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  3. Psorid 100 Capsule 5's

Psorid 100 Capsule 5's, Pack of 5 CAPSULES
Psorid 100 Capsule 5's, Pack of 5 CAPSULES
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Psorid 100 Capsule is used to prevent organ transplant rejection. It is also used to treat inflammation and pain associated with psoriasis and rheumatoid arthritis. This medicine contains cyclosporine, which works by suppressing the immune system. It also helps reduce rapid skin cell growth, pain, and inflammation. It may sometimes cause common side effects such as headaches, vomiting, nausea, loss of appetite, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Synonym :

CYCLOSPORIN

Composition :

CYCLOSPORINE-100MG

Manufacturer/Marketer :

Biocon Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Psorid 100 Capsule

Psorid 100 Capsule belongs to a group of medications called 'immunosuppressants,' primarily used to prevent organ rejection after a transplant. It is also used to treat symptoms associated with psoriasis and rheumatoid arthritis.

Psorid 100 Capsule contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and lowers pain and inflammation in the joints.

Psorid 100 Capsule may cause side effects like headaches, vomiting, nausea, loss of appetite and diarrhoea. Most of these side effects do not require medical attention and resolve over time. However, consult your doctor if the side effects persist or worsen.

To treat your condition effectually, continue taking Psorid 100 Capsule for as long as your doctor has prescribed. Inform your doctor about your health condition and any medications you are taking to help rule out any potential/unpleasant side effects.

Uses of Psorid 100 Capsule

Psorid 100 Capsule is used to prevent organ rejection and treat psoriasis and rheumatoid arthritis. The detailed uses of Psorid 100 Capsule are as follows:

  • Treatment of Organ Transplant Rejection: Psorid 100 Capsule is used in the prevention of organ transplant rejection after liver, kidney, pancreas, lungs, heart, skin, and bone marrow transplants.
  • Treatment of Psoriasis: Psorid 100 Capsule is used in the treatment of psoriasis. It helps reduce rapid skin cell growth and inflammation caused by psoriasis.
  • Treatment of Rheumatoid Arthritis: Psorid 100 Capsule is used in the treatment of rheumatoid arthritis. It helps reduce pain and inflammation in the joints and slows down joint damage.

Directions for Use

  • Psorid 100 Capsule can be taken with or without food.
  • It is usually taken 2 times a day or as prescribed by your doctor.
  • Swallow Psorid 100 Capsule as a whole with a glass of water.
  • Do not crush, chew, or open it.

Medicinal Benefits

  • Psorid 100 Capsule suppresses the immune system to prevent the rejection of transplanted organs (e.g., kidney, liver, heart).
  • It is also used in bone marrow and stem cell transplantation to prevent graft rejection.
  • Psorid 100 Capsule helps control immune overactivity in various autoimmune conditions by blocking immune cells that attack the body’s own tissues.
  • It reduces rapid skin cell growth and inflammation in severe psoriasis, leading to clearer skin and symptom relief.
  • This medicine reduces joint pain, inflammation, and slows down joint damage in patients with active rheumatoid arthritis unresponsive to other therapies.
  • It may also be used to treat severe atopic dermatitis, especially in patients who do not respond adequately to topical treatments.
  • Helps manage severe inflammatory eye diseases that can threaten vision by reducing immune-mediated damage.
  • It is used in certain cases of nephrotic syndrome (a kidney disorder causing excess protein loss in urine), especially when other treatments fail.

How Psorid 100 Capsule Works

Psorid 100 Capsule contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and the production of interleukins (molecules involved in inflammation). Additionally, it also reduces pain and inflammation in the joints and slows down the joint damage caused by an overactive immune system.

Storage

• Store in a cool and dry place away from sunlight.• Keep Psorid 100 Capsule out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Psorid 100 Capsule
  • Get plenty of fresh air.
  • Take regular sips of a cold drink.
  • Take ginger containing foods like ginger tea and ginger biscuits.
  • Do not take heavy meals at a time, take small and frequent meals.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Using a cold compress may help relieve itching and inflammation associated with conjunctivitis.
  • A warm compress and washing the eyes with water can help with crusting on the eyelids.
  • Avoid wearing contact lens until you feel better; use spectacles instead.
  • Do not rub the eyes.
  • Practise good hand hygiene and avoid touching the eyes to prevent the spread of infection.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Increase protein intake by eating protein-rich foods like eggs, fish, lean meat, beans, and nuts to support nail strength.
  • Include biotin-rich foods like salmon, avocado, bananas, almonds, and whole grains in your diet to promote nail health.
  • Boost iron intake by consuming iron-rich foods like spinach, red meat, lentils, and fortified cereals to prevent iron deficiency.
  • Moisturize your nails and cuticles regularly by applying cuticle oil or hand cream multiple times a day.
  • Keep your nails short to reduce the risk of breakage and snagging.
  • Avoid biting your nails, as it can cause significant damage to your nails and cuticles.
  • Consider taking biotin supplements after consulting your doctor, as they may help strengthen brittle nails.

What if I have taken an overdose of Psorid 100 Capsule

Take Psorid 100 Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. Symptoms of overdose may include headache, drowsiness, vomiting, increased heart rate, and liver and kidney toxicity. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Psorid 100 Capsule if you are allergic to any of the components.
  • Let your doctor know before using Psorid 100 Capsule if you have/had liver or kidney problems, epilepsy, high blood pressure, low levels of magnesium, high levels of potassium, cancer, or infection.
  • Psorid 100 Capsule may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising.
  • Before taking Psorid 100 Capsule, inform your doctor if you have any type of cancer.
  • Consult your doctor before taking Psorid 100 Capsule if you are pregnant or planning for pregnancy.
  • Psorid 100 Capsule should not be taken by breastfeeding mothers as it passes into breast milk.
  • Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Drug-Drug Interactions

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CiclosporinCidofovir
Critical
CiclosporinPitavastatin
Critical

Drug-Drug Interactions

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CiclosporinCidofovir
Critical
How does the drug interact with Psorid 100 Capsule:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Psorid 100 Capsule with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
CiclosporinPitavastatin
Critical
How does the drug interact with Psorid 100 Capsule:
Coadministration of pitavastatin with Psorid 100 Capsule may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Pitavastatin with Psorid 100 Capsule is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
CiclosporinSimvastatin
Critical
How does the drug interact with Psorid 100 Capsule:
Combining Psorid 100 Capsule and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Psorid 100 Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
CiclosporinBosentan
Critical
How does the drug interact with Psorid 100 Capsule:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Psorid 100 Capsule with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinBaricitinib
Critical
How does the drug interact with Psorid 100 Capsule:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Psorid 100 Capsule with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinEverolimus
Severe
How does the drug interact with Psorid 100 Capsule:
Taking everolimus with cyclosporine may significantly increases the blood levels of everolimus.

How to manage the interaction:
Although taking everolimus and Psorid 100 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. In case you experience any side effects like persistent cough, fever, chills, mouth ulcers, paleness of skin, or unusual bleeding or bruising, or blood in stools or urine, consult a doctor. Do not stop using any medications without talking to a doctor.
CiclosporinCisapride
Severe
How does the drug interact with Psorid 100 Capsule:
Coadministration of cisapride with cyclosporine may significantly increase the blood levels of cisapride which may increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between cisapride and Psorid 100 Capsule, but it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
CiclosporinSulfadiazine
Severe
How does the drug interact with Psorid 100 Capsule:
Coadministration of sulfadiazine with Psorid 100 Capsule may increases the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between sulfadiazine and Psorid 100 Capsule, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
CiclosporinEtanercept
Severe
How does the drug interact with Psorid 100 Capsule:
When etanercept is taken with cyclosporine, it can increase the risk of infections.

How to manage the interaction:
Although taking etanercept and Psorid 100 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, contact a doctor immediately if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
CiclosporinAliskiren
Severe
How does the drug interact with Psorid 100 Capsule:
The combined use of aliskiren and Psorid 100 Capsule can significantly increase the blood levels and effects of aliskiren, which may lead to low blood pressure, hyperkalemia (high potassium levels) in the body. High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythms. If you are elderly, dehydrated, or have kidney disease, diabetes, or severe heart failure, you are more prone to develop hyperkalemia while taking these medications.

How to manage the interaction:
Taking aliskiren and Psorid 100 Capsule will lead to an interaction, they can be taken together if your doctor has prescribed them. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. It is advised to reduce intake of potassium-rich foods such as tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes, and potassium-containing salt substitutes.

Drug-Food Interactions

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CYCLOSPORINE-100MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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CYCLOSPORINE-100MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming grapefruit and grapefruit juice while taking Psorid 100 Capsule can increase the effects of Psorid 100 Capsule. Avoid consuming grapefruit and grapefruit juice while taking Psorid 100 Capsule.

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieve joint stiffness. Gentle activities, such as 20-30 minutes of walking or swimming, would be helpful.
  • Practising yoga may also help improve joint flexibility and manage pain.
  • Maintain a healthy weight by engaging in regular low-impact exercises and eating a balanced diet.
  • Get adequate sleep, as rest can help reduce inflammation and swelling.
  • Follow heat or cold therapy by applying a cold or hot compress to the joints for 15-20 minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat foods rich in antioxidants, such as berries, spinach, kidney beans, and dark chocolate.
  • Foods containing flavonoids can help reduce inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Psorid 100 Capsule Substitute

Substitutes safety advice

Product Substitutes

bannner image

Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Psorid 100 Capsule. It could lead to increased dizziness and drowsiness.

bannner image

Pregnancy

Caution

It is not known whether Psorid 100 Capsule will harm an unborn baby. Inform your doctor if you are pregnant or plan to become pregnant.

bannner image

Breast Feeding

Unsafe

It is not recommended to take Psorid 100 Capsule while you are breastfeeding. Psorid 100 Capsule passes into breast milk.

bannner image

Driving

Caution

Drive or operate machinery only if you are alert.

bannner image

Liver

Caution

Take Psorid 100 Capsule only if prescribed by the doctor, especially if you are dealing with Liver diseases/conditions, as your doctor may adjust the dose as required.

bannner image

Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment before taking Psorid 100 Capsule.

bannner image

Children

Unsafe

Psorid 100 Capsule should not be given to children, as the efficacy and safety have not been established.

Have a query?

FAQs

Psorid 100 Capsule belongs to a group of medications called 'immunosuppressants,' primarily used to prevent organ transplant rejection after liver, kidney, pancreas, lungs, heart, skin, and bone marrow transplants. It is also used to treat symptoms associated with psoriasis and rheumatoid arthritis.

Psorid 100 Capsule acts as an immunosuppressant, which helps reduce pain and inflammation in the joints and prevent joint stiffness, thereby relieving rheumatoid arthritis.

If you miss a dose of Psorid 100 Capsule, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take the scheduled dose. Do not take a double dose to make up for a missed one.

Diarrhoea might be a side-effect of Psorid 100 Capsule. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in your stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Yes, using Psorid 100 Capsule may cause abnormal hair growth, although it does not affect everybody. Consult your doctor if you have any concerns.

Psorid 100 Capsule is known to decrease the immune system. As a result, it increases your risk of developing certain types of cancer, especially skin cancer. You should reduce your contact with sunlight and UV light by wearing suitable protective clothing. Sunscreen should be used regularly.

No, Psorid 100 Capsule is not a steroid. It is an immunosuppressant.

Yes, cyclosporine can cause weight gain. However, this is not a common side effect, and the amount of weight gain varies from person to person.

Yes, fatigue is a common side effect of cyclosporine. Many people who take cyclosporine report feeling tired or fatigued.

Psorid 100 Capsule is an immunosuppressant medication, meaning it weakens your immune system. This can make you more susceptible to infections and other health problems. Your doctor will likely order regular blood tests to monitor your health and ensure the medication is working effectively.

Psorid 100 Capsule has not been definitively linked to causing cancer. However, discussing any concerns you may have with your doctor is essential. They can provide personalized information about your health situation and why you take cyclosporine.

Common side effects of Psorid 100 Capsule may include headaches, vomiting, nausea, high blood pressure, increased hair growth, loss of appetite (feeling unwell and upset stomach), kidney disease, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Psorid 100 Capsule ideally should be given 12 hours apart. The capsules should be taken with water and swallowed whole. Grapefruit and grapefruit juice should be avoided, as they can increase ciclosporin levels in the blood.

The duration of Psorid 100 Capsule treatment varies depending on the underlying condition and individual response.

Always consult with your doctor or pharmacist before starting any new medications or supplements while taking Psorid 100 Capsule. They can help you identify potential interactions and recommend safe alternatives if necessary.

Yes, you can travel while taking cyclosporine. However, it's essential to plan and take necessary precautions. Ensure you have a sufficient supply of your medication, and be aware of any potential customs regulations or travel restrictions.

Generally, moderate exercise is safe while taking Psorid 100 Capsule. However, listening to your body and avoiding overexertion is essential, especially if you have any underlying health conditions.

Excessive alcohol consumption can increase the risk of side effects and interact with cyclosporine. It's best to limit alcohol intake or avoid it altogether while taking this medication.

Your doctor will determine the frequency of your blood tests based on your situation. However, regular monitoring is essential to ensure that cyclosporine works effectively and detects potential side effects.

If you miss a dose of Psorid 100 Capsule, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Some people may experience mood changes or anxiety while taking Psorid 100 Capsule. If you notice any changes in your mental health, it's important to talk to your doctor.

Psorid 100 Capsule occasionally causes blurred vision or eye irritation. If you experience any vision problems, contact your doctor.

Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.

Taking more than the recommended dosage does not provide additional benefit and can increase the risk of adverse effects.

Psorid 100 Capsule contains cyclosporine, an immunosuppressant.

Psorid 100 Capsule should not be given to children, as the efficacy and safety have not been established.

Country of origin

INDIA

Manufacturer/Marketer address

20th KM, Hosur Road, Electronic City, Bangalore, India - 560 100
Other Info - PSO0025

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 7, 2025 | 12:11 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/050715s035,050716s038lbl.pdf
  2. https://www.mayoclinic.org/drugs-supplements/cyclosporine-oral-route/description/drg-20075815
  3. https://medlineplus.gov/druginfo/meds/a601207.html
  4. https://www.drugs.com/disease-interactions/cyclosporine.html
  5. https://www.medicines.org.uk/emc/files/pil.5300.pdf
  6. https://www.webmd.com/drugs/2/drug-5645-9108/cyclosporine-oral/cyclosporine-oral/details

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