Benidipine+nebivolol
About Benidipine+nebivolol
Benidipine+nebivolol belongs to a class of medications called 'anti-hypertensives,' primarily used to treat hypertension (high blood pressure). Hypertension is a lifelong (chronic) condition in which the blood pressure against the artery walls becomes very high. It can lead to complications such as heart attack, stroke, and long-term kidney disease.
Benidipine+nebivolol contains two medications: Benidipine (a calcium channel blocker) and Nebivolol (a beta-blocker). Benidipine works by blocking calcium from entering the smooth muscle cells of blood vessels, which helps widen the blood vessels and reduce pressure on them, making it easier for the heart to pump blood throughout the body. Nebivolol works by blocking beta-1 receptors in the heart, which slows the heart rate and relaxes blood vessels, thereby improving blood flow and lowering blood pressure. Together, Benidipine+nebivolol effectively treats high blood pressure.
You are advised to take Benidipine+nebivolol for as long as your doctor has prescribed it, depending on your medical condition. In some cases, Benidipine+nebivolol may cause common side effects, such as headache, nausea, dizziness, fatigue (tiredness), hypotension (low blood pressure), bradycardia (slow heartbeat), palpitation (irregular heartbeats), oedema (swelling), and stomach pain. Most of these side effects will resolve gradually over time without requiring medical attention. However, if you experience any of these side effects persistently, please consult your doctor.
Before taking Benidipine+nebivolol, inform your doctor if you are allergic to any of its ingredients. Also, let your doctor know if you have any medical conditions, such as diabetes (high blood sugar), respiratory problems (asthma, emphysema, bronchitis), circulation problems, pheochromocytoma (a tumour of the adrenal gland), or thyroid, liver, kidney, or heart problems. Please consult your doctor before taking Benidipine+nebivolol if you are pregnant or planning to become pregnant. Avoid breastfeeding while using Benidipine+nebivolol, as it contains Nebivolol, which may pass into breast milk and harm the baby. Benidipine+nebivolol may cause dizziness and sleepiness, so avoid driving or operating machines until you are mentally alert.
Uses of Benidipine+nebivolol
Medicinal Benefits
Benidipine+nebivolol is an antihypertensive medication primarily used to treat hypertension (high blood pressure). It contains Benidipine and Nebivolol. Benidipine is a calcium channel blocker that blocks calcium from entering the smooth muscle cells of blood vessels, helping to widen the blood vessels and reduce pressure on them. Nebivolol is a beta-blocker that slows the heart rate and relaxes blood vessels, which helps improve blood flow and lowers blood pressure. Together, Benidipine+nebivolol effectively treats high blood pressure and helps reduce the risk of stroke, heart attack, kidney problems, or other complications in the future.
Directions for Use
- Benidipine+nebivolol can be taken with or without food or as advised by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
- Swallow Benidipine+nebivolol as a whole with a glass of water.
- Do not break, crush, or chew it.
Storage
Side Effects of Benidipine+nebivolol
- Headache
- Nausea
- Dizziness
- Stomach pain
- Oedema (swelling)
- Fatigue (tiredness)
- Hypotension (low blood pressure)
- Bradycardia (slow heartbeat)
- Palpitation (irregular heartbeats)
Drug Warnings
Do not take Benidipine+nebivolol if you are allergic to any of its ingredients. Avoid taking Benidipine+nebivolol if you have any severe liver disease or heart problems, such as heart failure, sick sinus syndrome (a heart rhythm disorder), second- or third-degree heart block, severe bradycardia (very slow heartbeats), and cardiogenic shock (a medical emergency where the heart suddenly fails to pump enough blood to vital organs). Do not stop taking Benidipine+nebivolol abruptly without consulting your doctor, as it may worsen your condition or cause complications like chest pain (angina) or a heart attack. Inform your doctor before taking Benidipine+nebivolol if you have any medical conditions, such as diabetes (high blood sugar), respiratory problems (asthma, emphysema, bronchitis), circulation problems, pheochromocytoma (a tumour of the adrenal gland), or thyroid, liver, kidney, or heart problems. Please consult your doctor before taking Benidipine+nebivolol if you are pregnant or planning to become pregnant. Avoid breastfeeding while using Benidipine+nebivolol, as it contains Nebivolol, which may pass into breast milk and harm the baby. Benidipine+nebivolol may cause dizziness and sleepiness, so avoid driving or operating machines until you are mentally alert.
Drug Interactions
Drug-Drug Interactions: Benidipine+nebivolol may interact with certain medications, such as antihypertensives (reserpine, clonidine, verapamil, diltiazem), water pills (chlorthalidone, indapamide, furosemide, hydrochlorothiazide), antiulcer agents (cimetidine), bronchodilators (epinephrine), antiarrhythmics (digoxin), and other beta-blockers (atenolol, bisoprolol, metoprolol, sotalol).
Drug-Food Interactions: Benidipine+nebivolol should not be taken with grape juice, as it may decrease the drug's absorption. Avoid a diet high in salt, fat, and cholesterol while taking Benidipine+nebivolol. Avoid alcohol consumption while taking Benidipine+nebivolol, as it may increase dizziness and could lower blood pressure than normal.
Drug-Disease Interactions: Avoid taking Benidipine+nebivolol if you have any severe liver disease or heart problems, such as heart failure, sick sinus syndrome (a heart rhythm disorder), second- or third-degree heart block, severe bradycardia (very slow heartbeats), and cardiogenic shock (a medical emergency where the heart suddenly fails to pump enough blood to vital organs).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended to avoid alcohol consumption while taking Benidipine+nebivolol to avoid unpleasant side effects. Alcohol intake may cause increased dizziness and also might lower blood pressure than normal.
Pregnancy
cautionPlease consult your doctor before taking Benidipine+nebivolol if you are pregnant or planning to become pregnant. Your doctor will prescribe you Benidipine+nebivolol only if the benefits outweigh the risks.
Breast Feeding
unsafeIt is not recommended to take Benidipine+nebivolol while you are breastfeeding, as it contains Nebivolol, which may pass into breast milk and harm the baby.
Driving
cautionBenidipine+nebivolol may cause dizziness and sleepiness. Therefore, avoid driving or operating machines until you are mentally alert.
Liver
cautionBenidipine+nebivolol should be used with caution in patients with liver impairment. Please consult your doctor if you have a history of liver disease. Your doctor may have to adjust the dose of Benidipine+nebivolol based on the severity of your condition.
Kidney
cautionBenidipine+nebivolol should be used with caution in patients with kidney impairment. Please consult your doctor if you have a history of kidney disease. Your doctor may have to adjust the dose of Benidipine+nebivolol based on the severity of your condition.
Children
unsafeBenidipine+nebivolol is not recommended for use in children under 12 years, as its efficacy and safety have not been established.
Habit Forming
Diet & Lifestyle Advise
- Maintain a low-salt diet and minimize the consumption of processed foods, as they contain more sodium. Try replacing salt with herbs or spices to add flavour to your food.
- Engage in regular exercise, such as cycling, walking, jogging, dancing, or swimming, for at least 30 minutes per day.
- Chronic stress may also contribute to high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and engage in activities that you enjoy.
- Consider adopting the Dietary Approaches to Stop Hypertension (DASH) diet, which includes foods such as fruits, vegetables, whole grains, poultry, fish, and low-fat dairy.
- Increase your intake of potassium from natural sources, which may help lower blood pressure.
- Try to include omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils, such as olive oil, soybean oil, canola oil, and coconut oil, which may help lower high blood pressure.
- Quit smoking and avoid alcohol consumption.
Special Advise
- Regularly monitor blood pressure, blood sugar, heart rate, kidney, and liver function.
- Get up slowly while rising from a lying or sitting position, as Benidipine+nebivolol may cause dizziness.
- Benidipine+nebivolol should be taken at the same time every day to maximize its effects and improve compliance.
Patients Concern
Disease/Condition Glossary
Hypertension: It is a chronic (lifelong) condition in which the blood pressure (BP) against the artery walls becomes very high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. You can have high BP for years without any symptoms. The ideal BP is between 90/60 mm Hg and 120/80 mm Hg. Hypertension is typically defined as BP above 140/90 mm Hg and is considered severe if it exceeds 180/120 mm Hg. Raised BP can lead to complications such as chest pain (angina), heart attack (when the blood supply to the heart is blocked), brain damage (stroke), and kidney failure.
FAQs
Benidipine+nebivolol is used to treat hypertension (high blood pressure).
Benidipine+nebivolol contains two medications: Benidipine (a calcium channel blocker) and Nebivolol (a beta-blocker). Benidipine works by blocking calcium from entering the smooth muscle cells of blood vessels, which helps widen the blood vessels and reduce pressure on them, making it easier for the heart to pump more blood throughout the body. Nebivolol works by blocking beta-1 receptors in the heart, which slows the heart rate and relaxes blood vessels, thereby improving blood flow and lowering blood pressure. Together, Benidipine+nebivolol effectively treats high blood pressure.
Benidipine+nebivolol may cause common side effects, such as headache, nausea, dizziness, fatigue (tiredness), hypotension (low blood pressure), bradycardia (slow heartbeat), palpitation (irregular heartbeats), oedema (swelling), and stomach pain in some cases. Most of these side effects will resolve gradually over time without requiring medical attention. However, if you experience any of these side effects persistently, please consult your doctor.
Yes, Benidipine+nebivolol may cause ankle swelling. Please try to keep your feet elevated when sitting for long hours. If the problem persists, consult your doctor and follow their advice.
If you have diabetes, you should monitor your blood glucose levels often as Benidipine+nebivolol might mask hypoglycaemia (low glucose level) symptoms. However, please consult your doctor before taking Benidipine+nebivolol if you have diabetes.
You are advised to consult your doctor before taking Benidipine+nebivolol if you are pregnant or planning to become pregnant.
No, do not stop taking Benidipine+nebivolol even if you feel better, as discontinuing it suddenly may raise your blood pressure. Therefore, please consult your doctor before making any changes to your dosage schedule.