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Rapilif-M 50 Tablet 15's is used for the treatment of Benign prostatic hyperplasia (BPH), a condition in men that causes the enlargement of the prostate gland. It contains Mirabegron and Silodosin. Mirabegron works by reducing the activity of an overactive bladder and treats related symptoms. Silodosin works by relaxing the muscles around the bladder exit and prostate gland. Thus, it makes it easier to pass urine and helps relieve urinary symptoms.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Rapilif-M 50 Tablet 15's

Rapilif-M 50 Tablet 15's is an oral medicine prescribed to treat lower urinary tract symptoms caused by an enlarged prostate, also known as benign prostatic hyperplasia, combined with an overactive bladder. Rapilif-M 50 Tablet 15's helps ease the discomfort of having a weak urine flow, straining to urinate, and feeling a sudden, uncontrollable urge to go. It is designed to target both the physical blockage and bladder muscle instability to make urination easier.

To get the best results, you must take Rapilif-M 50 Tablet 15's consistently every day at the same time. You should always take Rapilif-M 50 Tablet 15's with food, preferably with the same meal each day, to help your body absorb it properly. Incorporating lifestyle adjustments, such as limiting caffeine and performing pelvic floor exercises, can further improve your urinary symptoms.

While taking Rapilif-M 50 Tablet 15's, some people may experience mild side effects like dizziness, dry mouth, or a harmless condition where semen flows backward into the bladder during ejaculation. However, you should consult your doctor immediately if you experience severe dizziness, fainting, a fast or irregular heartbeat, or a painful erection that lasts for several hours.

Before starting Rapilif-M 50 Tablet 15's, talk to your doctor if you have a history of heart rhythm problems, high blood pressure, or kidney or liver disease. Do not take this if you have severe kidney failure, severe liver damage, or if you are preparing to undergo cataract surgery.

Rapilif-M 50 Tablet 15's can interact with blood pressure medications, certain antifungal drugs, and heart medications, which can increase your risk of severe side effects. Avoid drinking alcohol while taking Rapilif-M 50 Tablet 15's, as it can significantly worsen dizziness and lightheadedness. Elderly individuals should use Rapilif-M 50 Tablet 15's with caution due to an increased risk of falls, and should always consult a doctor before starting treatment.

Uses of Rapilif-M 50 Tablet 15's

Rapilif-M 50 Tablet 15's is used in the treatment of Benign prostatic hyperplasia (BPH). The detailed uses of Rapilif-M 50 Tablet 15's are as follows:

  • Benign Prostatic Hyperplasia (BPH) with overactive bladder symptoms: Rapilif-M 50 Tablet 15's helps by relaxing the muscles in the prostate and bladder neck, making it easier to pass urine, while simultaneously relaxing the bladder muscle to reduce the sudden, urgent need to urinate.

Key Benefits

Rapilif-M 50 Tablet 15's helps improve urinary symptoms associated with an enlarged prostate and overactive bladder by relaxing the muscles of the prostate, bladder neck, and bladder. It supports better bladder control and makes urination more comfortable.

Benefits may include:

  • Helps improve urine flow and reduces difficulty in passing urine.
  • Relieves symptoms such as straining, weak urine stream, and incomplete bladder emptying.
  • Helps reduce urinary urgency, frequent urination, and episodes of urge incontinence.
  • Decreases nighttime urination, helping promote better sleep.
  • Improves bladder control and overall urinary function.
  • Enhances comfort and quality of life by effectively managing urinary symptoms when used as prescribed.

Directions for Use

  • Rapilif-M 50 Tablet 15's can be taken with or without food, as advised by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow the whole Rapilif-M 50 Tablet 15's with a glass of water.
  • Do not chew, crush, or break it.

How Rapilif-M 50 Tablet 15's Works

Rapilif-M 50 Tablet 15's contains Mirabegron and Silodosin. • Mirabegron: It is a beta-3 adrenergic receptor agonist that helps relax the bladder muscle while the bladder is filling. This increases the amount of urine the bladder can hold and helps reduce symptoms such as urinary urgency, frequent urination, and urge incontinence. • Silodosin: It is an alpha-blocker that relaxes the smooth muscles of the prostate and the bladder neck. This reduces resistance to urine flow, making it easier to start urination, empty the bladder more completely, and improve urinary flow.
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Alcohol

Consult your doctor

The interaction of Rapilif-M 50 Tablet 15's with alcohol is unknown. If you have any concerns, discuss them with your doctor.

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Pregnancy

Not applicable

Rapilif-M 50 Tablet 15's is recommended for use in men.

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Breast Feeding

Not applicable

Rapilif-M 50 Tablet 15's is recommended for use in men.

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Driving

Caution

Rapilif-M 50 Tablet 15's may cause dizziness in some people. Therefore, avoid driving if you feel dizzy after taking Rapilif-M 50 Tablet 15's.

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Liver

Consult your doctor

If you are suffering from liver diseases or conditions, inform your doctor before taking Rapilif-M 50 Tablet 15's. Your doctor may adjust the dose as necessary.

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Kidney

Consult your doctor

If you are suffering from kidney diseases or conditions, inform your doctor before taking Rapilif-M 50 Tablet 15's. Your doctor may adjust the dose as necessary.

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Children

Unsafe

Rapilif-M 50 Tablet 15's is not recommended for children and adolescents below 18 years as there is no relevant use for this age group.

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Heart

Caution

Rapilif-M 50 Tablet 15's should be taken with caution if you have heart problems. It may raise blood pressure and increase the risk of arrhythmias, so always consult your doctor before starting this medication.

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Geriatrics

Caution

Rapilif-M 50 Tablet 15's can be used by geriatric patients but only under medical supervision. Older adults may be more sensitive to side effects like dizziness, blood pressure changes, or urinary issues, so regular monitoring is essential.

What if I have taken an overdose of Rapilif-M 50 Tablet 15's

If you suspect an overdose, seek immediate medical attention or contact a poison control center. Symptoms of an overdose may include severe dizziness, fainting, or a very rapid heartbeat.

Diet & Lifestyle Advise

  • Limit bladder irritants: Reduce your intake of caffeine, alcohol, and artificial sweeteners, as they can irritate the bladder and worsen urinary urgency.
  • Manage evening fluid intake: Avoid drinking large amounts of fluids in the evening or close to bedtime to help reduce nighttime urination.
  • Practice pelvic floor exercises: Perform pelvic floor muscle exercises (Kegel exercises) regularly to help strengthen the muscles that control urination.
  • Increase your fiber intake: Eat a high-fiber diet to help prevent constipation, as a full bowel can put pressure on the bladder and worsen BPH symptoms.
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How Soon It Starts Working

The time required for Rapilif-M 50 Tablet 15's to start to work: Rapilif-M 50 Tablet 15's ideally shows its action within few hours after administration. The time for which the effects of Rapilif-M 50 Tablet 15's last: The duration of action for Rapilif-M 50 Tablet 15's is not clinically established.

What if you forget to take Rapilif-M 50 Tablet 15's

If you miss a dose, take it with food as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store Rapilif-M 50 Tablet 15's at controlled room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Stand up slowly: Rise gradually from a sitting or lying position, especially when starting Rapilif-M 50 Tablet 15's or after the first few doses, to help reduce the risk of dizziness, lightheadedness, or fainting. If possible, take your first dose when you can rest at home, and sit or lie down if you feel dizzy until the feeling passes.
  • Inform healthcare providers before eye surgery: Tell your eye surgeon that you are taking Rapilif-M 50 Tablet 15's before cataract surgery, as silodosin may cause Intraoperative Floppy Iris Syndrome (IFIS) during the procedure.
  • Monitor your blood pressure: Check your blood pressure regularly, particularly when starting treatment, as mirabegron may increase blood pressure in some people.
  • Use caution during activities requiring alertness: Avoid driving, operating machinery, or performing hazardous tasks until you know how Rapilif-M 50 Tablet 15's affects you, as it may cause dizziness or drowsiness.
  • Inspect Rapilif-M 50 Tablet 15's before use: Check the packaging before each use. Do not take the tablets or capsules if the seals are broken or if Rapilif-M 50 Tablet 15's shows signs of moisture damage, discoloration, or other visible changes.

verifiedApollotooltip
  • Alpha-blockers or blood pressure medicines (e.g., tamsulosin, amlodipine): Taking these medicines alongside Rapilif-M 50 Tablet 15's may cause an excessive drop in blood pressure, increasing the risk of dizziness or fainting.
  • Antifungal medicines (e.g., ketoconazole, itraconazole): These medicines may increase silodosin levels in the body and raise the risk of side effects.
  • HIV medicines (e.g., ritonavir): These medicines may increase silodosin levels in the body and increase the risk of side effects.
  • Antiarrhythmic medicines (e.g., amiodarone, quinidine): These medicines may interact with the mirabegron component and increase the risk of heart rhythm problems. Your doctor may monitor you more closely.
  • P-glycoprotein (P-gp) inhibitors (e.g., cyclosporine): These medicines may increase silodosin levels in the body and raise the risk of side effects. Your doctor may recommend avoiding this combination or adjusting your treatment.

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verifiedApollotooltip
  • Food: Take Rapilif-M 50 Tablet 15's with food, as food improves the absorption of the silodosin component and helps reduce the risk of side effects such as low blood pressure.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[BPH AGENTS]

FAQs

Rapilif-M 50 Tablet 15's is used for the treatment of Benign prostatic hyperplasia (BPH) complicated by overactive bladder with symptoms of urge urinary incontinence (involuntary leakage of urine), urgency, and frequency.
Rapilif-M 50 Tablet 15's contains Mirabegron and Silodosin. Mirabegron reduces the activity of an overactive bladder and treats related symptoms. Silodosin relaxes the muscles around the bladder exit and prostate gland. Thus, it makes it easier to pass urine and helps relieve urinary symptoms.
Low blood pressure, especially when starting to take Rapilif-M 50 Tablet 15's, may cause dizziness when standing up suddenly from a sitting or lying position. Therefore, to avoid such effects, it is advised to stand up slowly from a sitting or lying position. Regular blood pressure monitoring is recommended at the beginning of therapy to reduce the possibility of such effects.
The best time to take Rapilif-M 50 Tablet 15's may vary based on the health condition of an individual. However, take Rapilif-M 50 Tablet 15's at the same time each day for best results as advised by the doctor.
Consult the doctor before taking Rapilif-M 50 Tablet 15's if you have any history of kidney disease as dose adjustment may be necessary.
The side effects of Rapilif-M 50 Tablet 15's include constipation, nausea, dizziness, increased heart rate, abnormal ejaculation, urinary tract infections, and runny or blocked nose. Most of these side effects resolve gradually over time on their own. However, consult the doctor if any of these side effects persist or worsen.
Rapilif-M 50 Tablet 15's is primarily intended to treat symptoms of Benign Prostatic Hyperplasia (BPH). While it may have a secondary effect on blood pressure, it is not intended to manage blood pressure. Please check with your doctor for information or to discuss your blood pressure treatment plan.
You should take sildenafil along with Rapilif-M 50 Tablet 15's with caution, as both medications can cause low blood pressure (hypotension), leading to fainting, dizziness, or light-headedness. It’s important to consult your doctor before using them together to avoid potential interactions.
It is best to avoid or strictly limit alcohol while taking Rapilif-M 50 Tablet 15's. Alcohol can worsen side effects like dizziness, lightheadedness, and low blood pressure. Talk to your doctor for advice tailored to your health.
Yes, silodosin in Rapilif-M 50 Tablet 15's can cause retrograde ejaculation, a harmless condition in which semen flows backward into the bladder instead of leaving the body during orgasm. This may result in little or no semen being released during ejaculation. The effect is temporary and usually resolves after Rapilif-M 50 Tablet 15's is stopped. Talk to your doctor if you have any concerns or if it affects your quality of life.
Many people notice an improvement in urine flow within about 1 to 2 weeks of starting Rapilif-M 50 Tablet 15's. However, the full benefits for overactive bladder symptoms, such as urgency and frequent urination, may take several weeks and sometimes up to 4 to 8 weeks of regular treatment. Continue taking Rapilif-M 50 Tablet 15's as prescribed and talk to your doctor if your symptoms do not improve or become worse.
No, Rapilif-M 50 Tablet 15's is specifically formulated and approved for men experiencing symptoms associated with an enlarged prostate. It is not recommended for use in women. Talk to your doctor for appropriate bladder treatments for women.
Inform your eye surgeon (ophthalmologist) well in advance of your cataract surgery that you are taking Rapilif-M 50 Tablet 15's. The silodosin component can cause your pupil to become floppy during surgery, and your surgeon will need to take special precautions. Talk to your doctor about whether to pause Rapilif-M 50 Tablet 15's.
You should not stop taking Rapilif-M 50 Tablet 15's without consulting your doctor first. Stopping Rapilif-M 50 Tablet 15's abruptly can cause your urinary flow issues and bladder urgency to return. Talk to your doctor before making any changes.
The mirabegron component in Rapilif-M 50 Tablet 15's can cause an increase in blood pressure in some patients. It is important to have your blood pressure checked regularly while taking Rapilif-M 50 Tablet 15's. Talk to your doctor if you have a history of high blood pressure.
No, you must swallow Rapilif-M 50 Tablet 15's whole. Crushing, chewing, or breaking Rapilif-M 50 Tablet 15's can affect how it is absorbed in your body and increase the risk of severe side effects. Talk to your doctor or pharmacist if you have trouble swallowing pills.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Medline Plus. Silodosin [Revised in 15th October 2016]. [Accessed on 12th June 2026]Check here
  2. Mfll0042 00. [Accessed on 02 Jun. 2026]Check here
  3. Ministry of Health and Family Welfare. National Formulary of India (NFI) 2021. 6th ed. New Delhi, India: IPC; 2021. Clinical Drug Monographs: Rapilif M 25 Kit

Country of origin

India

Manufacturer/Marketer address

142 Ab, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra.
Other Info - RAP0247
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