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compositionComposition:VIGABATRIN-500MG
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Viby Powder For Oral Solution is used to treat refractory complex partial seizures in adults and children two years of age and older and infantile spasms in children. It contains Vigabatrin. Vigabatrin is an anticonvulsant. It increases the amount of the chemical called gamma-aminobutyric acid (GABA) in the brain. Low levels of GABA cause some seizures. When Vigabatrin increases GABA, it reduces the likelihood of a seizure.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

VIGABATRIN-500MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Viby Powder For Oral Solution

Viby Powder For Oral Solution is used alone or with other medicines to treat refractory complex partial seizures in adults and children two years of age and older and infantile spasms in children. Seizures are considered refractory when two or more AEDs (anti-epileptic drugs) have failed to control the seizures.

Viby Powder For Oral Solution contains Vigabatrin. It increases the amount of the chemical called gamma-aminobutyric acid (GABA) in the brain. Low levels of GABA cause some seizures. When Vigabatrin increases GABA, it reduces the likelihood of a seizure.

In some cases, Viby Powder For Oral Solution may cause side effects such as blue-yellow colour blindness, blurred vision, decreased vision or other vision changes, eye pain, increased seizures and loss of memory or problems with memory. Most of these side effects do not require medical attention and will resolve gradually. However, talk to your doctor if you experience these side effects persistently.

Before taking the Viby Powder For Oral Solution, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Inform your doctor if you are pregnant or planning to become pregnant. You should not breastfeed unless the doctor advises. To treat your condition effectually, continue taking Viby Powder For Oral Solution for as long as your doctor has prescribed.

Uses of Viby Powder For Oral Solution

Viby Powder For Oral Solution is used in the treatment of refractory complex partial seizures and infantile spasms. The detailed uses of Viby Powder For Oral Solution are as follows:

  • Refractory complex partial seizures (CPS): Viby Powder For Oral Solution is indicated as adjunctive therapy for adults and paediatric patients 2 years and older with refractory CPS who have not responded to multiple treatments, and the benefits outweigh the risk of vision loss.
  • Infantile spasms (IS): Viby Powder For Oral Solution is indicated as monotherapy for paediatric patients 1 month to 2 years old with infantile spasms, where benefits outweigh the risk of vision loss.

Key Benefits

  • Viby Powder For Oral Solution contains Vigabatrin. Vigabatrin is an anticonvulsant. 
  • It increases the amount of the chemical called gamma-aminobutyric acid (GABA) in the brain. Low levels of GABA cause some seizures.
  • When Vigabatrin increases GABA, it reduces the likelihood of a seizure.
  • Vigabatrin is used alone or together with other medicines to treat refractory complex partial seizures in adults and children two years of age and older and infantile spasms in children.
  • It is used in patients who have already been treated with other medicines that did not work well.
Side effects of Viby Powder For Oral Solution
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Participating in activities you enjoy, or exercising may also help manage agitation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.

Directions for Use

  • Viby Powder For Oral Solution can be taken with or without food as advised by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Check the label for instructions. Mix the contents of the sachet/package in 10ml of water, then administer the prescribed amount.
  • Do not store the mixture for later use.

How Viby Powder For Oral Solution Works

Viby Powder For Oral Solution contains vigabatrin, which works by directly increasing the levels of a natural calming chemical in the brain called gamma-aminobutyric acid, or GABA. In a healthy brain, GABA acts as a natural brake system, slowing down and stabilising rapid or chaotic electrical signals between nerve cells. Under normal circumstances, an enzyme in the brain called GABA transaminase breaks down this calming chemical. This medicine works by permanently blocking this specific enzyme. By stopping the enzyme from doing its job, the medicine allows GABA levels to build up and remain high in the brain. The resulting increase in GABA helps calm hyperactive nerve pathways. This action prevents the sudden, uncontrolled bursts of electrical activity that trigger infantile spasms or complex partial seizures, helping to restore a more balanced state of brain activity.
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Alcohol

Unsafe

It is unsafe to consume alcohol while taking Viby Powder For Oral Solution since it may worsen the side effects.

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Pregnancy

Caution

There are no adequate and well-controlled studies on pregnant women. Inform your doctor before receiving the Viby Powder For Oral Solution if you are pregnant or planning to become pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

There has been no significant research on using Viby Powder For Oral Solution in breastfeeding/nursing moms. So, let your doctor know if you are a nursing mother before taking Viby Powder For Oral Solution; your doctor will decide whether breastfeeding mothers can take Viby Powder For Oral Solution.

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Driving

Unsafe

Viby Powder For Oral Solution may cause colour blindness or blurred vision; therefore, do not drive or operate machinery.

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Liver

Caution

If you have liver problems, inform your doctor before taking Viby Powder For Oral Solution. Your doctor will weigh the benefits and potential risks before prescribing Viby Powder For Oral Solution.

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Kidney

Caution

If you have kidney problems, inform your doctor before taking Viby Powder For Oral Solution. Your doctor will weigh the benefits and potential risks before prescribing Viby Powder For Oral Solution.

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Children

Consult your doctor

Please consult your doctor. Your doctor will weigh the benefits and risks before prescribing this medicine for your child.

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Heart

Caution

If you have heart problems, inform your doctor before taking Viby Powder For Oral Solution. Your doctor will weigh the benefits and potential risks before prescribing Viby Powder For Oral Solution.

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Geriatrics

Consult your doctor

Limited information available about the use of Viby Powder For Oral Solution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Viby Powder For Oral Solution

If you or your child takes more than the prescribed amount of this medicine, seek immediate emergency medical care. Symptoms of an overdose may include severe sleepiness, dizziness, loss of consciousness, or slowed breathing.

Diet & Lifestyle Advise

  • Prioritise Eye Exams: Since this medicine can cause permanent vision loss, attend all scheduled vision and eye tracking tests. These are typically required before starting, every few months during treatment, and after stopping the medicine.
  • Maintain a Consistent Sleep Schedule: Lack of sleep is a well-documented trigger for seizures. Establish a calming, regular bedtime routine to ensure adequate rest.
  • Keep a Detailed Seizure Diary: Track the time, duration, and details of every seizure, along with daily doses. This helps your healthcare team evaluate how well the treatment is working.
  • Stay Safely Hydrated: Ensure you or your child drinks plenty of fluids, especially when taking the oral solution, to assist general bodily functions and ease digestion.

 

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How Soon It Starts Working

  • The time required for Viby Powder For Oral Solution to start to work: Viby Powder For Oral Solution ideally shows its action within 1 to 2 hours after administration.
  • The time for which the effects of Viby Powder For Oral Solution last: The effect of Viby Powder For Oral Solution lasts for 5 to 7 hours.

What if you forget to take Viby Powder For Oral Solution

Take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and return to your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are highly unsure of what to do, talk to your doctor or pharmacist for guidance.

Storage

• Store in a cool and dry place away from sunlight.• Keep Viby Powder For Oral Solution out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Always check the powder packets before mixing; do not use the medicine if the packaging is torn, wet, or if the powder looks discoloured or clumped.
  • Never stop taking this medicine suddenly. Doing so can cause severe, continuous, and life-threatening seizures. Any reduction in dose must be done slowly under a doctor's supervision.
  • This medicine carries a boxed warning for permanent peripheral vision loss. Make sure to complete all scheduled eye exams, even if you do not notice any changes in your sight.
  • Avoid driving, riding a bike, or operating machinery until you are certain how this medicine affects your coordination and alertness.
  • Always use the precise oral dosing syringe or measuring device provided with the medicine to prepare and take your dose; regular household spoons are not accurate.

Drug-Drug Interactions

verifiedApollotooltip
  • Other Anti-Seizure Medicines: Taking this medicine alongside other seizure drugs (such as clonazepam) can increase drowsiness, cause coordination problems, or alter the levels of these medicines in your blood.
  • Retinal-Damaging Medications: Avoid taking this medicine with other drugs known to cause vision problems or damage the retina, as this can increase the risk of permanent visual field loss.
     
VigabatrinMethylprednisolone
Critical
VigabatrinTamoxifen
Severe

Drug-Drug Interactions

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VigabatrinMethylprednisolone
Critical
How does the drug interact with Viby Powder For Oral Solution:
Co-administration of Methylprednisolone and Viby Powder For Oral Solution together can increase the risk or severity of side effects associated with vision loss.

How to manage the interaction:
Taking Methylprednisolone with Viby Powder For Oral Solution is not recommended, it can be taken if prescribed by the doctor. Regular eye check ups are advised during this treatment. Do not discontinue any medication without consulting a doctor.
VigabatrinTamoxifen
Severe
How does the drug interact with Viby Powder For Oral Solution:
Taking Tamoxifen with Viby Powder For Oral Solution may increase the risk of side effects associated with vision loss.

How to manage the interaction:
Although taking tamoxifen and Viby Powder For Oral Solution together can possibly result in an interaction, it can be taken if a doctor has prescribed it. In case you experience any unusual symptoms, consult a doctor. Routine eye testing is advised during this treatment. Do not stop using any medications without consulting a doctor.
VigabatrinAmiodarone
Severe
How does the drug interact with Viby Powder For Oral Solution:
Co-administration of Viby Powder For Oral Solution and Amiodarone can increase the risk of vision loss.

How to manage the interaction:
Although there is a possible interaction between Viby Powder For Oral Solution and Amiodarone, you can take these medicines together if prescribed by your doctor. Regular eye testing is required during this treatment. If you're having problems with your eyes like vision loss, it's important to consult a doctor. Do not stop using any medications without talking to a doctor.
VigabatrinBudesonide
Severe
How does the drug interact with Viby Powder For Oral Solution:
Taking Budesonide with Viby Powder For Oral Solution, especially for a prolonged period of time, may raise the chance of significant adverse effects (loss of vision).

How to manage the interaction:
Co-administration of Budesonide along with Viby Powder For Oral Solution can lead to an interaction, it can be taken if recommended by a doctor. Regular eye check ups are advised. Do not discontinue any medications without consulting a doctor.
VigabatrinBuprenorphine
Severe
How does the drug interact with Viby Powder For Oral Solution:
When Buprenorphine is used with Viby Powder For Oral Solution, it may increase the risk of side effects such as respiratory difficulties.

How to manage the interaction:
Co-administration of Buprenorphine alongside Viby Powder For Oral Solution can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery. Do not discontinue any medications without consulting a doctor.
VigabatrinKetamine
Severe
How does the drug interact with Viby Powder For Oral Solution:
When Viby Powder For Oral Solution is taken along with Ketamine, it increases the risk or severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Viby Powder For Oral Solution and ketamine, but it can be taken if prescribed by a doctor. However, if you experience dizziness, drowsiness, confusion, difficulty concentrating, and breathing difficulty, impairment in thinking, judgment, and motor coordination, consult the doctor. Do not discontinue the medications without consulting a doctor.
VigabatrinQuinine
Severe
How does the drug interact with Viby Powder For Oral Solution:
Co-administration of Viby Powder For Oral Solution with Quinine may increase the risk of serious side effects associated with vision loss, especially if used together for prolonged periods.

How to manage the interaction:
There may be a possibility of interaction between Viby Powder For Oral Solution and Quinine, but it can be taken if prescribed by a doctor. Routine vision testing is advised during treatment with Viby Powder For Oral Solution. Do not discontinue any medications without a doctor's advice.
VigabatrinTrimethadione
Severe
How does the drug interact with Viby Powder For Oral Solution:
Co-administration of Viby Powder For Oral Solution with Trimethadione may increase the risk of serious side effects associated with vision loss, especially if used together for prolonged periods.

How to manage the interaction:
Although there is a possible interaction between Trimethadione and Viby Powder For Oral Solution, you can take these medicines together if prescribed by a doctor. Routine vision testing is advised during treatment with Viby Powder For Oral Solution. Do not discontinue any medications without a doctor's advice.
VigabatrinPrednisone
Severe
How does the drug interact with Viby Powder For Oral Solution:
Co-administration of Viby Powder For Oral Solution with Prednisone may increase the risk of serious side effects associated with vision loss, especially if used together for prolonged periods.

How to manage the interaction:
There may be a possibility of interaction between Viby Powder For Oral Solution and Prednisone, but it can be taken if prescribed by a doctor. Routine vision testing is advised during treatment with Viby Powder For Oral Solution. Do not discontinue any medications without a doctor's advice.
VigabatrinBetamethasone
Severe
How does the drug interact with Viby Powder For Oral Solution:
Co-administration of Viby Powder For Oral Solution with Betamethasone may increase the risk of serious side effects associated with vision loss, especially if used together for prolonged periods.

How to manage the interaction:
Although there is an interaction, betamethasone can be taken with Viby Powder For Oral Solution if prescribed by the doctor. Routine vision testing is advised during treatment with Viby Powder For Oral Solution. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip

There are no significant established interactions between this medicine and specific foods. It can be safely taken with or without meals.
 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

Not enough scientific literature available around this hence it is best to consult your physician

Therapeutic Class

[ANTICONVULSANT]

FAQs

Viby Powder For Oral Solution is used alone or with other medicines to treat refractory complex partial seizures in adults and children two years of age and older and infantile spasms in children.
Viby Powder For Oral Solution contains Vigabatrin. It increases the amount of the chemical called gamma-aminobutyric acid (GABA) in the brain. Low levels of GABA cause some seizures. When Vigabatrin increases GABA, it reduces the likelihood of a seizure.
No, Viby Powder For Oral Solution should not be stopped even if you start feeling better. Abrupt stopping may cause continuous seizures, which can be difficult to control. To treat your condition effectually, continue taking Viby Powder For Oral Solution for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Viby Powder For Oral Solution; your doctor will gradually reduce the dose to avoid precipitating seizures.
Brain cells must work (fire) at a specific rate to function normally. During a seizure, brain cells are forced to perform faster than usual. During a seizure, Vigabatrin causes chemical changes in the brain that slow down the firing of brain cells.
The most concerning adverse effect is the possibility of losing peripheral vision. This means that people may be unable to see clearly to the sides, as well as high up and low down. The risk of new and severe vision loss remains as long as Viby Powder For Oral Solution is used and possibly after the medicine is stopped. Periodic vision testing (suggested every three months) is essential for Viby Powder For Oral Solution patients but cannot reliably prevent visual impairment.
Viby Powder For Oral Solution may cause suicidal thoughts such as killing or harming yourself. People taking Viby Powder For Oral Solution should be closely monitored for suicidal thoughts or behaviour. Speak with your doctor immediately if you need to.
Pay close attention to any changes in mood, behaviour, thoughts, or feelings, especially if they are sudden.
No, your doctor will adjust the dose of Vigabatrin tablets according to your child’s age and body weight. This will have the same effect as the powder.
Viby Powder For Oral Solution may cause common psychiatric side effects such as nervousness, agitation, irritability, aggression, depression, sleeplessness, thought disturbance and paranoia (feeling suspicious without reason). These are temporary side effects and are usually reversible when the dose is lowered or gradually discontinued. Severe psychological disturbances (such as feeling extremely happy or over-excited which may cause strange behaviour and the person may feel detached from reality) are rare but may also occur.
If someone takes more than the recommended dose of Viby Powder For Oral Solution, it may lead to overdose resulting in symptoms such as drowsiness or loss/depressed level of consciousness. Therefore, if you take more than the recommended dose of Viby Powder For Oral Solution, please consult your doctor immediately or go to a nearby hospital.
Yes, Viby Powder For Oral Solution may affect memory or concentration in some people. Other factors may also contribute to memory problems like anxiety, depression, sleep disturbance and frequent seizures (fits). Consult your doctor if you experience any of these effects.
If you forget to take a dose of Viby Powder For Oral Solution, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the risk of side effects.
It is essential to take Viby Powder For Oral Solution at prescribed intervals. Make a plan and ask your doctor to assist you in adjusting to time zone changes. Keep Viby Powder For Oral Solution in its original packaging and carry doctor’s prescription. It is possible to find Viby Powder For Oral Solution abroad depending on your destination. However, it is best to make sure you have enough stock for yourself.
Yes, this medicine can cause a permanent loss of side (peripheral) vision. Because of this risk, your doctor will require regular vision exams before and during treatment. Talk to your doctor immediately if you notice any changes in your sight.
Dissolve the prescribed powder completely in the specific amount of water recommended by your doctor. Stir well and drink the entire mixture immediately. Talk to your doctor or pharmacist if you need help with preparation.
This medicine may cause harm to an unborn baby. However, uncontrolled seizures also carry serious risks. If you are pregnant or planning to become pregnant, talk to your doctor to carefully weigh the benefits and risks.
Yes, you can take this medicine with or without food. Try to be consistent in how you take it each day to help keep stable drug levels in your body. Talk to your doctor or pharmacist if you have questions.
Do not give another dose right away without professional advice. Contact your doctor or pharmacist immediately to find out the safest next step for your child.
Generally, vision tests are required before starting, every three months during treatment, and for about six months after stopping the medicine. Talk to your doctor about your specific testing schedule.
Yes, drowsiness, sleepiness, and fatigue are common side effects of this medicine. Avoid driving or operating machinery until you know how this medicine affects your alertness. Talk to your doctor if this sleepiness interferes with daily activities.

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Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - VIB0090

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