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compositionComposition:TOBRAMYCIN-300MG
prescription
Prescription Medicine
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Tobamist Respules 5X5 ml is an aminoglycoside antibiotic used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis. It helps by inhibiting the protein synthesis of the bacterial cell and therby helps fight infection in the lungs. Sometimes, you may experience certain common side effects, such as discolouration of the substance you cough up (sputum), worsening of lung function test results, runny or stuffy nose, sneezing, hoarseness,feeling unwell, muscle pain, etc

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

TOBRAMYCIN-300MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Inhalation

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Tobamist Respules 5X5 ml

Tobamist Respules 5X5 ml is a prescription inhalation medicine used to manage and treat chronic lung infections in patients with cystic fibrosis. It specifically targets a type of bacteria that commonly infects the airways of individuals with this condition. By clearing these bacteria, the medicine helps maintain and improve lung function so patients can breathe more comfortably.

For the medicine to work effectively, you must take it with strict consistency as directed by your doctor, usually in alternating treatment cycles. To support your lung health and get the best results, combine this treatment with daily airway clearance techniques and stay well-hydrated to help loosen thick mucus. Because this is an inhaled medication, there are no specific food requirements, so you can take it regardless of your meal times.

While taking Tobamist Respules 5X5 ml, some people may experience mild side effects like a temporary change in their voice, throat soreness, or a mild cough. However, you must contact your doctor immediately if you experience serious symptoms such as ringing in your ears, hearing changes, severe dizziness, or difficulty breathing right after inhalation.

Before starting Tobamist Respules 5X5 ml, talk to your doctor if you have a history of kidney problems, hearing impairment, or muscle weakness disorders. Do not take this if you have had a severe allergic reaction to similar inhaled antibiotics in the past.

This medicine can interact with other drugs that cause kidney damage or hearing loss, so your doctor should know all the medications you are taking. You should also consult your healthcare provider if you are pregnant, breastfeeding, or an older adult, as special monitoring may be required.

Uses of Tobamist Respules 5X5 ml

Tobamist Respules 5X5 ml is used to manage and treat chronic lung infections in patients with cystic fibrosis. The detailed uses of Tobamist Respules 5X5 ml are as follows:

  • Cystic Fibrosis Lung Infections: Tobamist Respules 5X5 ml helps clear and control the growth of bacteria in the lungs, reducing the severity of ongoing infections.
  • Worsening Lung Function: By keeping bacterial growth in check, this medicine helps prevent the decline in lung health and supports easier breathing.

Key Benefits

Tobamist Respules 5X5 ml helps manage chronic airway infections, improving respiratory health and supporting better lung function. With regular use as prescribed, it helps reduce respiratory flare-ups, preserve lung capacity, and improve overall quality of life.

  • Supports Easier Breathing: By helping control airway infections, this medicine reduces respiratory symptoms and makes breathing more comfortable.
  • Helps Prevent Severe Lung Flare-Ups: Regular use helps reduce the frequency and severity of respiratory infections, lowering the need for hospitalisation and intravenous antibiotic treatment.
  • Promotes Better Lung Function: By preserving lung capacity and reducing chronic respiratory symptoms, this medicine helps you stay active and perform daily activities with greater ease and comfort.
Side effects of Tobamist Respules 5X5 ml
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Avoid smoking and intake of any tobacco products as it worsens lung disorders.
  • Get a physical examination, follow your doctor's instructions, and get required vaccinations.
  • Be physically active and eat healthy food.
  • Prefer practising yoga and meditation to reduce stress and anxiety.
  • Practice good hygiene and stay away from places where air pollution is high.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Check the label for directions before using it. Twist off the top of the respule (a small plastic container containing a solution) and pour the solution into the nebuliser chamber. This solution is made into a fine mist to breathe in. Inhale the medicine slowly and deeply through the nebuliser’s mouthpiece.
  • Clean the nebulizer pieces (cup, mouthpiece, mask, and tubing) after each use.

How Tobamist Respules 5X5 ml Works

Tobamist Respules 5X5 ml contains tobramycin, which is an antibiotic that goes directly to the source of the infection in your lungs when inhaled. It works by binding to the components inside the bacteria that make vital proteins. By disrupting this protein production, the medicine stops the bacteria from growing and multiplying, eventually causing them to die. Since the treatment is inhaled, it delivers a high concentration of the active medicine directly to your airways while keeping the level of medicine in the rest of your body very low.
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Alcohol

Caution

It is unknown if alcohol affects Tobamist Respules 5X5 ml. However, it is advisable to limit or avoid alcohol as a precautionary measure.

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Pregnancy

Caution

Tobamist Respules 5X5 ml may not be recommended to be used in pregnancy. If you are pregnant, please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor as there is no substantial research yet on using Tobamist Respules 5X5 ml in breastfeeding/nursing mothers.

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Driving

Safe if prescribed

Tobamist Respules 5X5 ml may not affect your ability to drive, use, or operate machines.

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Liver

Caution

Limited information about the usage of Tobamist Respules 5X5 ml in patients with liver disease is available. Please consult your physician. Your doctor will weigh the benefits and potential risks before prescribing Tobamist Respules 5X5 ml.

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Kidney

Caution

Limited information about the usage of Tobamist Respules 5X5 ml in patients with kidney disease is available. Please consult your physician. Your doctor will weigh the benefits and potential risks before prescribing Tobamist Respules 5X5 ml.

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Children

Caution

Children and adolescents aged six and up are eligible to use Tobamist Respules 5X5 ml. Tobamist Respules 5X5 ml should not be given to children under the age of six.

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Heart

Consult your doctor

Please consult your doctor if you have any concerns regarding the usage of Tobamist Respules 5X5 ml in heart patients.

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Geriatrics

Caution

Tobamist Respules 5X5 ml should be used with caution in elderly patients due to an increased risk of side effects. It is important to consult a healthcare professional before use.

What if I have taken an overdose of Tobamist Respules 5X5 ml

If you inhale too much of this medicine or accidentally swallow it, seek emergency medical care immediately.

Diet & Lifestyle Advise

  • Perform your chest physical therapy or airway clearance techniques before using your Tobamist Respules 5X5 ml treatment to ensure the medicine reaches deep into your lungs.
  • Drink plenty of water throughout the day to help thin and loosen the sticky mucus in your airways.
  • Follow a high-calorie, nutritious diet recommended by your healthcare provider to help your body maintain the energy needed to fight off infections.
  • Avoid smoking, secondhand smoke, and other lung irritants like strong chemical fumes or heavy dust.
     
health query

Have a query?

How Soon It Starts Working

The time required for Tobamist Respules 5X5 ml to start to work: The onset time of Tobamist Respules 5X5 ml has not been clinically established. The time for which the effects of Tobamist Respules 5X5 ml last: The duration of Tobamist Respules 5X5 ml’s effect is clinically not established.

What if you forget to take Tobamist Respules 5X5 ml

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is less than 6 hours away, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

.•Store the medicine in the refrigerator between 2°C and 8°C (36°F and 46°F) to keep it stable.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Always check the liquid in the vial before use; it should be clear or pale yellow. If it is cloudy, dark, or contains particles, do not use it.
  • Do not mix Tobamist Respules 5X5 ml with any other medications in your nebuliser cup.
  • Always use the exact nebuliser and compressor model recommended by your healthcare team to ensure you receive the correct dose.
  • If you use multiple inhaled medications, follow the specific sequence advised by your doctor (usually bronchodilators first, then airway clearance, and Tobamist Respules 5X5 ml last).
  • Clean, disinfect, and air-dry your nebuliser parts thoroughly after every use to prevent the growth of harmful bacteria.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Certain water pills (diuretics): Taking strong diuretics alongside Tobamist Respules 5X5 ml may increase the risk of hearing damage or kidney problems.
  • Other antibiotics: Combining this medicine with other injectable antibiotics that can affect the kidneys or hearing may increase the risk of side effects.
TobramycinCidofovir
Critical
TobramycinTenofovir disoproxil
Severe

Drug-Drug Interactions

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TobramycinCidofovir
Critical
How does the drug interact with Tobamist Respules 5X5 ml:
Coadministration of cidofovir with Tobamist Respules 5X5 ml can cause kidney problems.

How to manage the interaction:
Taking Tobamist Respules 5X5 ml with Cidofovir is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without consulting a doctor.
TobramycinTenofovir disoproxil
Severe
How does the drug interact with Tobamist Respules 5X5 ml:
Coadministration of Tobamist Respules 5X5 ml with Tenofovir disoproxil can increase the risk of kidney problems.

How to manage the interaction:
Taking Tenofovir disoproxil with Tobamist Respules 5X5 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
TobramycinBumetanide
Severe
How does the drug interact with Tobamist Respules 5X5 ml:
When Tobamist Respules 5X5 ml is taken with Bumetanide, the amount of Tobamist Respules 5X5 ml in the blood can go up.

How to manage the interaction:
Although there is a possible interaction between Tobamist Respules 5X5 ml and Bumetanide, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
TobramycinFurosemide
Severe
How does the drug interact with Tobamist Respules 5X5 ml:
Taking Furosemide with Tobamist Respules 5X5 ml can increase the risk of hearing loss and kidney problems.

How to manage the interaction:
Although there is a possible interaction between Tobamist Respules 5X5 ml and Furosemide, you can take these medicines together if prescribed by your doctor. Do not discontinue any medications without consulting your doctor.
TobramycinPancuronium
Severe
How does the drug interact with Tobamist Respules 5X5 ml:
Using pancuronium with Tobamist Respules 5X5 ml can increase the risk of respiratory depression(hypoventilation).

How to manage the interaction:
Although taking Pancuronium and Tobamist Respules 5X5 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without first talking to your doctor.
TobramycinTorasemide
Severe
How does the drug interact with Tobamist Respules 5X5 ml:
Co-administration of Tobamist Respules 5X5 ml with torasemide increases the risk of toxicity.

How to manage the interaction:
Although taking Tobamist Respules 5X5 ml and torasemide together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as blurred vision, dry mouth, dry skin, frequent urination, nausea, and stomach pain, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
TobramycinTubocurarine
Severe
How does the drug interact with Tobamist Respules 5X5 ml:
Using Tobamist Respules 5X5 ml with tubocurarine can increase the risk of respiratory depression(hypoventilation).

How to manage the interaction:
There may be a possibility of interaction between Tobamist Respules 5X5 ml and Tubocurarine, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
TobramycinDoxacurium chloride
Severe
How does the drug interact with Tobamist Respules 5X5 ml:
Taking Tobamist Respules 5X5 ml with doxacurium chloride can increase the risk of respiratory depression(hypoventilation).

How to manage the interaction:
Although there is a possible interaction between Tobamist Respules 5X5 ml and Doxacurium chloride, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
TobramycinTacrolimus
Severe
How does the drug interact with Tobamist Respules 5X5 ml:
Taking tacrolimus with Tobamist Respules 5X5 ml may increase risk of kidney problems.

How to manage the interaction:
Although taking tacrolimus and Tobamist Respules 5X5 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
TobramycinTenofovir alafenamide
Severe
How does the drug interact with Tobamist Respules 5X5 ml:
Taking tenofovir alafenamide with Tobamist Respules 5X5 ml can increase the risk of kidney problems.

How to manage the interaction:
Although taking Tenofovir alafenamide and Tobamist Respules 5X5 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Tobamist Respules 5X5 ml when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Tobamist Respules 5X5 ml belongs to the class of aminoglycoside antibiotics. Tobamist Respules 5X5 ml is used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis patients aged six years and older.
Tobamist Respules 5X5 ml contains Tobramycin, an aminoglycoside antibiotic that fights pulmonary infection by interfering with protein synthesis in Pseudomonas bacterial cells and allows you to breathe easier.
Please do not stop using Tobamist Respules 5X5 ml until the course prescribed by your doctor has been completed. If you stop taking Tobamist Respules 5X5 ml too soon, your symptoms may recur.
Tobamist Respules 5X5 ml is recommended not to use it for more than the prescribed duration. Please reach out to your doctor if your symptoms do not improve or if it becomes worse.
Tobamist Respules 5X5 ml is only used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis patients.
Yes, you should typically continue using your medicine even if you have a cold, as it helps manage your underlying lung infection. However, talk to your doctor if your breathing symptoms worsen significantly.
Hoarseness or changes in your voice are common temporary side effects because the inhaled mist directly contacts your vocal cords. Rinsing your mouth and gargling with water after each use can help prevent this. Talk to your doctor if it persists.
No, you should never mix Tobamist Respules 5X5 ml with any other medications in the nebuliser cup. Each medicine must be taken separately to ensure they work correctly and safely. Talk to your doctor for the correct schedule.
If you need to cough, you can pause your nebuliser, cough, and then resume your treatment. Try to complete the entire dose as prescribed. Talk to your doctor if coughing prevents you from completing your treatment.
This medicine may cause harm to an unborn baby. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor to weigh the benefits and risks.
Yes, the vials can be kept at room temperature for up to 28 days if a refrigerator is not available. Ensure they are kept in their original foil pouch and protected from intense light. Talk to your pharmacist if you are unsure.
Generally, you should use your bronchodilator first to open your airways, followed by chest physical therapy to loosen mucus, and use Tobamist Respules 5X5 ml last to target the bacteria directly. Talk to your doctor to confirm your specific sequence.

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Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - TOB0011
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