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Tenvir-L Tablet is used to treat HIV infection. It contains Lamivudine and Tenofovir disoproxil fumarate which work by interfering with the working of enzymes necessary for the reproduction of the virus. In some cases, this medicine may cause side effects such as dizziness, nausea, vomiting, diarrhoea, weakness, or rash. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

LAMIVUDINE-300MG+TENOFOVIR DISOPROXIL FUMARATE-300MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Tenvir-L Tablet

Tenvir-L Tablet is a prescription medication used to treat and manage HIV-1 infection. It is an oral tablet that belongs to a class of antiviral medicines designed to help keep the virus under control. By reducing the amount of virus in your body, this medicine helps your immune system stay stronger and lowers your risk of developing infections or complications related to the condition.

For this medication to work effectively, you must take it consistently every single day. Missing doses can cause the virus to become resistant to the treatment, making it much harder to manage in the future. You can take this tablet with or without food, but it is best to take it at the same time each day to maintain a steady level of the medicine in your body. Incorporating regular, gentle exercise and eating a balanced diet can also support your overall immune health.

Tenvir-L Tablet is generally well-tolerated, but some people may experience mild side effects like nausea, loose stools, or headaches. However, you must contact your doctor immediately if you experience signs of severe issues, such as deep and rapid breathing, severe stomach pain, unusual tiredness, or yellowing of your skin or eyes, which could indicate a buildup of acid in your blood or liver damage.

Before you begin taking this medicine, tell your doctor if you have any pre-existing health conditions. Do not take this if you have advanced kidney disease unless your doctor has specifically adjusted your treatment. It is also highly important to let your doctor know if you have hepatitis B, as stopping this medicine suddenly can cause a severe flare-up of your liver condition.

Certain medicines, including some pain relievers and other antiviral drugs, can interact with Tenvir-L Tablet and increase the risk of kidney damage. Avoid drinking alcohol regularly while taking this medicine, as it can place extra strain on your liver. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, talk to your doctor or pharmacist to ensure this medicine is used safely.

Uses of Tenvir-L Tablet

Tenvir-L Tablet is used to treat and manage HIV-1 infection. The detailed uses of Tenvir-L Tablet are as follows:

  • HIV-1 Infection: Tenvir-L Tablet is prescribed alongside other antiviral medications to treat HIV-1. It helps control the infection by reducing the viral load, which allows the immune system to recover and work better.
  • Chronic Hepatitis B Management: In patients who have both HIV-1 and chronic hepatitis B, this medicine helps manage and control the hepatitis B virus to protect liver cells from ongoing damage.

Key Benefits

Tenvir-L Tablet helps control viral infection by reducing the amount of virus in the body and supporting your immune system. With regular use, it helps maintain long-term health, simplifies treatment, and improves overall quality of life.

  • Supports Long-Term Viral Control: By keeping the amount of virus in the body at very low levels, this medicine helps strengthen your body's natural defence system and reduces the risk of infections and illness.
  • Convenient Daily Treatment: By combining two antiviral medicines into a single daily oral tablet, this medicine simplifies your treatment routine and makes it easier to stay consistent with therapy.
  • Promotes Better Long-Term Health: Consistent use helps maintain effective viral suppression, supports immune health, and improves long-term treatment outcomes, allowing you to lead a healthier and more active life.
Side effects of Tenvir-L Tablet
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Managing Medication-Triggered Pancreatitis: A Step-by-Step Guide:
  • If you take medication and get severe stomach pain, feel nauseous, vomit, or have a fever, get emergency medical help right away. This could be a sign of pancreatitis, an inflammation of the pancreas.
  • Your doctor may alter your treatment plan, provide supportive therapy, or prescribe alternative medications to manage the reaction. They will also perform regular tests to monitor your progress and adjust your treatment as needed.
  • Follow your doctor's advice, including dietary recommendations and lifestyle changes, and avoid triggers like alcohol and fatty foods.
  • Monitor your condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

Directions for Use

  • Tenvir-L Tablet can be taken with food as prescribed by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Tenvir-L Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Tenvir-L Tablet Works

Tenvir-L Tablet contains two active components that work together to stop the HIV virus from multiplying in your body. Both of these ingredients target a specific protein or enzyme that the virus needs to copy its genetic material and spread. The first active component blocks the virus from building its DNA chains, effectively halting the replication process. The second active component works in a similar, complementary way to further disrupt the viral life cycle. Together, they lower the amount of HIV in your blood to very low or even undetectable levels, protecting your vital immune cells from being destroyed.
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Alcohol

Unsafe

Avoid alcohol consumption with Tenvir-L Tablet as it may increase the risk of liver damage.

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Pregnancy

Caution

Tenvir-L Tablet is given to pregnant women if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Tenvir-L Tablet as it may pass into breast milk. Therefore, please consult a doctor if you are breastfeeding.

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Driving

Caution

Tenvir-L Tablet may cause dizziness in some people. Therefore, avoid driving or operating heavy machinery if you feel dizzy after taking Tenvir-L Tablet .

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Liver

Caution

Take Tenvir-L Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Tenvir-L Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Tenvir-L Tablet is not recommended for children below 18 years of age.

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Heart

Caution

Inform your doctor if you have any existing heart disease. Your doctor will prescribe this medicine only if the potential benefits outweigh the risks.

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Geriatrics

Caution

Tenvir-L Tablet should be given to elderly patients only if prescribed by a doctor. If you have any concerns, please consult your doctor.

What if I have taken an overdose of Tenvir-L Tablet

If you take more than your prescribed dose, seek immediate medical attention, even if you do not feel sick.

Diet & Lifestyle Advise

  • Support Bone Health: Since some components of this medicine can affect bone density, ensure you eat foods rich in calcium and Vitamin D, like leafy greens, dairy, or fortified foods.
  • Protect Your Kidneys: Drink plenty of water throughout the day to keep your kidneys well-hydrated, which helps them process the medication safely.
  • Avoid Alcohol: Limit or completely avoid alcohol consumption to reduce the strain on your liver and prevent potential interactions.
  • Maintain Balanced Nutrition: Eat a variety of nutrient-dense foods to support your immune system's recovery and keep your energy levels steady.
health query

Have a query?

How Soon It Starts Working

The time required for Tenvir-L Tablet to start to work: The time required for Tenvir-L Tablet to show its action is unknown. The time for which the effects of Tenvir-L Tablet last: The duration of action for Tenvir-L Tablet is clinically unknown.

What if you forget to take Tenvir-L Tablet

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is only a few hours away, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

•Store Tenvir-L Tablet at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original bottle or packaging to protect them from moisture and light.

Drug Warnings

  • Never stop taking Tenvir-L Tablet suddenly without consulting your doctor, especially if you have a hepatitis B infection, as this can cause a severe, life-threatening flare-up of your liver condition.
  • Keep all appointments for your scheduled blood tests so your doctor can regularly check your kidney function and liver health.
  • Ensure you refill your prescription several days before your supply runs out so you never miss a dose and risk viral resistance.
  • Tell any healthcare provider you visit, including your dentist, that you are taking Tenvir-L Tablet before you undergo any medical procedures or start new medications.

 

Drug-Drug Interactions

verifiedApollotooltip
  • Kidney-damaging medicines: Avoid taking this medicine with other drugs that can harm your kidneys, such as certain pain relievers (like ibuprofen), or specific antibiotics and antivirals, as this can increase the risk of severe kidney issues.
  • Other antivirals: Do not use this medicine in combination with other medications that contain the same active ingredients to avoid accidental overdose and toxicity.
Tenofovir disoproxil + LamivudineDidanosine
Critical
Tenofovir disoproxil + LamivudineEmtricitabine
Critical

Drug-Drug Interactions

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Tenofovir disoproxil + LamivudineDidanosine
Critical
How does the drug interact with Tenvir-L Tablet:
Coadministration of Didanosine with Tenvir-L Tablet can increase the risk of serious side effects.

How to manage the interaction:
Taking Didanosine with Tenvir-L Tablet is not recommended, it can be taken if your doctor prescribes it. However, if you experience nausea, vomiting, stomach pain, fatigue, decreased hunger, breathing dfficulty, muscle weakness, or numbness, tingling, or pain in the hands and feet, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxil + LamivudineEmtricitabine
Critical
How does the drug interact with Tenvir-L Tablet:
Taking Tenvir-L Tablet with Emtricitabine can decrease the effectiveness of the medications in treating HIV.

How to manage the interaction:
Taking Emtricitabine with Tenvir-L Tablet is not recommended, but it can be taken if your doctor prescribes it. Contact a doctor if your symptoms do not improve. Do not stop taking any medication without consulting a doctor.
Tenofovir disoproxil + LamivudinePhenytoin
Severe
How does the drug interact with Tenvir-L Tablet:
Coadministration of Phenytoin and Tenvir-L Tablet can reduce the levels of Tenofovir disoproxil, which can lead to low treatment outcomes.

How to manage the interaction:
Taking Tenvir-L Tablet and Phenytoin together can result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
Tenofovir disoproxil + LamivudineVoclosporin
Severe
How does the drug interact with Tenvir-L Tablet:
Co-administration of Voclosporin and Tenvir-L Tablet can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Voclosporin and Tenvir-L Tablet together can lead to an interaction, it can be taken when your doctor advises. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Tenofovir disoproxil + LamivudineNeomycin
Severe
How does the drug interact with Tenvir-L Tablet:
Coadministration of Neomycin and Tenvir-L Tablet can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Neomycin and Tenvir-L Tablet together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Tenofovir disoproxil + LamivudineOlsalazine
Severe
How does the drug interact with Tenvir-L Tablet:
Coadministration of Olsalazine and Tenvir-L Tablet can increase the risk of developing kidney problems.

How to manage the interaction:
Taking Olsalazine and Tenvir-L Tablet together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Tenofovir disoproxil + LamivudineValdecoxib
Severe
How does the drug interact with Tenvir-L Tablet:
Taking Valdecoxib and Tenvir-L Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Valdecoxib and Tenvir-L Tablet together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Tenofovir disoproxil + LamivudineFosphenytoin
Severe
How does the drug interact with Tenvir-L Tablet:
When Tenvir-L Tablet is taken with Fosphenytoin, it may decrease the effectiveness in treating in your condition.

How to manage the interaction:
Taking Fosphenytoin with Tenvir-L Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
Tenofovir disoproxil + LamivudineLomitapide
Severe
How does the drug interact with Tenvir-L Tablet:
Taking Tenvir-L Tablet and lomitapide together can increase the risk of liver damage

How to manage the interaction:
There may be a possibility of interaction between Tenvir-L Tablet and Lomitapide, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, swollen or painful joints, unexpected bleeding or bruises, skin rash, itching, vomiting, abdominal pain, light-colored stool, dark-colored urine, yellowing of the skin or eyes, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
Tenofovir disoproxil + LamivudineBexarotene
Severe
How does the drug interact with Tenvir-L Tablet:
Taking bexarotene together with Tenvir-L Tablet increases the risk of pancreatitis (inflammation of the pancreas).

How to manage the interaction:
There may be a possibility of interaction between Tenvir-L Tablet and Bexarotene, but it can be taken if prescribed by a doctor. If you're having symptoms like nausea, vomiting, stomach pain, contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Tenvir-L Tablet when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIRETROVIRAL AGENTS]

FAQs

Tenvir-L Tablet is used to treat HIV infection. It helps decrease the chance of developing AIDS (acquired immunodeficiency syndrome).
Tenvir-L Tablet contains Lamivudine and Tenofovir disoproxil fumarate. Tenvir-L Tablet works by interfering with the functioning of nucleotide and nucleoside reverse transcriptase enzymes which are necessary for the reproduction of the virus. Together, Tenvir-L Tablet helps in treating HIV infection.
Tenvir-L Tablet may cause bone problems such as osteonecrosis (death of bone tissue due to loss of blood supply to the bone), especially in HIV patients taking combination antiretroviral therapy. However, if you experience joint pains, stiffness (especially shoulder, knee or hip) or difficulty in movement, please consult a doctor immediately.
HIV infection may still be transmitted to other persons while using Tenvir-L Tablet . Tenvir-L Tablet reduces the risk of transmission, but still, HIV infection is contagious. Therefore, discuss with a doctor regarding precautions to be taken to avoid transmission of HIV while taking Tenvir-L Tablet .
Tenvir-L Tablet does not cure HIV infection. Tenvir-L Tablet reduces the amount of HIV virus in the body and improves the functioning of the immune system.
Tenvir-L Tablet should be used with caution in patients with existing infections as it may worsen the infection. However, please consult a doctor if you notice any signs of infection or inflammation.
Tenvir-L Tablet may cause lactic acidosis (excess of lactic acid in the blood), a rare but severe side effect, especially in women who are very obese and in people with liver disease. However, if you experience stomach pain, vomiting or nausea while taking Tenvir-L Tablet , please consult a doctor immediately.
Tenvir-L Tablet is safe if used in the dose and duration as prescribed by your doctor. Do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if you experience any of the side effects.
Always take Tenvir-L Tablet exactly as advised by your doctor. Do not crush or break it. You can take Tenvir-L Tablet with food or between meals.
If you forget to take a dose of Tenvir-L Tablet , take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.
The common side effects of Tenvir-L Tablet are dizziness, nausea, vomiting, diarrhoea, weakness and rash. If these side effects persist or worsen, please consult your doctor.
No, you must not stop taking this medicine without discussing it with your doctor. Stopping it can cause the virus to multiply quickly and become resistant to future treatments. Talk to your doctor if you have concerns.
Mild nausea is a common side effect when starting this medicine and often goes away after a few weeks. Taking your dose with a light meal or before bed may help. If the nausea is severe or does not improve, talk to your doctor.
If you are pregnant, planning to become pregnant, or breastfeeding, you must consult your healthcare provider. They will evaluate the benefits and potential risks to ensure the safest treatment plan for you and your baby. Talk to your doctor.
It is highly recommended to limit or avoid alcohol while taking this medicine. Alcohol can increase the risk of liver damage and worsen potential side effects like dizziness. Talk to your doctor or pharmacist.
Some active components of this medicine are cleared through the kidneys and can cause kidney strain over time. Your doctor will perform regular blood and urine tests to monitor your kidney health. Talk to your doctor.
If you have hepatitis B, stopping this medication suddenly can cause a severe, dangerous flare-up of your infection, leading to liver damage. Your doctor will monitor your liver closely if you must stop taking it. Talk to your doctor.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013.
Other Info - TEN0200
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