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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Zyflur 0.03% Eye Drop 5 ml contains flurbiprofen which is an NSAID (Non-Steroidal Anti-Inflammatory Drugs) medicine. It is used to control eye inflammation before and after eye surgery (such as cataract removal) and laser surgery. This medicine helps prevent pupil of the eye from narrowing. It also prevents intraoperative miosis (decreased pupil size) during surgery.
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Manufacturer/Marketer :

Zytras Life Sciences Pvt Ltd

Consume Type :

OPHTHALMIC

Return Policy :

Not Returnable

Expires on or after :

About Zyflur 0.03% Eye Drop 5 ml

Zyflur 0.03% Eye Drop 5 ml belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs) used to control eye inflammation before and after eye surgery (such as cataract removal) and laser surgery. It also prevents intraoperative miosis (decreased pupil size) during surgery.

Zyflur 0.03% Eye Drop 5 ml is composed of Flurbiprofen, an ophthalmic anti-inflammatory agent. It works by preventing the pupil of the eye from narrowing, thus making it easier to examine the eye, remove the cataract and replace a new lens by the doctor. It is also used to relieve eye pain and inflammation after surgery.

Zyflur 0.03% Eye Drop 5 ml is for ophthalmic (for the eye) use only. Common side effects of Zyflur 0.03% Eye Drop 5 ml include eye redness, irritation, burning or a stinging sensation at the application site, and temporary blurred vision. These side effects may not occur in every patient using this medication and differ individually. If the side effects persist longer or worsen, please seek a doctor's advice.

Tell your doctor if you are allergic to Zyflur 0.03% Eye Drop 5 ml or other medications. Avoid contact of the tip of the dispensing container with the eye, eyelids, fingers, and other surfaces to prevent contamination. If you are pregnant and breastfeeding, inform your doctor before using Zyflur 0.03% Eye Drop 5 ml. This medicine may cause temporary blurred vision; hence drive only when you are alert and have clear vision. Zyflur 0.03% Eye Drop 5 ml should be used in children only if advised by a doctor.

Uses of Zyflur 0.03% Eye Drop 5 ml

Zyflur 0.03% Eye Drop 5 ml is used for the prevention of intraoperative miosis and the treatment of post-operative eye pain and inflammation. The detailed uses of Zyflur 0.03% Eye Drop 5 ml are as follows:

  • Prevents pupil constriction during surgery: Zyflur 0.03% Eye Drop 5 ml helps maintain pupil dilation (prevents miosis) during eye surgeries like cataract procedures, ensuring better surgical visibility.
  • Reduces post-operative eye pain: Zyflur 0.03% Eye Drop 5 ml minimizes discomfort and pain that can occur after eye surgeries.
  • Controls inflammation: Zyflur 0.03% Eye Drop 5 ml helps decrease swelling and inflammation in the eye following surgical procedures, promoting smoother recovery.

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Directions for Use

  • Zyflur 0.03% Eye Drop 5 ml is typically used 1-2 times a day, or as prescribed by your healthcare provider, based on the severity of the condition.
  • Before using eye drops, wash your hands thoroughly. Then, tilt your head back, gently pull down your lower eyelid to create a small pocket, and drop the prescribed number of drops into the affected eye. Close your eye and gently press the corner of your eye near the nose for 1-2 minutes to prevent the drops from draining out.
  • Avoid touching the dropper to any surface, including your eyes, to prevent contamination.

Medicinal Benefits

Zyflur 0.03% Eye Drop 5 ml contains Flurbiprofen which prevents the pupil of the eye from narrowing, thus making it easier for the eye examination to remove the cataract and replace a new lens by the doctor. It is a non-steroidal anti-inflammatory drug that inhibits prostaglandins and maintains intraoperative pupil dilation (widening). It further relieves pain and inflammation of the eye after surgery.

How Zyflur 0.03% Eye Drop 5 ml Works

Zyflur 0.03% Eye Drop 5 ml is composed of Flurbiprofen, an ophthalmic anti-inflammatory agent. It works by preventing the pupil of the eye from narrowing, thus making it easier to examine the eye, remove the cataract and replace a new lens by the doctor. It is also used to relieve eye pain and inflammation after surgery.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Zyflur 0.03% Eye Drop 5 ml

An overdose of Zyflur 0.03% Eye Drop 5 ml may cause stinging or burning of the eyes, and an increase or decrease in pupil size (dark area in the centre of the eye). Use this medicine as prescribed. Seek emergency medical help if an overdose is suspected.

Drug Warnings

If you have allergic reactions to medicines/NSAIDs (sneezing, runny or stuffy nose, or wheezing), asthma, viral eye infections, and bleeding and blood clotting problems, inform your doctor before starting Zyflur 0.03% Eye Drop 5 ml. It is advised to check with your doctor before using Zyflur 0.03% Eye Drop 5 ml if you are pregnant or breastfeeding. Avoid driving or operating machines until you have a clear vision since the administration of Zyflur 0.03% Eye Drop 5 ml may cause temporary blurred vision for a while.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Taking Ketorolac with Zyflur 0.03% Eye Drop 5 ml can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration.

How to manage the interaction:
Taking Zyflur 0.03% Eye Drop 5 ml with Ketorolac is not recommended, but it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Taking Ketorolac with Zyflur 0.03% Eye Drop 5 ml can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration.

How to manage the interaction:
Taking Zyflur 0.03% Eye Drop 5 ml with Ketorolac tromethamine is not recommended, but it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Co-administration of Zyflur 0.03% Eye Drop 5 ml with Lithium may significantly increase the blood levels of lithium.

How to manage the interaction:
There may be a possibility of interaction between Zyflur 0.03% Eye Drop 5 ml and Lithium, but it can be taken if prescribed by a doctor. However, if you experience drowsiness, dizziness, confusion, loose stools, vomiting, muscle weakness, muscle incoordination, shaking of hands and legs, blurred vision, ringing in the ear, excessive thirst and increased urination contact your doctor immediately. Do not stop using any medications without a doctor's advice.
FlurbiprofenValdecoxib
Severe
How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Taking Valdecoxib with Zyflur 0.03% Eye Drop 5 ml can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Although taking Zyflur 0.03% Eye Drop 5 ml and Valdecoxib together can evidently cause an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Taking Warfarin with Zyflur 0.03% Eye Drop 5 ml can increase the risk of bleeding.

How to manage the interaction:
Although taking Zyflur 0.03% Eye Drop 5 ml and Warfarin together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any signs and symptoms of unusual bleeding, like blood in urine, bruising, coughing up or vomiting blood that looks like coffee grounds, or having a severe headache, consult your doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Co-administration of Zyflur 0.03% Eye Drop 5 ml with Meloxicam may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Although taking Zyflur 0.03% Eye Drop 5 ml and Meloxicam together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
FlurbiprofenOmacetaxine mepesuccinate
Severe
How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Taking Zyflur 0.03% Eye Drop 5 ml with Omacetaxine mepesuccinate can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Zyflur 0.03% Eye Drop 5 ml with Omacetaxine mepesuccinate can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience bleeding, slurred speech, confusion, dizziness, black stools, severe headache, weakness, or vomiting contact your doctor right away. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Taking Celecoxib with Zyflur 0.03% Eye Drop 5 ml can increase the risk of gastrointestinal bleeding and ulcers.

How to manage the interaction:
Although there is a interaction between Zyflur 0.03% Eye Drop 5 ml and Celecoxib, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Using piroxicam together with Zyflur 0.03% Eye Drop 5 ml may increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding and ulceration.

How to manage the interaction:
Although there is a possible interaction between Zyflur 0.03% Eye Drop 5 ml and Piroxicam, it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zyflur 0.03% Eye Drop 5 ml:
Taking Zyflur 0.03% Eye Drop 5 ml with Dabigatran etexilate can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although taking Zyflur 0.03% Eye Drop 5 ml and Dabigatran etexilate together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you experience bleeding, feeling dizzy or lightheaded, dark or sticky stools, throwing up blood, severe headache, or feeling weak contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Know your allergy triggers, such as pollen, dust and other factors.
  • Do not rub your eyes even though some ophthalmic drugs make your eye itchy.
  • If you wear contact lenses: Clean and replace contact lenses more often. Never share contact lenses. Always wash your hands before inserting and removing the contact lens. 
  • Avoid staring at digital screens for longer durations. Rest your eyes every 20 minutes.
  • Avoid or limit the intake of alcohol and caffeine.

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

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Alcohol

Caution

There is limited information on how alcohol consumption affects Zyflur 0.03% Eye Drop 5 ml. Please consult your doctor before using Zyflur 0.03% Eye Drop 5 ml.

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Pregnancy

Caution

If you plan to conceive or are already pregnant, inform your doctor before using Zyflur 0.03% Eye Drop 5 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, please consult your doctor before using Zyflur 0.03% Eye Drop 5 ml.

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Driving

Caution

Zyflur 0.03% Eye Drop 5 ml may cause side effects like blurry vision, affecting your driving ability. Do not drive or operate machinery in such cases. Drive only when you are alert and have a clear vision

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Liver

Caution

Let your doctor know if you have any history of liver diseases before instilling Zyflur 0.03% Eye Drop 5 ml.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before instilling Zyflur 0.03% Eye Drop 5 ml.

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Children

Caution

Zyflur 0.03% Eye Drop 5 ml can be used in children only when advised by a doctor.

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Heart

Zyflur 0.03% Eye Drop 5 ml may increase the risk of heart problems. Therefore, please inform your doctor if you have any heart-related problems before using Zyflur 0.03% Eye Drop 5 ml.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Zyflur 0.03% Eye Drop 5 ml to geriatric patients. Your doctor will prescribe Zyflur 0.03% Eye Drop 5 ml if the benefits outweigh the risks.

FAQs

Zyflur 0.03% Eye Drop 5 ml is used to control eye inflammation before and after eye surgery (such as cataract removal) and laser surgery. It also prevents intraoperative miosis (decreased pupil size) during surgery.

Zyflur 0.03% Eye Drop 5 ml consists of Flurbiprofen, which inhibits prostaglandins, and maintains intraoperative pupil dilation. It prevents the pupil of the eye from narrowing, thus making it easier to perform eye surgery.

If you are wearing contact lenses, remove them while using Zyflur 0.03% Eye Drop 5 ml. Also, remember to wash your hands before and after using the medicine to avoid contamination.

If you use other eye ointments/drops along with Zyflur 0.03% Eye Drop 5 ml, it is advised to maintain a gap of at least 5-10 minutes between each medicine. Also, use eye drops before applying any ointments.

Avoid contact of the tip of the dispensing container with fingers, eyes, and eyelids when you use any eye formulation to prevent contamination of the medicine.

Zyflur 0.03% Eye Drop 5 ml should be used for babies only if prescribed by a doctor. Do not give any medicine to babies without consulting a pediatrician.

Zyflur 0.03% Eye Drop 5 ml may cause blurry vision temporarily. However, if this condition persists or worsens, consult your doctor.

No, Zyflur 0.03% Eye Drop 5 ml need not be refrigerated and can be stored at room temperature

Use Zyflur 0.03% Eye Drop 5 ml as frequently as advised by the doctor. Do not take more or less of Zyflur 0.03% Eye Drop 5 ml or more often than prescribed as it may cause unwanted effects. Please, consult the doctor if you do not observe any improvement upon using recommended dosages.

No, Zyflur 0.03% Eye Drop 5 ml is not an antibiotic or a steroid. It belongs to the class of medicines called NSAIDs (Non-steroidal Anti Inflammatory Drugs).

Zyflur 0.03% Eye Drop 5 ml relieves eye pain and inflammation after surgery. However, it should be used only if advised by a doctor.

Let your doctor know if you are allergic to Zyflur 0.03% Eye Drop 5 ml or any other medications. Also, inform them if you are pregnant, breastfeeding, or have a history of allergies (especially to NSAIDs), asthma, viral eye infections, or issues with bleeding and clotting before starting Zyflur 0.03% Eye Drop 5 ml.

If Zyflur 0.03% Eye Drop 5 ml are prescribed for a condition linked to long-term pain, continue using them as directed by your doctor. For short-term pain, they can be stopped once your pain is relieved. Following your doctor’s advice.

Zyflur 0.03% Eye Drop 5 ml are generally safe when used in the dose and duration advised by a doctor. Do not use more than the recommended dose

Zyflur 0.03% Eye Drop 5 ml may cause side effects such as stinging or burning sensation of the eyes, and an increase or decrease in the size of the pupil, redness of the eye, and temporary blurred vision. If these side effects persist or worsen, consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Plot No.160 Hsiidc, Ind. Area, Sector-3, Karnal - 132001, Haryana (India)
Other Info - ZYF0038

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