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  3. Ranolaz 500 Tablet 10's

Ranolaz 500 Tablet 10's, Pack of 10 TABLETS
Ranolaz 500 Tablet 10's, Pack of 10 TABLETS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Ranolaz 500 Tablet is used alone or with other medicines to treat angina pectoris. It helps prevent any further attack of angina by making the heart work more efficiently, and it is used as an add-on to existing treatment in patients whose disease is not adequately controlled by other medicines for angina pectoris, such as beta-blockers or calcium antagonists, or in patients who cannot take these medicines. In some cases, it may cause side effects such as constipation, dizziness, headache, or feeling sick. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

RANOLAZINE-500MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Ranolaz 500 Tablet

Ranolaz 500 Tablet is used to treat angina pectoris. Angina pectoris is discomfort in the chest or chest pain, which generally occurs due to coronary artery disease (CAD) when the heart and its muscles are not receiving enough oxygen and blood.

Ranolaz 500 Tablet contains Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels, through which calcium ions normally enter the cells.

You may sometimes experience constipation, dizziness, headache, or feeling sick. Most of these side effects of Ranolaz 500 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

You can take Ranolaz 500 Tablet with food or as advised by your doctor. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Depending on your medical conditions, your doctor will advise the dose and duration of Ranolaz 500 Tablet .

Do not take Ranolaz 500 Tablet if you are allergic to any component in this medicine. Ranolaz 500 Tablet should not be stopped even if you feel better for the best results, as it prevents any future harm. If you stop taking the Ranolaz 500 Tablet on your own, your chest pain can come back in more severe form. If you plan to get pregnant or are pregnant or breastfeeding, please consult your doctor to avoid any unwanted harm to the baby. 

Uses of Ranolaz 500 Tablet

Ranolaz 500 Tablet used in the treatment of Angina Pectoris. The detailed use of Ranolaz 500 Tablet is as follows:

  • Treatment of Angina Pectoris: Ranolaz 500 Tablet is used in the treatment of angina pectoris by improving oxygen supply to the heart muscle and enhancing cardiac efficiency, particularly in areas with fixed epicardial lesions, thereby decreasing chest pain episodes and improving patient quality of life.

Directions for Use

  • Ranolaz 500 Tablet can be taken with or without food.
  • It is usually taken twice daily at the same time each day or as prescribed by your doctor.
  • Swallow Ranolaz 500 Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

Medicinal Benefits

  • Ranolaz 500 Tablet is prescribed for treating angina. Ranolaz 500 Tablet is an anti-anginal medication used to treat angina pectoris.
  • It reduces sodium ions' flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called ‘sodium-dependent calcium channels’ through which calcium ions normally enter the cells.
  • This medicine reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract.
  • Ranolaz 500 Tablet helps improve blood flow to the heart muscle and relieve the symptoms of angina pectoris.

How Ranolaz 500 Tablet Works

The active substance in Ranolaz 500 Tablet is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels, through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Ranolaz 500 Tablet is thought to help the heart relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Ranolaz 500 Tablet

Do not take more than the prescribed dose of Ranolaz 500 Tablet as it may cause overdose. The symptoms of overdose include nausea, vomiting, confusion, dizziness, double vision, fainting, difficulty speaking, uncontrollable shaking of a part of the body, hallucinations and burning, pain, numbness, or tingling in any part of the body. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Ranolaz 500 Tablet if you are allergic to any component in this medicine.
  • Ranolaz 500 Tablet should not be stopped even if you feel better for the best results, as it prevents any future harm. If you stop taking the Ranolaz 500 Tablet on your own, your chest pain can come back in a more severe form.
  • Ranolaz 500 Tablet should be taken with caution in liver disease, kidney disease, or heart problems.
  • Inform your doctor if you are pregnant, planning for pregnancy, or breastfeeding before taking Ranolaz 500 Tablet .
  • Also, grapefruit juice should be avoided while taking Ranolaz 500 Tablet .
  • As a precautionary measure, avoid junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery.
  • Do regular exercise to avoid abdominal heaviness.

Diet & Lifestyle Advise

  • Maintain a healthy lifestyle by exercising regularly, maintaining weight, and eating a healthy diet.
  • If you suffer from kidney or liver disease, please inform your doctor before taking the Ranolaz 500 Tablet .
  • Alcohol consumption along with Ranolaz 500 Tablet should be avoided as it may cause excessive drowsiness and increase muscle pain.

Habit Forming

No

Therapeutic Class

ANTIANGINALS

Ranolaz 500 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Safe if prescribed

Ranolaz 500 Tablet does not have any reported interaction; hence, if you experience any difficulty, discuss with your doctor.

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Pregnancy

Unsafe

Ranolaz 500 Tablet should not be used when pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Ranolaz 500 Tablet .

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Breast Feeding

Consult your doctor

Ranolaz 500 Tablet should not be used in nursing mothers. Please consult the doctor if you have any concerns regarding this.

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Driving

Safe if prescribed

Ranolaz 500 Tablet does not have any reported interaction; hence, in case you experience any difficulty, discuss with your doctor.

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Liver

Caution

Ranolaz 500 Tablet to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Ranolaz 500 Tablet to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Ranolaz 500 Tablet is not recommended for children below the age of 18. The safety and effectiveness of Ranolaz 500 Tablet have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

Have a query?

FAQs

Ranolaz 500 Tablet is used alone or with other medicines to treat angina pectoris.

The active substance in Ranolaz 500 Tablet is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called sodium-dependent calcium channels through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Ranolaz 500 Tablet is thought to help the heart to relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

No, Ranolaz 500 Tablet does not stop acute attacks (sudden attacks) of angina, but Ranolaz 500 Tablet helps prevent a new attack.

No, alcohol should not be taken with Ranolaz 500 Tablet as it may lead to unwanted side effects and increase angina attacks.

Yes, smoking (tobacco) decreases the efficacy of Ranolaz 500 Tablet , especially when taken for angina (chest pain), so it should be avoided while taking Ranolaz 500 Tablet .

Yes, Ranolaz 500 Tablet can cause an upset stomach when taken empty stomach. So, to avoid it, Ranolaz 500 Tablet should be taken with a meal for best results.

Yes, Ranolaz 500 Tablet can cause drowsiness. If you feel excessively sleepy, please consult your doctor for better advice.

Some major side effects include a rapid, pounding, or irregular heartbeat, difficulty breathing, and fainting. If you encounter any of these symptoms, contact your doctor immediately.

Do not take more than the prescribed dose of Ranolaz 500 Tablet as it may cause overdose. The symptoms of overdose include nausea, vomiting, confusion, dizziness, double vision, fainting, difficulty speaking, uncontrollable shaking of a part of the body, hallucinations and burning, pain, numbness, or tingling in any part of the body. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Ranolaz 500 Tablet may increase the blood levels and effects of metoprolol. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects.

Ranolaz 500 Tablet might raise metformin levels, increasing the risk of lactic acidosis. If you are prescribed ranolazine while taking metformin, discuss it with a healthcare physician. They may offer a lesser dose of metformin as a safer alternative.

You can take it if prescribed by the doctor. However, limit simvastatin to 20 mg once daily in individuals taking any dose of Ranolaz 500 Tablet .

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - RAN0027

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 8, 2025 | 1:48 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.6442.pdf
  2. https://medlineplus.gov/druginfo/meds/a606015.html
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021526s029lbl.pdf
  4. https://www.ema.europa.eu/en/documents/product-information/ranexa-epar-product-information_en.pdf

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