Yes, your symptoms can definitely be related to these medication changes. Reducing your previous antidepressant (escitalopram) can cause a temporary return of depression and sleep issues. Meanwhile, starting a new combination of a beta-blocker (propranolol) and a sedative (clonazepam) commonly causes lightheadedness due to lowered blood pressure, along with temporary mental cloudiness. These are known and manageable reactions as your body adjusts. Please consult your prescribing doctor promptly to share these symptoms. They can safely fine-tune your dosages or modify your plan. Avoid stopping or changing your medications on your own, as sudden changes can make you feel worse.