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compositionComposition:UPADACITINIB-30MG
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Upadashine 30 mg Tablet 10's is used to treat ulcerative colitis, Crohn's disease, arthritis, atopic dermatitis (eczema), and a few other inflammatory conditions when other therapies are ineffective. Upadacitinib, a component of this medication, helps lessen inflammation, discomfort, oedema, stiffness, and itching.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

UPADACITINIB-30MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Return Policy :

Not Returnable

About Upadashine 30 mg Tablet 10's

Upadashine 30 mg Tablet 10's is an oral prescription medication used to treat chronic inflammatory conditions, such as moderate to severe rheumatoid arthritis, psoriatic arthritis, and severe eczema. It helps manage these conditions by targeting specific pathways in the body that cause painful swelling and tissue damage. By controlling this overactive immune response, Upadashine 30 mg Tablet 10's helps reduce symptoms and prevent further joint or skin damage.

To get the best results, you should take Upadashine 30 mg Tablet 10's consistently once every day, ideally at the same time. You can take this tablet with or without food, but you must swallow it whole without crushing or chewing. Along with taking your medicine, gentle physical therapy, a balanced diet, and protecting your skin can help improve your overall treatment outcomes.

While taking Upadashine 30 mg Tablet 10's, some people may experience mild side effects like cold symptoms, nausea, or acne. However, because Upadashine 30 mg Tablet 10's affects your immune system, you must contact your healthcare provider immediately if you develop signs of a serious infection, high fever, or unexpected shortness of breath.

Do not start Upadashine 30 mg Tablet 10's if you have a serious active infection unless your doctor has specifically determined that treatment is appropriate. Before starting treatment, tell your doctor if you have or have previously had tuberculosis, shingles, hepatitis B or C, recurrent infections, blood clots, heart or blood vessel disease, cancer, or liver problems. Your doctor may perform tests and assess your individual risks before treatment.

Upadashine 30 mg Tablet 10's can interact with other drugs that suppress the immune system, certain live vaccines, and grapefruit juice, which can raise medicine levels in your body. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, consult your doctor before starting treatment.

Uses of Upadashine 30 mg Tablet 10's

Upadashine 30 mg Tablet 10's is used in the treatment of certain inflammatory and autoimmune conditions. The detailed uses of Upadashine 30 mg Tablet 10's are as follows:

  • Rheumatoid Arthritis: Reduces joint pain, stiffness, and swelling by calming the overactive immune system.
  • Psoriatic Arthritis: Helps clear skin plaques and relieves joint pain and spinal inflammation.
  • Atopic Dermatitis (Eczema): Relieves severe, constant itching and helps clear up red, inflamed skin lesions.
  • Ulcerative Colitis and Crohn's Disease: Targets chronic inflammation in the digestive tract to help achieve and maintain remission.
  • Ankylosing Spondylitis: Reduces back pain and spinal stiffness, helping you move more comfortably.

Key Benefits

Upadashine 30 mg Tablet 10's helps reduce inflammation and control symptoms of several long-term inflammatory conditions. The benefits depend on the condition being treated, and improvement may be noticed within weeks, although the response can vary from person to person.

Benefits may include:

  • Helps reduce joint pain, swelling, and stiffness in inflammatory joint conditions.
  • May improve movement, physical function, and the ability to perform daily activities.
  • Helps reduce itching and improve skin symptoms in atopic dermatitis.
  • May help control inflammation and support remission in certain inflammatory bowel diseases.
  • Can help improve overall comfort and quality of life by controlling troublesome symptoms.
  • Supports long-term management of inflammatory conditions when used regularly with appropriate medical monitoring.

Directions for Use

  • Upadashine 30 mg Tablet 10's can be taken with or without food.
  • It is recommended to take the medicine as directed by your doctor, depending on your medical condition.
  • Swallow Upadashine 30 mg Tablet 10's as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Upadashine 30 mg Tablet 10's Works

Upadashine 30 mg Tablet 10's is a Janus kinase (JAK) inhibitor that works by blocking specific signals inside immune cells that contribute to inflammation. By reducing these overactive signals, it helps control the immune response and decrease inflammation. This can help reduce symptoms such as joint pain and swelling, skin inflammation, and intestinal inflammation in conditions for which Upadashine 30 mg Tablet 10's is prescribed. It modifies immune activity but does not completely switch off the immune system.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Upadashine 30 mg Tablet 10's, so please consult a doctor.

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Pregnancy

Unsafe

Upadashine 30 mg Tablet 10's must not be taken during pregnancy. If you are a woman of child-bearing potential, use effective contraception during the treatment with Upadashine 30 mg Tablet 10's.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Upadashine 30 mg Tablet 10's. Please consult a doctor if you have any concerns.

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Driving

Safe if prescribed

Upadashine 30 mg Tablet 10's generally does not affect your ability to drive. However, drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this. Upadashine 30 mg Tablet 10's is not recommended for patients with severe liver problems.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Upadashine 30 mg Tablet 10's is not safe for use in children below 12 years of age. Caution should be exercised for children above 12 years. However, your paediatrician will prescribe the medicine only if needed.

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Heart

Caution

Careful consideration and monitoring of the patient is required due to increased risks of heart-related problems, particularly in patients with existing cardiovascular risk factors.

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Geriatrics

Caution

No serious adverse effects were observed; however, it requires careful consideration and caution due to the increased risk of certain adverse events, particularly infections.

What if I have taken an overdose of Upadashine 30 mg Tablet 10's

If you suspect an accidental overdose or have taken more than your prescribed dose, seek emergency medical care immediately or call your local poison control center. Do not wait for symptoms to appear before seeking help.

Diet & Lifestyle Advise

  • Focus on anti-inflammatory foods: Incorporate foods rich in omega-3 fatty acids, such as salmon, walnuts, and flaxseeds, alongside plenty of colorful vegetables and berries to help manage general inflammation.
  • Protect your skin barrier: If you are taking this for eczema, take short, lukewarm showers rather than hot baths, and apply a thick, fragrance-free moisturizer immediately afterward to lock in moisture.
  • Choose gentle, low-impact exercise: If you have joint inflammation, activities like swimming, walking, or cycling can keep your joints flexible and strengthen supporting muscles without causing excess strain.
  • Support your gut health: If you have an inflammatory bowel condition, keep a food journal to identify specific trigger foods, and focus on eating smaller, more frequent meals.
  • Practice proper infection prevention: Because Upadashine 30 mg Tablet 10's lowers your body's ability to fight germs, wash your hands frequently with soap and water, and avoid close contact with people who are sick.
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Have a query?

How Soon It Starts Working

The time required for Upadashine 30 mg Tablet 10's to start to work: The time required for Upadashine 30 mg Tablet 10's to show its action is unknown.

The time for which the effects of Upadashine 30 mg Tablet 10's last: The duration of action for Upadashine 30 mg Tablet 10's is clinically unknown.

What if you forget to take Upadashine 30 mg Tablet 10's

If you miss a dose of Upadashine 30 mg Tablet 10's, take it as soon as you remember. However, if your next scheduled dose is less than 12 hours away, skip the missed dose and return to your normal schedule. Do not take two doses at the same time to make up for a missed one.

Storage

•Store Upadashine 30 mg Tablet 10's tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Get screened for tuberculosis (TB): Your doctor must test you for TB before you start taking Upadashine 30 mg Tablet 10's and monitor you closely during treatment.
  • Avoid live vaccines: Do not receive any live vaccines (such as the shingles vaccine or nasal spray flu vaccine) while taking Upadashine 30 mg Tablet 10's, as it can increase your risk of getting the infection.
  • Watch for signs of blood clots: Be alert for sudden chest pain, coughing up blood, or swelling and redness in your leg, and seek emergency help immediately if these occur.
  • Monitor your lab results: Attend all scheduled appointments for blood tests, as your doctor will need to check your liver function, cholesterol levels, and blood counts
  • Report unusual skin changes: Perform regular skin self-checks and tell your doctor if you notice any new growths, unusual moles, or sores that do not heal.
  • Discuss cancer risk with your doctor: Upadashine 30 mg Tablet 10's may increase the risk of certain cancers, including lymphoma and some types of skin cancer. Tell your doctor if you currently have or have previously had cancer.
  • Attend recommended screening: Follow your doctor's advice about routine cancer screening and skin examinations. Report any new or changing skin growth, unusual mole, or sore that does not heal.
  • Seek urgent medical help: Get immediate medical attention if you develop sudden chest pain, breathing difficulty, weakness on one side of the body, or painful swelling in a leg.

verifiedApollotooltip
  • Antifungal medicines (e.g., ketoconazole, itraconazole): These medicines can increase Upadashine 30 mg Tablet 10's levels in the body and raise the risk of side effects.
  • Antibiotics (e.g., clarithromycin): Some antibiotics may increase Upadashine 30 mg Tablet 10's levels and increase the risk of side effects.
  • Anti-seizure medicines (e.g., carbamazepine, phenytoin): These medicines may reduce Upadashine 30 mg Tablet 10's levels and make the treatment less effective.
  • Tuberculosis medicines (e.g., rifampicin): Some tuberculosis medicines may reduce Upadashine 30 mg Tablet 10's levels and decrease its effectiveness.
  • Other immune-suppressing medicines (e.g., ciclosporin, azathioprine): Combining Upadashine 30 mg Tablet 10's with other medicines that suppress the immune system may increase the risk of serious infections and other side effects.
  • Biological medicines (e.g., adalimumab, etanercept): Using Upadashine 30 mg Tablet 10's with other biological medicines that affect the immune system is generally not recommended because it may increase the risk of serious infections.

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verifiedApollotooltip
  • Grapefruit and grapefruit juice: Avoid grapefruit products while taking Upadashine 30 mg Tablet 10's, as they may increase the level of Upadashine 30 mg Tablet 10's in your body and raise the risk of side effects.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Upadashine 30 mg Tablet 10's is used to treat ulcerative colitis, Crohn's disease, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, atopic dermatitis (eczema), and a few other inflammatory conditions.
Upadashine 30 mg Tablet 10's contains Upadacitinib, which works by reducing overactive immune system activity in the body.
Diarrhoea might be a side-effect of Upadashine 30 mg Tablet 10's. Eat non-spicy meals and drink plenty of fluids to prevent dehydration if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Upadashine 30 mg Tablet 10's is not recommended for patients with severe liver impairment. Dose adjustment may be needed in patients with mild to moderate liver impairment. Please consult the doctor if you have liver problems.
Prior to starting treatment with Upadashine 30 mg Tablet 10's, your doctor may suggest a few blood tests, such as an active or latent tuberculosis test, CBC (complete blood count), LFT (liver function test), and lipid profile tests, should be done.
Caution should be exercised if you have liver problems, tuberculosis, gastrointestinal perforations, vaccinations, cancer, or serious infections. Inform your physician of your medical history before starting treatment.
Some people may begin to notice improvements in their symptoms, such as reduced joint pain or clearer skin, within a few weeks of starting treatment. However, it can take several months to experience the full benefits. Consult your doctor if you do not notice any changes.
Because Upadashine 30 mg Tablet 10's can lower your body's ability to fight infections, you should contact your doctor right away if you experience any cold, flu, or infection symptoms. Your doctor may advise you to temporarily pause your treatment.
Significant weight gain is not a common side effect of Upadashine 30 mg Tablet 10's. However, if you experience sudden weight gain, swelling in your hands or feet, or shortness of breath, this could point to other medical issues.
No, you should not stop taking your medication even if you feel completely better. Stopping treatment suddenly can cause your symptoms or inflammation to return. Always consult your doctor before making any changes to your medication routine.

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Country of origin

India

Manufacturer/Marketer address

Sun House, Cts No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - UPA0052
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