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compositionComposition:AMOXICILLIN-500MG+CLAVULANIC ACID-125MG
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Prescription Medicine
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Princiclav 625 mg Tablet 6's is used to treat bacterial infections of the ear, nose, throat, skin, bone, soft tissue, joints, urinary tract, and respiratory tract. It contains Amoxicillin and Clavulanic acid, which work by preventing the formation of bacterial cell covering, which is necessary for the survival of the bacteria. Thereby, it kills the bacteria. Also, it decreases bacterial resistance. In some cases, it may cause certain common side effects such as skin rashes, nausea, vomiting, bloating, and gas. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Dr. Aneela S , PhD, M Pharmacy
Reviewed By Dr. Syed Akram , MBBS, MD
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More about the Product

Composition :

AMOXICILLIN-500MG+CLAVULANIC ACID-125MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Princiclav 625 mg Tablet 6's

Princiclav 625 mg Tablet 6's is a prescription oral medication used to treat various bacterial infections in the body. It is commonly prescribed for infections of the lungs, ears, sinuses, skin, and urinary tract. It works by stopping the growth of bacteria causing the infection.

To get the best results, you must take Princiclav 625 mg Tablet 6's exactly as prescribed by your doctor, keeping your doses evenly spaced throughout the day. It is highly recommended to take this medication at the start of a meal to help your body absorb it better and prevent stomach irritation. Staying well-hydrated and resting during your treatment also supports your recovery.

While taking this medicine, you may experience mild side effects like a temporary upset stomach or loose stools. However, you should contact your doctor immediately if you experience severe watery diarrhea, yellow skin or eyes, or a skin rash. These can be signs of more serious complications that need prompt medical attention.

Talk to your doctor before taking Princiclav 625 mg Tablet 6's if you have kidney problems, liver issues, or a history of allergies to similar medications. Do not take this if you have had a severe allergic reaction to penicillin-type antibiotics or if you have previously experienced liver damage when taking this specific medication combination.

This medicine can interact with other treatments, such as certain gout medications or blood thinners, which may increase your risk of side effects. If you are pregnant, breastfeeding, or managing health conditions in your senior years, consult your healthcare provider to ensure this treatment is safe for you.

Uses of Princiclav 625 mg Tablet 6's

Princiclav 625 mg Tablet 6's is used to treat infections. The detailed uses of Princiclav 625 mg Tablet 6's are as follows: 

  • Sinus and Ear Infections: Clears bacterial blockages and inflammation in the nasal passages and middle ear.
  • Throat and Airway Infections: Treats certain bacterial infections of the respiratory tract, such as bacterial pneumonia, bacterial tonsillitis, and other susceptible airway infections
  • Urinary Tract Infections (UTIs): Targets and eliminates bacteria causing bladder or kidney infections.
  • Skin and Soft Tissue Infections: Stops bacterial spread in cuts, deep wounds, or severe skin infections.
    Dental Infections: Helps clear severe tooth abscesses and gum infections.
     

Key Benefits

Princiclav 625 mg Tablet 6's provides reliable, daily support to help you manage your health. This medicine brings several key health benefits:

  • Princiclav 625 mg Tablet 6's brings rapid relief by stopping the spread of infection, allowing your body's immune system to heal and recover.
  • Patients typically notice a reduction in fever, pain, and swelling within the first few days of starting the treatment. Because it contains a helper ingredient that shields the primary antibiotic from being destroyed by bacterial defenses, this medication is highly effective against stubborn bacteria that have become resistant to standard, single-ingredient antibiotics.
     

Directions for Use

Follow these steps to take Princiclav 625 mg Tablet 6's safely and effectively:

  • Take this medicine by mouth at the start of a light meal to reduce stomach upset and improve absorption.
  • Swallow tablets whole with a full glass of water. Do not crush, break, or chew them unless your pharmacist tells you otherwise.
  • If you are using the liquid suspension form, shake the bottle thoroughly before each dose and use a proper measuring syringe or spoon.
  • Even if your symptoms clear up after a few days, you must complete the entire course of treatment. Stopping too early can cause the infection to return and make the bacteria harder to treat in the future.

Always follow your doctor's exact instructions regarding how and when to take your medication.
 

How Princiclav 625 mg Tablet 6's Works

Princiclav 625 mg Tablet 6's is a combination medication containing two active components that work together to fight bacterial infections. The primary antibiotic component works by preventing bacteria from building their protective outer walls. Without this wall, the bacteria cannot survive and eventually burst and die. However, some bacteria produce special defense proteins (enzymes) that destroy antibiotics before they can work. The second active component in Princiclav 625 mg Tablet 6's acts as a shield. It blocks these destructive enzymes, protecting the primary antibiotic and allowing it to safely enter and destroy the bacteria.
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Alcohol

Caution

Limit or avoid consuming alcohol while taking Princiclav 625 mg Tablet 6's to prevent unpleasant side effects.

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Pregnancy

Caution

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

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Breast Feeding

Consult your doctor

This medication passes into breast milk. Consult your doctor before breast-feeding.

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Driving

Caution

Princiclav 625 mg Tablet 6's may cause dizziness. So, drive only if you are alert and omit driving and operating machinery if you feel dizzy.

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Liver

Caution

Princiclav 625 mg Tablet 6's to be taken with caution, especially if you have a history of liver diseases. Dose may have to be adjusted by your doctor.

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Kidney

Caution

Princiclav 625 mg Tablet 6's to be taken with caution, especially if you have a history of kidney diseases. Dose may have to be adjusted by your doctor.

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Children

Caution

The dose and duration may vary depending upon the child’s weight and the severity of the infection.

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Heart

Consult your doctor

Please consult your doctor before using Princiclav 625 mg Tablet 6's if you have pre-existing heart problems. Your doctor will prescribe Princiclav 625 mg Tablet 6's if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Princiclav 625 mg Tablet 6's to geriatric patients. Your doctor will prescribe Princiclav 625 mg Tablet 6's if the benefits outweigh the risks.

What if I have taken an overdose of Princiclav 625 mg Tablet 6's

Do not take more than the prescribed dose of Princiclav 625 mg Tablet 6's as it may cause overdose. The symptoms of overdose include diarrhoea, feeling or being sick and seizures (fits). If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Eat probiotic-rich foods: Consuming yogurt, kefir, or taking probiotic supplements can help replenish the friendly bacteria in your gut. Keep these foods or supplements spaced at least two hours apart from your medication dose.
  • Stay well-hydrated: Drink plenty of water throughout the day to support your kidneys as they process and clear the medication from your system.
  • Prioritise rest: Get extra sleep to help your body direct its energy toward fighting off the infection.
  • Avoid alcohol: Alcohol can irritate your stomach lining and put extra stress on your liver while you are recovering.
     
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How Soon It Starts Working

  • The time required for Princiclav 625 mg Tablet 6's to start to work: Princiclav 625 mg Tablet 6's ideally shows its action within 1 to 2 hours after administration.
  • The time for which the effects of Princiclav 625 mg Tablet 6's last: The effect of Princiclav 625 mg Tablet 6's lasts for 6 to 8 hours.

What if you forget to take Princiclav 625 mg Tablet 6's

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

Store dry tablets in their original packaging at room temperature, below 25°C (77°F), away from moisture, heat, and direct light. If you are using the liquid suspension, store it in the refrigerator between 2°C and 8°C (36°F to 46°F). Do not freeze it. Di

Drug Warnings

  • Always inspect the packaging before use; do not use the medicine if the seal is broken or if the tablets look damaged.
  • For liquid forms, never use a standard kitchen spoon to measure your dose, as it does not provide an accurate measurement.
  • Finish the entire bottle or pack exactly as directed, even if you feel completely better.
  • Contact your doctor immediately if you develop a new skin rash, joint pain, or a fever during or after your treatment.
     

verifiedApollotooltip
  • Blood thinners (such as warfarin): Princiclav 625 mg Tablet 6's can increase the effects of blood thinners, which may raise your risk of bleeding.
  • Gout medications (such as allopurinol): Taking these alongside Princiclav 625 mg Tablet 6's can significantly increase the risk of developing a skin rash.
  • Birth control pills: Current evidence suggests that amoxicillin-clavulanic acid is unlikely to significantly reduce the effectiveness of most hormonal contraceptives. However, if you experience vomiting or severe diarrhea while taking this medication, absorption of oral contraceptives may be affected. Consult your doctor or pharmacist if you have concerns.

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verifiedApollotooltip
  • Taking Princiclav 625 mg Tablet 6's at the start of a meal maximises how much medicine your body absorbs and significantly reduces the risk of an upset stomach.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Princiclav 625 mg Tablet 6's is used to treat bacterial infections of the ear, nose, throat, skin, bone, soft tissue, joints, urinary tract, and respiratory tract.
Princiclav 625 mg Tablet 6's contains Amoxicillin and Clavulanic acid. Amoxicillin works by preventing the formation of bacterial cell covering, which is necessary for the survival of the bacteria. Thereby, it kills the bacteria. Clavulanic acid works by decreasing bacterial resistance and enhancing the activity of amoxicillin against the bacteria. Together, Princiclav 625 mg Tablet 6's helps in treating bacterial infections.
No, this is an antibiotic medication. You need to complete the full course even if you start to feel better to prevent return of infection and resistance to Princiclav 625 mg Tablet 6's.
Princiclav 625 mg Tablet 6's does not treat a viral infection like the flu or a common cold. It is best to consult the doctor to know if you need Princiclav 625 mg Tablet 6's for your condition.
Princiclav 625 mg Tablet 6's may start to show its effects within a few hours after taking the medicine. However, you may begin to feel better after the first few days of treatment. If your symptoms do not improve or worsen, please contact your doctor.
Princiclav 625 mg Tablet 6's should be taken for the duration prescribed by your doctor based on the severity of your infection. Usually, it is taken every 8-12 hours.
Yes, Princiclav 625 mg Tablet 6's is generally safe when used as prescribed by your doctor to treat bacterial infections. Before taking this medicine, inform your doctor if you are allergic to any of its ingredients or have a history of jaundice associated with its use. Also let your doctor know if you have glandular fever, intestinal inflammation, seizures, liver or kidney problems, or difficulty passing urine regularly. Consult your doctor if you experience any unusual symptoms or have concerns while using Princiclav 625 mg Tablet 6's.
Yes, the use of Princiclav 625 mg Tablet 6's may reduce the effectiveness of hormonal contraceptives, such as birth control pills. This is because antibiotics like amoxicillin can affect the gut bacteria responsible for metabolizing contraceptive hormones, leading to lower hormone levels in the bloodstream. Please consult your doctor for alternative methods of preventing pregnancy or if you have any concerns while using this medication.
You should not exceed the recommended dose of Princiclav 625 mg Tablet 6's, as doing so may increase the risk of side effects, such as stomach upset, liver damage, and allergic reactions. It may also lead to antibiotic resistance. If you feel that the current dose is ineffective or your infection worsens, please consult your doctor. Your doctor may adjust your dose or recommend an alternative treatment to prevent resistance.
Princiclav 625 mg Tablet 6's should be stored at room temperature, away from direct sunlight. Keep it out of reach of children.
Princiclav 625 mg Tablet 6's may cause allergic reactions in some individuals. Common symptoms of an allergic reaction include rash, itching, swelling, and difficulty breathing or swallowing. People who are allergic to penicillin (one of its ingredients) or other antibiotics in the same class are more likely to experience an allergic reaction. It is important to seek immediate medical attention if any signs of an allergic reaction occur.
Princiclav 625 mg Tablet 6's does not commonly cause drowsiness as a side effect in some individuals. However, if you feel unusually tired after taking Princiclav 625 mg Tablet 6's, please consult your doctor.
Princiclav 625 mg Tablet 6's should be taken exactly as prescribed by your doctor. Typically, it should be swallowed as a whole with a glass of water. Do not crush, break, or chew it.
Do not take Princiclav 625 mg Tablet 6's unless your doctor advises if you are pregnant or nursing. Please consult your doctor, as they will evaluate the benefits and risks and provide guidance tailored to your situation.
The common side effects of Princiclav 625 mg Tablet 6's include skin rashes, nausea, vomiting, bloating, and gas. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Princiclav 625 mg Tablet 6's may interact with certain medications, such as anti-gout drugs (e.g., allopurinol, probenecid), anticoagulants (e.g., warfarin), anti-cancer drugs (e.g., methotrexate), and immunosuppressants (e.g., mycophenolate mofetil). To ensure safe treatment, it is essential to inform your doctor about all the medications you are currently using, including supplements and over-the-counter drugs. Your doctor can help manage potential interactions and provide personalized guidance.
If you overdose on Princiclav 625 mg Tablet 6's, seek immediate medical attention or go to your nearest emergency room. Overdose symptoms of Princiclav 625 mg Tablet 6's may include nausea, vomiting, skin rash, drowsiness, diarrhoea, stomach pain, and decreased urination.
It is best to take Princiclav 625 mg Tablet 6's at the start of a meal. This helps your body absorb the medication better and protects your stomach from irritation and nausea. Talk to your doctor or pharmacist if you struggle to take it with food.
While alcohol does not directly stop Princiclav 625 mg Tablet 6's from working, it can worsen side effects like stomach upset, dizziness, and dehydration. It is best to avoid alcohol until you have finished your treatment and recovered. Talk to your doctor or pharmacist for personalised advice.
Current evidence suggests that Princiclav 625 mg Tablet 6's is unlikely to significantly reduce the effectiveness of most hormonal birth control methods. However, if you experience vomiting or severe diarrhea during treatment, your contraceptive pill may not be absorbed properly. If you have concerns about contraception while taking this medicine, talk to your doctor or pharmacist.
No. You must finish the full course of treatment even if you feel completely healthy. Stopping the medication too early can leave surviving, stronger bacteria behind, causing the infection to return and become resistant to future treatment. Talk to your doctor if you have concerns.

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Reference

  1. Electronic Medicines Compendium (EMC). Pil.9127 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. National Health Service (NHS). Co Amoxiclav - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Augmentin Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Augmentin Tablets USP [Internet]. Accessdata.fda.gov. 2025 [Accessed on 7 July 2025]Check here
  5. Augmentin 625 mg Capsules - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 7 July 2025]Check here
  6. National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 23665637, Amoxicillin-Potassium Clavulanate Combination. [Accessed on 7 July 2025]Check here
  7. Drugbank.Amoxicillin.Drugbank [Accessed on 7 July 2025]Check here

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, India.
Other Info - PRI0314
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