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PIROX CAPSULE 20MG is used to relieve symptoms like pain, inflammation, and joint stiffness associated with rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It contains Piroxicam, which stops the production of prostaglandins (chemicals) that are produced at injury sites and cause pain and swelling. In some cases, you may experience common side effects, such as diarrhoea, stomach upset, headache, dizziness, ringing in the ears, heartburn, nausea, vomiting, and constipation. Before taking this medicine, inform your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

PIROXICAM-20MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About PIROX CAPSULE 20MG

PIROX CAPSULE 20MG is a prescription medication used to reduce pain, swelling, and joint stiffness caused by arthritis. It belongs to a group of medicines that target inflammation directly to help you maintain your daily mobility. It is primarily prescribed to manage chronic, long-term joint symptoms.

For the best results, take PIROX CAPSULE 20MG consistently at the same time every day. It is highly recommended to take this medicine with food or a glass of milk to protect your stomach from irritation. Incorporating low-impact physical exercise and managing your weight can also help improve your joint health.

While PIROX CAPSULE 20MG is effective, it can cause mild side effects like an upset stomach, nausea, or headaches. You must contact your doctor immediately if you experience serious symptoms like severe stomach pain, black stools, or sudden shortness of breath.

Talk to your doctor before starting PIROX CAPSULE 20MG if you have a history of stomach ulcers, heart disease, high blood pressure, or kidney issues. Do not take this medicine if you are allergic to aspirin or similar pain relievers, or if you recently had heart bypass surgery.

PIROX CAPSULE 20MG can interact with blood thinners, other pain relievers, and alcohol, increasing the risk of stomach bleeding. If you are pregnant, breastfeeding, or over 65, talk to your doctor or pharmacist before taking this medicine to ensure it is safe for you.

Uses of PIROX CAPSULE 20MG

Below are some of the common conditions for which PIROX CAPSULE 20MG may be prescribed: 

  • Osteoarthritis: PIROX CAPSULE 20MG helps reduce painful joint swelling, stiffness, and tenderness, allowing for easier movement and improved daily physical function.
  • Rheumatoid Arthritis: It targets chronic joint inflammation, helping to ease morning stiffness and relieve ongoing joint pain.
  • Ankylosing Spondylitis: This medicine reduces inflammation and stiffness in the spine, helping you maintain flexibility and posture.

Key Benefits

Using PIROX CAPSULE 20MG can provide several practical benefits that help you manage chronic joint pain and improve your physical comfort:

  • Long-lasting pain relief: Because this medicine stays active in your body for a long time, it provides steady, round-the-clock relief from chronic pain with just a single daily dose.
  • Improved joint mobility: By reducing swelling and morning stiffness in your joints, it makes daily activities like walking, climbing stairs, and bending much easier.
  • Reduced joint inflammation: It directly targets the inflammatory processes that cause discomfort, helping to protect your joints from ongoing strain.
Side effects of Pirox Capsule 20mg
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.

Directions for Use

To ensure you take PIROX CAPSULE 20MG safely and effectively, follow these step-by-step instructions:

  • Swallow the capsule or tablet whole with a full glass of water. Do not crush, chew, or break it.
  • Take this medication with food, a meal, or a glass of milk to reduce the risk of stomach upset.
  • Take your dose at the same time every day to maintain a consistent level of medicine in your body.
  • Always follow your doctor's exact instructions regarding your dose. Talk to your doctor or pharmacist if you have any questions about how to take this medicine.

How PIROX CAPSULE 20MG Works

PIROX CAPSULE 20MG belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). When your joints are inflamed, your body produces chemical messengers called prostaglandins. These chemicals are directly responsible for causing pain, swelling, and redness in the affected areas. This medication works by blocking the specific enzymes that produce these prostaglandins. By stopping the production of these chemicals, PIROX CAPSULE 20MG effectively calms inflammation at its source. This reduction in swelling and chemical activity leads to significantly less pain and stiffness in your joints, allowing you to move more freely and comfortably.
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Alcohol

Unsafe

Avoid alcohol consumption while taking PIROX CAPSULE 20MG, as it may cause increased dizziness and drowsiness. It may also cause an increase in the risk of stomach/intestinal ulcers and bleeding.

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Pregnancy

Caution

Avoid taking PIROX CAPSULE 20MG if you are pregnant unless prescribed by the doctor. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe PIROX CAPSULE 20MG only if the benefits outweigh the risks. Do not take PIROX CAPSULE 20MG in the last 20 weeks of pregnancy, as it may cause serious kidney and heart problems in the unborn baby and complications with the pregnancy.

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Breast Feeding

Unsafe

PIROX CAPSULE 20MG can pass into breast milk. So, avoid breastfeeding while taking PIROX CAPSULE 20MG. Please consult your doctor if you have any concerns regarding this.

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Driving

Unsafe

PIROX CAPSULE 20MG may cause drowsiness, dizziness, and vision problems. Do not drive or operate heavy machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. PIROX CAPSULE 20MG should be used with caution in patients with liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. PIROX CAPSULE 20MG should be used with caution in patients with kidney impairment/kidney disease.

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Children

Unsafe

PIROX CAPSULE 20MG is not recommended for children under 18 years, as its efficacy and safety have not been established.

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Heart

Caution

PIROX CAPSULE 20MG may increase the risk of heart attack or stroke. Do not use PIROX CAPSULE 20MG immediately before or after bypass surgery. Inform your doctor if you have a history of heart disease or other heart problems.

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Geriatrics

Caution

PIROX CAPSULE 20MG may be used in geriatric patients, but only with caution and close medical supervision due to its long half-life and increased risk of serious side effects.

What if I have taken an overdose of PIROX CAPSULE 20MG

If you suspect an overdose, seek immediate medical attention or contact your local emergency services right away. Signs of an overdose can include severe drowsiness, nausea, vomiting, stomach pain, or difficulty breathing.

Diet & Lifestyle Advise

  • Avoid alcohol and tobacco: Both of these substances can irritate your stomach lining and significantly increase your risk of developing stomach ulcers or bleeding while taking PIROX CAPSULE 20MG.
  • Stay well-hydrated: Drink plenty of water throughout the day to help your kidneys flush out the medication safely and prevent kidney strain.
  • Eat an anti-inflammatory diet: Focus on foods rich in omega-3 fatty acids (like salmon or flaxseeds), berries, and leafy green vegetables to help naturally manage joint inflammation.
  • Engage in low-impact exercise: Activities like swimming, cycling, or walking keep your joints flexible and strengthen the surrounding muscles without putting too much pressure on them.
  • Manage your weight: Maintaining a healthy weight reduces the physical stress and load placed on your weight-bearing joints, such as your knees and hips.
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Have a query?

How Soon It Starts Working

  • The time required for PIROX CAPSULE 20MG to start to work: The time required for PIROX CAPSULE 20MG to show its action is unknown.
  • The time for which the effects of PIROX CAPSULE 20MG last: The effect of PIROX CAPSULE 20MG lasts for 11 to 12 days.

What if you forget to take PIROX CAPSULE 20MG

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is less than 12 hours away, skip the missed dose entirely and return to your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

• Store PIROX CAPSULE 20MG at room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the medicine in its original container to protect it from moisture and direct light.

Drug Warnings

  • Monitor your blood pressure: PIROX CAPSULE 20MG can cause your blood pressure to rise, so it is important to check it regularly while taking this medication.
  • Watch for signs of bleeding: Check your stool for dark, tarry colors and contact your doctor immediately if you notice any changes.
  • Avoid other NSAIDs: Do not take over-the-counter pain relievers like ibuprofen or naproxen alongside PIROX CAPSULE 20MG, as this greatly increases your risk of severe stomach ulcers.
  • Protect your skin from the sun: This medicine can make your skin more sensitive to sunlight. Wear protective clothing and apply sunscreen when outdoors.
  • Inform your surgical team: If you are planning to have any dental work or surgery, tell your dentist or surgeon that you are taking PIROX CAPSULE 20MG, as it may affect blood clotting.
  • Have regular blood tests: If you take this medicine long-term, your doctor may recommend routine blood tests to check your kidney and liver health.

Drug-Drug Interactions

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The following medicines may interact with PIROX CAPSULE 20MG and affect its safety or effectiveness: 

  • Blood thinners: Combining these with PIROX CAPSULE 20MG can significantly increase your risk of serious stomach and internal bleeding.
  • Other NSAIDs: Taking these together increases the risk of severe stomach irritation, ulcers, and kidney strain.
  • Blood pressure medicines: PIROX CAPSULE 20MG can make these medications less effective at lowering your blood pressure and may increase the strain on your kidneys.
  • Lithium: This medicine can raise lithium levels in your blood to unsafe limits, increasing the risk of toxicity.

Drug-Drug Interactions

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How does the drug interact with Pirox Capsule 20mg:
Using ketorolac tromethamine together with Pirox Capsule 20mg may increase the risk of side effects.

How to manage the interaction:
Taking Pirox Capsule 20mg with Ketorolac tromethamine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pirox Capsule 20mg:
Co-administration of Cidofovir with Pirox Capsule 20mg can increase the risk of kidney problems.

How to manage the interaction:
Taking Pirox Capsule 20mg with Cidofovir is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pirox Capsule 20mg:
Coadministration of Warfarin with Pirox Capsule 20mg can increase the risk of bleeding.

How to manage the interaction:
Although taking Pirox Capsule 20mg with Warfarin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness consult a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Pirox Capsule 20mg:
Using perindopril together with Pirox Capsule 20mg may reduce the effects of perindopril in lowering blood pressure, they may also increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Pirox Capsule 20mg with Perindopril can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, muscle pain, and irregular heart rhythm, contact a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Pirox Capsule 20mg:
Coadministration of Pirox Capsule 20mg and Leflunomide can increase the risk of liver damage.

How to manage the interaction:
Although there is a possible interaction between Leflunomide and Pirox Capsule 20mg, you can take these medicines together if prescribed by a doctor. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of hunger, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pirox Capsule 20mg:
Using Dasatinib together with Pirox Capsule 20mg may increase the risk of bleeding.

How to manage the interaction:
Taking Pirox Capsule 20mg with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. If you experience bruising, feeling dizzy or lightheaded, dark or bloody stools, headaches, contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pirox Capsule 20mg:
Co-administration of Pirox Capsule 20mg and Ibrutinib can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Pirox Capsule 20mg and Ibrutinib, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pirox Capsule 20mg:
Coadministration of celecoxib with Pirox Capsule 20mg can increase the risk and severity of gastrointestinal toxicity.

How to manage the interaction:
Although there is a interaction between Pirox Capsule 20mg and Celecoxib, but it can be taken if your doctor has advised it. However, consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Pirox Capsule 20mg:
Coadministration of Pirox Capsule 20mg with Adefovir dipivoxil can increase the risk of kidney problems.

How to manage the interaction:
Taking Pirox Capsule 20mg with Adefovir dipivoxil together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pirox Capsule 20mg:
Using Pirox Capsule 20mg together with flurbiprofen may increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding and ulceration.

How to manage the interaction:
Although there is a possible interaction between Flurbiprofen and Pirox Capsule 20mg, it can be taken if your doctor has advised it. However, if you experience dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

Certain foods and beverages may increase the risk of side effects while taking PIROX CAPSULE 20MG: 

  • Alcohol: Drinking alcohol while taking this medicine severely increases your risk of developing stomach ulcers or gastrointestinal bleeding.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

PIROX CAPSULE 20MG is used to relieve symptoms like pain, inflammation, and joint stiffness associated with rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
PIROX CAPSULE 20MG works by blocking the effect of chemical messengers (prostaglandin), thereby reducing joint pain, stiffness, swelling, and inflammation.
Diarrhoea might be a side effect of PIROX CAPSULE 20MG. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
PIROX CAPSULE 20MG may increase the risk of heart attack or stroke. Do not use PIROX CAPSULE 20MG within 1 week before or after bypass surgery. Inform your doctor if you have a history of heart disease or other heart problems.
Consult your doctor before taking PIROX CAPSULE 20MG if you have diabetes, as PIROX CAPSULE 20MG might increase your blood sugar levels.
The common side effects of PIROX CAPSULE 20MG are diarrhoea, stomach upset, headache, dizziness, ringing in the ears, heartburn, nausea, vomiting, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to speak to your doctor if you experience these side effects persistently.
You may feel some pain relief within the first few days of starting PIROX CAPSULE 20MG. However, for chronic conditions like arthritis, it can take up to two weeks of consistent daily use to experience the full anti-inflammatory benefits. Talk to your doctor if you do not feel any improvement after two weeks.
It is highly recommended that you do not take PIROX CAPSULE 20MG on an empty stomach. Taking this medication with food, a meal, or a glass of milk helps protect your stomach lining and reduces the risk of common side effects like nausea or indigestion. Talk to your doctor or pharmacist if you continue to experience stomach discomfort.
You should avoid taking PIROX CAPSULE 20MG during pregnancy, especially during the last three months, as it can cause serious complications for the unborn baby and affect labor. Always consult your doctor before taking any medication if you are pregnant or planning to become pregnant.
While sleepiness is not a highly common side effect of PIROX CAPSULE 20MG, some patients may experience dizziness, drowsiness, or lightheadedness. If you feel dizzy or sleepy after taking this medicine, avoid driving, operating heavy machinery, or performing tasks that require full alertness. Talk to your doctor if these symptoms persist.
Yes, in most cases, you can take paracetamol occasionally for additional pain relief while taking PIROX CAPSULE 20MG, as they work differently in the body. However, you must avoid taking other NSAIDs like ibuprofen or naproxen. Always talk to your doctor or pharmacist before combining any pain medications.
The duration of your treatment depends entirely on your specific medical condition and how well you tolerate the medicine. Because long-term use of NSAIDs can increase the risk of stomach and heart problems, your doctor will prescribe the lowest effective dose for the shortest time possible. Talk to your doctor regularly to review your treatment plan.
Yes, PIROX CAPSULE 20MG can cause fluid retention, which can lead to an increase in blood pressure. If you already have high blood pressure or heart disease, your doctor will monitor you closely while you are taking this medication. Talk to your doctor if you notice an unusual rise in your blood pressure readings.
If you develop severe stomach pain, heartburn, or notice black, tarry stools, stop taking PIROX CAPSULE 20MG immediately and seek urgent medical help. These can be warning signs of serious stomach irritation or bleeding. Talk to your doctor right away if you experience any unusual digestive symptoms.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - PIR0012
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