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Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Perigard D Tablet

Perigard D Tablet is used to treat high blood pressure. Hypertension (High blood pressure) is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Perigard D Tablet contains Perindopril and Indapamide. Perindopril works by relaxing the blood vessels and improving blood flow. Indapamide increases the amount of urine passed out from the kidneys. Together, Perigard D Tablet helps treat hypertension.

Sometimes, you may experience headaches, tiredness, a slow heart rate, and nausea. Most of these side effects of Perigard D Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take Perigard D Tablet if you are allergic to any of its components. Tell your doctor if you have had or currently have liver, kidney, or heart problems. In pregnancy and lactation, Perigard D Tablet should only be taken after consulting your doctor.

Uses of Perigard D Tablet

Perigard D Tablet used in the treatment of Hypertension (high blood pressure). The detailed uses of Perigard D Tablet are as follows:

  • Management of Hypertension: Perigard D Tablet helps to lower high blood pressure by relaxing the blood vessels and increasing urine production.
  • Reducing Cardiovascular Risk: Perigard D Tablet reduces the risk of cardiovascular complications such as heart attack or stroke associated with high blood pressure.

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Directions for Use

  • Perigard D Tablet can be taken before a meal, preferably in the morning or as advised by your doctor.
  • It should be taken once a day or as directed by the doctor.
  • Swallow Perigard D Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

Medicinal Benefits

  • Perigard D Tablet contains Perindopril and Indapamide, which help manage hypertension and maintain healthy blood pressure levels.
  • By controlling blood pressure, Perigard D Tablet lowers the chances of cardiovascular complications such as heart attack, stroke, or heart failure.
  • Perindopril, an ACE inhibitor, relaxes and widens blood vessels by blocking angiotensin II, improving blood flow and reducing strain on the heart.
  • It allows the heart to pump blood more efficiently, enhancing overall heart function.
  • Indapamide helps eliminate excess salt and water from the body without causing excessive urination, aiding in blood pressure control.
  • By promoting balanced fluid removal, Perigard D Tablet helps prevent swelling (oedema) and maintains electrolyte stability.
  • Perigard D Tablet supports cardiovascular and renal health by preventing damage caused by persistent high blood pressure.

How Perigard D Tablet Works

Perigard D Tablet contains two medicines: Perindopril (blood pressure-lowering agent) and Indapamide (diuretic or water pill). Perindopril is an angiotensin-converting enzyme or ACE inhibitor that lowers high blood pressure by blocking a naturally occurring substance known as angiotensin II (which tightens your blood vessels). It allows these constricted blood vessels to relax and helps lower high blood pressure. On the other hand, Indapamide (diuretic) increases the amount of urine passed out from the kidneys. But unlike other water pills, it does not increase urine output and effectively reduces excess fluid overload in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both can lower high blood pressure, reducing the chances of a heart attack or stroke.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Perigard D Tablet

Do not take more than the prescribed dose of Perigard D Tablet as it may cause an overdose. The symptoms of overdose include cramps, dizziness, nausea, vomiting, mental confusion, or a change in the amount of urine. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Perigard D Tablet if you are allergic to any of its components.
  • Inform your doctor if you have had a heart attack, kidney disease, liver disease, are pregnant, planning to get pregnant or breastfeeding.
  • Perigard D Tablet is not recommended in neonates and children.
  • Do not take Perigard D Tablet with alcohol as it may cause low blood pressure (hypotension) with symptoms of dizziness, drowsiness, weariness, or sleepiness.
  • Tell your doctor you are using Perigard D Tablet before undergoing dental or other surgery. Your doctor might stop this medicine before the surgery.
  • Perigard D Tablet contains Indapamide, which positively reacts to drug tests, so if you are an athlete, be aware that if you are taking Perigard D Tablet and are undergoing a drug test.
  • Let your doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Perigard D Tablet:
Combining Aliskiren with Perigard D Tablet can increase the risk of low blood pressure, high potassium levels, and kidney damage.

How to manage the interaction:
Taking Perigard D Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Perigard D Tablet:
Taking Perigard D Tablet with Thioridazine can increase the risk of heart problems.

How to manage the interaction:
Taking Thioridazine with Perigard D Tablet is not recommended, but can be taken if prescribed by the doctor.
IndapamideProtriptyline
Critical
How does the drug interact with Perigard D Tablet:
Taking Protriptyline along with Perigard D Tablet can lead to serious heart problems.

How to manage the interaction:
Taking Protriptyline with Perigard D Tablet is not recommended, but can be taken if prescribed by the doctor.
IndapamideDroperidol
Critical
How does the drug interact with Perigard D Tablet:
Taking Droperidol with Perigard D Tablet can lead to severe heart problems.

How to manage the interaction:
Taking Droperidol with Perigard D Tablet is not recommended, but can be taken if prescribed by the doctor.
How does the drug interact with Perigard D Tablet:
Co-administration of Allopurinol with Perigard D Tablet may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Allopurinol and Perigard D Tablet, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms, contact your doctor immediately . Do not discontinue any medications without consulting a doctor.
PerindoprilPotassium hydrogencarbonate
Severe
How does the drug interact with Perigard D Tablet:
Using Perigard D Tablet together with potassium hydrogencarbonate may significantly increase potassium levels in the blood.

How to manage the interaction:
Co-administration of Perigard D Tablet with Potassium hydrogencarbonate can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not stop using any medications without a doctor's advice. Do not discontinue any medications without first consulting your doctor.
PerindoprilPotassium iodide
Severe
How does the drug interact with Perigard D Tablet:
Combining Potassium Iodide with Perigard D Tablet can cause hyperkalemia(high potassium levels in blood) which can increase the risk the risk of kidney problems and abnormal heart rhythm.

How to manage the interaction:
Taking Perigard D Tablet with Potassium iodide together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not stop using any medications without a doctor's advice. Do not discontinue any medications without consulting your doctor.
PerindoprilMipomersen
Severe
How does the drug interact with Perigard D Tablet:
Using Perigard D Tablet together with mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Perigard D Tablet with Mipomersen can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Perigard D Tablet:
Taking Perigard D Tablet with telmisartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and high blood potassium.

How to manage the interaction:
Although there is a possible interaction, telmisartan can be taken with Perigard D Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms of high potassium such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Maintain adequate fluid intake during treatment with these medications. Do not discontinue the medications without consulting a doctor.
PerindoprilTriamterene
Severe
How does the drug interact with Perigard D Tablet:
Combining Triamterene with Perigard D Tablet can increase the risk of hyperkalemia.

How to manage the interaction:
Although taking Perigard D Tablet and Triamterene together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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INDAPAMIDE-1.25MG+PERINDOPRIL-4MGPotassium rich foods
Moderate

Drug-Food Interactions

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INDAPAMIDE-1.25MG+PERINDOPRIL-4MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Tomatoes, Sweet Potatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consuming Potassium containing food with Perindopril and Indapamide can increase the risk of high levels of potassium in your blood. Avoid consuming Potassium-containing food with Perindopril and Indapamide.

Diet & Lifestyle Advise

  • Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Be mindful of salt; consume no more than 2,300 mg each day.
  • Limit or avoid alcohol consumption.
  • Quitting smoking is the best strategy to lower the risk of heart disease.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES
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Alcohol

Unsafe

Limit or cut down alcohol consumption; alcohol consumption may enhance this drug's hypotensive (low blood pressure) effect

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Pregnancy

Caution

The use of Perigard D Tablet or any ACE inhibitors (pregnancy category D) is usually contraindicated during the second and third trimesters of pregnancy. It may cause harm to the developing fetus. Hence, you should always consult your doctor before using Perigard D Tablet .

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Breast Feeding

Caution

Use of Perigard D Tablet is not recommended during the breastfeeding stage.

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Driving

Caution

Drive with caution, Perigard D Tablet may cause blurry vision, and dizziness or weariness may occur.

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Liver

Caution

Perigard D Tablet to be taken with caution, especially in case of severe liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Perigard D Tablet to be taken with caution, especially in case of severe kidney disease. The dose may have to be adjusted by your doctor. Perigard D Tablet should be given with precaution in hemodialysis conditions.

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Children

Caution

Perigard D Tablet is not recommended for children. The safety and effectiveness of Perigard D Tablet have not been established in children due to limited testing of this drug on children by competent authorities worldwide. If necessary, your doctor will decide whether to give Perigard D Tablet or not.

FAQs

Perigard D Tablet is used to treat hypertension (high blood pressure), a condition in which the blood exerts increased pressure on the walls of blood vessels.

Perigard D Tablet contains two medicines: Perindopril (blood pressure-lowering agent) and Indapamide (diuretic or water pill). Perindopril is an angiotensin-converting enzyme or ACE inhibitor that lowers high blood pressure by blocking a naturally occurring substance known as angiotensin II (which tightens your blood vessels). Indapamide (diuretic) increases the amount of urine passed out from the kidneys. Thus, both help lower high blood pressure, reducing the chances of a heart attack or stroke.

It is advised to continue your medicine even after your blood pressure is under control or becomes normal, as blood pressure can shoot up at any time. If you have any discomfort, please consult your doctor immediately.

Usually, Perigard D Tablet is prescribed for a long-term treatment ranging from months to years for treating heart-related conditions and disorders. However, taking it on your own for years without a doctor's consent can be fatal. Hence, only take it as long as your doctor prescribes it.

Before surgery, you should inform your doctor that you are taking Perigard D Tablet to reduce your blood pressure when used along with anaesthesia, which is given before a major operation.

Perigard D Tablet contains Indapamide, which gives a positive reaction to drug tests. If you are an athlete, be aware if you are taking Perigard D Tablet and are undergoing a drug test.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai €“ 400 026.
Other Info - PER0013

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