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  3. Trexjoy 1%W/W Topical Gel 20 gm

Trexjoy 1%W/W Topical Gel 20 gm, Pack of 1 GEL
Trexjoy 1%W/W Topical Gel 20 gm, Pack of 1 GEL
Trexjoy 1%W/W Topical Gel 20 gm, Pack of 1 GEL
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Trexjoy 1%W/W Topical Gel belongs to the class of antimetabolite medications used in the treatment of psoriasis. This medicine contains methotrexate which works by interfering with the immune system process that causes psoriasis. Common side effects include nausea, vomiting, fatigue, mouth sores, and loss of appetite.
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Composition :

METHOTREXATE-1%W/W

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Expires on or after :

About Trexjoy 1%W/W Topical Gel

Trexjoy 1%W/W Topical Gel belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat severe psoriasis. Psoriasis is a skin disorder in which skin cells multiply faster than usual. This causes scaling, redness, and thickness of the skin. Psoriatic patches generally occur on the knees, elbows, scalp, and lower back.

Trexjoy 1%W/W Topical Gel contains 'Methotrexate', which works by suppressing the overactive immune system that is responsible for causing psoriasis.

In some cases, Trexjoy 1%W/W Topical Gel may cause common side-effects such as nausea, vomiting, fatigue, mouth sores, and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you have a weak immune system, low blood cell count, liver or kidney problems. Do not use Trexjoy 1%W/W Topical Gel if you are pregnant or breastfeeding. Avoid consuming alcohol whilst on treatment with Trexjoy 1%W/W Topical Gel. Inform your doctor about your medications and health condition to rule out any unpleasant side effects/interactions.

Uses of Trexjoy 1%W/W Topical Gel

Treatment of Psoriasis

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Apply Trexjoy 1%W/W Topical Gel as a thin layer on the clean and dry affected area.• Wash your hands before and after using Trexjoy 1%W/W Topical Gel to prevent the spread of infection.

Medicinal Benefits

Trexjoy 1%W/W Topical Gel belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat severe psoriasis. It works by suppressing the overactive immune system that is responsible for causing psoriasis. Trexjoy 1%W/W Topical Gel may also be used to treat eczema/dermatitis, rheumatoid arthritis, and psoriatic arthritis.

How Trexjoy 1%W/W Topical Gel Works

Trexjoy 1%W/W Topical Gel contains 'Methotrexate', which works by suppressing the overactive immune system that is responsible for causing psoriasis.

Storage

• Store in a cool and dry place away from sunlight.• Keep Trexjoy 1%W/W Topical Gel out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Trexjoy 1%W/W Topical Gel 20 gm
  • Rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of Trexjoy 1%W/W Topical Gel

Use Trexjoy 1%W/W Topical Gel in prescribed dosage only. An overdose of Trexjoy 1%W/W Topical Gel may cause symptoms like a burning sensation of the skin, pruritus, urticaria, ecchymosis and reversible alopecia, sloughing over pressure points, acute ulcerations of psoriatic plaques, severe mucositis, and reactivation of phototoxic responses. Seek emergency medical help if you face any of these symptoms.

Drug Warnings

Do not use Trexjoy 1%W/W Topical Gel if you are allergic to any of the contents. Avoid using Trexjoy 1%W/W Topical Gel if you are pregnant or breastfeeding. Inform your doctor if you have immunodeficiency conditions, bone marrow problems, low white blood cell count, low platelet count, serious anaemia, liver or kidney problems, ulceration in the stomach or bowels, poor general condition, received any vaccinations or if are due to have any, diabetes, ascites (fluid in the stomach area), lung problems or fluid in the lungs. 

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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METHOTREXATE-1%W/WCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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METHOTREXATE-1%W/WCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Caffeine may reduce the effectiveness of Trexjoy 1%W/W Topical Gel 20 gm. Avoid taking caffeine while taking Trexjoy 1%W/W Topical Gel 20 gm. This can increase the risk or severity of side effects.

Diet & Lifestyle Advise

  • Include foods such as cherries, berries, leafy vegetables, salmon, sardines, and fish rich in omega-3 fatty acids.
  • Consume antioxidant-rich spices and herbs like cumin, ginger, sage and thyme.
  • Avoid processed foods, refined sugars, and fatty foods.
  • Limit intake of food that might trigger allergies, such as dairy products, soy, eggs, and nuts.
  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
  • Reducing stress and maintaining a good sleep cycle would be helpful.
  • Avoiding getting in contact with harsh soaps, detergents and rough fabrics.

Habit Forming

No

Therapeutic Class

ANTIMETABOLITES

Trexjoy 1%W/W Topical Gel Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while on treatment with Trexjoy 1%W/W Topical Gel.

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Pregnancy

Unsafe

Trexjoy 1%W/W Topical Gel may cause serious birth defects. It is not recommended to use Trexjoy 1%W/W Topical Gel while you are pregnant.

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Breast Feeding

Unsafe

Trexjoy 1%W/W Topical Gel passes into breast milk. Avoid breastfeeding whilst on treatment with Trexjoy 1%W/W Topical Gel.

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Driving

Caution

It is not known if Trexjoy 1%W/W Topical Gel affects your ability to drive. Drive only if you are alert after using Trexjoy 1%W/W Topical Gel.

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Liver

Caution

Limited information is available. Please consult your doctor if you have liver impairment before using Trexjoy 1%W/W Topical Gel.

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Kidney

Caution

Limited information is available. Please consult your doctor if you have kidney impairment before using Trexjoy 1%W/W Topical Gel.

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Children

Caution

Limited information is available. Please consult your doctor if you have any concerns regarding the usage of Trexjoy 1%W/W Topical Gel in children.

Have a query?

FAQs

Trexjoy 1%W/W Topical Gel belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat severe psoriasis. Psoriasis is a skin disorder in which skin cells multiply faster than usual.

Trexjoy 1%W/W Topical Gel works by suppressing the overactive immune system that is responsible for causing psoriasis. Trexjoy 1%W/W Topical Gel interferes with the growth of cells that multiply faster than usual, thereby helping in treating psoriasis.

Do not cover the treated skin with dressings after applying Trexjoy 1%W/W Topical Gel unless told by the doctor. Covering the skin can increase the amount of medicine absorbed through the skin leading to harmful effects.

Continue using Trexjoy 1%W/W Topical Gel for as long as your doctor has prescribed it. Do not be reluctant to speak with your doctor if you experience any difficulty while using Trexjoy 1%W/W Topical Gel.

Protect your skin from sunlight as it will help prevent sunburns and psoriasis flares. Avoid using tanning beds or sunlamps.

Do not apply Trexjoy 1%W/W Topical Gel on wounds, cuts, or damaged skin unless advised by the doctor.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - TRE0227

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 18, 2025 | 7:01 AM IST

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Reference

  1. https://www.aad.org/public/diseases/psoriasis/treatment/medications/methotrexate
  2. https://dermnetnz.org/topics/methotrexate

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