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compositionComposition:ERYTHROPOIETIN-6000IU
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Prescription Medicine
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RENOCEL 6000IU INJECTION is used to treat anaemia (deficiency of red blood cells) associated with chronic kidney disease, cancer chemotherapy, and drug-induced anaemia. It contains erythropoietin, a glycoprotein that stimulates the bone marrow to increase the production of red blood cells. This medicine may cause side effects such as vomiting, headache, body aches, diarrhoea, fatigue, and stomach upset. Before starting RENOCEL 6000IU INJECTION, talk to your physician if you have any allergies or other pre-existing medical conditions to avoid potential interactions.

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Written By ,
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

ERYTHROPOIETIN-6000IU

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About RENOCEL 6000IU INJECTION

RENOCEL 6000IU INJECTION is a prescription injection used to treat anaemia, a condition where your body does not have enough healthy red blood cells. It is commonly prescribed for individuals living with long-term kidney disease, cancer patients undergoing chemotherapy, or patients scheduled for major surgeries to reduce the need for blood transfusions.

This medicine is injected either under the skin or directly into a vein, typically one to three times a week or every few weeks as prescribed. Because it is given as an injection, food does not affect how it works. Incorporating iron-rich foods like dark leafy greens and lean meats into your daily diet is a vital lifestyle habit that supports your treatment, as your body requires iron to build new blood cells.

While using it, you may experience mild side effects such as high blood pressure, headaches, or mild pain at the injection site. However, you must contact your doctor immediately if you experience serious side effects, such as sudden weakness, severe chest pain, shortness of breath, or a sudden, severe headache.

Before starting this treatment, talk to your doctor if you have a history of high blood pressure, heart disease, or blood clots. Do not take this if you have high blood pressure that is not controlled, or if you have ever had a severe allergic reaction to this medicine or similar red-blood-cell-stimulating treatments.

This medicine may interact with other therapies, so it is important to avoid alcohol and smoking, which can worsen blood pressure or circulation issues during your treatment. If you are pregnant, breastfeeding, or an older adult, you should consult your healthcare provider to discuss safe usage. This medicine should only be used in children under the care of a specialist. The dose and monitoring schedule are different from those used in adults. 

Uses of RENOCEL 6000IU INJECTION

Your doctor may recommend this injection to help manage the following conditions:

  • Anaemia from chronic kidney disease: It helps by stimulating your bone marrow to produce more red blood cells when your kidneys can no longer make enough of the natural hormone.
  • Anaemia caused by cancer chemotherapy: It helps rebuild your red blood cell count during cancer treatments, helping to relieve extreme tiredness and reducing the need for blood transfusions.
  • Anaemia in patients scheduled for surgery: It helps boost your red blood cell levels before major, non-heart surgeries to reduce the risk of needing blood transfusions during or after the procedure.

Key Benefits

When taken consistently as directed, this injection may provide the following physiological benefits:

  • Helps improve energy levels: By increasing your red blood cell count, this medicine helps your body deliver more oxygen to its tissues. This may reduce fatigue and improve your energy, making everyday activities easier
  • May reduce the need for blood transfusions: By stimulating your body to produce more red blood cells, this medicine may help reduce the need for blood transfusions and the risks associated with repeated transfusions.
Side effects of Renocel 6000iu Injection
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
  • Weight loss without physical activity needs immediate medical attention.
  • Get a physical examination and blood tests done to identify factors causing weight loss that could be related to metabolism and thyroid function.
  • Avoid smoking and alcohol intake as it can alter your liver condition and increase your weight loss.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of weight loss.
  • Talk to your dietician and consume food which can maintain ideal weight.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Administer RENOCEL 6000IU INJECTION subcutaneously as instructed by the doctor. Pinch a fold of skin using your finger and thumb and inject the prescribed dose into the fold.
  • Do not inject into red or bruised areas.

How RENOCEL 6000IU INJECTION Works

RENOCEL 6000IU INJECTION works by mimicking a natural hormone made by healthy kidneys. This hormone acts as a chemical messenger that travels to your bone marrow—the soft centre of your bones where blood cells are made. Once it arrives, it signals your bone marrow to start producing more red blood cells. Since red blood cells carry oxygen from your lungs to the rest of your body, having more of them relieves the symptoms of anaemia, such as extreme fatigue, feeling cold, and shortness of breath.
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Alcohol

Consult your doctor

Please consult a doctor, as it is unknown whether it is safe to consume alcohol with RENOCEL 6000IU INJECTION.

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Pregnancy

Consult your doctor

Limited data is available on the effect of RENOCEL 6000IU INJECTION in pregnancy. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving RENOCEL 6000IU INJECTION. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Limited data is available on the effect of RENOCEL 6000IU INJECTION on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving RENOCEL 6000IU INJECTION. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Consult your doctor

It is not known if RENOCEL 6000IU INJECTION affects your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before receiving RENOCEL 6000IU INJECTION. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

If you have a history of kidney disease, inform your doctor before receiving RENOCEL 6000IU INJECTION.

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Children

Consult your doctor

The safety of RENOCEL 6000IU INJECTION in children is not known. Please consult the doctor.

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Heart

Caution

RENOCEL 6000IU INJECTION can generally be used in patients with heart problems, but only under close medical supervision.

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Geriatrics

Safe if prescribed

RENOCEL 6000IU INJECTION is generally safe for geriatric individuals. Please consult your doctor if you have any concerns.

What if I have taken an overdose of RENOCEL 6000IU INJECTION

If you suspect an overdose or have injected too much of this medicine, seek immediate medical attention.

Diet & Lifestyle Advise

  • Eat iron-rich foods: Your body needs iron to build red blood cells. Include foods like lean meats, poultry, beans, spinach, and iron-fortified cereals in your meals as advised by your doctor or dietitian.
  • Monitor your blood pressure daily: Since this medicine can raise your blood pressure, keep a daily log of your readings and share them with your healthcare team.
  • Stay well-hydrated: Drink plenty of fluids throughout the day, unless your doctor has placed you on a fluid restriction due to kidney issues.
  • Take prescribed vitamin supplements: Your doctor may recommend that you take iron, vitamin B12, or folic acid supplements to support the production of red blood cells. Do not start any new supplements without consulting your doctor first.
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How Soon It Starts Working

The time required for RENOCEL 6000IU INJECTION to start to work: The time required for RENOCEL 6000IU INJECTION to show its action is unknown. The time for which the effects of RENOCEL 6000IU INJECTION last: The duration of action for RENOCEL 6000IU INJECTION is unknown.

What if you forget to take RENOCEL 6000IU INJECTION

If you miss a dose of injection, talk to your doctor or pharmacist for advice on when to take your next injection. Do not inject a double dose to make up for a missed one.

Storage

• Store it in the refrigerator between 2°C and 8°C (36°F to 46°F). • Do not freeze this medicine, and do not use it if it has been frozen.
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Check the medicine before use: Always check the expiration date on the package before using the injection.
  • Handle the injection carefully: Do not shake the vial or pre-filled syringe, as this may damage the medicine.
  • Rotate injection sites: Change your injection site each time between the thighs, abdomen, or upper arms to help reduce skin irritation or thickening.
  • Use a new needle each time: Never reuse needles or syringes. Dispose of them safely in a designated sharps container after use.
  • Attend follow-up tests: Keep all scheduled blood test appointments so your doctor can monitor your red blood cell levels and adjust your treatment if needed.
  • Choose a healthy injection site: Do not inject into skin that is tender, bruised, red, hard, scarred, or has stretch marks.
  • Seek emergency medical help: if you develop a severe allergic reaction, stroke, hypertensive crisis, or signs of pure red cell aplasia (PRCA) while receiving this medicine. 

Drug-Drug Interactions

verifiedApollotooltip
  • Cyclosporine: It may affect how cyclosporine (an immune-system-suppressing drug) works in your body. Your doctor may need to monitor your blood levels of this drug more closely.
  • Other blood-stimulating medicines: Combining it with other medicines that boost red blood cell production can raise your blood counts too high, increasing your risk of stroke or heart attack.

 

ErythropoietinThalidomide
Severe
ErythropoietinCarfilzomib
Severe

Drug-Drug Interactions

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ErythropoietinThalidomide
Severe
How does the drug interact with Renocel 6000iu Injection:
Taking thalidomide with Renocel 6000iu Injection may increase the risk or severity of thromboembolism(a circulating blood clot that gets stuck and causes an obstruction).

How to manage the interaction:
Although taking Renocel 6000iu Injection and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
ErythropoietinCarfilzomib
Severe
How does the drug interact with Renocel 6000iu Injection:
Carfilzomib can cause serious blood clots and taking it alongside Renocel 6000iu Injection may enhance the risk.

How to manage the interaction:
Co-administration of Renocel 6000iu Injection with Carfilzomib can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain, breathing difficulty, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ErythropoietinPomalidomide
Severe
How does the drug interact with Renocel 6000iu Injection:
Pomalidomide can cause serious blood clots and taking it alongside Renocel 6000iu Injection may enhance the risk.

How to manage the interaction:
Co-administration of Renocel 6000iu Injection with Pomalidomide can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain, breathing difficulty, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
ErythropoietinLenalidomide
Severe
How does the drug interact with Renocel 6000iu Injection:
Combining Renocel 6000iu Injection with Lenalidomide can increase the risk of Thrombosis(formation of a blood clot ).

How to manage the interaction:
Although there is an interaction between Renocel 6000iu Injection and Lenalidomide, it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with RENOCEL 6000IU INJECTION when used as directed. 
 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ERYTHROPOIESIS STIMULATING AGENTS (ESAs)]

FAQs

RENOCEL 6000IU INJECTION is used in the treatment of anaemia (lower red blood cell count) associated with renal disease, anaemia related to cancer chemotherapy, and drug-induced anaemia.
RENOCEL 6000IU INJECTION contains erythropoietin, a glycoprotein which stimulates the bone marrow to increase the production of red blood cells.
RENOCEL 6000IU INJECTION may cause side effects such as vomiting, headache, body aches, diarrhoea, stomach upset, and injection site reactions. If these side effects persist or worsen, seek medical attention.
Store RENOCEL 6000IU INJECTION at temperatures between 2°C and 8°C. Do not freeze or shake it excessively. Protect from light. Keep it out of reach of children.
Before using RENOCEL 6000IU INJECTION, inform your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding. Also, inform your doctor about your health condition and if you are taking other medicines, vitamins, or supplements.
Yes, you can inject it at home once your healthcare provider has trained you on how to prepare and inject it safely. Do not attempt to inject it yourself until you feel completely comfortable with the process. Talk to your doctor or pharmacist if you have any doubts.
This medicine signals your bone marrow to produce more red blood cells, which requires a large amount of iron. If your iron stores are low, the medicine will not work effectively. Talk to your doctor about whether you need an iron supplement.
If it was left at room temperature, check the package insert or contact your pharmacist immediately to see if it is still safe to use. Never freeze the medicine or use it if it has been exposed to extreme heat.
Yes, this medicine can increase the risk of serious blood clots, heart attacks, or strokes, especially if your red blood cell count rises too quickly or too high. Your doctor will monitor your blood closely to keep your levels in a safe range. Talk to your doctor if you experience sudden pain or swelling.
You should only use it during pregnancy if your doctor decides that the benefits clearly outweigh the potential risks to the baby. Always inform your healthcare provider if you are pregnant or planning to become pregnant. Talk to your doctor for personalised advice.
Shaking the vial can break down the delicate protein molecules in the medicine, making it completely inactive and ineffective. Always handle the vial gently and roll it between your hands if it needs mixing. Talk to your pharmacist if you suspect a vial has been shaken.
Your doctor will likely order blood tests once or twice a week when you first start treatment, and then less frequently once your red blood cell levels stabilise. These tests are critical to ensure your dose is safe and effective. Talk to your doctor to understand your test schedule.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - REN0201

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