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compositionComposition:ROMIPLOSTIM-250MCG
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Prescription Medicine
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Romplio 250 powder for Injection 1's belongs to the class of platelet-stimulating agents used in the treatment of idiopathic thrombocytopenic purpura. This medicine works by promoting platelet formation by activating the thrombopoietin receptor, thus helps treat the condition. Common side effects include headache, joint pain, dizziness, trouble sleeping, muscle tenderness or weakness, and indigestion.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

ROMIPLOSTIM-250MCG

Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Romplio 250 powder for Injection 1's

Romplio 250 powder for Injection 1's is a prescription medicine used to treat low blood platelet counts in adults and children with chronic immune thrombocytopenia (ITP). It is prescribed when other treatments, such as corticosteroids or surgery to remove the spleen, have not worked well enough. The primary medical purpose of this treatment is to raise your platelet count to a safer level, which directly helps prevent serious bleeding episodes.

This medicine is typically given as a weekly injection, and staying consistent with your schedule is vital for keeping your platelet levels stable. Since it is given as an injection under the skin, it does not matter if you take it with or without food. Making certain lifestyle adjustments, such as avoiding high-impact physical activities, can also help protect you from bruising and bleeding while undergoing treatment.

While using Romplio 250 powder for Injection 1's, you may experience mild side effects like headaches or joint pain. However, it is crucial to consult your doctor immediately if you experience severe symptoms such as sudden shortness of breath, swelling in your legs, or signs of an allergic reaction.

Before starting this medicine, tell your doctor if you have a history of blood clots, bone marrow problems, or blood cancers. Do not take this if you are allergic to any of its ingredients or have a known sensitivity to proteins derived from Escherichia coli.

Using this medicine alongside blood thinners or other platelet-boosting drugs can significantly affect how it works, which is why a complete medication review is necessary. Talk to your doctor or pharmacist if you are pregnant, planning to become pregnant, breastfeeding, or if you are caring for an elderly patient who may be more sensitive to the medication's effects.

Uses of Romplio 250 powder for Injection 1's

Your doctor may prescribe Romplio 250 powder for Injection 1's to help manage the following conditions:

  • Immune Thrombocytopenia (ITP): Romplio 250 powder for Injection 1's helps increase the number of platelets in patients with chronic ITP, lowering the risk of bruising and severe bleeding when other therapies have failed.

Key Benefits

When used as directed as part of your treatment plan, Romplio 250 powder for Injection 1's may provide the following benefits:

  • Helps increase platelet counts: May raise platelet levels to a safer range in people with chronic immune thrombocytopenia (ITP).
  • Helps reduce the risk of bleeding: By increasing platelet counts, it may lower the risk of bruising and bleeding episodes associated with low platelets.
  • Supports everyday activities: As platelet counts improve, you may feel more confident carrying out daily activities with a lower risk of bleeding from minor injuries.
  • May reduce the need for other treatments: In some people, successful treatment may reduce the need for rescue medicines or platelet transfusions, as determined by their doctor.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Romplio 250 powder for Injection 1's will be administered by a nurse or doctor.
  • Do not self-administer.

How Romplio 250 powder for Injection 1's Works

Romplio 250 powder for Injection 1's contains romiplostim, a thrombopoietin receptor agonist. This means it works like thrombopoietin, a natural hormone that tells your bone marrow to produce platelets. After it is injected under the skin, romiplostim attaches to thrombopoietin receptors, which are proteins found on the cells in your bone marrow that develop into platelets. This stimulates the bone marrow to produce more platelets. As more platelets are produced and released into the bloodstream, platelet counts increase. Because the response varies from person to person, your doctor will monitor your platelet count regularly and adjust your dose if needed.
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Alcohol

Caution

You are recommended not to consume alcohol along with Romplio 250 powder for Injection 1's to avoid unpleasant side effects.

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Pregnancy

Caution

Romplio 250 powder for Injection 1's is not recommended in pregnancy unless indicated by the doctor. Please consult your doctor if you are pregnant or planning to conceive.

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Breast Feeding

Unsafe

Breast-feeding must be avoided during treatment with Romplio 250 powder for Injection 1's. Please consult your doctor if you have any concerns.

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Driving

Caution

Romplio 250 powder for Injection 1's may cause dizziness. Hence, it is recommended not to drive or operate machinery until you are mentally alert.

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Liver

Caution

Romplio 250 powder for Injection 1's is not recommended particularly if you have a history of chronic liver disease/conditions. Please consult your doctor if you have any concerns

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Kidney

Caution

Limited information was available for the usage of Romplio 250 powder for Injection 1's in patients suffering from kidney illness. Please consult your doctor if you have any concerns. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Romplio 250 powder for Injection 1's is not recommended for children less than one year of age.

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Heart

Caution

Romplio 250 powder for Injection 1's should be administered with caution in patients with heart problems. Therefore, please talk to your doctor before receiving Romplio 250 powder for Injection 1's.

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Geriatrics

Caution

Romplio 250 powder for Injection 1's should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of Romplio 250 powder for Injection 1's

In case of an overdose, seek immediate medical attention. An overdose can cause your platelet counts to rise to dangerously high levels, which significantly increases the risk of serious blood clots.

Diet & Lifestyle Advise

  • Reduce your risk of injury: Avoid contact sports and activities that increase the risk of falls, cuts, or bruises while your platelet count is low.
  • Protect your mouth and skin: Use a soft-bristled toothbrush and an electric razor to help reduce the risk of bleeding.
  • Check with your doctor before taking new medicines: Avoid aspirin, ibuprofen, and other non-steroidal anti-inflammatory drugs (NSAIDs) unless recommended by your doctor, as they may increase the risk of bleeding.
  • Limit alcohol: Limit or avoid alcohol, as it may increase the risk of bleeding and affect your body's ability to produce healthy blood cells.
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How Soon It Starts Working

The time required for Romplio 250 powder for Injection 1's to start to work: Romplio 250 powder for Injection 1's ideally shows its action within 4 to 9 days after administration. The time for which the effects of Romplio 250 powder for Injection 1's last: The effect of Romplio 250 powder for Injection 1's lasts for 28 days.

What if you forget to take Romplio 250 powder for Injection 1's

If you miss a scheduled injection of Romplio 250 powder for Injection 1's, contact your doctor or healthcare provider immediately to schedule your next dose. Do not take a double dose to make up for a missed one.

Storage

• Store Romplio 250 powder for Injection 1's in a refrigerator between 2°C and 8°C (36°F to 46°F).

Drug Warnings

  • Keep your appointments: Attend all scheduled blood tests and follow-up visits so your doctor can monitor your platelet count and adjust your dose when needed.
  • Use the medicine exactly as prescribed: Do not change your dose or stop treatment unless your doctor tells you to, as your platelet count may fall after stopping treatment.
  • Watch for blood clots: Consult your doctor right away if you develop sudden chest pain, shortness of breath, swelling or pain in a leg, or sudden weakness or difficulty speaking.
  • Know the signs of an allergic reaction: Seek immediate medical attention if you develop a rash, swelling of your face, lips, tongue, or throat, or difficulty breathing after the injection.

verifiedApollotooltip
  • Blood thinners (like warfarin, heparin, or aspirin): Combining these with Romplio 250 powder for Injection 1's can complicate your bleeding risk management. Your doctor will monitor your blood clotting closely.
  • Other medicines for ITP: Using this medicine alongside other treatments that raise platelet levels may cause your platelet counts to rise too high, increasing clotting risks.

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verifiedApollotooltip

No clinically significant food interactions are known with Romplio 250 powder for Injection 1's when used as directed.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[PLATELET STIMULATING AGENTS]

FAQs

Romplio 250 powder for Injection 1's belongs to the class of platelet-stimulating agents and is primarily used to treat adults with chronic immune thrombocytopenia (ITP). It is generally recommended only for patients whose platelet counts remain low despite treatment with corticosteroids, immunoglobulins, or splenectomy, rather than as an initial treatment immediately after diagnosis.
Romplio 250 powder for Injection 1's contains Romiplostim, which promotes platelet formation by activating the thrombopoietin receptor. Thus Romplio 250 powder for Injection 1's lowers the risk of bleeding episodes in diseases like immune thrombocytopenia and other associated conditions.
Immune thrombocytopenia is an autoimmune disorder in which the immune system misidentifies platelets as foreign bodies and destroys them. It can occur due to a virus, vaccination, or certain drugs. But the origin is unknown in the majority of cases.
Idiopathic thrombocytopenic purpura is typically diagnosed with blood tests such as complete blood count and antiplatelet-antibody test.
Romplio 250 powder for Injection 1's is not approved to treat thrombocytopenia caused by Myelodysplastic syndrome (MDS) or any other cause of thrombocytopenia apart from chronic ITP.
Yes, some patients or their caregivers can inject Romplio 250 powder for Injection 1's at home. However, this is only recommended after you have received thorough, professional training from your healthcare provider. Talk to your doctor to see if home injection is appropriate for you.
If you stop taking this medicine, your platelet count is likely to drop back to its original low levels, usually within 2 weeks. This sudden drop increases your risk of bleeding, so you should never stop treatment without consulting your doctor.
No, Romplio 250 powder for Injection 1's does not cure chronic immune thrombocytopenia (ITP). It is a long-term treatment that helps manage the condition by keeping your platelet counts at a safer level to prevent bleeding. Talk to your doctor for more details on managing chronic ITP.
It is best to limit or avoid alcohol while using this medicine. Alcohol can affect your liver and also interfere with your blood's natural ability to clot, which can increase your overall risk of bleeding. Talk to your doctor or pharmacist about safe limits.
You will typically need weekly blood tests when you start taking this medicine so your doctor can find the correct dose. Once your platelet counts stabilise, these tests may be done less frequently, but regular monitoring is still essential.
There is limited clinical data on the safety of this medicine in pregnant women. If you are pregnant, planning to become pregnant, or breastfeeding, you must talk to your doctor to weigh the potential benefits against the risks before starting treatment.
Yes, because Romplio 250 powder for Injection 1's stimulates platelet production, it can sometimes cause platelet counts to rise too high, which increases the risk of blood clots. Your doctor will monitor your blood levels closely to keep your clotting risks as low as possible.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase Iii, New Delhi - 110020.
Other Info - ROM0223

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