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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Regestrone CR 10 mg Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, it may be used in the treatment of breast cancer. It contains Norethisterone, which works by restoring the hormone levels in the body. In some cases, this medicine may cause side effects such as unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

NORETHISTERONE-10MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Regestrone CR 10 mg Tablet

Regestrone CR 10 mg Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Endometriosis is a disorder in which the uterus's tissue lining (endometrium) grows on the ovaries, bowel, or tissues lining the pelvis.

Regestrone CR 10 mg Tablet contains Norethisterone, which mimics the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining.

Common side effects include unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, diarrhoea, headache, breast pain, and tenderness. Most of these side effects do not require medical attention. However, if the side effects persist, please consult your doctor.

If you are allergic to Regestrone CR 10 mg Tablet or any other medicines, please tell your doctor. Regestrone CR 10 mg Tablet is not recommended for pregnant women as it may harm the unborn baby. If you are breastfeeding, consult a doctor before taking Regestrone CR 10 mg Tablet . It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Regestrone CR 10 mg Tablet .

Uses of Regestrone CR 10 mg Tablet

Regestrone CR 10 mg Tablet is used to treat endometriosis. The detailed uses of Regestrone CR 10 mg Tablet are as follows:

  • Menstrual Cycle Regulation: Regestrone CR 10 mg Tablet is commonly used to regulate irregular menstrual cycles or to induce menstruation in women experiencing amenorrhea (absence of periods).
  • Management of Endometriosis: Regestrone CR 10 mg Tablet is also effective in managing endometriosis, a condition where uterine-like tissue grows outside the uterus, leading to pain and irregular bleeding.
  • Support in Hormone Replacement Therapy: In postmenopausal women, Regestrone CR 10 mg Tablet is often combined with estrogen therapy to prevent endometrial hyperplasia (thickening of the uterine lining), which can result from estrogen use alone.
  • Relieve Menstrual problems: Regestrone CR 10 mg Tablet is sometimes prescribed to alleviate symptoms of premenstrual syndrome (PMS) and to provide relief from excessive bleeding or pain during menstruation.

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Directions for Use

  • Regestrone CR 10 mg Tablet can be taken with or without food, or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Regestrone CR 10 mg Tablet as a whole with a glass of water.
  • Do not chew, crush or break it.

Medicinal Benefits

  • Regestrone CR 10 mg Tablet contains Norethisterone, a synthetic hormone that mimics the activity of the natural hormone progesterone.
  • It restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps treat menstrual disorders.
  • Regestrone CR 10 mg Tablet is also used in the treatment of breast cancer.

How Regestrone CR 10 mg Tablet Works

Regestrone CR 10 mg Tablet contains Norethisterone that works by mimicking the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Storage

• Store in a cool and dry place away from sunlight.• Keep Regestrone CR 10 mg Tablet out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Regestrone CR 10 mg Tablet

Take Regestrone CR 10 mg Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include nausea, vomiting, breast enlargement and vaginal bleeding. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • If you are allergic to Regestrone CR 10 mg Tablet or any other medicines, please tell your doctor.
  • Regestrone CR 10 mg Tablet is not recommended for pregnant women as it may harm an unborn baby.
  • If you are breastfeeding, consult a doctor before taking Regestrone CR 10 mg Tablet .
  • It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Regestrone CR 10 mg Tablet .
  • You are advised to stop smoking while taking Regestrone CR 10 mg Tablet as it may increase the risk of adverse effects.
  • If you are about to undergo any surgery, please inform your doctor that you are taking Regestrone CR 10 mg Tablet as it may increase the effect of certain anesthetics.
  • If you experience sudden shortness of breath, rapid heartbeat, sudden, severe, sharp pain in the chest, or cough up blood, stop taking Regestrone CR 10 mg Tablet and consult a doctor immediately as these might be signs of a blood clot in the lungs.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Regestrone CR 10 mg Tablet:
Coadministration of Regestrone CR 10 mg Tablet and Mycophenolic acid can decrease the levels and effects of Regestrone CR 10 mg Tablet.

How to manage the interaction:
There could be a possible interaction between Mycophenolic acid and Regestrone CR 10 mg Tablet, but they can be taken together if your doctor has prescribed them. However, if you experience hot flashes, vaginal dryness, or abnormal bleeding consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Regestrone CR 10 mg Tablet:
Co-administration of Regestrone CR 10 mg Tablet with Bosentan can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
Taking Regestrone CR 10 mg Tablet with Bosentan together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Regestrone CR 10 mg Tablet:
Coadministration of Regestrone CR 10 mg Tablet with Topiramate can reduce the blood levels and effects of norethindrone in the body. This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Taking Regestrone CR 10 mg Tablet and topiramate together can result in an interaction; it can be taken if your doctor has advised it. However, if you notice any symptoms of abnormal bleeding, hot flashes or vaginal dryness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Regestrone CR 10 mg Tablet:
Coadministration of Regestrone CR 10 mg Tablet with Tizanidine can cause drowsiness, confusion, slow heart rate, shallow breathing, feeling light-headed, fainting.

How to manage the interaction:
Taking Regestrone CR 10 mg Tablet with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteroneEtretinate
Severe
How does the drug interact with Regestrone CR 10 mg Tablet:
Using Etretinate and Regestrone CR 10 mg Tablet together can cause severe, birth defects. Never use etretinate if you are pregnant. Both a primary and a secondary form of birth control must be used together and for at least 3 years after stopping therapy.

How to manage the interaction:
Although taking Regestrone CR 10 mg Tablet and Etretinate together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs, make sure to contact your doctor right away. These symptoms may be related to your birth control. Do not stop using any medications without a doctor's advice.
NorethisteroneBexarotene
Severe
How does the drug interact with Regestrone CR 10 mg Tablet:
Coadministration of Bexarotene and Regestrone CR 10 mg Tablet together can decrease the effectiveness of norethindrone and increase the risk of unintended pregnancy.

How to manage the interaction:
Combining Bexarotene with Regestrone CR 10 mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneFosphenytoin
Severe
How does the drug interact with Regestrone CR 10 mg Tablet:
Coadministration of Regestrone CR 10 mg Tablet with Fosphenytoin can reduces the blood levels and effects of Regestrone CR 10 mg Tablet .

How to manage the interaction:
Taking Regestrone CR 10 mg Tablet with Fosphenytoin together can result in an interaction, but it can be taken if your doctor has advised it. If you experience symptoms of abnormal bleeding while using birth control, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Regestrone CR 10 mg Tablet:
Coadministration of Regestrone CR 10 mg Tablet and primidone can reduce the blood levels and effects of Regestrone CR 10 mg Tablet and increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Regestrone CR 10 mg Tablet and Primidone, they can be taken together if prescribed by a doctor. However, if you experience abnormal bleeding, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneTelaprevir
Severe
How does the drug interact with Regestrone CR 10 mg Tablet:
Using Telaprevir and Regestrone CR 10 mg Tablet together can increase risk of unintended pregnancy and decrease the effectiveness of norethindrone.

How to manage the interaction:
Combining Telaprevir with Regestrone CR 10 mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneAmprenavir
Severe
How does the drug interact with Regestrone CR 10 mg Tablet:
Coadministration of Amprenavir and Regestrone CR 10 mg Tablet together may reduce amprenavir effects.

How to manage the interaction:
Combining Amprenavir with Regestrone CR 10 mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid fried and processed foods.
  • Include fiber-rich foods like whole grains, fruits, and vegetables in your diet.
  • Avoid refined carbohydrates that are high in sugars.
  • Replace animal proteins (like eggs, fish, and meat) with vegetable protein sources (nuts, seeds, and beans).
  • Avoid drinking excess alcohol or caffeinated drinks as they can worsen the symptoms.
  • Maintain a healthy weight, do moderate exercise regularly.
  • Avoid smoking and alcohol intake.

Habit Forming

No

Therapeutic Class

PROGESTIN

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Alcohol

Consult your doctor

The interaction of Regestrone CR 10 mg Tablet with alcohol is unknown. Please consult a doctor before consuming alcohol while using Regestrone CR 10 mg Tablet .

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Pregnancy

Unsafe

Regestrone CR 10 mg Tablet is a category X pregnancy drug and is not recommended for use during pregnancy as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

Regestrone CR 10 mg Tablet is given to breastfeeding women only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Safe if prescribed

Regestrone CR 10 mg Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Unsafe

Regestrone CR 10 mg Tablet is not recommended if you have liver disease. However, if you have any concerns regarding this, please consult a doctor.

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Kidney

Caution

Take Regestrone CR 10 mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Regestrone CR 10 mg Tablet is not recommended for use in children under 18 years.

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Heart

Regestrone CR 10 mg Tablet should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Regestrone CR 10 mg Tablet .

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Geriatrics

Unsafe

Regestrone CR 10 mg Tablet is generally not recommended for elderly patients due to an increased risk of side effects and reduced effectiveness.

FAQs

Regestrone CR 10 mg Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, Regestrone CR 10 mg Tablet may be used in the treatment of breast cancer.

Regestrone CR 10 mg Tablet contains Norethisterone, a synthetic hormone that mimics the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Regestrone CR 10 mg Tablet may be used to delay periods. Regestrone CR 10 mg Tablet keeps progesterone levels high and prevents shedding of the womb lining. However, please consult a doctor before using Regestrone CR 10 mg Tablet .

Regestrone CR 10 mg Tablet may increase the risk of a blood clot in the veins of the leg, especially if you are overweight, smoke, or have a history of a blood clot in the lungs or veins, repeated miscarriage or have major surgery, serious injury, or systemic lupus erythematosus (autoimmune disease). Therefore, please inform your doctor if you have any of these conditions before taking Regestrone CR 10 mg Tablet .

You are not recommended to take Regestrone CR 10 mg Tablet with rifampicin as it may decrease the levels of Regestrone CR 10 mg Tablet in blood and reduce its effectiveness. However, please consult a doctor before taking Regestrone CR 10 mg Tablet with other medicines.

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - REG0157

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