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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Primacci-N 5 mg Tablet 10's is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, it may be used in the treatment of breast cancer. It contains Norethisterone, which works by restoring the hormone levels in the body. In some cases, this medicine may cause side effects such as unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

NORETHISTERONE-5MG

Manufacturer/Marketer :

Sudhir Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Primacci-N 5 mg Tablet 10's

Primacci-N 5 mg Tablet 10's is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Endometriosis is a disorder in which the uterus's tissue lining (endometrium) grows on the ovaries, bowel, or tissues lining the pelvis.

Primacci-N 5 mg Tablet 10's contains Norethisterone, which mimics the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining.

Common side effects include unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, diarrhoea, headache, breast pain, and tenderness. Most of these side effects do not require medical attention. However, if the side effects persist, please consult your doctor.

If you are allergic to Primacci-N 5 mg Tablet 10's or any other medicines, please tell your doctor. Primacci-N 5 mg Tablet 10's is not recommended for pregnant women as it may harm the unborn baby. If you are breastfeeding, consult a doctor before taking Primacci-N 5 mg Tablet 10's. It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Primacci-N 5 mg Tablet 10's.

Uses of Primacci-N 5 mg Tablet 10's

Primacci-N 5 mg Tablet 10's is used to treat endometriosis. The detailed uses of Primacci-N 5 mg Tablet 10's are as follows:

  • Menstrual Cycle Regulation: Primacci-N 5 mg Tablet 10's is commonly used to regulate irregular menstrual cycles or to induce menstruation in women experiencing amenorrhea (absence of periods).
  • Management of Endometriosis: Primacci-N 5 mg Tablet 10's is also effective in managing endometriosis, a condition where uterine-like tissue grows outside the uterus, leading to pain and irregular bleeding.
  • Support in Hormone Replacement Therapy: In postmenopausal women, Primacci-N 5 mg Tablet 10's is often combined with estrogen therapy to prevent endometrial hyperplasia (thickening of the uterine lining), which can result from estrogen use alone.
  • Relieve Menstrual problems: Primacci-N 5 mg Tablet 10's is sometimes prescribed to alleviate symptoms of premenstrual syndrome (PMS) and to provide relief from excessive bleeding or pain during menstruation.

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Directions for Use

  • Primacci-N 5 mg Tablet 10's can be taken with or without food, or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Primacci-N 5 mg Tablet 10's as a whole with a glass of water.
  • Do not chew, crush or break it.

Medicinal Benefits

  • Primacci-N 5 mg Tablet 10's contains Norethisterone, a synthetic hormone that mimics the activity of the natural hormone progesterone.
  • It restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps treat menstrual disorders.
  • Primacci-N 5 mg Tablet 10's is also used in the treatment of breast cancer.

How Primacci-N 5 mg Tablet 10's Works

Primacci-N 5 mg Tablet 10's contains Norethisterone that works by mimicking the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Storage

• Store in a cool and dry place away from sunlight.• Keep Primacci-N 5 mg Tablet 10's out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Primacci-N 5 mg Tablet 10's

Take Primacci-N 5 mg Tablet 10's only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include nausea, vomiting, breast enlargement and vaginal bleeding. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • If you are allergic to Primacci-N 5 mg Tablet 10's or any other medicines, please tell your doctor.
  • Primacci-N 5 mg Tablet 10's is not recommended for pregnant women as it may harm an unborn baby.
  • If you are breastfeeding, consult a doctor before taking Primacci-N 5 mg Tablet 10's.
  • It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking Primacci-N 5 mg Tablet 10's.
  • You are advised to stop smoking while taking Primacci-N 5 mg Tablet 10's as it may increase the risk of adverse effects.
  • If you are about to undergo any surgery, please inform your doctor that you are taking Primacci-N 5 mg Tablet 10's as it may increase the effect of certain anesthetics.
  • If you experience sudden shortness of breath, rapid heartbeat, sudden, severe, sharp pain in the chest, or cough up blood, stop taking Primacci-N 5 mg Tablet 10's and consult a doctor immediately as these might be signs of a blood clot in the lungs.

Drug-Drug Interactions

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NorethisteroneFosamprenavir
Severe

Drug-Drug Interactions

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NorethisteroneFosamprenavir
Severe
How does the drug interact with Primacci-N 5 mg Tablet:
Using norethindrone together with fosamprenavir may decrease the effects of fosamprenavir.

How to manage the interaction:
Taking Primacci-N 5 mg Tablet with Fosamprenavir together can result in an interaction, but it can be taken if your doctor has advised it. If you're taking birth control and experiencing any symptoms, it's important to reach out to a doctor right away. They can recommend other options that won't interfere with your medication. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Primacci-N 5 mg Tablet:
Co-administration of Primacci-N 5 mg Tablet with Bosentan can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
Taking Primacci-N 5 mg Tablet with Bosentan together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Primacci-N 5 mg Tablet:
Coadministration of Primacci-N 5 mg Tablet and primidone can reduce the blood levels and effects of Primacci-N 5 mg Tablet and increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Primacci-N 5 mg Tablet and Primidone, they can be taken together if prescribed by a doctor. However, if you experience abnormal bleeding, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Primacci-N 5 mg Tablet:
Eslicarbazepine may reduce the effects of Primacci-N 5 mg Tablet and its blood levels.

How to manage the interaction:
Although taking Eslicarbazepine and Primacci-N 5 mg Tablet results in an interaction, they can be taken together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Primacci-N 5 mg Tablet:
Coadministration of Primacci-N 5 mg Tablet with Dabrafenib can reduce the metabolism and decrease the levels of Primacci-N 5 mg Tablet in the body.

How to manage the interaction:
Taking Primacci-N 5 mg Tablet with Dabrafenib together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of hot flashes, vaginal dryness, or abnormal bleeding, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Primacci-N 5 mg Tablet:
Using Felbamate and Primacci-N 5 mg Tablet together can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
There may be a possibility of interaction between Primacci-N 5 mg Tablet and Felbamate, but it can be taken if prescribed by a doctor. If you notice any unusual symptoms like changes in your menstrual cycle, excessive bleeding, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
NorethisteroneRifapentine
Severe
How does the drug interact with Primacci-N 5 mg Tablet:
Combining Rifapentine and norethindrone reduces the blood levels and effects of norethindrone and increases the risk of bleeding and unintended pregnancy.

How to manage the interaction:
Although there is a possible interaction between Primacci-N 5 mg Tablet and Rifapentine, you can take these medicines together if prescribed by your doctor. If you're having any of these symptoms like unexpected bleeding, abnormal bleeding, it's important to reach out to a doctor right away. Do not discontinue any medications without consulting a doctor.
NorethisteroneEtretinate
Severe
How does the drug interact with Primacci-N 5 mg Tablet:
Using Etretinate and Primacci-N 5 mg Tablet together can cause severe, birth defects. Never use etretinate if you are pregnant. Both a primary and a secondary form of birth control must be used together and for at least 3 years after stopping therapy.

How to manage the interaction:
Although taking Primacci-N 5 mg Tablet and Etretinate together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs, make sure to contact your doctor right away. These symptoms may be related to your birth control. Do not stop using any medications without a doctor's advice.
How does the drug interact with Primacci-N 5 mg Tablet:
Coadministration of Primacci-N 5 mg Tablet with Rifabutin can reduce the blood levels and effects of norethindrone.This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Taking Primacci-N 5 mg Tablet with Rifabutin together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of abnormal bleeding, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteroneTelaprevir
Severe
How does the drug interact with Primacci-N 5 mg Tablet:
Using Telaprevir and Primacci-N 5 mg Tablet together can increase risk of unintended pregnancy and decrease the effectiveness of norethindrone.

How to manage the interaction:
Combining Telaprevir with Primacci-N 5 mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice may increase the blood levels of Primacci-N 5 mg Tablet. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Primacci-N 5 mg Tablet dose. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Primacci-N 5 mg Tablet dose.

Diet & Lifestyle Advise

  • Avoid fried and processed foods.
  • Include fiber-rich foods like whole grains, fruits, and vegetables in your diet.
  • Avoid refined carbohydrates that are high in sugars.
  • Replace animal proteins (like eggs, fish, and meat) with vegetable protein sources (nuts, seeds, and beans).
  • Avoid drinking excess alcohol or caffeinated drinks as they can worsen the symptoms.
  • Maintain a healthy weight, do moderate exercise regularly.
  • Avoid smoking and alcohol intake.

Habit Forming

No

Therapeutic Class

PROGESTIN

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Alcohol

Consult your doctor

The interaction of Primacci-N 5 mg Tablet 10's with alcohol is unknown. Please consult a doctor before consuming alcohol while using Primacci-N 5 mg Tablet 10's.

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Pregnancy

Unsafe

Primacci-N 5 mg Tablet 10's is a category X pregnancy drug and is not recommended for use during pregnancy as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

Primacci-N 5 mg Tablet 10's is given to breastfeeding women only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Safe if prescribed

Primacci-N 5 mg Tablet 10's usually does not affect your ability to drive or operate machinery.

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Liver

Unsafe

Primacci-N 5 mg Tablet 10's is not recommended if you have liver disease. However, if you have any concerns regarding this, please consult a doctor.

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Kidney

Caution

Take Primacci-N 5 mg Tablet 10's with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Primacci-N 5 mg Tablet 10's is not recommended for use in children under 18 years.

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Heart

Primacci-N 5 mg Tablet 10's should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Primacci-N 5 mg Tablet 10's.

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Geriatrics

Unsafe

Primacci-N 5 mg Tablet 10's is generally not recommended for elderly patients due to an increased risk of side effects and reduced effectiveness.

FAQs

Primacci-N 5 mg Tablet 10's is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, Primacci-N 5 mg Tablet 10's may be used in the treatment of breast cancer.

Primacci-N 5 mg Tablet 10's contains Norethisterone, a synthetic hormone that mimics the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Primacci-N 5 mg Tablet 10's may be used to delay periods. Primacci-N 5 mg Tablet 10's keeps progesterone levels high and prevents shedding of the womb lining. However, please consult a doctor before using Primacci-N 5 mg Tablet 10's.

Primacci-N 5 mg Tablet 10's may increase the risk of a blood clot in the veins of the leg, especially if you are overweight, smoke, or have a history of a blood clot in the lungs or veins, repeated miscarriage or have major surgery, serious injury, or systemic lupus erythematosus (autoimmune disease). Therefore, please inform your doctor if you have any of these conditions before taking Primacci-N 5 mg Tablet 10's.

You are not recommended to take Primacci-N 5 mg Tablet 10's with rifampicin as it may decrease the levels of Primacci-N 5 mg Tablet 10's in blood and reduce its effectiveness. However, please consult a doctor before taking Primacci-N 5 mg Tablet 10's with other medicines.

Country of origin

India

Manufacturer/Marketer address

2-3 SATKAR BHAVAN BADI OMTI, NEAR CLOCK TOWER, Jabalpur-482002, Madhya Pradesh, India
Other Info - PRI0803

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