I understand how uncomfortable this is, but scabies is completely curable. The most effective treatment is prescription permethrin 5% cream, applied from the neck down and washed off after 8 to 14 hours, typically repeated in one week. Alternatively, your doctor may prescribe oral ivermectin. To help with the severe itching, you can use over-the-counter antihistamines or a mild steroid cream, though some itching may temporarily persist even after the mites are gone. Finally, ensure close contacts are treated and wash all bedding and clothes in hot water. Please consult a healthcare professional for a proper prescription.

Since Permethrin (including Lupiscab) has not worked after multiple applications, you may be dealing with permethrin resistance, re-infestation, or post-scabetic dermatitis (irritation from overusing the medication). Please consult a dermatologist immediately. You likely need oral Ivermectin, a highly effective prescription pill for resistant scabies, which is sometimes combined with alternative topical treatments like sulfur ointment. It is crucial that all household members are treated simultaneously, and all bedding and clothing are washed in hot water (above 60?C) to prevent re-infection. Stop applying permethrin without medical supervision, as it can cause severe itching that mimics the infection.