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compositionComposition:TRETINOIN-10MG
prescriptionPrescription Medicine
Atranza Capsule

Atranza Capsule belongs to a class of drugs called retinoids which is used in the treatment of acne. This medicine works by inhibiting the acne-causing microbes and unblocks pores. Common side effects include dryness of skin, redness, skin irritation, pain or skin flaking.

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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

TRETINOIN-10MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Atranza Capsule

Atranza Capsule belongs to a class of drugs called retinoids (similar to vitamin A). Atranza Capsule is used to treat acute promyelocytic leukaemia (a type of blood problem). Acute promyelocytic leukaemia is a blood cancer that causes a marked increase in a type of immature white blood cells known as promyelocytes in the blood and bone marrow. 

Atranza Capsule contains Tretinoin, a form of vitamin A that works by reducing the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.

Take Atranza Capsule as prescribed. Your doctor will advise you how often you need to take Atranza Capsule based on your medical condition. Some people may experience dizziness, headache, feeling tired, stomach pain, irregular heartbeat, hair loss, bone or joint pain, dry skin and changes in eyesight or hearing. Most of these side effects of Atranza Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Tretinoin, peanuts, soya or any other ingredients in Atranza Capsule, please tell your doctor. Avoid taking Atranza Capsule if you are pregnant as it may harm the foetus. Avoid breastfeeding while taking Atranza Capsule as it is excreted into breast milk and may harm the baby. Avoid taking Atranza Capsule if you are taking other retinoid medicines (acitretin, tazarotene, isotretinoin), vitamin A and tetracyclines (antibiotics). If you are allergic to any sugars, please inform your doctor before taking Atranza Capsule as it may contain sorbitol.

Uses of Atranza Capsule

Atranza Capsule is used in the treatment of acute promyelocytic leukaemia. The detailed use of Atranza Capsule is as follows:

  • Treatment of Acute promyelocytic leukaemia: Atranza Capsule is used to treat Acute Promyelocytic Leukemia (APL), a type of blood cancer, by helping abnormal blood cells mature and become normal, reducing the risk of bleeding and improving blood counts, ultimately promoting effective treatment and management of the condition.

Key Benefits

Atranza Capsule is a form of vitamin A that is primarily used to treat acute promyelocytic leukaemia (a type of blood problem). Atranza Capsule reduces the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.  

Side effects of Atranza Capsule
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

Directions for Use

  • Atranza Capsule can be taken with meals to reduce any potential stomach upset and to improve absorption.
  • It is advised to take Atranza Capsule twice daily; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow the medicine as a whole with water.
  • Do not break, crush, or chew it.

How Atranza Capsule Works

Atranza Capsule contains Tretinoin, a form of vitamin A that works by reducing the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.
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Alcohol

Caution

Interaction of alcohol with Atranza Capsule is unknown. Please consult a doctor before consuming alcohol while using Atranza Capsule.

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Pregnancy

Unsafe

Atranza Capsule is Category C pregnancy drug and is considered unsafe for pregnant women as it may harm the unborn baby.

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Breast Feeding

Unsafe

Atranza Capsule is excreted into breast milk and may harm the baby. Therefore, you are recommended to avoid breastfeeding while taking Atranza Capsule.

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Driving

Caution

Atranza Capsule may cause dizziness or severe headache. Therefore, drive only if you alert after taking Atranza Capsule.

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Liver

Caution

Take Atranza Capsule with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Atranza Capsule with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Atranza Capsule should be given to children only in doses advised by the doctor.

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Heart

Consult your doctor

Please consult your doctor before using Atranza Capsule if you have pre-existing heart problems. Your doctor will prescribe Atranza Capsule if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Atranza Capsule to geriatric patients. Your doctor will prescribe Atranza Capsule if the benefits outweigh the risks.

What if I have taken an overdose of Atranza Capsule

Never take more than the prescribed dose. Atranza Capsule overdose symptoms can include redness, headache, flushing, stomach pain, dizziness, and loss of coordination in addition to cracked and sore lips. Seek immediate medical help if an overdose is suspected.

Diet & Lifestyle Advise

  • Eat 5 portions of vegetables and fruits in a day.

  • Reduce the intake of salt and fat.

  • Regular exercise may help to reduce depression and excessive tiredness after treatment.

  • Start with gentle walking and once your white blood cell count comes back to normal, you can go swimming.

  • Avoid alcohol consumption.

Have a query?

How Soon It Starts Working

The time required for Atranza Capsule to start to work: The time required for Atranza Capsule to show its action is unknown. The time for which the effects of Atranza Capsule last: The duration of action for Atranza Capsule is unknown.

What if you forget to take Atranza Capsule

If you miss a dose of Atranza Capsule, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep Atranza Capsule out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

If you are allergic to Tretinoin, peanuts, soya or any other ingredients, please tell your doctor. Avoid taking Atranza Capsule if you are pregnant as it may harm the foetus. Avoid breastfeeding while taking Atranza Capsule as it is excreted into breast milk and may harm the baby. You are advised to use effective contraceptive methods while using Atranza Capsule to prevent pregnancy. Avoid taking Atranza Capsule if you are taking other retinoid medicines (acitretin, tazarotene, isotretinoin), vitamin A and tetracyclines (antibiotics). If you are allergic to any sugars, please inform your doctor before taking Atranza Capsule as it may contain sorbitol.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interaction: Atranza Capsule may interact with antibiotics (erythromycin, clarithromycin, rifampicin, tetracyclines), vitamin A, retinoids, low-dose progestogens, antifungal (ketoconazole, itraconazole, posaconazole, fluconazole), corticosteroids (dexamethasone, prednisolone), anticonvulsants (phenobarbital), anti-HIV medicines (saquinavir, ritonavir), heart-related medicines (diltiazem, verapamil), drugs for stomach ulcers (cimetidine), immunosuppressant (ciclosporin) and medicines to reduce bleeding (aprotinin, aminocaproic acid, tranexamic acid).

Drug-Food Interaction: No interactions found. 

Drug-Disease Interaction: If you have ever had any mental health problems including mood changes, depression or aggressive tendencies, inform your doctor before taking Atranza Capsule.

TretinoinDoxycycline
Critical
TretinoinOxytetracycline
Critical

Drug-Drug Interactions

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TretinoinDoxycycline
Critical
How does the drug interact with Atranza Capsule:
Coadministration of Atranza Capsule with Doxycycline can increase the risk of side effects like vision problems.

How to manage the interaction:
Taking Atranza Capsule with Doxycycline is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden headache, nausea, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TretinoinOxytetracycline
Critical
How does the drug interact with Atranza Capsule:
Co-administration of Atranza Capsule with Oxytetracycline can increase the risk of pseudotumor cerebri (caused by increased pressure in the brain).

How to manage the interaction:
Taking Oxytetracycline with Atranza Capsule is not recommended as it can be taken if prescribed by a doctor. However, if you experience headaches, nausea, vomiting, and vision problems contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TretinoinTetracycline
Critical
How does the drug interact with Atranza Capsule:
Coadministration of Atranza Capsule with Tetracycline can increase the risk of pseudotumor cerebri(caused by increased pressure in the brain).

How to manage the interaction:
Taking Atranza Capsule with Tetracycline is not recommended, but can be taken together if prescribed by a doctor. However, if you experience headache, nausea, vomiting, and visual disturbances contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TretinoinMinocycline
Critical
How does the drug interact with Atranza Capsule:
Co-administration of Atranza Capsule with Minocycline can increase the risk of side effects like pseudotumor cerebri (increased pressure in the brain)

How to manage the interaction:
Taking Atranza Capsule with Minocycline is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TretinoinDemeclocycline
Critical
How does the drug interact with Atranza Capsule:
Combining Atranza Capsule with Demeclocycline can increase the risk of side effects like pseudotumor cerebri (increased pressure in the brain)

How to manage the interaction:
Taking Atranza Capsule with Demeclocycline is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden headache, nausea, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TretinoinIsotretinoin
Severe
How does the drug interact with Atranza Capsule:
Taking Isotretinoin together with Atranza Capsule may increase the risk of hypervitaminosis A (excessive vitamin A-related effects).

How to manage the interaction:
Although taking isotretinoin and Atranza Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as increased pressure in the brain (headache, nausea, vomiting, visual disturbances) or liver damage (fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, yellowing of the skin or eyes). Do not stop using any medications without consulting doctor.
TretinoinAcitretin
Severe
How does the drug interact with Atranza Capsule:
Coadministration of Acitretin with Atranza Capsule may increase the risk or severity of hypervitaminosis A (too much vitamin A in the body), increased pressure in the brain, and injury of the liver, pancreas, or digestive tract.

How to manage the interaction:
Although there is a possible interaction between Acitretin and Atranza Capsule, you can take these medicines together if prescribed by your doctor. However, if you notice early signs and symptoms of hypervitaminosis A such as inflammation or bleeding of the gums or lips, dry, scaly, itchy, or red skin, hair loss, headache, dizziness, and nausea, contact a doctor immediately. Avoid or limit the consumption of additional vitamin A while taking these medications. Do not discontinue any medication without consulting a doctor.
TretinoinItraconazole
Severe
How does the drug interact with Atranza Capsule:
The blood levels of Atranza Capsule may rise when itraconazole and Atranza Capsule are taken together, which may lead to pseudotumor cerebri(elevated pressure in the brain).

How to manage the interaction:
Atranza Capsule and itraconazole may interact, but if a doctor prescribes them, you can still use them. If you have a headache, nausea, vomiting, blurred vision, sensitivity to light, or ringing in the ears, contact a doctor. Never stop taking a medication without consulting a doctor.
TretinoinLeflunomide
Severe
How does the drug interact with Atranza Capsule:
Co-administration of leflunomide and Atranza Capsule can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Atranza Capsule and leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TretinoinVoriconazole
Severe
How does the drug interact with Atranza Capsule:
Using Atranza Capsule together with Voriconazole may increase the blood levels of Atranza Capsule.

How to manage the interaction:
Taking Atranza Capsule with Voriconazole together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience headache, visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[RETINOIDS]

FAQs

Atranza Capsule belongs to a class of drugs called retinoids (similar to vitamin A). Atranza Capsule is used to treat acute promyelocytic leukaemia (a type of blood problem).

Atranza Capsule works by reducing the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.

You are recommended to avoid pregnancy while taking Atranza Capsule and for 1 month after stopping treatment with Atranza Capsule as it may cause the birth of the deformed baby. Therefore, you are advised to use effective contraceptive measures while taking Atranza Capsule and for 1 month after stopping treatment with Atranza Capsule to prevent pregnancy. Also, women using Atranza Capsule should take a pregnancy test every month and if you become pregnant while taking Atranza Capsule, inform your doctor immediately.

Atranza Capsule may cause dizziness as a temporary side effect. Therefore, drive only if you are alert after taking Atranza Capsule.

You are not recommended to take low-dose progestogens (mini pill) with Atranza Capsule as their effectiveness may be reduced. However, discuss with your doctor if you have any concerns regarding this so that a different oral contraceptive may be prescribed.

Atranza Capsule may cause painful swelling in the leg in a few patients. If you experience painful swelling in your leg, difficulty breathing or sudden chest pain while taking Atranza Capsule, please inform your doctor immediately as these might be signs of a blood clot.

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Author Details

Veda MaddalaDoctor badge

Written By

  • Veda Maddala

    M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

  • Santoshini Reddy G

    M Pharmacy

Last Updated

Doctor imageWe provide you with authentic, trustworthy and relevant information

Manufacturer/Marketer address

50Th K.M. Stone, Nh-1, Murthal, Sonepat
Other Info - AT86036
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