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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Atranza 10 mg Capsule 100's belongs to a class of drugs called retinoids which is used in the treatment of acne. This medicine works by inhibiting the acne-causing microbes and unblocks pores. Common side effects include dryness of skin, redness, skin irritation, pain or skin flaking.

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Whats That

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Composition :

TRETINOIN-10MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Atranza 10 mg Capsule 100's

Atranza 10 mg Capsule 100's belongs to a class of drugs called retinoids (similar to vitamin A). Atranza 10 mg Capsule 100's is used to treat acute promyelocytic leukaemia (a type of blood problem). Acute promyelocytic leukaemia is a blood cancer that causes a marked increase in a type of immature white blood cells known as promyelocytes in the blood and bone marrow. 

Atranza 10 mg Capsule 100's contains Tretinoin, a form of vitamin A that works by reducing the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.

Take Atranza 10 mg Capsule 100's as prescribed. Your doctor will advise you how often you need to take Atranza 10 mg Capsule 100's based on your medical condition. Some people may experience dizziness, headache, feeling tired, stomach pain, irregular heartbeat, hair loss, bone or joint pain, dry skin and changes in eyesight or hearing. Most of these side effects of Atranza 10 mg Capsule 100's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Tretinoin, peanuts, soya or any other ingredients in Atranza 10 mg Capsule 100's, please tell your doctor. Avoid taking Atranza 10 mg Capsule 100's if you are pregnant as it may harm the foetus. Avoid breastfeeding while taking Atranza 10 mg Capsule 100's as it is excreted into breast milk and may harm the baby. Avoid taking Atranza 10 mg Capsule 100's if you are taking other retinoid medicines (acitretin, tazarotene, isotretinoin), vitamin A and tetracyclines (antibiotics). If you are allergic to any sugars, please inform your doctor before taking Atranza 10 mg Capsule 100's as it may contain sorbitol.

Uses of Atranza 10 mg Capsule 100's

Atranza 10 mg Capsule 100's is used in the treatment of acute promyelocytic leukaemia. The detailed use of Atranza 10 mg Capsule 100's is as follows:<br/>• Treatment of Acute promyelocytic leukaemia: Atranza 10 mg Capsule 100's is used to treat Acute Promyelocytic Leukemia (APL), a type of blood cancer, by helping abnormal blood cells mature and become normal, reducing the risk of bleeding and improving blood counts, ultimately promoting effective treatment and management of the condition.<br/>

Directions for Use

• Atranza 10 mg Capsule 100's can be taken with meals to reduce any potential stomach upset and to improve absorption.• It is advised to take Atranza 10 mg Capsule 100's twice daily; however, follow your doctor's recommendation regarding the dosage and duration.• Swallow the medicine as a whole with water.• Do not break, crush or chew it.

Medicinal Benefits

Atranza 10 mg Capsule 100's is a form of vitamin A that is primarily used to treat acute promyelocytic leukaemia (a type of blood problem). Atranza 10 mg Capsule 100's reduces the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.  

How Atranza 10 mg Capsule 100's Works

Atranza 10 mg Capsule 100's contains Tretinoin, a form of vitamin A that works by reducing the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Atranza 10 mg Capsule 100's out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Atranza 10 mg Capsule
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.

What if I have taken an overdose of Atranza 10 mg Capsule 100's

Never take more than the prescribed dose. Atranza 10 mg Capsule 100's overdose symptoms can include redness, headache, flushing, stomach pain, dizziness, and loss of coordination in addition to cracked and sore lips. Seek immediate medical help if an overdose is suspected.

Drug Warnings

If you are allergic to Tretinoin, peanuts, soya or any other ingredients, please tell your doctor. Avoid taking Atranza 10 mg Capsule 100's if you are pregnant as it may harm the foetus. Avoid breastfeeding while taking Atranza 10 mg Capsule 100's as it is excreted into breast milk and may harm the baby. You are advised to use effective contraceptive methods while using Atranza 10 mg Capsule 100's to prevent pregnancy. Avoid taking Atranza 10 mg Capsule 100's if you are taking other retinoid medicines (acitretin, tazarotene, isotretinoin), vitamin A and tetracyclines (antibiotics). If you are allergic to any sugars, please inform your doctor before taking Atranza 10 mg Capsule 100's as it may contain sorbitol.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Atranza 10 mg Capsule:
Coadministration of Atranza 10 mg Capsule with Doxycycline can increase the risk of side effects like vision problems.

How to manage the interaction:
Taking Atranza 10 mg Capsule with Doxycycline is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden headache, nausea, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Atranza 10 mg Capsule:
Coadministration of Atranza 10 mg Capsule with Tetracycline can increase the risk of pseudotumor cerebri(caused by increased pressure in the brain).

How to manage the interaction:
Taking Atranza 10 mg Capsule with Tetracycline is not recommended, but can be taken together if prescribed by a doctor. However, if you experience headache, nausea, vomiting, and visual disturbances contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Atranza 10 mg Capsule:
Co-administration of Atranza 10 mg Capsule with Oxytetracycline can increase the risk of pseudotumor cerebri (caused by increased pressure in the brain).

How to manage the interaction:
Taking Oxytetracycline with Atranza 10 mg Capsule is not recommended as it can be taken if prescribed by a doctor. However, if you experience headaches, nausea, vomiting, and vision problems contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TretinoinDemeclocycline
Critical
How does the drug interact with Atranza 10 mg Capsule:
Combining Atranza 10 mg Capsule with Demeclocycline can increase the risk of side effects like pseudotumor cerebri (increased pressure in the brain)

How to manage the interaction:
Taking Atranza 10 mg Capsule with Demeclocycline is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden headache, nausea, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Atranza 10 mg Capsule:
Co-administration of Atranza 10 mg Capsule with Minocycline can increase the risk of side effects like pseudotumor cerebri (increased pressure in the brain)

How to manage the interaction:
Taking Atranza 10 mg Capsule with Minocycline is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Atranza 10 mg Capsule:
Co-administration of Atranza 10 mg Capsule with tranexamic acid may increase the risk of blood clots.

How to manage the interaction:
Taking Atranza 10 mg Capsule with tranexamic acid is not recommended due to its increased effects, however, it can be taken only if your doctor has advised it. If you experience symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Atranza 10 mg Capsule:
Coadministration of Acitretin with Atranza 10 mg Capsule may increase the risk or severity of hypervitaminosis A (too much vitamin A in the body), increased pressure in the brain, and injury of the liver, pancreas, or digestive tract.

How to manage the interaction:
Although there is a possible interaction between Acitretin and Atranza 10 mg Capsule, you can take these medicines together if prescribed by your doctor. However, if you notice early signs and symptoms of hypervitaminosis A such as inflammation or bleeding of the gums or lips, dry, scaly, itchy, or red skin, hair loss, headache, dizziness, and nausea, contact a doctor immediately. Avoid or limit the consumption of additional vitamin A while taking these medications. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Atranza 10 mg Capsule:
Using Atranza 10 mg Capsule together with Voriconazole may increase the blood levels of Atranza 10 mg Capsule.

How to manage the interaction:
Taking Atranza 10 mg Capsule with Voriconazole together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience headache, visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Atranza 10 mg Capsule:
The blood levels of Atranza 10 mg Capsule may rise when itraconazole and Atranza 10 mg Capsule are taken together, which may lead to pseudotumor cerebri(elevated pressure in the brain).

How to manage the interaction:
Atranza 10 mg Capsule and itraconazole may interact, but if a doctor prescribes them, you can still use them. If you have a headache, nausea, vomiting, blurred vision, sensitivity to light, or ringing in the ears, contact a doctor. Never stop taking a medication without consulting a doctor.
How does the drug interact with Atranza 10 mg Capsule:
Taking Isotretinoin together with Atranza 10 mg Capsule may increase the risk of hypervitaminosis A (excessive vitamin A-related effects).

How to manage the interaction:
Although taking isotretinoin and Atranza 10 mg Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as increased pressure in the brain (headache, nausea, vomiting, visual disturbances) or liver damage (fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, yellowing of the skin or eyes). Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat 5 portions of vegetables and fruits in a day.
  • Reduce the intake of salt and fat.

  • Regular exercise may help to reduce depression and excessive tiredness after treatment.

  • Start with gentle walking and once your white blood cell count comes back to normal, you can go swimming.

  • Avoid alcohol consumption.

Habit Forming

No

Therapeutic Class

RETINOIDS
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Alcohol

Caution

Interaction of alcohol with Atranza 10 mg Capsule 100's is unknown. Please consult a doctor before consuming alcohol while using Atranza 10 mg Capsule 100's.

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Pregnancy

Unsafe

Atranza 10 mg Capsule 100's is Category C pregnancy drug and is considered unsafe for pregnant women as it may harm the unborn baby.

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Breast Feeding

Unsafe

Atranza 10 mg Capsule 100's is excreted into breast milk and may harm the baby. Therefore, you are recommended to avoid breastfeeding while taking Atranza 10 mg Capsule 100's.

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Driving

Caution

Atranza 10 mg Capsule 100's may cause dizziness or severe headache. Therefore, drive only if you alert after taking Atranza 10 mg Capsule 100's.

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Liver

Caution

Take Atranza 10 mg Capsule 100's with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Atranza 10 mg Capsule 100's with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Atranza 10 mg Capsule 100's should be given to children only in doses advised by the doctor.

Have a query?

FAQs

Atranza 10 mg Capsule 100's belongs to a class of drugs called retinoids (similar to vitamin A). Atranza 10 mg Capsule 100's is used to treat acute promyelocytic leukaemia (a type of blood problem).

Atranza 10 mg Capsule 100's works by reducing the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.

You are recommended to avoid pregnancy while taking Atranza 10 mg Capsule 100's and for 1 month after stopping treatment with Atranza 10 mg Capsule 100's as it may cause the birth of the deformed baby. Therefore, you are advised to use effective contraceptive measures while taking Atranza 10 mg Capsule 100's and for 1 month after stopping treatment with Atranza 10 mg Capsule 100's to prevent pregnancy. Also, women using Atranza 10 mg Capsule 100's should take a pregnancy test every month and if you become pregnant while taking Atranza 10 mg Capsule 100's, inform your doctor immediately.

Atranza 10 mg Capsule 100's may cause dizziness as a temporary side effect. Therefore, drive only if you are alert after taking Atranza 10 mg Capsule 100's.

You are not recommended to take low-dose progestogens (mini pill) with Atranza 10 mg Capsule 100's as their effectiveness may be reduced. However, discuss with your doctor if you have any concerns regarding this so that a different oral contraceptive may be prescribed.

Atranza 10 mg Capsule 100's may cause painful swelling in the leg in a few patients. If you experience painful swelling in your leg, difficulty breathing or sudden chest pain while taking Atranza 10 mg Capsule 100's, please inform your doctor immediately as these might be signs of a blood clot.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ATR0123

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