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Buclizine

About Buclizine

Buclizine is an antihistamine medicine used to help relieve motion sickness, nausea, dizziness, and certain allergy symptoms. Buclizine has also been used as an appetite stimulant in some countries and products. Its approved uses can vary, so take it only for the condition for which your doctor has recommended it.

This medicine blocks the effects of histamine, a chemical your body releases during an allergic reaction. It also affects signals involved in balance and nausea, which can help prevent motion sickness. Its appetite-stimulating effect is believed to involve its antihistamine and antiserotonin effects on parts of the brain involved in appetite control.

Take this medicine exactly as prescribed. Measure the syrup using the measuring device supplied with the product rather than a household spoon. It can generally be taken with or without food.

Common side effects include drowsiness, dry mouth, dizziness, and tiredness. Avoid driving or doing activities that require full alertness until you know how this medicine affects you. Consult your doctor right away if you develop severe confusion, difficulty passing urine, a fast or irregular heartbeat, or signs of a serious allergic reaction.

Tell your doctor before taking this medicine if you have narrow-angle glaucoma, difficulty passing urine, prostate problems, asthma or another breathing condition. Also tell your doctor about all medicines you take because alcohol and medicines that cause drowsiness can increase its sedating effects.

Buclizine should be given to children only when specifically prescribed by a paediatrician or other qualified healthcare professional. The appropriate age, dose, and duration depend on the child's age, weight, condition, and the particular product. Do not use an adult dose or assume that one buclizine syrup has the same paediatric instructions as another.

Tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding before taking this medicine. Available pregnancy safety classifications and recommendations may differ between products and countries, so your doctor should assess whether treatment is appropriate.

Uses of Buclizine

Buclizine is used to treat allergic conditions, nausea and vomiting, motion sickness. The detailed uses of Buclizine are as follows: • Motion sickness: Buclizine is commonly used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness. It acts on the vomiting center in the brain to reduce symptoms. • Vertigo and vestibular disorders: Buclizine helps manage vertigo by calming the inner ear and balance centers, making it useful in conditions like Meniere’s disease. • Allergic conditions: As an antihistamine, Buclizine is effective in treating allergic symptoms such as sneezing, runny nose, watery eyes, and skin rashes. It works by blocking histamine receptors. • Appetite stimulant: Buclizine is sometimes used to stimulate appetite, especially in children with poor eating habits. Though this use is off-label in some regions, it has been practiced clinically.

Medicinal Benefits

Buclizine may provide several benefits depending on why it has been prescribed:

  • Helps improve appetite: It may increase the desire to eat in people with reduced appetite, supporting adequate food intake when used alongside appropriate nutritional care.
  • Helps prevent motion sickness: It can reduce nausea, vomiting, and dizziness caused by movement during travel.
  • Relieves allergy symptoms: Its antihistamine action may reduce sneezing, a runny nose, watery eyes, and itching.

Directions for Use

  • Buclizine should be taken with meals to prevent stomach upset.
  • It is usually recommended 3-4 times daily; however, follow your doctor’s advice regarding the dosage and duration.
  • Measure the prescribed dose using a measuring cup and administer it orally.
  • Avoid using regular household spoons, as they may not measure the dose correctly. Shake well before use.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Buclizine

Common Side Effects (Usually Mild):

  • Drowsiness or sleepiness
  • Dry mouth, nose, or throat
  • Dizziness
  • Headache
  • Mild stomach discomfort or nausea


Serious Side Effects (Consult your doctor right away):

  • Swelling of the face, lips, tongue, or throat, hives, or difficulty breathing
  • Severe dizziness, confusion, or unusual changes in alertness
  • Difficulty passing urine
  • Severe blurred vision or eye pain
  • Fast, pounding, or irregular heartbeat

Drug Warnings

  • Measure each dose carefully: Use the measuring device supplied with the medicine rather than a household spoon.
  • Avoid driving if you feel drowsy: This medicine may cause sleepiness, dizziness, or reduced alertness. Do not drive, cycle, or operate machinery if affected.
  • Avoid alcohol: Alcohol can increase drowsiness, dizziness, and reduced alertness caused by this medicine.
  • Check other medicines: Cold, cough, allergy, sleeping, or nausea medicines may contain ingredients that cause similar side effects. Check with your doctor or pharmacist before combining them.
  • Use in children only with medical guidance: Do not give buclizine syrup to a child unless a paediatrician or other qualified healthcare professional has confirmed that the specific product is suitable and advised the correct dose.
  • Review persistent appetite loss: If your appetite remains poor despite treatment, or you continue to lose weight, consult your doctor. Loss of appetite can sometimes be caused by an underlying medical condition that needs treatment.
  • Tell your doctor before allergy testing: Antihistamines can affect allergy skin-test results. Ask your doctor whether the medicine needs to be stopped before testing.
  • Check your specific product: Buclizine may be available in different formulations and combination products in India. Check the active ingredients and strength on the label rather than relying on a brand name alone.

Drug Interactions

  • Sedatives and sleeping medicines (e.g. diazepam, clonazepam, zolpidem): Taking these medicines with buclizine may increase drowsiness, dizziness, and reduced alertness.
  • Opioid pain medicines (e.g. morphine, codeine, tramadol): Combining these medicines may increase sedation and, with some opioids, the risk of breathing problems.
  • Other sedating antihistamines (e.g. diphenhydramine, chlorpheniramine, promethazine): Taking them together may increase drowsiness, dry mouth, blurred vision, constipation, and difficulty passing urine.
  • MAO inhibitor antidepressants (e.g. phenelzine, tranylcypromine): These medicines may increase or prolong some effects of antihistamines. Tell your doctor if you take or have recently taken an MAO inhibitor.
  • Medicines with anticholinergic effects (e.g. oxybutynin, atropine): Taking these medicines together may increase dry mouth, blurred vision, constipation, and difficulty passing urine.

Drug-Drug Interactions Checker List:

Safety Advice

  • Safety Warning

    Alcohol

    caution

    Buclizine may enhance the CNS depressant effect of alcohol. Therefore, avoid the consumption of alcohol.

  • Safety Warning

    Pregnancy

    caution

    Buclizine belongs to pregnancy category C. Buclizine may not be recommended during pregnancy. However, please consult the doctor if you are pregnant or planning pregnancy.

  • Safety Warning

    Breast Feeding

    caution

    Buclizine may not be recommended during breastfeeding. However, please consult the doctor if you are breastfeeding.

  • Safety Warning

    Driving

    caution

    Buclizine may impair your ability to drive or operate machinery. So, drive or operate machinery only if you are alert.

  • Safety Warning

    Liver

    consult your doctor

    Limited information is available. If you have a history of liver disease, inform the doctor before taking Buclizine.

  • Safety Warning

    Kidney

    consult your doctor

    Limited information is available. If you have a history of kidney disease, inform the doctor before taking Buclizine.

  • Safety Warning

    Children

    consult your doctor

    Please consult the doctor if you have any concerns regarding the usage of Buclizine in children.

Habit Forming

No

Diet & Lifestyle Advise

  • Eat small, frequent meals: If you have poor appetite, smaller meals may be easier to manage than large meals.
  • Choose nutrient-rich foods: Include appropriate sources of protein, whole grains, fruits, vegetables, and healthy fats to support your nutritional needs.
  • Stay hydrated: Drinking enough fluids may also help relieve dry mouth caused by this medicine.
  • Reduce motion sickness triggers: During travel, look towards the horizon and avoid reading or prolonged screen use if these activities worsen your symptoms.
  • Choose lighter meals before travel: Heavy or greasy meals may worsen nausea in some people.

Patients Concern

Disease/Condition Glossary

Allergy: It occurs when the immune system responds to foreign elements known as allergens, such as pollen, dust mites, pet dander, mould spores, medicines, food or insect bites. Symptoms include itching, watery eyes, swelling, runny nose, itchy skin, and sneezing.

Nausea & Vomiting: Nausea is an uneasy feeling in which the person feels an urge to vomit, whereas vomiting is an uncontrollable reflex that expels the contents of the stomach through the mouth. Nausea and vomiting may occur separately or together. The common causes include motion sickness, emotional stress, indigestion, food poisoning, high fever or overeating.

Motion sickness: It is an illness caused due to motion during travelling by car, plane, boat, or train. The body’s sensory organs send mixed signals to the brain, causing dizziness, light-headedness, nausea or vomiting. Symptoms include nausea, vomiting, fatigue, uneasiness, dizziness, trouble maintaining balance or loss of balance.

FAQs

This medicine may cause drowsiness, dizziness, or slower reactions. Do not drive or operate machinery until you know how it affects you.

Give this medicine to a child only if a paediatrician or other qualified healthcare professional has specifically recommended it. The appropriate dose depends on the child's age, weight, condition, and the specific syrup formulation.

Use it only for the duration recommended by your doctor. If your appetite does not improve within the expected treatment period, or you continue losing weight, consult your doctor rather than continuing the medicine on your own.

It blocks histamine signals in pathways involved in balance and movement. This reduces signals reaching the part of the brain that triggers nausea and vomiting during travel.

Yes. Drowsiness can occur with buclizine. Avoid driving or other activities requiring full alertness if you feel sleepy.

Avoid alcohol while taking this medicine because it can increase drowsiness, dizziness, and reduced alertness.

It can generally be taken with or without food. Follow the instructions provided with your specific product and any advice from your doctor.

Take the missed dose when you remember unless it is nearly time for your next dose. If the next dose is due soon, skip the missed dose. Do not take two doses together.

Tell your doctor if you are pregnant or planning a pregnancy before using this medicine. Pregnancy recommendations for buclizine can vary between products and authorities, so your doctor will decide whether treatment is appropriate based on your individual situation.

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