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compositionComposition:BUCLIZINE-6MG
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Longifene Syrup is used to treat allergic conditions, nausea and vomiting, and motion sickness. It contains Buclizine, which works by blocking the action of chemical messengers that cause allergic symptoms. Thus, it helps treat allergic conditions. It prevents nausea and vomiting by inhibiting the vomiting centre in the brain from receiving the nerve messengers that cause motion sickness.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

BUCLIZINE-6MG

Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Longifene Syrup

Longifene Syrup is an antihistamine medicine used to help relieve motion sickness, nausea, dizziness, and certain allergy symptoms. Buclizine has also been used as an appetite stimulant in some countries and products. Its approved uses can vary, so take it only for the condition for which your doctor has recommended it.

This medicine blocks the effects of histamine, a chemical your body releases during an allergic reaction. It also affects signals involved in balance and nausea, which can help prevent motion sickness. Its appetite-stimulating effect is believed to involve its antihistamine and antiserotonin effects on parts of the brain involved in appetite control.

Take this medicine exactly as prescribed. Measure the syrup using the measuring device supplied with the product rather than a household spoon. It can generally be taken with or without food.

Common side effects include drowsiness, dry mouth, dizziness, and tiredness. Avoid driving or doing activities that require full alertness until you know how this medicine affects you. Consult your doctor right away if you develop severe confusion, difficulty passing urine, a fast or irregular heartbeat, or signs of a serious allergic reaction.

Tell your doctor before taking this medicine if you have narrow-angle glaucoma, difficulty passing urine, prostate problems, asthma or another breathing condition. Also tell your doctor about all medicines you take because alcohol and medicines that cause drowsiness can increase its sedating effects.

Buclizine should be given to children only when specifically prescribed by a paediatrician or other qualified healthcare professional. The appropriate age, dose, and duration depend on the child's age, weight, condition, and the particular product. Do not use an adult dose or assume that one buclizine syrup has the same paediatric instructions as another.

Tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding before taking this medicine. Available pregnancy safety classifications and recommendations may differ between products and countries, so your doctor should assess whether treatment is appropriate.

Uses of Longifene Syrup

Your doctor may prescribe Longifene Syrup to help manage the following conditions:

  • Loss of appetite: It may help increase appetite when a doctor has determined that treatment with an appetite stimulant is appropriate.
  • Motion sickness: It helps prevent or relieve nausea, vomiting, and dizziness caused by movement during travel.
  • Allergy symptoms: It may help relieve symptoms such as sneezing, a runny nose, watery eyes, and itching by reducing the effects of histamine.

Key Benefits

Longifene Syrup may provide several benefits depending on why it has been prescribed:

  • Helps improve appetite: It may increase the desire to eat in people with reduced appetite, supporting adequate food intake when used alongside appropriate nutritional care.
  • Helps prevent motion sickness: It can reduce nausea, vomiting, and dizziness caused by movement during travel.
  • Relieves allergy symptoms: Its antihistamine action may reduce sneezing, a runny nose, watery eyes, and itching.

Directions for Use

  • Longifene Syrup should be taken with meals to prevent stomach upset.
  • It is usually recommended 3-4 times daily; however, follow your doctor’s advice regarding the dosage and duration.
  • Measure the prescribed dose using a measuring cup and administer it orally.
  • Avoid using regular household spoons, as they may not measure the dose correctly. Shake well before use.

How Longifene Syrup Works

Longifene Syrup contains buclizine, an antihistamine medicine. It blocks H1 histamine receptors, which are sites where histamine attaches to produce allergy symptoms. Histamine is a natural chemical released by the body during an allergic reaction. Blocking its effects helps reduce symptoms such as sneezing, itching, a runny nose, and watery eyes. For motion sickness and nausea, buclizine mainly blocks H1 receptors in the vestibular system, the part of the inner ear and brain involved in balance and sensing movement. This reduces signals travelling to the part of the brain that triggers nausea and vomiting. Buclizine's appetite-stimulating effect is believed to involve both antihistamine and antiserotonin activity in the hypothalamus, a part of the brain involved in regulating hunger and appetite. This may increase the desire to eat, although the exact way buclizine increases appetite is not fully established.
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Alcohol

Caution

Longifene Syrup may enhance the CNS depressant effect of alcohol. Therefore, avoid the consumption of alcohol.

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Pregnancy

Caution

Buclizine belongs to pregnancy category C. Longifene Syrup may not be recommended during pregnancy. However, please consult the doctor if you are pregnant or planning pregnancy.

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Breast Feeding

Caution

Longifene Syrup may not be recommended during breastfeeding. However, please consult the doctor if you are breastfeeding.

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Driving

Caution

Longifene Syrup may impair your ability to drive or operate machinery. So, drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Limited information is available. If you have a history of liver disease, inform the doctor before taking Longifene Syrup .

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Kidney

Consult your doctor

Limited information is available. If you have a history of kidney disease, inform the doctor before taking Longifene Syrup .

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Children

Consult your doctor

Please consult the doctor if you have any concerns regarding the usage of Longifene Syrup in children.

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Heart

Caution

Take Longifene Syrup with caution, especially if you have a history of heart diseases/conditions. The dose may be adjusted by your doctor as required.

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Geriatrics

Caution

Longifene Syrup should be used with caution in elderly patients. Please consult your doctor before use.

What if I have taken an overdose of Longifene Syrup

Taking too much buclizine may cause severe drowsiness, dizziness, confusion, unusual excitement, a fast heartbeat, or other serious symptoms. Seek urgent medical attention if an overdose is suspected.

Diet & Lifestyle Advise

  • Eat small, frequent meals: If you have poor appetite, smaller meals may be easier to manage than large meals.
  • Choose nutrient-rich foods: Include appropriate sources of protein, whole grains, fruits, vegetables, and healthy fats to support your nutritional needs.
  • Stay hydrated: Drinking enough fluids may also help relieve dry mouth caused by this medicine.
  • Reduce motion sickness triggers: During travel, look towards the horizon and avoid reading or prolonged screen use if these activities worsen your symptoms.
  • Choose lighter meals before travel: Heavy or greasy meals may worsen nausea in some people.
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How Soon It Starts Working

The time required for Longifene Syrup to start to work: Longifene Syrup ideally shows its action within 30 minutes to 1 hour after administration. The time for which the effects of Longifene Syrup last: The duration of action for Longifene Syrup is unknown.

What if you forget to take Longifene Syrup

If you miss a regularly scheduled dose, take it when you remember unless it is nearly time for your next dose. If the next dose is due soon, skip the missed dose and continue with your usual schedule. Do not take two doses together to make up for a missed dose.

Storage

• Store Longifene Syrup at room temperature, preferably between 20°C and 25°C, or according to the storage instructions on the product label.

Drug Warnings

  • Measure each dose carefully: Use the measuring device supplied with the medicine rather than a household spoon.
  • Avoid driving if you feel drowsy: This medicine may cause sleepiness, dizziness, or reduced alertness. Do not drive, cycle, or operate machinery if affected.
  • Avoid alcohol: Alcohol can increase drowsiness, dizziness, and reduced alertness caused by this medicine.
  • Check other medicines: Cold, cough, allergy, sleeping, or nausea medicines may contain ingredients that cause similar side effects. Check with your doctor or pharmacist before combining them.
  • Use in children only with medical guidance: Do not give buclizine syrup to a child unless a paediatrician or other qualified healthcare professional has confirmed that the specific product is suitable and advised the correct dose.
  • Review persistent appetite loss: If your appetite remains poor despite treatment, or you continue to lose weight, consult your doctor. Loss of appetite can sometimes be caused by an underlying medical condition that needs treatment.
  • Tell your doctor before allergy testing: Antihistamines can affect allergy skin-test results. Ask your doctor whether the medicine needs to be stopped before testing.
  • Check your specific product: Buclizine may be available in different formulations and combination products in India. Check the active ingredients and strength on the label rather than relying on a brand name alone.

Drug-Drug Interactions

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  • Sedatives and sleeping medicines (e.g. diazepam, clonazepam, zolpidem): Taking these medicines with buclizine may increase drowsiness, dizziness, and reduced alertness.
  • Opioid pain medicines (e.g. morphine, codeine, tramadol): Combining these medicines may increase sedation and, with some opioids, the risk of breathing problems.
  • Other sedating antihistamines (e.g. diphenhydramine, chlorpheniramine, promethazine): Taking them together may increase drowsiness, dry mouth, blurred vision, constipation, and difficulty passing urine.
  • MAO inhibitor antidepressants (e.g. phenelzine, tranylcypromine): These medicines may increase or prolong some effects of antihistamines. Tell your doctor if you take or have recently taken an MAO inhibitor.
  • Medicines with anticholinergic effects (e.g. oxybutynin, atropine): Taking these medicines together may increase dry mouth, blurred vision, constipation, and difficulty passing urine.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • Alcohol: Avoid alcohol because it can increase drowsiness, dizziness, poor coordination, and reduced alertness. 
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIHISTAMINE, ANTIALLERGIC]

FAQs

This medicine may cause drowsiness, dizziness, or slower reactions. Do not drive or operate machinery until you know how it affects you.
Give this medicine to a child only if a paediatrician or other qualified healthcare professional has specifically recommended it. The appropriate dose depends on the child's age, weight, condition, and the specific syrup formulation.
Use it only for the duration recommended by your doctor. If your appetite does not improve within the expected treatment period, or you continue losing weight, consult your doctor rather than continuing the medicine on your own.
It blocks histamine signals in pathways involved in balance and movement. This reduces signals reaching the part of the brain that triggers nausea and vomiting during travel.
Yes. Drowsiness can occur with buclizine. Avoid driving or other activities requiring full alertness if you feel sleepy.
Avoid alcohol while taking this medicine because it can increase drowsiness, dizziness, and reduced alertness.
It can generally be taken with or without food. Follow the instructions provided with your specific product and any advice from your doctor.
Take the missed dose when you remember unless it is nearly time for your next dose. If the next dose is due soon, skip the missed dose. Do not take two doses together.
Tell your doctor if you are pregnant or planning a pregnancy before using this medicine. Pregnancy recommendations for buclizine can vary between products and authorities, so your doctor will decide whether treatment is appropriate based on your individual situation.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase III, New Delhi - 110020
Other Info - LON0020
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