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compositionComposition:CALCITRIOL-0.25MCG
prescriptionPrescription Medicine
Iwitrol Tablet 10's

Iwitrol Tablet is used to treat low blood calcium levels. It contains Calcitriol, which raises Vitamin D levels and thereby increases calcium levels in the blood. In some cases, this medicine may cause side effects such as stomach upset, nausea, vomiting, loss of appetite, mood changes, weakness, tiredness, and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CALCITRIOL-0.25MCG

Manufacturer/Marketer :

Ponoogun Healthcare Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Iwitrol Tablet

Iwitrol Tablet is primarily used to treat low blood calcium levels. It effectively treats various conditions, such as vitamin D deficiency, osteoporosis (characterised by weak bones), and latent tetany (a muscle disease associated with low blood calcium levels). Additionally, Iwitrol Tablet is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people with chronic kidney disease, surgery, or other conditions.

Iwitrol Tablet contains Calcitriol (Vitamin D3). Calcitriol is a synthetic version of Vitamin D3. It raises Vitamin D levels and thereby increases calcium levels in the blood. This helps in improving the absorption rate of calcium from the intestine.

In some cases, Iwitrol Tablet can cause side effects like constipation, stomach upset, nausea, vomiting, loss of appetite, mood changes, weakness, tiredness, fast or pounding heartbeat, bone/muscle pain, and headache. Most of these side effects of Iwitrol Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Take Iwitrol Tablet as prescribed by your doctor. Depending on your medical condition, you are advised to take Iwitrol Tablet for as long as your doctor has prescribed it for you. Iwitrol Tablet can be taken with or without food. Do not chew, bite or break the medicine.

Inform your physician if you are allergic to Iwitrol Tablet . Let your doctor know if you have any liver/kidney disease, heart disease, kidney stones and hypervitaminosis D (having too much vitamin D) hypercalcaemia (high calcium levels), hypervitaminosis D (high vitamin D levels), heart, kidney, liver, or blood vessel diseases, kidney stones, or malabsorption syndrome (difficulty absorbing nutrients from food) before starting Iwitrol Tablet . Pregnant or breastfeeding women should consult their doctor before taking Iwitrol Tablet .

Uses of Iwitrol Tablet

Iwitrol Tablet is used to treat conditions caused by low levels of calcium and vitamin D in the body. The detailed uses of Iwitrol Tablet are as follows:

  • Postmenopausal osteoporosis: Iwitrol Tablet strengthens bones and reduces the risk of fractures in women after menopause.
  • Steroid-induced osteoporosis: Iwitrol Tablet is used to prevent bone thinning in individuals taking long-term oral corticosteroids.
  • Osteomalacia/Rickets: Iwitrol Tablet helps to strengthen weak bones by enhancing calcium and phosphate absorption.
  • Hypoparathyroidism: Iwitrol Tablet manages low parathyroid hormone levels by regulating calcium levels.

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Directions for Use

  • Take Iwitrol Tablet with or without food as advised by your doctor.
  • It is advised to take Iwitrol Tablet once daily; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow Iwitrol Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Key Benefits

  • Iwitrol Tablet offers several medicinal benefits by helping to maintain strong and healthy bones through the prevention and treatment of calcium and vitamin D deficiencies.
  • It reduces the risk of fractures, particularly in individuals with weakened bones such as those affected by osteoporosis.
  • Iwitrol Tablet supports proper bone growth in children and adolescents and aids in managing various bone disorders, such as rickets and osteomalacia.
  • It also helps relieve muscle cramps caused by low calcium levels and improves vitamin D status, which is important for immune function and overall bone health.
  • It is an essential nutrient to maintain bone formation and maintenance.

How Iwitrol Tablet Works

Iwitrol Tablet contains Calcitriol (Vitamin D3); it is used to prevent or treat a calcium deficiency. It is an essential nutrient to maintain bone formation and maintenance. Calcitriol is a synthetic version of Vitamin D3 and treats calcium deficiency with hypoparathyroidism (the parathyroid gland's decreased activity) and metabolic bone diseases in people with chronic kidney failure. It raises Vitamin D levels and thereby increases calcium levels in the blood. This helps in improving the absorption rate of calcium from the intestine.

Storage

Store in a cool and dry place away from sunlight
Side effects of Iwitrol Tablet
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Reduce sodium intake to minimize calcium excretion in urine.
  • Limit animal protein consumption to decrease urinary calcium levels.
  • Increase fluid intake by drinking plenty of water to dilute urine.
  • Moderate calcium intake based on individual needs, avoiding drastic restriction.
  • Limit oxalate-rich foods like spinach and chocolate to minimize kidney stone formation.
  • Stay hydrated by drinking plenty of water.
  • Consider reducing vitamin D supplementation if excessive intake is contributing to hypercalciuria.
  • Regularly monitor urine calcium levels through 24-hour urine tests.
  • Always seek guidance from a healthcare expert prior to implementing substantial changes to your diet or lifestyle routine.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Stay hydrated by drinking plenty of water.
  • Avoid dairy product such as cheese, milk, yogurt and ice cream.
  • Maintain healthy weight and exercise daily.
  • Following a low-calcium diet can help reduce hypercalcemia symptoms.

What if I have taken an overdose of Iwitrol Tablet

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include feeling tired, difficulty thinking clearly, loss of appetite, nausea, vomiting, constipation, increased thirst, increased urination, weight loss, weakness, headache, upset stomach, dry mouth, muscle or bone pain, metallic taste in the mouth, difficult or painful urination, changes in vision, hallucination (seeing things or hearing voices that do not exist), fever or chills, stomach pain, pale/fatty stools, yellowing of the skin or eyes, runny nose, decreased sexual desire, and irregular heartbeat. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Avoid taking Iwitrol Tablet if you are allergic to it.
  • Before taking Iwitrol Tablet , inform your doctor if you are undergoing hemodialysis due to kidney problems and have a stent in the heart.
  • Iwitrol Tablet may alter calcium levels, so it is recommended to monitor calcium levels in the blood and urine regularly.
  • Inform your doctor immediately if you notice fever, increased thirst and urination, dehydration, bedwetting, constipation, and stomach pain, as they may be signs of very high calcium levels in your blood.
  • Pregnant or breastfeeding women should consult their doctor before taking Iwitrol Tablet .
  • Higher doses of vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor.
  • Do not take Iwitrol Tablet if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), or malabsorption syndrome (difficulty absorbing nutrition from food).

Drug-Drug Interactions

verifiedApollotooltip
CalcitriolDihydrotachysterol
Severe
CalcitriolParicalcitol
Severe

Drug-Drug Interactions

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CalcitriolDihydrotachysterol
Severe
How does the drug interact with Iwitrol Tablet:
Co-administration of Iwitrol Tablet with Dihydrotachysterol can increase the risk of adverse effects.

How to manage the interaction:
Co-administration of Dihydrotachysterol with Iwitrol Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, throwing up, constipation, dry mouth, strange taste in your mouth, muscle or bone pain, trouble coordinating movements, weak muscles, peeing a lot, feeling very thirsty, losing weight, eye infection, sensitivity to light, itching, or a higher body temperature - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
CalcitriolParicalcitol
Severe
How does the drug interact with Iwitrol Tablet:
Co-administration of Paricalcitol and Iwitrol Tablet are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to excessive calcium levels in the blood and urine.

How to manage the interaction:
Concomitant use of Paricalcitol with Iwitrol Tablet can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolFosphenytoin
Severe
How does the drug interact with Iwitrol Tablet:
Taking Iwitrol Tablet with Fosphenytoin can reduce the levels and efficacy of Iwitrol Tablet.

How to manage the interaction:
Taking Iwitrol Tablet with Fosphenytoin together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms of sudden dizziness, weakness, chest pain or pressure, abnormal body movements, uncontrollable eye movements, itching, burning, or tingling sensation, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
CalcitriolCalcifediol
Severe
How does the drug interact with Iwitrol Tablet:
Co-administration of Calcifediol and Iwitrol Tablet are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Taking Calcifediol with Iwitrol Tablet can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, headache, fatigue, drowsiness, vertigo, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolDigitoxin
Severe
How does the drug interact with Iwitrol Tablet:
Co-administration of Iwitrol Tablet with Digitoxin may increase the risk or severity of digitoxin toxicity and irregular heart rhythm.

How to manage the interaction:
Although there is an interaction, Iwitrol Tablet can be taken with Digitoxin if prescribed by the doctor. Consult the prescriber if you experience symptoms that could indicate high blood calcium, such as weakness, fatigue, headache, dizziness, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, a metallic taste in the mouth, bone or muscle pain, incoordination, frequent urination, and weight loss. Also, seek medical attention if you experience symptoms of digitoxin toxicity, such as blurred vision, slow pulse, or irregular heartbeats. Do not discontinue the medication without consulting a doctor.
CalcitriolErgocalciferol
Severe
How does the drug interact with Iwitrol Tablet:
Co-administration of Ergocalciferol and Iwitrol Tablet are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Co-administration of Ergocalciferol with Iwitrol Tablet can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolColecalciferol
Severe
How does the drug interact with Iwitrol Tablet:
Co-administration of Cholecalciferol and Iwitrol Tablet are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between colecalciferol and Iwitrol Tablet, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
CalcitriolCarbamazepine
Severe
How does the drug interact with Iwitrol Tablet:
Co-administration of Iwitrol Tablet with Carbamazepine may decrease the effects of Iwitrol Tablet.

How to manage the interaction:
Although there is an interaction, Iwitrol Tablet can be taken with Carbamazepine if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
CalcitriolMetolazone
Severe
How does the drug interact with Iwitrol Tablet:
Co-administration of Metolazone with Iwitrol Tablet can cause blood calcium levels to become too high.

How to manage the interaction:
Although there is an interaction, Iwitrol Tablet can be taken with metolazone if prescribed by the doctor. Consult the doctor if you experience symptoms such as dizziness, drowsiness, weakness, lethargy, headache, nausea, vomiting, or seizures. Do not discontinue the medication without consulting a doctor.
CalcitriolAmobarbital
Severe
How does the drug interact with Iwitrol Tablet:
Co-administration of Amobarbital and Iwitrol Tablet may decrease the effects of Iwitrol Tablet.

How to manage the interaction:
Co-administration of Iwitrol Tablet with Amobarbital can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include dairy products like milk, yoghurt, cheese, or milk-based custard in your diet.
  • Eat a serving of broccoli, cabbage, bok choy, spinach, and other green leafy vegetables daily.
  • Snack on calcium-rich nuts like Brazil nuts or almonds.
  • Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
  • Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
  • Replace the meat with tofu or tempeh for extra calcium in your food.

Habit Forming

No

Therapeutic Class

[MULTIMINERALS]

All Substitutes & Brand Comparisons

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Alcohol

Caution

Drinking alcohol can affect calcium absorption; hence, it is advised to limit the alcohol intake while using Iwitrol Tablet .

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Pregnancy

Consult your doctor

Use higher doses of Iwitrol Tablet during pregnancy than the daily dietary allowance only when the doctor advises. Calcitriol in higher doses may harm the fetus. Your doctor will weigh the potential risks and benefits before prescribing Iwitrol Tablet .

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Breast Feeding

Consult your doctor

Consult your doctor before taking Iwitrol Tablet if you are breastfeeding. Iwitrol Tablet can pass into the breast milk. If Iwitrol Tablet is used during breastfeeding, please monitor the mother and the infant's serum calcium levels.

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Driving

Safe if prescribed

Iwitrol Tablet may not affect your ability to drive.

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Liver

Caution

Before taking $ name, let your doctor know if you have any history of liver disease. Hepatic impairment/liver disease can alter the metabolic and therapeutic activity of certain Vitamin D forms.

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Kidney

Caution

It is advised to seek a doctor's advice before starting Iwitrol Tablet if you have kidney diseases like kidney stones or are undergoing dialysis. Calcitriol in Iwitrol Tablet increases inorganic phosphate levels in serum; hence, caution should be taken in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition).

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Children

Caution

Iwitrol Tablet should be used with caution in children and only if prescribed by a doctor.

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Heart

Consult your doctor

Let your physician know if you have any pre-existing heart problems.

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Geriatrics

Consult your doctor

Limited information available for use of Iwitrol Tablet in elderly patients. Please consult your doctor.

FAQs

Iwitrol Tablet belongs to a group of medicines called vitamin D metabolites primarily used to treat low blood calcium levels. Iwitrol Tablet effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels).

Iwitrol Tablet contains calcitriol, which works by helping the body absorb more calcium from the diet. This helps to form healthy bones and reduce bone damage.

Iwitrol Tablet can cause kidney stones due to excess calcium deposition when used for a prolonged period. Please consult your doctor before taking Iwitrol Tablet as a daily supplement if you have any kidney problems or a history of kidney stones.

Iwitrol Tablet is used to increase low calcium levels in the body. Hence, it is not advised to use Iwitrol Tablet during hypercalcemia since it causes an overdose of calcium, leading to kidney stones and other effects.

Do not use Iwitrol Tablet if you are allergic to any of the ingredients in Iwitrol Tablet . It is not recommended in hypercalcemia (high calcium levels), metastatic calcification (extra deposits of calcium in the body), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food).

Country of origin

India

Manufacturer/Marketer address

Shop No 102-103, Plot No. 1, Sector-6 Lsc, Vardhman Key Point
Other Info - IWI0008

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