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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Polypure 500000Iu Inj is used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. It contains Polymyxin B, which destroys bacterial cell membranes and kills infection-causing bacteria. Thereby, it helps treat bacterial infections. In some cases, Polypure 500000Iu Inj may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea.

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Synonym :

POLYMYXIN B SULPHATE

Manufacturer/Marketer :

Alniche Life Sciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Polypure 500000Iu Inj

Polypure 500000Iu Inj belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms.

Polypure 500000Iu Inj contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

In some cases, Polypure 500000Iu Inj may cause side effects such as pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Let the doctor know if you are allergic to any of the components in Polypure 500000Iu Inj. Consult the doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Polypure 500000Iu Inj

Polypure 500000Iu Inj is used in the treatment of Bacterial infections. The detailed uses of Polypure 500000Iu Inj are as follows:

  • Treat bloodstream infections: Polypure 500000Iu Inj is effective against septicemia caused by resistant gram-negative bacteria such as Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli.
  • Manage meningitis: Polypure 500000Iu Inj is administered intrathecally to treat bacterial meningitis, especially when caused by Pseudomonas aeruginosa or Haemophilus influenzae.
  • Treat urinary tract infections: Polypure 500000Iu Inj helps eliminate gram-negative pathogens in complicated or hospital-acquired UTIs.
  • Address pulmonary infections: Polypure 500000Iu Inj is used in cases of pneumonia and pulmonary embolism caused by multidrug-resistant gram-negative bacteria.

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Directions for Use

  • Polypure 500000Iu Inj will be administered by a healthcare professional.
  • Do not self-administer it.

Medicinal Benefits

Polypure 500000Iu Inj belongs to the group of medicines called antibiotics used to treat bacterial infections such as urinary tract infections, meningitis, bloodstream infections, and corneal and subconjunctival eye infections caused by susceptible organisms. Polypure 500000Iu Inj contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

How Polypure 500000Iu Inj Works

Polypure 500000Iu Inj contains Polymyxin B, which works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Storage

• Store in a cool and dry place away from sunlight.• Keep Polypure 500000Iu Inj out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Polypure 500000Iu Inj

As Polypure 500000Iu Inj is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Do not receive Polypure 500000Iu Inj if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. Seek medical attention if you experience symptoms of kidney problems (unable to pass urine, change in how much urine you pass), nerve problems (weakness, irritation, feeling sleepy, blurred eyesight, change in balance, numbness or tingling around the mouth or in the arms or legs, or trouble breathing), or Clostridium difficile associated diarrhoea/CDAD (stomach pain, cramps, very loose, watery, or bloody stool). Let the doctor know if you are taking any prescription/non-prescription medicines, including supplements or herbal products.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Polypure 500000Iu Inj:
Co-administration of Sirolimus and Polypure 500000Iu Inj together may increase the risk or severity of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Sirolimus and Polypure 500000Iu Inj, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Polypure 500000Iu Inj:
Taking Human immunoglobulin with Polymyxin- b, may raise the risk of kidney problems.

How to manage the interaction:
Although taking Human immunoglobulin and Polypure 500000Iu Inj together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Polypure 500000Iu Inj:
Co-administration of Netilmicin with Polypure 500000Iu Inj can increase the risk of side effects.

How to manage the interaction:
Co-administration of Netilmicin with Polypure 500000Iu Inj can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Polypure 500000Iu Inj:
Using Polypure 500000Iu Inj together with streptomycin can increase the risk or severity of developing hearing loss, breathing problems, and kidney problems.

How to manage the interaction:
Although taking Polypure 500000Iu Inj and Streptomycin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Polypure 500000Iu Inj:
Coadministration of Tenofovir disoproxil with Polypure 500000Iu Inj can increase the risk of side effects.

How to manage the interaction:
Taking Tenofovir disoproxil with Polypure 500000Iu Inj together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor immediately. Do not stop using any medications without consulting a doctor.
Polymyxin bIodamide
Severe
How does the drug interact with Polypure 500000Iu Inj:
Co-administration of Iodamide with Polypure 500000Iu Inj may increase the risk of kidney damage.

How to manage the interaction:
Although there is a possible interaction between Polypure 500000Iu Inj and Iodamide, you can take these medicines together if prescribed by a doctor. However, contact a doctor immediately if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, muscle pain, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Polypure 500000Iu Inj:
Co-administration of Deferasirox and Polypure 500000Iu Inj may increase the risk of kidney problems.

How to manage the interaction:
Although taking Polypure 500000Iu Inj and Deferasirox together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, swelling, breathing difficulty, bone pain, muscle pain, dizziness, confusion, or irregular heart rhythm, seek immediate medical attention. Drink plenty of water if you experience diarrhea or vomiting while taking these medications, as dehydration can potentially affect the kidneys. Do not discontinue any medications without a doctor's advice.
Polymyxin bBCG vaccine
Severe
How does the drug interact with Polypure 500000Iu Inj:
When the BCG vaccine is used with Polypure 500000Iu Inj, its effectiveness may be reduced.

How to manage the interaction:
There may be a possibility of interaction between Polypure 500000Iu Inj and BCG vaccine, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Polypure 500000Iu Inj:
Taking Tobramycin with Polypure 500000Iu Inj can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Tobramycin and Polypure 500000Iu Inj, you can take these medicines together if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, difficulty breathing, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Polypure 500000Iu Inj:
Taking Polypure 500000Iu Inj with Pancuronium together can cause breathing problems.

How to manage the interaction:
Taking Polypure 500000Iu Inj with Pancuronium together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any breathing problems, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include whole grains, fruits, and vegetables in your diet. 
  • Taking probiotics after antibiotic treatment and eating high-fibre and prebiotic foods may help reduce side effects and support digestion.
  • Exercising regularly helps in improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress.
  • Avoid processed and fried food.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Polypure 500000Iu Inj. Please consult the doctor.

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Pregnancy

Caution

The safety of polymyxin B in pregnancy has not been established. If you are pregnant or planning pregnancy, inform the doctor before receiving Polypure 500000Iu Inj.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Polypure 500000Iu Inj. Caution is advised while administering Polypure 500000Iu Inj to lactating women.

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Driving

Consult your doctor

It is unknown if Polypure 500000Iu Inj affects your ability to drive. Drive only if you are alert.

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Liver

Consult your doctor

If you have a history of liver problems, inform the doctor before receiving Polypure 500000Iu Inj.

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Kidney

Caution

If you have a history of kidney problems, inform the doctor before receiving Polypure 500000Iu Inj.

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Children

Safe if prescribed

Polypure 500000Iu Inj may be safe for use in children if prescribed by the doctor.

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Heart

Polypure 500000Iu Inj can be used in heart patients, but only with close medical supervision due to risks like kidney damage and neurotoxicity. Your doctor will assess your overall health and monitor you carefully throughout treatment.

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Geriatrics

Caution

Geriatric patients can receive Polypure 500000Iu Inj, but with extra caution. Since kidney function often declines with age, doctors must monitor renal health closely and adjust the dosage accordingly.

FAQs

Polypure 500000Iu Inj is used to treat Bacterial infections.

Polypure 500000Iu Inj works by destroying bacterial cell membranes and killing infection-causing bacteria. Thereby, it helps treat bacterial infections.

Diarrhoea might be a side effect of Polypure 500000Iu Inj. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult the doctor if the condition persists or worsens.

Polypure 500000Iu Inj may cause nerve problems. Consult the doctor if you experience weakness, irritation, change in balance, feeling sleepy, blurred eyesight, trouble breathing, numbness or tingling sensation in the arms and legs.

Polypure 500000Iu Inj will be administered by a healthcare professional. Do not self-administer.

Yes, Polypure 500000Iu Inj is safe when used only under the doctor’s supervision. However, it may cause pain at the injection site, flushing, dizziness, and diarrhoea while using it.

The common side effects of Polypure 500000Iu Inj may include pain at the injection site, flushing, dizziness, and diarrhoea. Most of these side effects may not require medical attention and resolve gradually over time. However, consult a doctor if the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Alniche Life Sciences Pvt. Ltd., S-14, 2nd Floor, Janta Market Rajouri Garden, New Delhi – 110 027
Other Info - POL0363

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