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Avil Injection 2 ml is an antiallergic medicine used in the treatment of allergic conditions caused due to pollen, dust mites, mould spores, food, pet dander, insect stings, and medicines/drugs. It contains pheniramine maleate which works by inhibiting the action of histamine (chemical messenger) responsible for allergy. Common side effects include injection site reactions, drowsiness, nausea, vomiting, stinging, etc.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Sanofi Consumer Healthcare

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Avil Injection 2 ml

Avil Injection 2 ml is an injectable medicine used to treat severe allergic reactions, skin allergies such as hives, and allergic reactions caused by medicines or insect bites. It belongs to a class of medicines called antihistamines and works quickly to relieve allergy symptoms. It is usually given under medical supervision when prompt treatment is needed.

Avil Injection 2 ml injection is usually used only for the short-term treatment of sudden or severe allergic reactions. Once your symptoms improve, your doctor will decide whether you need to switch to an oral antihistamine or receive any additional allergy treatment based on your condition.

Common side effects include drowsiness, dry mouth, and mild dizziness. Contact your doctor immediately if you experience severe sleepiness, rapid heartbeats, or difficulty passing urine.

Do not receive Avil Injection 2 ml if you are allergic to pheniramine or any of its ingredients, have severe central nervous system (CNS) depression, or if the patient is a premature baby or newborn infant unless your doctor decides it is absolutely necessary. Tell your doctor before treatment if you have glaucoma, an enlarged prostate, difficulty passing urine, asthma, emphysema, severe kidney or liver disease, or if you have taken MAO inhibitors within the past 14 days.

Avoid drinking alcohol or taking other sedatives with this medicine, as they can cause extreme sleepiness and slower breathing. If you are pregnant, breastfeeding, or an older adult, consult your doctor before receiving this medicine.

Avil Injection 2 ml can pass into breast milk and may cause excessive sleepiness or irritability in a breastfed baby. Your doctor will decide whether the benefits of treatment outweigh any possible risks and may recommend close monitoring or an alternative medicine if needed.

Uses of Avil Injection 2 ml

Your doctor may prescribe Avil Injection 2 ml to help manage the following conditions:

  • Severe allergic reactions: Avil Injection 2 ml helps reduce sudden swelling, hives, and breathing difficulties caused by severe allergic responses.
  • Supportive Treatment Only: For severe, life-threatening allergic reactions (anaphylaxis), Avil Injection 2 ml is used as supportive treatment and does not replace epinephrine (adrenaline), which is the first and most important emergency treatment. Seek immediate emergency medical care if symptoms such as severe difficulty breathing, swelling of the throat, or loss of consciousness occur.
  • Hives and skin allergies: It relieves intense skin itching, redness, and swelling.
  • Reactions to medicines or insect bites: It rapidly counteracts the body's allergic response to certain drugs or stings, bringing quick physical relief.

Key Benefits

When used as directed as part of your treatment plan, this medicine may provide the following benefits:

  • Fast Relief from Severe Allergic Reactions: Avil Injection 2 ml provides fast relief because it is injected directly into your body, allowing it to work more quickly than oral tablets. This makes it especially helpful during sudden or severe allergic reactions when prompt treatment is needed.
  • Relieves Allergic Skin Symptoms: By blocking the triggers of allergic symptoms, this medicine helps calm irritated skin, reduce swelling, and stop intense itching.
  • Promotes Faster Recovery: This helps you recover comfortably and quickly from distressing allergic episodes.
Side effects of Avil inj 2ml
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the steps to manage medication-triggered Nervousness:
  • Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
  • Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
  • Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
  • Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
  • You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Avil Injection 2 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Avil Injection 2 ml Works

When your body encounters an allergen, it releases a natural chemical called histamine. Histamine attaches to specific areas in your body, causing blood vessels to widen, skin to itch, and tissues to swell. Avil Injection 2 ml contains pheniramine maleate, which works by blocking these histamine docking sites. By stopping histamine from attaching, Avil Injection 2 ml quickly halts the chemical reaction that causes swelling, redness, and itching, bringing your body back to its normal state.
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Alcohol

Unsafe

Avoid consumption of alcohol while on treatment with Avil Injection 2 ml.

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Pregnancy

Unsafe

Avil Injection 2 ml is not recommended for use during pregnancy. Please consult your doctor if you have any concerns.

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Breast Feeding

Unsafe

Avil Injection 2 ml is not recommended for use during breastfeeding. Please consult your doctor if you have any concerns.

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Driving

Caution

Avil Injection 2 ml may cause drowsiness. Avoid driving or operating machinery.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have liver impairment/problems.

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Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Please consult your doctor if you have any concerns regarding the usage of Avil Injection 2 ml in children. Avil Injection 2 ml is not recommended for use in children below 1 year.

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Heart

Caution

Avil Injection 2 ml should be used with caution in patients with heart problems, as it may cause palpitations, blood pressure changes, or cardiovascular collapse in rare cases. Always consult your doctor before use to ensure it's safe for your condition.

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Geriatrics

Caution

Geriatric patients can receive Avil Injection 2 ml, but it may be more sensitive to side effects like drowsiness or dizziness. Doctors usually adjust the dose and monitor closely to ensure safe use.

What if I have taken an overdose of Avil Injection 2 ml

If you receive too much of this medicine, it can cause severe drowsiness, fever, dilated pupils, or confusion. In case of an accidental overdose or if you suspect someone has received too much, seek immediate medical attention.

Diet & Lifestyle Advise

  • Identify allergy triggers: Keep a record of your allergic episodes to pinpoint what causes them, such as specific foods, pollen, or insect bites, and try to avoid these triggers.
  • Stay hydrated: Drink plenty of water throughout the day to help manage dry mouth, which is a common side effect of this medicine.
  • Avoid alcohol and sedatives: Do not consume alcohol or sleeping aids while using Avil Injection 2 ml, as they can worsen drowsiness to dangerous levels.
  • Rest after your injection: Since this injection can make you very sleepy, plan to rest in a safe place immediately after receiving it. Do not drive or handle machinery.
  • Follow up with your doctor: If your allergy symptoms return after the injection wears off, contact your doctor. Depending on the cause and severity of your allergy, they may recommend oral antihistamines, additional treatment, or allergy testing. Seek immediate medical attention if severe symptoms, such as difficulty breathing or swelling of the face or throat, return.
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How Soon It Starts Working

The time required for Avil Injection 2 ml to start to work: The onset time of Avil Injection 2 ml has not been clinically established. The time for which the effects of Avil Injection 2 ml last: The duration of Avil Injection 2 ml’s effect is clinically not established.

What if you forget to take Avil Injection 2 ml

Since this medicine is usually given by a healthcare provider when needed for sudden allergy symptoms, missing a scheduled dose is unlikely. If you are on a specific treatment schedule and miss an injection, talk to your doctor or pharmacist immediately for guidance. Do not receive a double dose to make up for a missed one.

Storage

•Store Avil Injection 2 ml at room temperature, ideally between 15°C and 30°C (59°F to 86°F). •Keep the medication in its original packaging to protect it from direct light.

Drug Warnings

  • Inspect the liquid: Always check the injection solution before use. It should be completely clear and colourless; do not use it if you see particles, cloudiness, or discolouration.
  • Avoid driving: Do not drive, operate heavy machinery, or perform dangerous tasks for several hours after receiving Avil Injection 2 ml, as it causes significant drowsiness and slower reaction times.
  • Rotate injection sites: If you are receiving multiple injections into the muscle, ensure the injection site is rotated each time to prevent soreness and tissue damage.
  • Use sterile techniques: If administering at home under medical supervision, strictly follow sterile procedures, use a fresh needle for every dose, and dispose of used needles in an approved sharps container.
  • Watch for extreme sleepiness in the elderly: Older adults are more sensitive to the side effects of this medicine and may experience increased confusion or dizziness, which can raise the risk of falling.

Drug-Drug Interactions

verifiedApollotooltip
  • Avoid Combining with Drowsy Medicines: Using Avil Injection 2 ml with other medicines that cause drowsiness—such as sleeping pills, opioid pain relievers, muscle relaxants, or other antihistamines—can cause extreme sleepiness.
  • MAO Inhibitor Warning: Tell your doctor if you are taking MAO inhibitors (certain medicines used to treat depression or Parkinson's disease) or have taken them within the last 14 days. Combining these medicines with Avil Injection 2 ml can increase the risk of serious side effects and should be avoided unless advised by your doctor. 
PheniramineDihydroergotamine
Critical

Drug-Drug Interactions

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How does the drug interact with Avil inj 2ml:
Using Avil inj 2ml with selageline can cause severe high blood pressure

How to manage the interaction:
Taking Avil inj 2ml with Selegiline is not recommended, but it should be taken if prescribed by a doctor. However, if you experience headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
PheniramineDihydroergotamine
Critical
How does the drug interact with Avil inj 2ml:
Using dihydroergotamine together with phenylephrine may cause significant increases in blood pressure and the risk for complications may be increased.

How to manage the interaction:
Taking Avil inj 2ml with Dihydroergotamine is not recommended but can be taken if prescribed by a doctor. However, if you experience severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, pale or cold skin, chest pain or tightness, severe headache, irregular heartbeat, shortness of breath, blurred vision, confusion contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Avil inj 2ml:
Using phenylephrine together with linezolid can increase your blood pressure.

How to manage the interaction:
Taking Avil inj 2ml with Linezolid is not recommended but can be taken if prescribed by a doctor. However, if you experience severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Avil inj 2ml:
Using furazolidone together with phenylephrine can cause severe high blood pressure.

How to manage the interaction:
Taking Avil inj 2ml with Furazolidone is not recommended, but can be taken together if prescribed by a doctor. However, if you experience severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Avil inj 2ml:
Taking Avil inj 2ml with Topiramate can cause increased body temperature and decreased sweating.

How to manage the interaction:
Although there is a interaction between Avil inj 2ml and Topiramate, but it can be taken if prescribed by a doctor. However, if you experience drowsiness, dizziness, or lightheadedness contact your doctor immediately. Do not stop using any medications without talking to your doctor.
How does the drug interact with Avil inj 2ml:
Taking Avil inj 2ml with halothane can cause irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Avil inj 2ml and Halothane, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Avil inj 2ml:
Taking Avil inj 2ml with procarbazine can cause severe high blood pressure

How to manage the interaction:
Although taking Avil inj 2ml and Procarbazine together can evidently cause an interaction, but it can be taken if your doctor has suggested it. However, if you experience headache, blurred vision, confusion, seizures(fits), chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
PheniramineErgotamine
Severe
How does the drug interact with Avil inj 2ml:
Using ergotamine together with Avil inj 2ml can cause significant increase in blood pressure.

How to manage the interaction:
Although there is a interaction between Avil inj 2ml and Ergotamine, you can take these medicines together if prescribed by your doctor. However, if you experience severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
PheniramineDesipramine
Severe
How does the drug interact with Avil inj 2ml:
Taking desipramine with Avil inj 2ml can increase the risk of irregular heartbeats.

How to manage the interaction:
Co-administration of Avil inj 2ml with Desipramine can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
How does the drug interact with Avil inj 2ml:
Taking Avil inj 2ml and Potassium chloride together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Co-administration of Avil inj 2ml with Potassium chloride can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Avoid Alcohol: Do not consume alcohol while taking Avil Injection 2 ml. Alcohol greatly increases the sedative effects of this medication, which can lead to severe drowsiness, coordination issues, and breathing difficulties.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIHISTAMINE]

FAQs

Avil Injection 2 ml belongs to the class of medications called anti-histamines primarily used to treat allergic reactions. An allergy is a condition in which the immune system reacts abnormally to foreign substances such as pollen, dust mites, mold spores, food, pet dander, insect stings, and medicines/drugs.
Avil Injection 2 ml works by blocking the action of a chemical messenger called 'histamine' responsible for causing allergic reactions. Thereby Avil Injection 2 ml treats allergic conditions.
Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent drying of the mouth.
Avil Injection 2 ml may cause diarrhoea. Drink plenty of fluids and eat non-spicy food if you have diarrhoea. However, if the condition persists or worsens, consult a doctor.
MAO inhibitors may prolong and intensify the effect of Avil Injection 2 ml. Therefore, inform your doctor if you are taking MAO inhibitors (drugs used to treat depression) or if you have taken any anti-depressant medicine in the last 14 days.
Avil Injection 2 ml should be used with caution in patients above 60 years as it may cause dizziness, confusion, and hypotension (low blood pressure).
Limited information is available regarding the safety of Avil Injection 2 ml in pregnancy. Please consult the doctor if you are pregnant; the doctor will prescribe Avil Injection 2 ml only if the benefits outweigh the risks.
Avil Injection 2 ml may cause hypotension while administration; therefore the doctor will administer it slowly over a period of one minute to avoid a fall in blood pressure. It should be used with caution in patients above 60 years of age as it may cause low blood pressure and dizziness.
Avil Injection 2 ml does not have habit-forming tendencies as it is not addictive.
Taking Avil Injection 2 ml with cetirizine may increase the risk of side effects like dizziness and drowsiness. Therefore, consult the doctor before taking cetirizine with Avil Injection 2 ml to prevent any interactions.
Yes, Avil Injection 2 ml can be taken with paracetamol if advised by the doctor. They can be used together only when the patient has a fever along with allergic conditions like runny nose, common cold, hay fever and itchy skin.
Avil Injection 2 ml may cause sleepiness or drowsiness as a side effect. If you experience sleepiness or drowsiness, avoid driving or operating machinery.
No, Avil Injection 2 ml is not known to cause weight loss. Consult the doctor if you notice any changes in weight during treatment with Avil Injection 2 ml.
No, Avil Injection 2 ml and chlorpheniramine are not the same although they both belong to the class of medicines called antihistamines.
Yes, you can take vitamin C with Avil Injection 2 ml if advised by the doctor. Vitamin C is a supplement known to strengthen immunity, so taking them together can help to relieve common cold symptoms.
Avil Injection 2 ml may not increase blood pressure. However, consult the doctor if you have increased blood pressure while on treatment with Avil Injection 2 ml.
Avil Injection 2 ml is not a steroid. It belongs to the group of medications called anti-histamines used to treat allergic conditions.
Avil Injection 2 ml will be administered by the doctor or nurse. Do not self-administer.
Consult the doctor before taking Avil Injection 2 ml if you have severe liver disease. The doctor will adjust the dose based on your medical condition.
The side effects of Avil Injection 2 ml include dizziness, nausea, vomiting, dry mouth, tingling or burning sensation at the injection site, rapid or irregular heartbeat, drowsiness, restlessness, weakness or headache. Consult the doctor if any of these side effects persist or worsen.
Avil Injection 2 ml is not recommended for use in children below 1 year. Please consult your doctor if you have any concerns regarding the usage of Avil Injection 2 ml in children.
No, you should not drive or operate machinery after receiving Avil Injection 2 ml. This medicine causes significant drowsiness and can slow your reaction times. Talk to your doctor to understand when it is safe to drive again.
Mild soreness at the injection site is common. However, if you notice persistent pain, redness, swelling, or warmth, contact your healthcare provider right away. Talk to your doctor for further advice.
You should exercise extreme caution if you have glaucoma, as Avil Injection 2 ml can increase pressure inside the eye and worsen your condition. Talk to your doctor before receiving this medicine.
No, you must avoid alcohol while using Avil Injection 2 ml. Alcohol increases the sedative effects of this medicine, which can lead to extreme drowsiness and dangerous breathing problems. Talk to your doctor if you have questions.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

3rd floor, Sanofi house, CTS NO 117-B, L&T Business Park, Saki Vihar road, Powai, Mumbai-400072
Other Info - AVI0001
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