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compositionComposition:POLYMYXIN B-500000IU
prescriptionPrescription Medicine
Polyxx Injection 1's

Polyxx Injection is used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. It contains Polymyxin B, which destroys bacterial cell membranes and kills infection-causing bacteria. Thereby, it helps treat bacterial infections. In some cases, Polyxx Injection may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

POLYMYXIN B-500000IU

Manufacturer/Marketer :

Celon Laboratories Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Polyxx Injection

Polyxx Injection belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms.

Polyxx Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

In some cases, Polyxx Injection may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Let the doctor know if you are allergic to any of the components in Polyxx Injection. Consult the doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Polyxx Injection

Polyxx Injection is used in the treatment of Bacterial infections. The detailed uses of Polyxx Injection are as follows:

  • Treat bloodstream infections: Polyxx Injection is effective against septicemia caused by resistant gram-negative bacteria such as Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli.
  • Manage meningitis: Polyxx Injection is administered intrathecally to treat bacterial meningitis, especially when caused by Pseudomonas aeruginosa or Haemophilus influenzae.
  • Treat urinary tract infections: Polyxx Injection helps eliminate gram-negative pathogens in complicated or hospital-acquired UTIs.
  • Address pulmonary infections: Polyxx Injection is used in cases of pneumonia and pulmonary embolism caused by multidrug-resistant gram-negative bacteria.

Key Benefits

Polyxx Injection belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. Polyxx Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Directions for Use

  • Polyxx Injection will be administered by a healthcare professional.
  • Do not self-administer it.

How Polyxx Injection Works

Polyxx Injection contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Polyxx Injection. Please consult the doctor.

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Pregnancy

Caution

The safety of polymyxin B in pregnancy has not been established. If you are pregnant or planning pregnancy, inform the doctor before receiving Polyxx Injection.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Polyxx Injection. Caution is advised while administering Polyxx Injection to lactating women.

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Driving

Consult your doctor

It is unknown if Polyxx Injection affects your ability to drive. Drive only if you are alert.

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Liver

Consult your doctor

If you have a history of liver problems, inform the doctor before receiving Polyxx Injection.

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Kidney

Caution

If you have a history of kidney problems, inform the doctor before receiving Polyxx Injection.

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Children

Safe if prescribed

Polyxx Injection may be safe for use in children if prescribed by the doctor.

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Heart

Caution

Polyxx Injection can be used in heart patients, but only with close medical supervision due to risks like kidney damage and neurotoxicity. Your doctor will assess your overall health and monitor you carefully throughout treatment.

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Geriatrics

Caution

Geriatric patients can receive Polyxx Injection, but with extra caution. Since kidney function often declines with age, doctors must monitor renal health closely and adjust the dosage accordingly.

What if I have taken an overdose of Polyxx Injection

As Polyxx Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Diet & Lifestyle Advise

  • Include whole grains, fruits, and vegetables in your diet. 
  • Taking probiotics after antibiotic treatment and eating high-fibre and prebiotic foods may help reduce side effects and support digestion.
  • Exercising regularly helps in improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress.
  • Avoid processed and fried food.

Have a query?

How Soon It Starts Working

The time required for Polyxx Injection to start to work: Polyxx Injection ideally shows its action within 2 hours after administration. The time for which the effects of Polyxx Injection last: The effect of Polyxx Injection lasts for 6 hours.

What if you forget to take Polyxx Injection

As this medicine is administered in a hospital by your healthcare professional, the chances of missing a dose are less. However, if you have any concerns, contact your doctor.

Storage

• Store in a cool and dry place away from sunlight. • Keep Polyxx Injection out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Do not receive Polyxx Injection if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. Seek medical attention if you experience symptoms of kidney problems (unable to pass urine, change in how much urine you pass), nerve problems (weakness, irritation, feeling sleepy, blurred eyesight, change in balance, numbness or tingling around the mouth or in the arms or legs, or trouble breathing), or Clostridium difficile associated diarrhoea/CDAD (stomach pain, cramps, very loose, watery, or bloody stool). Let the doctor know if you are taking any prescription/non-prescription medicines, including supplements or herbal products.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Inform the doctor if you are taking medicines that cause kidney or nerve problems.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform the doctor if you have kidney or nerve problems.

Polymyxin bAtracurium
Severe
Polymyxin bAdefovir dipivoxil
Severe

Drug-Drug Interactions

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Polymyxin bAtracurium
Severe
How does the drug interact with Polyxx Injection:
Co-administration of Polyxx Injection with Atracurium may cause serious breathing problems

How to manage the interaction:
There may be a possibility of interaction between Polyxx Injection and Atracurium, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without a doctor's advice.
Polymyxin bAdefovir dipivoxil
Severe
How does the drug interact with Polyxx Injection:
Taking Adefovir dipivoxil with Polyxx Injection may increase the risk of side effects.

How to manage the interaction:
Although taking Polyxx Injection and Adefovir dipivoxil together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, decreased hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bTobramycin
Severe
How does the drug interact with Polyxx Injection:
Taking Tobramycin with Polyxx Injection can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Tobramycin and Polyxx Injection, you can take these medicines together if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, difficulty breathing, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Polymyxin bSuxamethonium
Severe
How does the drug interact with Polyxx Injection:
Co-administration of Polyxx Injection may increase the effects of Suxamethonium when taken in combination.

How to manage the interaction:
Co-administration of Suxamethonium with Polyxx Injection can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
Polymyxin bVecuronium
Severe
How does the drug interact with Polyxx Injection:
Co-administration of Polyxx Injection and Vecuronium together may cause serious breathing problems.

How to manage the interaction:
Taking Polyxx Injection with Vecuronium together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any breathing difficulty, consult the doctor. Do not stop using any medications without a doctor's advice.
Polymyxin bStreptomycin
Severe
How does the drug interact with Polyxx Injection:
Using Polyxx Injection together with streptomycin can increase the risk or severity of developing hearing loss, breathing problems, and kidney problems.

How to manage the interaction:
Although taking Polyxx Injection and Streptomycin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medication without consulting a doctor.
Polymyxin bTenofovir alafenamide
Severe
How does the drug interact with Polyxx Injection:
Taking Tenofovir alafenamide with Polyxx Injection can increase the chance of side effects.

How to manage the interaction:
Taking Tenofovir alafenamide with Polyxx Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bCidofovir
Severe
How does the drug interact with Polyxx Injection:
Taking Cidofovir with Polyxx Injection sulfate can increase the risk of kidney problems.

How to manage the interaction:
Although taking Polymyxin-b and Cidofovir together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, swelling, breathing difficulty, bone pain, muscle pain, dizziness, confusion, or irregular heart rhythm, consult a doctor. Do not stop using any medications without talking to a doctor.
Polymyxin bKanamycin
Severe
How does the drug interact with Polyxx Injection:
Taking Kanamycin with Polyxx Injection can increase the risk and severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Polyxx Injection and Kanamycin, but it can be taken if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, vertigo, difficulty breathing, nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bBCG vaccine
Severe
How does the drug interact with Polyxx Injection:
When the BCG vaccine is used with Polyxx Injection, its effectiveness may be reduced.

How to manage the interaction:
There may be a possibility of interaction between Polyxx Injection and BCG vaccine, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Polyxx Injection is used to treat Bacterial infections.

Polyxx Injection works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Diarrhoea might be a side effect of Polyxx Injection. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult the doctor if the condition persists or worsens.

Polyxx Injection may cause nerve problems. Consult the doctor if you experience weakness, irritation, change in balance, feeling sleepy, blurred eyesight, trouble breathing, numbness or tingling sensation in the arms and legs.

Polyxx Injection will be administered by a healthcare professional. Do not self-administer.

Yes, Polyxx Injection is safe when used only under the doctor’s supervision. However, it may cause pain at the injection site, flushing, dizziness, and diarrhoea while using it.

The common side effects of Polyxx Injection may include pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Other Info - POL0442

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