For temporary relief of acute ankle and neck pain, you can use over-the-counter pain relievers. Acetaminophen is effective for pain management, while nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen can help reduce both pain and inflammation. Please take these with food to protect your stomach. Additionally, applying ice packs to your ankles and a warm compress to your neck can provide comfort. Because pain in multiple joints can sometimes indicate an underlying issue, I highly recommend consulting a doctor for a proper evaluation. Seek immediate medical care if you experience weakness, numbness, tingling in your limbs, or difficulty walking.