, or other anti-inflammatory pain relievers unless advised by your doctor, as they may increase the risk of bleeding.
  • Attend follow-up visits: Keep all follow-up appointments so your healthcare team can monitor your healing and blood clotting.
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How Soon It Starts Working

The time required for Botropase Injection 1 ml to start to work: The effect of Botropase Injection 1 ml is observed within 10 to 30 minutes of administration. The time for which the effects of Botropase Injection 1 ml last: Botropase Injection 1 ml effect lasts for 4 to 6 hours.

What if you forget to take Botropase Injection 1 ml

Because this medicine is typically injected by a healthcare professional in a clinic, it is unlikely that you will miss a dose. However, if you are using it at home and miss a scheduled injection, contact your doctor or pharmacist immediately for guidance. Do not inject a double dose to make up for a missed one.

Storage

•Follow the manufacturer's specific storage instructions — some products require refrigeration at 2°C to 8°C while others may be stored at room temperature. •Keep injection vials in original outer carton to protect them from direct light and moisture.

Drug Warnings

  • Inspect before use: Do not use the medicine if the liquid is cloudy, discoloured, or contains floating particles.
  • Use sterile equipment: Use a new sterile needle and syringe for each injection and dispose of them in a puncture-proof sharps container.
  • Rotate injection sites: If self-injecting, use a different injection site each time to help prevent skin irritation.
  • Inform your healthcare provider: Tell your dentist or surgeon that you have recently received medicine before any procedure.
  • Monitor the injection site: Contact your doctor if you notice increasing redness, warmth, swelling, or fluid leaking from the injection site.
  • Use in Children: They may be used in children when clinically necessary, but only under the supervision of a doctor. The dose is determined based on the child's age, weight, and medical condition.
  • Monitoring during treatment: Your doctor may monitor your clinical response and, when appropriate, perform blood clotting tests to assess your condition and guide treatment, especially during or after surgery or if bleeding persists.
  • Allergic to venom: Do not receive if you are allergic to snake venom-derived products or any ingredient in this medicine.
  • When to Contact Your Doctor: If bleeding does not stop or worsens after treatment, seek medical attention immediately. Your doctor may need to identify the cause of the bleeding or recommend additional treatment.

verifiedApollotooltip
  • Blood thinners (anticoagulants): Medicines such as warfarin, heparin, or apixaban may reduce the effectiveness of Botropase Injection 1 ml. They may also independently increase the risk of bleeding, so your doctor may recommend closer monitoring or adjust your treatment if both are used together.
  • Fibrinolytic medicines (e.g., streptokinase, alteplase): These medicines dissolve blood clots and may reduce the effectiveness of Botropase Injection 1 ml. Tell your doctor if you are receiving these treatments.

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  • Alcohol: Avoid drinking alcohol during treatment, as it can impair your liver's ability to make natural clotting factors and delay your recovery.

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Habit Forming

No

Therapeutic Class

[HEMOSTATIC AGENTS]

FAQs

Botropase Injection 1 ml belongs to the group of haemostatic agents used to prevent bleeding in conditions such as oral bleeding, pulmonary bleeding, traumatic bleeding, postoperative bleeding, and other external and internal haemorrhages. It is a snake-venom based enzymatic mixture. Botropase Injection 1 ml contains ''Haemocoagulase (Bothrops atrox),'' which promotes the clotting process and arrests bleeding.
If given as an intravenous injection, Botropase Injection 1 ml takes 5 to 10minutes to start working and if given, intramuscularly or subcutaneously, it takes 20 to 30 minutes to work.
No, it is usually not considered safe to take Botropase Injection 1 ml with blood thinners. They work in opposite ways; Botropase Injection 1 ml helps blood clot, while blood thinners prevent clotting. Therefore, always check with your doctor before using them together.
The safety of this medicine during pregnancy has not been fully established. It should only be used if clearly needed and prescribed by your doctor. Talk to your doctor if you are pregnant or planning to become pregnant.
It is not known whether this medicine passes into breast milk. Tell your doctor if you are breastfeeding so they can weigh the benefits and potential risks before treatment.
Botropase Injection 1 ml is injected into a vein, a muscle, or under the skin. It is usually given by a doctor or nurse in a healthcare setting. Talk to your doctor if you have questions about how your injection is given.
It is highly recommended to avoid alcohol while using this medicine, as alcohol can interfere with blood clotting and your body's healing process. Talk to your doctor for personalised advice.
While Botropase Injection 1 ml is designed to help your blood clot at the site of a wound, there is a small risk of abnormal clots forming elsewhere in the body, especially in people with pre-existing risk factors. Talk to your doctor if you have concerns.
Mild pain or swelling is common and usually goes away on its own. However, if the pain gets worse or if you notice spreading redness, warmth, or pus, contact your doctor right away. Talk to your doctor if you are concerned.
Storage requirements depend on the specific manufacturer's instructions. Some formulations require refrigeration between 2°C and 8°C, while others can be kept at room temperature. Talk to your pharmacist to confirm how to store your specific product.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

47/1, 20th Km, Mysore Road Banglore - 560074.
Other Info - BOT0003
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