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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Zycel MD 200 Tablet is used to reduce pain and swelling in muscles and joints. It treats painful conditions of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness in the backbone), cervical spondylitis (wear and tear of spinal discs in the neck), and menstrual pain. It contains Celecoxib, which works by blocking the cyclo-oxygenase (COX) enzyme that causes pain and inflammation in the body. Thereby, it helps relieve pain and swelling. It may cause side effects such as indigestion, stomach pain, diarrhoea, oedema, and flatulence.

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Composition :

CELECOXIB-200MG

Manufacturer/Marketer :

Zydus Cadila

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zycel MD 200 Tablet

Zycel MD 200 Tablet is used to reduce pain and swelling in muscles and joints. It treats painful conditions of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness in the backbone), cervical spondylitis (wear and tear of spinal discs in the neck), and menstrual pain. Arthritis is a condition that causes swelling and pain in one or more joints, worsening over time.

Zycel MD 200 Tablet contains Celecoxib, which works by blocking the cyclo-oxygenase (COX) enzyme that causes pain and inflammation in the body. It thereby helps relieve pain and swelling associated with various types of arthritis, spondylitis, low back pain, and menstrual pain.

Your doctor will advise you on how often you take this medicine based on your medical condition. In some cases, you may experience indigestion, stomach pain, diarrhoea, oedema, and flatulence. Most of the side effects of Zycel MD 200 Tablet do not require medical attention and resolve gradually over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Zycel MD 200 Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Zycel MD 200 Tablet . Do not consume alcohol with Zycel MD 200 Tablet as it may increase the risk of stomach bleeding. Zycel MD 200 Tablet may cause an increased risk of severe heart problems like myocardial infarction and stroke, which can be fatal.

Zycel MD 200 Tablet should not be used by a patient who has undergone recent heart bypass surgery or will undergo it. Zycel MD 200 Tablet increases the risk of severe gastrointestinal conditions like bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal.

Uses of Zycel MD 200 Tablet

Zycel MD 200 Tablet is used for joint pain relief and menstrual cramps. The detailed uses of Zycel MD 200 Tablet are as follows:

  • Relieve pain and inflammation in arthritis: Zycel MD 200 Tablet is primarily used to treat osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It works by blocking the action of COX-2 enzymes, which are responsible for inflammation and pain in joints and muscles.
  • Manage acute pain and menstrual discomfort: Zycel MD 200 Tablet is effective in reducing short-term pain such as post-surgical discomfort or menstrual cramps. Its anti-inflammatory action helps ease swelling and tenderness, providing targeted relief without the sedative effects of opioids.

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Directions for Use

  • Zycel MD 200 Tablet can be taken with or without food, but taking it with food helps reduce stomach upset.
  • It is advised to take Zycel MD 200 Tablet once or twice daily, or as directed by your doctor, at the same time each day for best results.
  • Swallow Zycel MD 200 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Zycel MD 200 Tablet provides effective relief from pain and inflammation associated with arthritis and other musculoskeletal conditions.
  • Helps manage symptoms of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
  • Reduces stiffness, swelling, and joint discomfort to improve mobility.
  • Offers pain relief in acute conditions such as menstrual cramps and postoperative pain.
  • Helps improve quality of life by enabling better physical activity and comfort.
  • Provides long-lasting pain control with convenient dosing.

How Zycel MD 200 Tablet Works

Zycel MD 200 Tablet contains Celecoxib, which works by blocking the cyclo-oxygenase (COX) enzyme that causes pain and inflammation in the body. It thereby helps relieve pain and swelling associated with various types of arthritis, spondylitis, low back pain, and menstrual pain.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Zycel MD 200 Tablet

Do not take more than the prescribed dose of Zycel MD 200 Tablet as it may cause an overdose. The symptoms of overdose include stomach pain, nausea, vomiting, lack of energy, drowsiness, bloody or black tarry stools, vomiting material that is bloody or looks like coffee grounds, loss of consciousness and difficulty breathing or swallowing. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Zycel MD 200 Tablet if you are allergic to any of its ingredients.
  • Zycel MD 200 Tablet may cause an increased risk of severe heart problems like myocardial infarction and stroke, which can be fatal.
  • It should not be used by a patient who has undergone recent heart bypass surgery or will undergo it.
  • Zycel MD 200 Tablet increases the risk of severe gastrointestinal conditions like bleeding, ulceration and perforation of the stomach or intestines, which can be fatal.
  • Elderly patients are at greater risk of gastrointestinal bleeding, so the doctor can limit their dose.
  • Zycel MD 200 Tablet is not recommended for pregnant women, especially in the third trimester, as it may cause harm to the unborn baby (fetus). Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Zycel MD 200 Tablet .
  • Do not consume alcohol with Zycel MD 200 Tablet as it may increase the risk of stomach bleeding or ulcer.
  • If you experience weight loss, diarrhoea, pain or vomiting, please stop taking Zycel MD 200 Tablet and consult a doctor immediately. These might be signs of worsening, Crohn’s disease, or ulcerative colitis (swelling in the digestive tract).

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Zycel MD 200 Tablet:
Taking Ketorolac with Zycel MD 200 Tablet can increase the risk of side effects such as gastrointestinal bleeding and ulcers.

How to manage the interaction:
Taking Zycel MD 200 Tablet with Ketorolac is not recommended, but can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zycel MD 200 Tablet:
Taking Ketorolac with Zycel MD 200 Tablet can increase the risk of gastrointestinal bleeding and ulcers,

How to manage the interaction:
Taking Ketorolac tromethamine with Zycel MD 200 Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
CelecoxibEliglustat
Critical
How does the drug interact with Zycel MD 200 Tablet:
Taking eliglustat with Zycel MD 200 Tablet can significantly increase the blood levels of eliglustat. This may increase the risk of serious side effects.

How to manage the interaction:
Taking Zycel MD 200 Tablet with Eliglustat is not recommended, but can be taken together if prescribed by a doctor. However, consult the doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate and weak pulse. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zycel MD 200 Tablet:
Taking thioridazine and Zycel MD 200 Tablet may increases the blood levels of thioridazine which may cause irregular heart rhythm.

How to manage the interaction:
Taking Zycel MD 200 Tablet with Thioridazine is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Zycel MD 200 Tablet:
Co-administration of Cidofovir with Zycel MD 200 Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Zycel MD 200 Tablet with Cidofovir is not recommended, please consult your doctor before taking it. However, consult the doctor if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zycel MD 200 Tablet:
Co-administration of Zycel MD 200 Tablet with Meloxicam can increase the risk or severity of bleeding and ulcers of the stomach lining leading to serious blood loss.

How to manage the interaction:
Taking Meloxicam with Zycel MD 200 Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a dcovct
CelecoxibPralatrexate
Severe
How does the drug interact with Zycel MD 200 Tablet:
Taking pralatrexate with Zycel MD 200 Tablet can cause high blood levels of Pralatrexate.

How to manage the interaction:
Taking Pralatrexate with Zycel MD 200 Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience any unusual symptoms. Do not discontinue any medications without first consulting your doctor.
CelecoxibIoversol
Severe
How does the drug interact with Zycel MD 200 Tablet:
Taking Zycel MD 200 Tablet with ioversol may increase the risk of kidney problems.

How to manage the interaction:
Although there is a interaction between Zycel MD 200 Tablet and Ioversol, but it can be taken together if prescribed by your doctor. However, consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of hunger, increased or decreased urination, fluid retention, swelling of hands and legs, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zycel MD 200 Tablet:
Coadministration of Zycel MD 200 Tablet with Tenofovir Disoproxil may increase the risk of kidney problems.

How to manage the interaction:
Taking Zycel MD 200 Tablet with Tenofovir Disoproxil together can possibly result in an interaction, but it can be taken if your doctor has advised it. Consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, shortness of breath, muscle cramps, or dizziness. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zycel MD 200 Tablet:
Taking Zycel MD 200 Tablet and Lithium may significantly increase the blood levels of lithium.

How to manage the interaction:
There may be a possibility of interaction between Zycel MD 200 Tablet and Lithium, but it can be taken if prescribed by a doctor. However, contact your doctor if you experience drowsiness, dizziness, confusion, loose stools, vomiting, muscle weakness, muscle incoordination, shaking, blurred vision, ringing in the ear, excessive thirst, or increased urination. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulfate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce tissue inflammation.
  • Do not engage in strenuous exercise, as it may worsen joint pain in arthritis. Instead, you can do stretching, low-impact aerobic exercise like walking on a treadmill, bike riding and swimming. You can also strengthen your muscles by lifting light weights.
  • For chronic conditions such as arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fish are enriched with omega-3 fatty acids that help reduce levels of a chemical called cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammatory conditions. Try to sit as little as possible, and only for a short time (10-15 min). Use a back support, such as a rolled-up towel, at the back of your curve to minimise pain. Keep your knees and hips at a right angle. Additionally, you can use a footrest if needed.

Habit Forming

No

Therapeutic Class

ANALGESICS

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Alcohol

Unsafe

Taking alcohol, along with Zycel MD 200 Tablet , can increase the chances of gastrointestinal bleeding and kidney damage.

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Pregnancy

Unsafe

Zycel MD 200 Tablet is a category C pregnancy drug. It should not be given during pregnancy, especially during the last trimester, as it is known to cause fetal deformities.

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Breast Feeding

Unsafe

Zycel MD 200 Tablet is not recommended for breastfeeding women.

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Driving

Caution

Zycel MD 200 Tablet is not known to cause drowsiness, but if you feel sleepy, please do not operate or drive any machinery.

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Liver

Consult your doctor

If you have had a history of any liver-related diseases, please consult a doctor before taking medicine.

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Kidney

Consult your doctor

If you have had a history of any kidney-related diseases, please consult a doctor before taking medicine.

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Children

Caution

Zycel MD 200 Tablet is not recommended for children under 2 years old. For children aged 2 years or older, take it at the dose and duration prescribed by your doctor.

FAQs

Zycel MD 200 Tablet is used to reduce pain and swelling in muscles and joints. It treats pain in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness of the spine), cervical spondylosis (wear and tear of spinal discs in the neck), and menstrual pain.

Zycel MD 200 Tablet contains Celecoxib, which works by blocking the action of the pain-inducing chemical messenger cyclo-oxygenase (COX) enzyme in the body, which is involved in producing certain chemical substances, such as prostaglandins, that cause pain and swelling. It thereby helps relieve pain and swelling associated with different types of arthritis.

Yes, Zycel MD 200 Tablet can be used to treat menstrual cramps. Zycel MD 200 Tablet is a painkiller that decreases pain and inflammation-inducing chemical messenger known as prostaglandin (PG) production in the body involved in making the uterus (womb) contract during periods.

Arthritis is a chronic condition of the joints characterised by pain and inflammation. Zycel MD 200 Tablet does not cure arthritis, but it relieves symptoms of arthritis, such as joint pain, swelling, and stiffness.

Yes, Zycel MD 200 Tablet may increase the risk of heart problems such as heart attack and stroke, especially when used in high doses or for a prolonged duration. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking Zycel MD 200 Tablet . However, it is recommended to take Zycel MD 200 Tablet at the prescribed dose and for the prescribed duration. It should not be used by the patient who has had recent heart bypass surgery (coronary artery bypass graft - CABG).

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - ZYC0018

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