I have been taking Bupron and Lithocent CR for 2 to 3 years. Recently, my doctor reduced my Depran dosage and started me on Petril Beta 20. Since making this switch, I am experiencing depression, sleeplessness, lightheadedness, and a lack of mental clarity. Could these symptoms be side effects of this medication change, and what should I do?

Yes, your symptoms can definitely be related to these medication changes. Reducing your previous antidepressant (escitalopram) can cause a temporary return of depression and sleep issues. Meanwhile, starting a new combination of a beta-blocker (propranolol) and a sedative (clonazepam) commonly causes lightheadedness due to lowered blood pressure, along with temporary mental cloudiness. These are known and manageable reactions as your body adjusts. Please consult your prescribing doctor promptly to share these symptoms. They can safely fine-tune your dosages or modify your plan. Avoid stopping or changing your medications on your own, as sudden changes can make you feel worse.