Nor Ursodeoxycholic Acid
About Nor Ursodeoxycholic Acid
Nor Ursodeoxycholic Acid is used to treat primary biliary cholangitis (a liver autoimmune disease), cholestatic liver problems, fatty liver disease, liver inflammation in cystic fibrosis sufferers, and gallstones. It improves bile flow, decreases liver inflammation, and lowers the risk of liver damage.
Nor Ursodeoxycholic Acid contains Nor-Ursodeoxycholic Acid, which works by improving bile flow through the liver and bile ducts. It produces a special “bicarbonate-rich” bile that protects the ducts from irritation, reduces inflammation, and helps prevent further damage. Nor-UDCA also reduces harmful bile acids, supports liver cell recovery, and may slow the progression of liver scarring (fibrosis). Together, these actions help relieve cholestasis and protect the liver over time.
Nor Ursodeoxycholic Acid may cause common side effects such as abdominal pain, diarrhoea, nausea, and dizziness. Most of these side effects do not require medical attention and will resolve gradually over time. However, consult your doctor if any of these side effects persist.
Do not take Nor Ursodeoxycholic Acid if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and any medications you are taking to rule out any potential interactions.
Medicinal Benefits
- Nor Ursodeoxycholic Acid protects liver cells from injury caused by toxic bile acids and improves liver function.
- It is an effective therapy for primary biliary cirrhosis (a chronic autoimmune liver disease), by slowing its progression and improving overall liver function.
- Nor Ursodeoxycholic Acid helps manage associated liver disease. It improves liver function and helps clear obstructions in the bile ducts.
- This medicine can relieve symptoms of bile reflux gastritis, a condition in which bile flows backwards into the stomach and oesophagus, causing irritation.
Directions for Use
- Nor Ursodeoxycholic Acid can be taken with food to prevent stomach upset or as advised by the doctor.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
- Swallow Nor Ursodeoxycholic Acid as a whole with a glass of water.
- Do not chew, crush, or break it.
Storage
Side Effects of Nor Ursodeoxycholic Acid
- Abdominal pain
- Diarrhoea
- Nausea
- Dizziness
- Indigestion
Drug Warnings
- Do not take Nor Ursodeoxycholic Acid if you are allergic to any of its contents.
- Also, avoid taking Nor Ursodeoxycholic Acid if you have inflammation of the gallbladder and bile ducts, narrowing or blockage of bile ducts, biliary colic, calcified gallstones, improper constriction of the gallbladder, gastric or duodenal ulcer.
- Inform your doctor before taking Nor Ursodeoxycholic Acid if you have variceal bleeding (high blood pressure in portal veins), ascites (excess abdominal fluid), liver encephalopathy or liver disease.
- Consult your doctor if you are pregnant or breastfeeding.
- Tell your doctor if you are taking, have recently taken or might take any other medicines to prevent any potential interactions.
Drug Interactions
Drug-Drug Interactions: Nor Ursodeoxycholic Acid may interact with antibiotics (ciprofloxacin, dapsone), hormones (oestrogen), and antacids (aluminium hydroxide, aluminium carbonate, magaldrate).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform your doctor if you have biliary obstruction, liver impairment, ascites (excess abdominal fluid), or liver encephalopathy.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol while taking Nor Ursodeoxycholic Acid as it may cause increased dizziness and liver damage.
Pregnancy
consult your doctorPlease consult your doctor if you have any concerns regarding this. Nor Ursodeoxycholic Acid should be used during pregnancy only if absolutely necessary.
Breast Feeding
consult your doctorConsult your doctor before taking Nor Ursodeoxycholic Acid; your doctor will decide whether breastfeeding mothers can take Nor Ursodeoxycholic Acid or not.
Driving
consult your doctorIt is unknown whether Nor Ursodeoxycholic Acid affects your ability to drive or operate. Please consult your physician.
Liver
consult your doctorPlease consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
consult your doctorPlease consult your doctor if you have a liver impairment or any concerns regarding this.
Children
consult your doctorNor Ursodeoxycholic Acid should be given to children only if prescribed by the doctor/paediatrician.
Habit Forming
Diet & Lifestyle Advise
- Include foods such as bell peppers, citrus fruits, leafy vegetables, tomatoes, milk, fish, low-fat dairy, beans, nuts, lentils, tofu and tempeh in your diet.
- Eat a healthy, well-balanced diet, which includes fruits and vegetables.
- Foods rich in vitamins B and C and calcium are good for the gallbladder.
- Plant-based protein foods such as beans, nuts, lentils, tofu and tempeh help prevent gallbladder disease.
- Avoid high-fat, trans-fat and processed foods.
- White bread, white pasta and sugars should be avoided.
- Avoid smoking and alcohol consumption.
Patients Concern
Disease/Condition Glossary
Cholestatic Liver Disorders: Cholestatic liver disorders are conditions in which bile flow from the liver slows or becomes blocked, leading to a buildup of bile within the liver. This can cause irritation, inflammation, and damage. Common causes include bile duct swelling, gallstones, autoimmune diseases like PSC or PBC, certain medications, or genetic problems. People may experience itching, tiredness, jaundice (yellowing of eyes/skin), dark urine, pale stools, or stomach discomfort.
Primary Sclerosing Cholangitis (PSC): is a long-term disease in which the bile ducts inside and outside the liver become inflamed and gradually scarred, causing the ducts to narrow and blocking the flow of bile. Over time, this buildup of bile can damage the liver. People with PSC may experience fatigue, itching, abdominal discomfort, or jaundice, though some have no symptoms in the early stages. The exact cause is unknown, but it is often associated with immune-related conditions like ulcerative colitis.
Primary biliary cholangitis: Primary biliary cholangitis, formerly known as primary biliary cirrhosis, is an autoimmune disease caused by bile duct damage in the liver. Bile ducts are small channels that carry bile (digestive fluid) from the liver to the small intestine, where it breaks down fats and aids in their absorption. Biliary cirrhosis causes a build-up of bile in the liver, which leads to liver damage.
Gallbladder stones: The Gallbladder is a small organ located below the liver that stores bile and helps with digestion. Excess cholesterol in bile can lead to gallstone formation. Gallstones can cause abdominal pain, dark urine and stools, indigestion, diarrhoea, nausea and vomiting.
Cystic fibrosis: It is a hereditary disease that affects the digestive system and lungs. In this condition, the body produces a thick and sticky fluid that obstructs the pancreas and clogs the lungs.
FAQs
Nor Ursodeoxycholic Acid is used to treat primary biliary cholangitis (a liver autoimmune disease), cholestatic liver problems, fatty liver disease, liver inflammation in cystic fibrosis sufferers, and gallstones.
Do not discontinue Nor Ursodeoxycholic Acid without consulting your doctor. To treat your condition effectually, continue taking Nor Ursodeoxycholic Acid for as long as prescribed. Do not hesitate to speak with your doctor if you experience any difficulty taking Nor Ursodeoxycholic Acid.
It is unknown whether Nor Ursodeoxycholic Acid is safe for use in children. Hence, please consult your paediatrician.
Nor Ursodeoxycholic Acid contains Nor-Ursodeoxycholic Acid, which works by improving bile flow through the liver and bile ducts. It produces a special “bicarbonate-rich” bile that protects the ducts from irritation, reduces inflammation, and helps prevent further damage. Nor-UDCA also reduces harmful bile acids, supports liver cell recovery, and may slow the progression of liver scarring (fibrosis). Together, these actions help relieve cholestasis and protect the liver over time.
Avoid taking aluminium-containing antacids along with Nor Ursodeoxycholic Acid, as they might interfere with its absorption. Maintain a 2-hour gap between the two.
Yes, Nor Ursodeoxycholic Acid is safe to use if prescribed by the doctor. Like all medicines, Nor Ursodeoxycholic Acid may also cause side effects in some people. However, if any of the side effects are bothersome, please consult the doctor.
