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compositionComposition:ESOMEPRAZOLE-40MG
prescription
Prescription Medicine
info
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S-Ppi 40 mg Tablets reduces the amount of acid your stomach makes. It treats gastroesophageal reflux disease (GERD), stomach ulcers and Zollinger-Ellison syndrome (overproduction of acid due to pancreatic tumour). It helps in reducing the stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn. In some cases, it may cause common side effects like headache, diarrhoea, nausea, abdominal pain, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Dr. Aneela S , PhD, M Pharmacy
Reviewed By Dr. Syed Akram , MBBS, MD
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More about the Product

Composition :

ESOMEPRAZOLE-40MG

Manufacturer/Marketer :

Blue Cross Laboratories Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About S-Ppi 40 mg Tablets

S-Ppi 40 mg Tablets is a prescription medication used to manage conditions caused by excessive stomach acid. It is commonly prescribed to treat gastroesophageal reflux disease (GERD), heal acid-related damage in the food pipe, and prevent stomach ulcers. By lowering the amount of acid your stomach produces, esomeprazole helps your digestive system heal.

To get the best results, you must take S-Ppi 40 mg Tablets consistently at the same time every day, usually once daily. It is highly recommended to take this medicine on an empty stomach, at least one hour before a meal, as food can interfere with how it is absorbed. Combining this medication with simple lifestyle changes, such as eating smaller portions and avoiding late-night snacks, can significantly improve your recovery.

While taking this medicine, you might experience mild and temporary side effects such as headaches, gas, or mild diarrhoea. However, if you develop severe, watery diarrhoea, persistent stomach pain, or joint discomfort, you should contact your doctor right away.

Before starting this medication, talk to your doctor if you have severe liver damage, low magnesium levels, or osteoporosis. Do not take this medicine if you have had an allergic reaction to similar acid-reducing drugs, or if you are currently taking medications containing nelfinavir.

This medicine can affect how other drugs are absorbed in your stomach, particularly certain blood thinners, antifungals, and iron supplements, while alcohol and smoking can worsen your acid symptoms. If you are pregnant, breastfeeding, or an elderly individual, you should consult your doctor to ensure this medicine is appropriate for your specific needs.

Uses of S-Ppi 40 mg Tablets

S-Ppi 40 mg Tablets is used to manage conditions caused by excessive stomach acid and help protect the digestive tract from acid-related damage. The detailed uses of S-Ppi 40 mg Tablets are as follows: 

  • Gastroesophageal Reflux Disease (GERD): S-Ppi 40 mg Tablets helps by reducing the production of stomach acid, which prevents acid from flowing back into the food pipe and causing painful heartburn.
  • Erosive Esophagitis: S-Ppi 40 mg Tablets helps heal the physical damage and irritation caused by stomach acid in the lining of your food pipe.
  • Stomach and Duodenal Ulcers: S-Ppi 40 mg Tablets helps by lowering acid levels, which allows active ulcers to heal and prevents new ulcers from forming, especially if you are taking daily pain relief medications.
  • Zollinger-Ellison Syndrome: S-Ppi 40 mg Tablets helps manage this rare condition by controlling the extremely high amounts of acid naturally produced by the stomach.
     

Key Benefits

S-Ppi 40 mg Tablets contains esomeprazole, a proton pump inhibitor that helps reduce excess stomach acid, providing long-lasting relief from acid-related symptoms and protecting the digestive tract from further irritation. By controlling acid production throughout the day and night, it supports both symptom relief and healing.

  • Long-Lasting Relief from Heartburn and Acid Reflux: By reducing the amount of acid produced in the stomach, S-Ppi 40 mg Tablets helps relieve the burning sensation of heartburn and discomfort associated with acid reflux, allowing you to eat, sleep, and carry out daily activities more comfortably.
  • Supports Healing of the Food Pipe: Lower stomach acid levels create a favourable environment for irritated or damaged oesophageal tissues to heal, helping reduce inflammation, discomfort, and pain while swallowing.
  • Protection Against Stomach Ulcers: S-Ppi 40 mg Tablets helps protect the stomach lining from acid-related damage and may reduce the risk of ulcers, particularly in people who need long-term treatment with certain pain-relieving medicines.
     
Side effects of S-PPI 40 mg Tablets
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Directions for Use

To ensure S-Ppi 40 mg Tablets works effectively and safely, please follow these instructions:

  • Take this medicine exactly as prescribed by your doctor. Do not change your dose or stop taking it without consulting them first.
  • Take the capsule or tablet on an empty stomach, ideally at least one hour before your morning meal.
  • Swallow the medicine whole with a full glass of water. Do not crush, chew, or split the capsule or tablet, as this can destroy the protective coating designed to make it past your stomach acid safely.
  • If you have trouble swallowing capsules, talk to your doctor or pharmacist about safe alternative ways to take this medication.
     

How S-Ppi 40 mg Tablets Works

S-Ppi 40 mg Tablets contains esomeprazole, which belongs to a group of medicines known as proton pump inhibitors. Inside your stomach lining, there are tiny cellular pumps that produce the acid needed to digest food. When you take this medicine, it temporarily shuts down many of these pumps, directly reducing the total amount of acid your stomach makes. By lowering acid production, the medicine raises the pH levels inside your stomach. This makes the stomach fluids less acidic, meaning that any fluid that does splash back into your food pipe is much milder and will not cause burning or tissue damage. This acid control gives your digestive tract the necessary time to heal from irritation or ulcers.
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Alcohol

Caution

Drinking alcohol with S-Ppi 40 mg Tablets may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid, limit alcohol or contact doctor before intake of S-Ppi 40 mg Tablets .

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Pregnancy

Consult your doctor

S-Ppi 40 mg Tablets is safe for use in pregnant women. However, please consult your physician before taking the medicine. Your doctor will weigh the benefits and potential risks before prescribing it.

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Breast Feeding

Consult your doctor

S-Ppi 40 mg Tablets is safe for use in lactating mothers. However, please consult your physician before taking the medicine. Your doctor will weigh the benefits and potential risks before prescribing it.

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Driving

Caution

In some cases, S-Ppi 40 mg Tablets may cause dizziness, sleepy, or blur vision. If you observe these symptoms do not drive or operate heavy machinery until you feel better.

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Liver

Consult your doctor

S-Ppi 40 mg Tablets should be taken with precaution in patients with liver disease. Please consult your physician.

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Kidney

Consult your doctor

Patients with kidney disease should consult a doctor before taking S-Ppi 40 mg Tablets .

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Children

Caution

S-Ppi 40 mg Tablets should not be prescribed for children under 5 years of age. S-Ppi 40 mg Tablets is generally prescribed from 5-16 years of children for the treatment of acid-related damage of the food pipe (erosive esophagitis).

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Heart

Consult your doctor

S-Ppi 40 mg Tablets should be taken with caution in patients with heart disease. Please consult your physician.

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Geriatrics

Safe

S-Ppi 40 mg Tablets is safe for use in geriatric patients if prescribed by the physician.

What if I have taken an overdose of S-Ppi 40 mg Tablets

Do not take more than the prescribed dose of S-Ppi 40 mg Tablets as it may cause overdose. The symptoms of overdose include blurred vision, confusion, drowsiness, sweating, nausea, fast heartbeat, dry mouth, headache or flushing. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Identify and Avoid Trigger Foods: Limit foods and beverages that may trigger acid reflux, such as spicy foods, citrus fruits, tomatoes, onions, chocolate, caffeine, and high-fat meals, as they can weaken the valve between the stomach and food pipe.
  • Eat Smaller, More Frequent Meals: Consume smaller meals throughout the day instead of large portions to help reduce pressure on the stomach and lower the risk of acid reflux.
  • Avoid Lying Down After Eating: Do not lie down, bend over, or go to bed for at least two to three hours after meals to help keep stomach acid from flowing back into the food pipe.
  • Elevate the Head of Your Bed: Raise the head of your bed by 6 to 9 inches using blocks or a wedge pillow to help prevent acid reflux while sleeping.
  • Wear Loose-Fitting Clothing: Choose loose-fitting clothes around the waist to avoid unnecessary pressure on the abdomen and stomach.
     
health query

Have a query?

How Soon It Starts Working

The time required for S-Ppi 40 mg Tablets to start to work: S-Ppi 40 mg Tablets ideally shows its action within 1 hour after administration. The time for which the effects of S-Ppi 40 mg Tablets last: The effect of S-Ppi 40 mg Tablets lasts for 9 hours.

What if you forget to take S-Ppi 40 mg Tablets

If you miss a dose, take it as soon as you remember. If it is almost time for next dose, skip the missed dose and take next dose at regular time.

Storage

Store S-Ppi 40 mg Tablets at room temperature, keeping it between 20°C and 25°C (68°F to 77°F). Keep the medication in its original container or blister pack to protect it from moisture and light. Do not store this medicine in the bathroom, near the kitchen sink, or in

Drug Warnings

  • Inspect the Medicine Before Use: Check the packaging before use to ensure the seals are intact and the tablets or capsules are not damaged or discoloured.
  • Attend Regular Health Monitoring: If you are taking this medicine for a long period, your doctor may recommend blood tests to monitor your magnesium and vitamin B12 levels.
  • Be Aware of Bone Health Risks: Long-term use of acid-reducing medicines may slightly increase the risk of bone fractures, particularly in the hip, wrist, or spine. Speak with your doctor about whether calcium and vitamin D supplementation is appropriate for you.
  • Avoid Prolonged Use Without Medical Advice: Do not take this medicine for longer than recommended by your doctor, as stopping it suddenly after prolonged use may cause increased stomach acid production.
  • Seek Medical Advice if Symptoms Persist: Contact your doctor if your symptoms do not improve after a few weeks of regular use or if they become worse.
     

Drug-Drug Interactions

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Drug-Drug Interactions

Esomeprazole can affect how some medicines are absorbed or processed in the body, which may alter their effectiveness or increase the risk of side effects. Inform your doctor if you are taking any of the following medicines, as they may interact with S-Ppi 40 mg Tablets :

  • Medicines Requiring Stomach Acid for Absorption: S-Ppi 40 mg Tablets may reduce the absorption and effectiveness of medicines that require stomach acid to work properly, such as ketoconazole, itraconazole, nelfinavir, or atazanavir.
  • Medicines with Increased Blood Levels: S-Ppi 40 mg Tablets may increase the levels and side effects of certain medicines, including diazepam, digoxin, and phenytoin.
  • Methotrexate: Taking S-Ppi 40 mg Tablets with methotrexate may cause methotrexate to accumulate in the body and increase the risk of serious side effects.
  • Warfarin: S-Ppi 40 mg Tablets may alter the blood-thinning effects of warfarin, and your doctor may need to monitor your blood clotting levels more closely.

Drug-Food Interactions

  • Food: Taking S-Ppi 40 mg Tablets with food may delay and reduce its absorption, making it less effective. Take it on an empty stomach, preferably at least one hour before a meal.

Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking S-Ppi 40 mg Tablets , as it may worsen your condition or require additional monitoring:

  • Severe liver damage: Your liver processes this medicine; if your liver is not working well, the drug can build up, and your doctor may need to prescribe a lower dose.
  • Osteoporosis: Long-term use of this medicine can weaken bones, potentially worsening pre-existing osteoporosis or increasing fracture risk.
  • Lupus: This medicine may trigger or worsen symptoms of cutaneous lupus erythematosus, an autoimmune skin condition.
     
EsomeprazoleRilpivirine
Critical
EsomeprazoleCitalopram
Severe

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
How does the drug interact with S-PPI 40 mg Tablets:
S-PPI 40 mg Tablets may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking S-PPI 40 mg Tablets with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.
EsomeprazoleCitalopram
Severe
How does the drug interact with S-PPI 40 mg Tablets:
Combining S-PPI 40 mg Tablets with Citalopram can increase the risk of irregular heart rhythm. .

How to manage the interaction:
Co-administration of S-PPI 40 mg Tablets with Citalopram can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any symptoms like irregular heart rhythm, dizziness, fainting, or shortness of breath, it's important to contact your doctor immediately. Do not stop using any medications without a doctor's advice.
EsomeprazolePazopanib
Severe
How does the drug interact with S-PPI 40 mg Tablets:
S-PPI 40 mg Tablets decreases the absorption of Pazopanib. This results in reduced efficacy of Pazopanib.

How to manage the interaction:
Although taking S-PPI 40 mg Tablets and Pazopanib can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.
EsomeprazoleClopidogrel
Severe
How does the drug interact with S-PPI 40 mg Tablets:
Coadministration of Clopidogrel with S-PPI 40 mg Tablets may reduce the effectiveness of clopidogrel.

How to manage the interaction:
Taking clopidogrel and S-PPI 40 mg Tablets together possibly has an interaction, but you can take these medications together if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleGefitinib
Severe
How does the drug interact with S-PPI 40 mg Tablets:
Taking gefitinib with S-PPI 40 mg Tablets may reduce the effectiveness of gefitinib.

How to manage the interaction:
Although taking S-PPI 40 mg Tablets and Gefitinib together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Gefitionib 12 hours before or after taking S-PPI 40 mg Tablets. Do not stop taking any medications without consulting a doctor.
EsomeprazoleMethotrexate
Severe
How does the drug interact with S-PPI 40 mg Tablets:
Co-administration of methotrexate and S-PPI 40 mg Tablets can increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although taking S-PPI 40 mg Tablets with Methotrexate can result in an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience headache, dizziness, nausea and vomiting. Do not discontinue any medications without consulting a doctor.
EsomeprazoleErlotinib
Severe
How does the drug interact with S-PPI 40 mg Tablets:
Coadministration of erlotinib and S-PPI 40 mg Tablets can reduce effects of erlotinib.

How to manage the interaction:
Taking Erlotinib and S-PPI 40 mg Tablets together is generally avoided as it can possibly result in an interaction. It can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
EsomeprazoleAcalabrutinib
Severe
How does the drug interact with S-PPI 40 mg Tablets:
S-PPI 40 mg Tablets may interfere with the absorption of Acalabrutinib and reduce their efficacy.

How to manage the interaction:
Taking S-PPI 40 mg Tablets with Acalabrutinib together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EsomeprazoleAtazanavir
Severe
How does the drug interact with S-PPI 40 mg Tablets:
S-PPI 40 mg Tablets reduces the absorption of atazanavir, resulting in reduced efficacy of atazanavir.

How to manage the interaction:
Although there is a possible interaction between S-PPI 40 mg Tablets and atazanavir, they can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
EsomeprazoleDacomitinib
Severe
How does the drug interact with S-PPI 40 mg Tablets:
S-PPI 40 mg Tablets can make Dacomitinib less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of S-PPI 40 mg Tablets with Dacomitinib can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTACIDS]

FAQs

S-Ppi 40 mg Tablets is used to treat Hyperacidity, Heartburn, Stomach ulcer, and Zollinger-Ellison syndrome.
S-Ppi 40 mg Tablets is a proton pump inhibitor (PPI), which is a type of medication. Proton pumps are enzymes found in the stomach lining that aid in the production of acid needed for digestion. Esomeprazole impairs the function of proton pumps. This decreases the quantity of acid produced by the stomach.
No. S-Ppi 40 mg Tablets prevents excess production of stomach acid causing acid reflux and heartburn. If blood is coming in your stool or mucous immediately contact the doctor.
Yes. S-Ppi 40 mg Tablets can alter certain medical tests like neuroendocrine tumours (secretin stimulation test), and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostics test contact your doctor.
It is very unlikely that taking one or two extra doses by accident will cause any problems. However, you should check with your doctor if you have taken too much and have are feeling sweaty, have a fast heartbeat, are feeling sleepy.
There's no firm evidence to suggest that taking S-Ppi 40 mg Tablets will reduce fertility in either men or women. However, speak to your doctor if you're trying to get pregnant and do as advised.
You can eat and drink normally while taking S-Ppi 40 mg Tablets . However, you should avoid foods that seem to make your indigestion worse, such as rich, spicy and fatty foods. You should also cut down on caffeinated drinks, such as tea, coffee and cola, as well as alcohol.
No. Gas and acidity are two different common discomforts. Acidity is caused when improper functioning of the valve (sphincter) is located at the junction of the stomach and food pipe. As a result stomach acid backflows and enters the upper part of the food pipe causing heartburn. On the other hand, gas is the result of the digestion of the food and drinks eliminating gases like carbon dioxide, hydrogen, nitrogen, methane, etc. from the body.
Prolonged intake of S-Ppi 40 mg Tablets may lead to atrophic gastritis (inflammation of stomach cells), Vitamin B12 deficiency and weakening of bones or osteoporosis (loss of calcium, magnesium and vitamin D). Your doctor may prescribe calcium, vitamin D or haemoglobin enhancing medications to cope with long term side effects.
S-Ppi 40 mg Tablets should be used in children only if prescribed by the doctor. Please consult the doctor before giving S-Ppi 40 mg Tablets to children.
S-Ppi 40 mg Tablets should be taken an hour before meals.
S-Ppi 40 mg Tablets is usually taken on an empty stomach, first thing in the morning. If you take S-Ppi 40 mg Tablets twice a day, take 1 dose in the morning and 1 dose in the evening.
Yes, S-Ppi 40 mg Tablets can be taken with domperidone if prescribed by the doctor.
Do not discontinue S-Ppi 40 mg Tablets without consulting your doctor. To treat your condition effectively, take S-Ppi 40 mg Tablets for the duration prescribed by the physician.
Yes, S-Ppi 40 mg Tablets is safe to use if prescribed by the doctor.
S-Ppi 40 mg Tablets can be taken with ranitidine if prescribed by the doctor. No interactions were found between both the medicines.
If you miss a dose of S-Ppi 40 mg Tablets take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.
S-Ppi 40 mg Tablets might cause side effects like headache, diarrhoea, nausea, abdominal pain, and vomiting. Consult the doctor if the side effects persist or worsen.
Consult the doctor before taking other medicines while using S-Ppi 40 mg Tablets to prevent interactions. Let the doctor know if you are taking blood thinners, antifungal agents, anti-HIV drugs, anti-viral drugs, iron supplements, antibiotics, cardiac medicines and anti-cancer drugs.
No, you should take S-Ppi 40 mg Tablets on an empty stomach, at least one hour before eating, as food can reduce how much of the medicine your body absorbs. Talk to your doctor or pharmacist if you have questions about the timing of your medication.
Esomeprazole may begin to provide some symptom relief within 1 to 2 hours, but it can take up to 2 to 4 days of consistent, daily use to reach its full acid-reducing effect. If your symptoms do not improve, talk to your doctor.
While S-Ppi 40 mg Tablets is highly effective, taking it long-term (especially for more than a year) can increase the risk of side effects like low magnesium, vitamin B12 deficiency, and bone fractures. Your doctor will prescribe it for the shortest time necessary; talk to your doctor about your treatment duration.
No, you should swallow the capsule or tablet whole. Crushing, chewing, or breaking it can destroy the special coating that protects the medicine from being deactivated by your stomach acid. If you have difficulty swallowing, talk to your doctor or pharmacist for alternative options.
Although alcohol does not directly stop S-Ppi 40 mg Tablets from working, alcohol can irritate your stomach lining and worsen your acid reflux or heartburn symptoms. For best results, it is highly recommended to limit or avoid alcohol; talk to your doctor for advice.
Weight gain is not a common or direct side effect of S-Ppi 40 mg Tablets . However, because the medicine relieves stomach pain and acid reflux, you may find it easier or more comfortable to eat, which could indirectly lead to weight changes. If you experience sudden or unexplained weight changes, talk to your doctor.
Mild, short-term diarrhoea can sometimes occur. However, if you develop severe, watery, or persistent diarrhoea accompanied by stomach cramps and fever, stop taking the medicine and call your doctor immediately, as this could be a sign of a serious bacterial infection. Talk to your doctor before taking any anti-diarrhoea medicine.
Yes, in most cases you can safely take an occasional antacid for rapid, temporary relief while waiting for S-Ppi 40 mg Tablets to take full effect. However, you should space them out and discuss this with your doctor or pharmacist first to ensure there are no specific issues with your treatment plan.

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Reference

  1. Drugs.com Clinical Review Team. Esomeprazole Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. National Health Service (NHS). Esomeprazole - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Electronic Medicines Compendium (EMC). Pil.3002 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  4. U.S. Food and Drug Administration (FDA). 021153S056,021957S023,022101S020Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  5. Esomeprazole [Prescribing Information]. 2014. [Accessed on 28 Mar. 2019]Check here
  6. Ema.Esomeprazole.PIL.[Accessed on 20 Nov 2025]Check here
  7. Dailymed. Esomeprazole.[Accessed on 20 Nov 2025]Check here

Country of origin

India

Manufacturer/Marketer address

Peninsula Chambers, Peninsula Corporate Park, G.K Marg, Lower Parel (West), Mumbai - 400013, Maharashtra, INDIA.
Other Info - SPP0004

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