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compositionComposition:CELECOXIB-200MG
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Zycel 200 Capsule is used to reduce pain and swelling in muscles and joints. It treats painful conditions of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness in the backbone), cervical spondylitis (wear and tear of spinal discs in the neck), and menstrual pain. It contains Celecoxib, which works by blocking the cyclo-oxygenase (COX) enzyme that causes pain and inflammation in the body. Thereby, it helps relieve pain and swelling. It may cause side effects such as indigestion, stomach pain, diarrhoea, oedema, and flatulence.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CELECOXIB-200MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Zycel 200 Capsule

Zycel 200 Capsule is an oral prescription medication used to relieve pain, swelling, and joint stiffness caused by various types of arthritis. It is also commonly prescribed to manage sudden, sharp pain in adults and to treat painful menstrual periods. Zycel 200 Capsule belongs to a class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs).

To get the best results, you should take Zycel 200 Capsule consistently and exactly as your doctor has prescribed. You can take it with or without food, though taking it with a meal can help if it causes an upset stomach. Combining this treatment with lifestyle adjustments, such as physical therapy and gentle joint exercises, can further improve your physical function.

While taking Zycel 200 Capsule , you may experience mild side effects like a mild stomach ache, gas, or dizziness. However, you must seek medical help immediately if you notice serious signs like severe chest pain, shortness of breath, or sudden swelling in your legs. Always consult your doctor if you experience any persistent or concerning symptoms.

Before starting this treatment, talk to your doctor if you have a history of high blood pressure, heart disease, asthma, or stomach ulcers. Do not take this if you have recently had bypass heart surgery, or if you have ever had an allergic reaction or asthma attack after taking aspirin.

Zycel 200 Capsule can interact with blood thinners and certain blood pressure drugs, which can increase the risk of stomach bleeding or kidney issues. If you are pregnant, breastfeeding, or over the age of 65, consult your healthcare provider to discuss whether this medication is appropriate for your specific needs.

Uses of Zycel 200 Capsule

Zycel 200 Capsule is used for joint pain relief and menstrual cramps. The detailed uses of Zycel 200 Capsule are as follows:

  • Osteoarthritis: Zycel 200 Capsule reduces joint pain, swelling, and stiffness, helping you move more comfortably during daily activities.
  • Rheumatoid arthritis: It targets ongoing joint inflammation and pain caused by this autoimmune condition, helping to improve overall joint function.
  • Ankylosing spondylitis: It relieves chronic back pain and spinal stiffness associated with this long-term inflammatory arthritis.
  • Acute pain: It provides short-term relief for sudden pain, such as pain resulting from injuries, dental procedures, or surgical recovery.
  • Primary dysmenorrhea: It helps ease severe menstrual cramps and pelvic pain during your monthly cycle.

Key Benefits

Zycel 200 Capsule helps relieve pain and inflammation, allowing you to move more comfortably and stay active in your daily life. By reducing joint discomfort and stiffness, it supports better mobility and overall physical function. Benefits may include:

  • Helps relieve pain associated with arthritis and other inflammatory conditions.
  • Reduces swelling, inflammation, and joint stiffness.
  • Improves mobility and makes daily activities more comfortable.
  • Supports better sleep by reducing pain-related discomfort.
  • Helps improve participation in physical therapy, exercise, and rehabilitation activities.
  • Promotes long-term joint comfort and overall quality of life.
Side effects of Zycel 200 Capsule
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
Managing Medication-Related Skin Allergies: A Step-by-Step Guide
  • If you experience signs of skin allergies such as redness, itching, or irritation after taking medication, contact your doctor right away.
  • To alleviate skin allergy symptoms, your doctor may change your medication regimen or offer tailored medication management advice.
  • Your doctor may recommend or prescribe drugs to relieve discomfort.
  • Cool compresses or calamine lotion can help relieve redness and itching on the afflicted skin area.
  • Staying hydrated by consuming plenty of water can help relieve discomfort.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

  • Zycel 200 Capsule can be taken with or without food, but taking it with food helps reduce stomach upset.
  • It is advised to take Zycel 200 Capsule once or twice daily, or as directed by your doctor, at the same time each day for best results.
  • Swallow Zycel 200 Capsule as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Zycel 200 Capsule Works

Zycel 200 Capsule contains Celecoxib, which works by blocking the cyclo-oxygenase (COX) enzyme that causes pain and inflammation in the body. It thereby helps relieve pain and swelling associated with various types of arthritis, spondylitis, low back pain, and menstrual pain.
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Alcohol

Unsafe

Taking alcohol, along with Zycel 200 Capsule , can increase the chances of gastrointestinal bleeding and kidney damage.

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Pregnancy

Unsafe

Zycel 200 Capsule is a category C pregnancy drug. It should not be given during pregnancy, especially during the last trimester, as it is known to cause fetal deformities.

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Breast Feeding

Unsafe

Zycel 200 Capsule is not recommended for breastfeeding women.

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Driving

Caution

Zycel 200 Capsule is not known to cause drowsiness, but if you feel sleepy, please do not operate or drive any machinery.

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Liver

Consult your doctor

If you have had a history of any liver-related diseases, please consult a doctor before taking medicine.

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Kidney

Consult your doctor

If you have had a history of any kidney-related diseases, please consult a doctor before taking medicine.

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Children

Caution

Zycel 200 Capsule is not recommended for children under 2 years old. For children aged 2 years or older, take it at the dose and duration prescribed by your doctor.

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Heart

Caution

Zycel 200 Capsule should be taken with caution in patients with heart problems. Please inform your doctor about any existing heart problems before using Zycel 200 Capsule .

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Geriatrics

Caution

Zycel 200 Capsule should be given with caution in elderly patients due to age-related health issues. Seek medical advice before using Zycel 200 Capsule .

What if I have taken an overdose of Zycel 200 Capsule

Zycel 200 Capsule contains Celecoxib. It helps relieve pain, swelling, and inflammation by reducing the production of substances in the body that cause these symptoms. It is commonly used to improve comfort and mobility in conditions affecting the joints, muscles, and bones.

Diet & Lifestyle Advise

  • Engage in low-impact exercise: Activities like swimming, cycling, or walking help keep your joints flexible and strengthen the muscles supporting them without causing extra joint stress.
  • Maintain a healthy weight: Carrying excess weight puts additional pressure on weight-bearing joints like your knees and hips. Losing even a small amount of weight can significantly reduce joint pain.
  • Eat anti-inflammatory foods: Incorporate foods rich in omega-3 fatty acids (like fish and walnuts), berries, leafy greens, and olive oil to help support your joint health naturally.
  • Stay hydrated: Drinking plenty of water is essential for keeping your joint cartilage lubricated and supporting healthy kidney function while taking this medication.
  • Apply warm or cold compresses: Use heating pads to ease stiffness in the morning and ice packs to reduce swelling after physical activity.
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Have a query?

How Soon It Starts Working

  • The time required for Zycel 200 Capsule to start to work: The time required for Zycel 200 Capsule to show its action is clinically unknown.
  • The time for which the effects of Zycel 200 Capsule last: The duration of action for Zycel 200 Capsule is clinically unknown.

What if you forget to take Zycel 200 Capsule

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Monitor your blood pressure: Zycel 200 Capsule can sometimes raise your blood pressure, so it is important to check it regularly while on this treatment.
  • Watch for heart risks: Like other NSAIDs, Zycel 200 Capsule may increase the risk of serious cardiovascular events, such as heart attacks or strokes, especially with long-term use.
  • Limit or avoid alcohol: Drinking alcohol while taking this medication significantly increases your risk of developing stomach ulcers or severe stomach bleeding.
  • Do not combine with other NSAIDs: Avoid taking other pain relievers like ibuprofen, naproxen, or aspirin unless specifically instructed by your doctor, as this can increase your risk of severe side effects.
  • Protect your skin: This medication can make your skin more sensitive to sunlight. Wear sunscreen and protective clothing when outdoors to avoid sunburns.
  • Stop before surgery: Tell your surgeon or dentist that you are taking this medication, as you may need to stop taking it temporarily before certain medical procedures.

Drug-Drug Interactions

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Drug-Drug Interactions

  • Blood thinners (e.g., Warfarin): Taking these together can severely increase the risk of serious stomach bleeding.
  • Blood pressure medicines (like ACE inhibitors or diuretics): This medication may decrease the effectiveness of these drugs and increase the risk of kidney damage.
  • Medicine used in bilpos disoreder Lithium: Zycel 200 Capsule can raise the levels of lithium in your blood to dangerous levels, requiring close monitoring.
  • Other NSAIDs: Combining this with other anti-inflammatory drugs increases the risk of stomach ulcers and bleeding.

Drug-Food Interactions

No interactions found

Drug-Disease Interactions

  • Heart disease or high blood pressure: Zycel 200 Capsule can cause fluid retention and worsen heart failure or elevate blood pressure.
  • Stomach ulcers or bleeding history: Taking this medication increases the risk of recurrent stomach irritation, ulcers, or bleeding.
  • Kidney or liver damage: People with moderate to severe kidney or liver issues may need dose adjustments or may need to avoid Zycel 200 Capsule entirely to prevent worsening organ damage.
  • Asthma (aspirin-sensitive): Do not take this if you experience asthma attacks or severe allergic reactions triggered by aspirin or other NSAIDs.

Drug-Drug Interactions

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How does the drug interact with Zycel 200 Capsule:
Taking thioridazine and Zycel 200 Capsule may increases the blood levels of thioridazine which may cause irregular heart rhythm.

How to manage the interaction:
Taking Zycel 200 Capsule with Thioridazine is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Zycel 200 Capsule:
Taking Ketorolac with Zycel 200 Capsule can increase the risk of gastrointestinal bleeding and ulcers,

How to manage the interaction:
Taking Ketorolac tromethamine with Zycel 200 Capsule is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Zycel 200 Capsule:
Co-administration of Zycel 200 Capsule with Meloxicam can increase the risk or severity of bleeding and ulcers of the stomach lining leading to serious blood loss.

How to manage the interaction:
Taking Meloxicam with Zycel 200 Capsule is not recommended, but can be taken together if prescribed by a doctor. However, consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a dcovct
How does the drug interact with Zycel 200 Capsule:
Co-administration of Cidofovir with Zycel 200 Capsule can increase the risk of kidney problems.

How to manage the interaction:
Taking Zycel 200 Capsule with Cidofovir is not recommended, please consult your doctor before taking it. However, consult the doctor if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to a doctor.
CelecoxibEliglustat
Critical
How does the drug interact with Zycel 200 Capsule:
Taking eliglustat with Zycel 200 Capsule can significantly increase the blood levels of eliglustat. This may increase the risk of serious side effects.

How to manage the interaction:
Taking Zycel 200 Capsule with Eliglustat is not recommended, but can be taken together if prescribed by a doctor. However, consult the doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate and weak pulse. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zycel 200 Capsule:
Taking Ketorolac with Zycel 200 Capsule can increase the risk of side effects such as gastrointestinal bleeding and ulcers.

How to manage the interaction:
Taking Zycel 200 Capsule with Ketorolac is not recommended, but can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zycel 200 Capsule:
Coadministration of Indomethacin with Zycel 200 Capsule can increase the risk of gastrointestinal bleeding and ulcers.

How to manage the interaction:
Although there is a interaction between Indometacin and Zycel 200 Capsule, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Zycel 200 Capsule:
Taking leflunomide with Zycel 200 Capsule affects the liver and may increase the risk of liver problems.

How to manage the interaction:
Although taking Zycel 200 Capsule and leflunomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, abdominal pain, dark-coloured urine, light-coloured stools, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
CelecoxibSulindac
Severe
How does the drug interact with Zycel 200 Capsule:
Taking Zycel 200 Capsule and Sulindac may increase risk of serious gastrointes bleeding and ulcers.

How to manage the interaction:
Although there is a interaction between Sulindac and Zycel 200 Capsule, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Zycel 200 Capsule:
Taking Zycel 200 Capsule with Tenofovir alafenamide may increase risk of kidney problems.

How to manage the interaction:
Although taking Zycel 200 Capsule and Tenofovir alafenamide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

Zycel 200 Capsule is used to reduce pain and swelling in muscles and joints. It treats pain in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness of the spine), cervical spondylosis (wear and tear of spinal discs in the neck), and menstrual pain.
Zycel 200 Capsule contains Celecoxib, which works by blocking the action of the pain-inducing chemical messenger cyclo-oxygenase (COX) enzyme in the body, which is involved in producing certain chemical substances, such as prostaglandins, that cause pain and swelling. It thereby helps relieve pain and swelling associated with different types of arthritis.
Yes, Zycel 200 Capsule can be used to treat menstrual cramps. Zycel 200 Capsule is a painkiller that decreases pain and inflammation-inducing chemical messenger known as prostaglandin (PG) production in the body involved in making the uterus (womb) contract during periods.
Arthritis is a chronic condition of the joints characterised by pain and inflammation. Zycel 200 Capsule does not cure arthritis, but it relieves symptoms of arthritis, such as joint pain, swelling, and stiffness.
Yes, Zycel 200 Capsule may increase the risk of heart problems such as heart attack and stroke, especially when used in high doses or for a prolonged duration. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking Zycel 200 Capsule . However, it is recommended to take Zycel 200 Capsule at the prescribed dose and for the prescribed duration. It should not be used by the patient who has had recent heart bypass surgery (coronary artery bypass graft - CABG).
No, you are not recommended to take Zycel 200 Capsule with warfarin as co-administration of these two medicines may increase bleeding risk more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so the dose can be adjusted appropriately to ensure safe use.
You should avoid using Zycel 200 Capsule if you have gastrointestinal ulcer/bleeding, have undergone planned heart bypass surgery or are pregnant for more than 30 weeks.
Zycel 200 Capsule may reduce the blood pressure-lowering effects of certain blood pressure drugs; you are advised to contact your doctor so the dose can be adjusted appropriately to ensure safe use.
Yes, you can take Zycel 200 Capsule with or without food. However, if you find that it causes an upset stomach, taking it with a meal, a snack, or a glass of milk can help prevent this irritation. Talk to your doctor if stomach pain persists.
Drowsiness is not a common side effect of Zycel 200 Capsule . However, some people may experience mild dizziness or headaches. If you feel dizzy or lightheaded, avoid driving or operating machinery and talk to your doctor.
You should avoid taking Zycel 200 Capsule during pregnancy, especially during the last 3 months (third trimester), as it can cause harm to the unborn baby or cause complications during delivery. If you are pregnant or planning to become pregnant, talk to your doctor to discuss safer alternatives.
It is highly recommended to avoid or limit alcohol consumption while taking Zycel 200 Capsule . Combining alcohol with this medication significantly increases the risk of severe stomach bleeding and irritation. Talk to your doctor if you have concerns about alcohol use.
Mild stomach upset can sometimes be managed by taking the medicine with food. However, if you experience severe, persistent stomach pain, or if you notice dark, tarry stools, stop taking the medication immediately and contact your healthcare provider. Talk to your doctor right away to rule out serious stomach issues.

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Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - ZYC0001
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