Haemocoagulase (bothrops Atrox)
About Haemocoagulase (bothrops Atrox)
Haemocoagulase (bothrops Atrox) is a prescription medicine given to help stop and prevent excessive bleeding. It is commonly used to manage severe blood loss during or after surgical procedures, dental operations, or physical injuries. By helping your blood clot more efficiently, it supports your body’s natural healing process.
Because this medicine is typically given in a clinical setting around the time of a medical procedure, your healthcare provider will decide how often you need it. Since it is given as an injection, you do not need to worry about taking it with food. To support your recovery, your doctor may suggest eating a balanced diet with nutrient-rich foods that naturally support healthy blood vessels and circulation.
While most people tolerate this medicine well, some may experience mild side effects, such as pain or swelling where the medicine was injected. If you experience any severe reactions, such as sudden chest pain or difficulty breathing, you must seek medical help immediately. Always discuss any unexpected symptoms with your doctor or pharmacist.
Do not use if you are allergic to snake venom-derived products, have active thrombosis (blood clots in the veins or arteries) or an ongoing thromboembolic disorder, or active disseminated intravascular coagulation (DIC), unless your doctor specifically advises its use.
If you are pregnant or breastfeeding, have children, are an older adult, or have kidney or liver disease, this medicine should be used only under medical supervision. Your doctor will determine the appropriate dose and monitor you as needed.
Uses of Haemocoagulase (bothrops Atrox)
Medicinal Benefits
When taken consistently as directed, this medicine may provide the following physiological benefits:
- Controls bleeding: It acts quickly at the source of the bleed to minimise blood loss during critical procedures.
- Supports tissue healing: Preventing blood from collecting under the skin (hematomas), it helps your tissues heal more cleanly and comfortably.
- Improves surgical outcomes: It gives your surgical team a clearer view during operations, reducing the risk of complications from excessive bleeding.
Directions for Use
- Follow your doctor's recommendations on the dosage and timing of this medication to achieve optimal results.
- Haemocoagulase (bothrops Atrox) will be administered by a healthcare professional.
- Do not self-administer.
Storage
Side Effects of Haemocoagulase (bothrops Atrox)
Common Side Effects (Usually mild)
- Pain, redness, or swelling at the injection site
- Mild headache
- Mild fever
- Nausea or slight stomach upset
Serious Side Effects (Consult your doctor right away)
- Swelling of your face, lips, tongue, or throat, severe skin rash, or difficulty breathing (signs of a severe allergic reaction)
- Sudden pain, warmth, or swelling in one leg, chest pain, or sudden shortness of breath (signs of abnormal blood clots)
Medicines Containing this Salt
View AllDrug Warnings
- Inspect before use: Do not use the medicine if the liquid is cloudy, discoloured, or contains floating particles.
- Use sterile equipment: Use a new sterile needle and syringe for each injection and dispose of them in a puncture-proof sharps container.
- Rotate injection sites: If self-injecting, use a different injection site each time to help prevent skin irritation.
- Inform your healthcare provider: Tell your dentist or surgeon that you have recently received medicine before any procedure.
- Monitor the injection site: Contact your doctor if you notice increasing redness, warmth, swelling, or fluid leaking from the injection site.
- Use in Children: They may be used in children when clinically necessary, but only under the supervision of a doctor. The dose is determined based on the child's age, weight, and medical condition.
- Monitoring during treatment: Your doctor may monitor your clinical response and, when appropriate, perform blood clotting tests to assess your condition and guide treatment, especially during or after surgery or if bleeding persists.
- Allergic to venom: Do not receive if you are allergic to snake venom-derived products or any ingredient in this medicine.
- When to Contact Your Doctor: If bleeding does not stop or worsens after treatment, seek medical attention immediately. Your doctor may need to identify the cause of the bleeding or recommend additional treatment.
Drug Interactions
- Blood thinners (anticoagulants): Medicines such as warfarin, heparin, or apixaban may reduce the effectiveness of Haemocoagulase (bothrops Atrox). They may also independently increase the risk of bleeding, so your doctor may recommend closer monitoring or adjust your treatment if both are used together.
- Fibrinolytic medicines (e.g., streptokinase, alteplase): These medicines dissolve blood clots and may reduce the effectiveness of Haemocoagulase (bothrops Atrox). Tell your doctor if you are receiving these treatments.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionIt is not known whether it is safe to consume alcohol with Haemocoagulase (bothrops Atrox). Please consult your doctor.
Pregnancy
cautionThere is limited information on the effects of Haemocoagulase (bothrops Atrox) on pregnancy. Please consult your doctor.
Breast Feeding
cautionThere is limited information on the effects of Haemocoagulase (bothrops Atrox) in nursing mothers. Please consult your doctor.
Driving
cautionThere is limited information on the effects of Haemocoagulase (bothrops Atrox) on driving abilities. Please consult your doctor.
Liver
cautionThere is limited information on the effects of Haemocoagulase (bothrops Atrox) on the liver. Please consult your doctor.
Kidney
cautionThere is limited information on the effects of Haemocoagulase (bothrops Atrox) on the kidney. Please consult your doctor.
Children
cautionHaemocoagulase (bothrops Atrox) should be used with caution in children. Please consult your doctor.
Habit Forming
Diet & Lifestyle Advise
- Avoid injuries: Stay away from activities with a high risk of falls, cuts, or physical injury while recovering.
- Prevent bleeding: Use a soft-bristled toothbrush and shave carefully to reduce the risk of bleeding from your gums or skin.
- Avoid certain painkillers: Do not take aspirin, ibuprofen, naproxen, or other anti-inflammatory pain relievers unless advised by your doctor, as they may increase the risk of bleeding.
- Attend follow-up visits: Keep all follow-up appointments so your healthcare team can monitor your healing and blood clotting.
Special Advise
In case of an anaphylactic reaction, report to the doctor immediately. Anaphylaxis is a reaction to the medicine, characterised by coughing, wheezing, nausea, vomiting, hives, rash, anxiety, confusion etc.
Patients Concern
Disease/Condition Glossary
Haemorrhage: Severe bleeding and a drastic loss of blood from damaged blood vessels, is called a haemorrhage. Bleeding could occur due to trauma injury, medical conditions or due to the use of certain drugs.
FAQs
Haemocoagulase (bothrops Atrox) belongs to the group of haemostatic agents used to prevent bleeding in conditions such as oral bleeding, pulmonary bleeding, traumatic bleeding, postoperative bleeding, and other external and internal haemorrhages. It is a snake-venom based enzymatic mixture. Haemocoagulase (bothrops Atrox) contains ''Haemocoagulase (Bothrops atrox),'' which promotes the clotting process and arrests bleeding.
If given as an intravenous injection, Haemocoagulase (bothrops Atrox) takes 5 to 10minutes to start working and if given, intramuscularly or subcutaneously, it takes 20 to 30 minutes to work.
No, it is usually not considered safe to take Haemocoagulase (bothrops Atrox) with blood thinners. They work in opposite ways; Haemocoagulase (bothrops Atrox) helps blood clot, while blood thinners prevent clotting. Therefore, always check with your doctor before using them together.
The safety of this medicine during pregnancy has not been fully established. It should only be used if clearly needed and prescribed by your doctor. Talk to your doctor if you are pregnant or planning to become pregnant.
It is not known whether this medicine passes into breast milk. Tell your doctor if you are breastfeeding so they can weigh the benefits and potential risks before treatment.
Haemocoagulase (bothrops Atrox) is injected into a vein, a muscle, or under the skin. It is usually given by a doctor or nurse in a healthcare setting. Talk to your doctor if you have questions about how your injection is given.
It is highly recommended to avoid alcohol while using this medicine, as alcohol can interfere with blood clotting and your body's healing process. Talk to your doctor for personalised advice.
While Haemocoagulase (bothrops Atrox) is designed to help your blood clot at the site of a wound, there is a small risk of abnormal clots forming elsewhere in the body, especially in people with pre-existing risk factors. Talk to your doctor if you have concerns.
Mild pain or swelling is common and usually goes away on its own. However, if the pain gets worse or if you notice spreading redness, warmth, or pus, contact your doctor right away. Talk to your doctor if you are concerned.
Storage requirements depend on the specific manufacturer's instructions. Some formulations require refrigeration between 2°C and 8°C, while others can be kept at room temperature. Talk to your pharmacist to confirm how to store your specific product.

