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Paraxin Suspension 60 ml is used to treat bacterial infections. It contains Chloramphenicol which works by killing the infection-causing bacteria. In some cases, this medicine may cause side effects such as nausea, vomiting, diarrhoea, and headache. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Paraxin Suspension 60 ml

Paraxin Suspension 60 ml is a suspension prescribed to treat serious bacterial infections, such as typhoid fever and severe forms of meningitis, when other safer antibiotics cannot be used. It works by stopping the growth of bacteria, helping your body overcome severe illnesses. This medicine is reserved for critical infections due to its potential for serious side effects. 

To ensure this medication works effectively, you must take it consistently at evenly spaced intervals as directed by your healthcare provider. It is best taken on an empty stomach, either 1 hour before or 2 hours after meals, with a full glass of water. If you experience stomach upset, your doctor may suggest taking it with a small amount of food. Staying well-hydrated and getting plenty of rest are helpful lifestyle adjustments to support your recovery during treatment.

While taking Paraxin Suspension 60 ml, you may experience mild, common side effects like nausea, vomiting, or diarrhoea. However, you must contact your doctor immediately if you experience signs of serious side effects, such as unusual bruising, extreme fatigue, pale skin, sore throat, or a sudden fever. These can be early warning signs of severe blood disorders.

Do not take this if you have a history of allergic reactions to this medication or if you have previously suffered from blood disorders like anaemia or bone marrow suppression. It is also important to tell your doctor before taking this medicine if you have liver damage, kidney disease, or a genetic condition called G6PD deficiency. This medicine should not be given to newborns and neonates because their immature liver function can increase the risk of a life-threatening reaction known as 'grey baby syndrome.' Use in older infants, if considered necessary, should only occur under close specialist supervision.

This medicine can interact with blood thinners, certain seizure medications, and other antibiotics, which can change how these drugs work or increase your risk of side effects. Avoid drinking alcohol while taking this medicine, as it can cause unpleasant interactions like nausea and headaches. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly patient, consult your doctor before starting this medicine, as specialised precautions or alternative treatments may be necessary.

Uses of Paraxin Suspension 60 ml

Paraxin Suspension 60 ml may be used in the following situations:

  • Typhoid and paratyphoid fever: Paraxin Suspension 60 ml helps by stopping the growth of the specific bacteria causing these severe, systemic infections.
  • Bacterial meningitis: It penetrates brain tissues effectively to treat severe infections of the protective membranes surrounding the brain and spinal cord.
  • Severe rickettsial infections: It treats life-threatening infections, such as Rocky Mountain spotted fever, when first-line antibiotics are not an option.
  • Serious Haemophilus influenzae infections: It targets and eliminates these difficult-to-treat respiratory or systemic bacterial infections.

Key Benefits

Paraxin Suspension 60 ml is an antibiotic used to treat certain serious bacterial infections when other, safer antibiotics are not suitable. It works by inhibiting bacterial protein synthesis, preventing susceptible bacteria from growing and multiplying.

  • Treats Serious Bacterial Infections: Helps treat certain severe infections caused by susceptible bacteria when alternative antibiotics are ineffective or inappropriate.
    Helps Control Infection: By stopping bacterial growth, it allows the body's immune system to help clear the infection.
  • Reaches Infected Tissues: Chloramphenicol is well absorbed after oral administration and distributes widely throughout the body, allowing it to reach tissues where susceptible bacterial infections may occur.
  • Supports Recovery: Effective treatment of the underlying bacterial infection may help reduce symptoms such as fever, pain, and general weakness as the infection improves.

Directions for Use

  • Paraxin Suspension 60 ml can be taken 1 hour before or 2 hours after a meal.
  • It is recommended to take 2-3 times a day or as advised by your doctor.
  • Shake the bottle well before use.
  • Measure the prescribed dose using the measuring cup provided with the pack and administer it orally.

How Paraxin Suspension 60 ml Works

Paraxin Suspension 60 ml contains chloramphenicol. It belongs to a group of medicines known as bacteriostatic antibiotics. Once swallowed, the medicine enters the bacterial cells and binds to their protein-producing machinery. By preventing the bacteria from making essential proteins, it stops their ability to grow, repair, and multiply. Without the ability to replicate, the existing bacteria are eventually cleared away by your body's natural immune system.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Paraxin Suspension 60 ml. Please consult a doctor if you have concerns.

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Pregnancy

Unsafe

Do not take Paraxin Suspension 60 ml if you are pregnant, as it may harm your foetus. Please consult your doctor if you have any concerns.

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Breast Feeding

Unsafe

Do not take Paraxin Suspension 60 ml if you are breastfeeding as it may pass into breast milk and harm your infant. Please consult your doctor if you have any concerns.

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Driving

Safe if prescribed

Paraxin Suspension 60 ml does not affect your ability to drive. However, drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Please consult your doctor if you have liver impairment/liver disease before taking Paraxin Suspension 60 ml.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment/kidney disease before taking Paraxin Suspension 60 ml.

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Children

Consult your doctor

Paraxin Suspension 60 ml should be used for children only if advised by the doctor.

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Heart

Caution

Paraxin Suspension 60 ml may be used in heart patients, but only when absolutely necessary due to its risk of serious side effects like bone marrow suppression. Close medical supervision and regular blood tests are essential during treatment.

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Geriatrics

Caution

Geriatric patients can take Paraxin Suspension 60 ml, but only when absolutely necessary and under strict medical supervision. Due to age-related risks like bone marrow suppression and slower drug metabolism, regular blood monitoring is essential during treatment.

What if I have taken an overdose of Paraxin Suspension 60 ml

In case of an accidental overdose, seek emergency medical help or call your local poison control centre immediately. Watch for signs of severe nausea, vomiting, or breathing difficulties.

Diet & Lifestyle Advise

  • Stay Well-Hydrated: Drink adequate fluids throughout the day, particularly if you experience diarrhoea or vomiting.
  • Choose Light Meals if Needed: If you experience nausea or stomach discomfort, smaller, bland meals may be easier to tolerate.
  • Avoid or Limit Alcohol: Alcohol may worsen symptoms such as nausea or dizziness and is best avoided during treatment unless your doctor advises otherwise.
  • Maintain a Balanced Diet: Eat a varied, nutritious diet to support your overall health while recovering from the infection.
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How Soon It Starts Working

The time required for Paraxin Suspension 60 ml to start to work: Paraxin Suspension 60 ml ideally shows its action within few hours after administration. The time for which the effects of Paraxin Suspension 60 ml last: The duration of action for Paraxin Suspension 60 ml is unknown.

What if you forget to take Paraxin Suspension 60 ml

If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Paraxin Suspension 60 ml oral suspension at controlled room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Shake the Suspension Well: Shake the bottle thoroughly before measuring each dose to ensure the medicine is evenly distributed.
  • Use an Accurate Measuring Device: Do not use a household spoon to measure the dose. Use the measuring device provided or an appropriate oral syringe.
  • Complete the Prescribed Course: Take Paraxin Suspension 60 ml for exactly the duration prescribed by your doctor. Do not stop treatment early unless your doctor tells you to do so.
  • Attend Recommended Blood Tests: If treatment is prolonged, your doctor may monitor your blood cell counts because Paraxin Suspension 60 ml can rarely cause serious blood-related complications.
  • Report Severe Diarrhoea: Contact your doctor promptly if you develop severe, persistent, watery, or bloody diarrhoea during or after treatment, as antibiotic-associated colitis can occur even after treatment has ended.

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor or pharmacist about all medicines you are taking before using Paraxin Suspension 60 ml:

  • Blood thinners (like warfarin): May increase the risk of severe bleeding.
  • Seizure medications (like phenytoin or phenobarbital): May increase the levels of these drugs in your body, leading to toxicity.
  • Iron supplements or Vitamin B12: May reduce your body's response to these supplements.
  • Other antibiotics (like penicillins): May reduce the overall effectiveness of both medications.
Critical
ChloramphenicolLomitapide
Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Paraxin- 60ml:
Taking Paraxin- 60ml with triazolam can increased the effects of Paraxin- 60ml.

How to manage the interaction:
Taking Triazolam with Paraxin- 60ml is not recommended, but can be taken together if prescribed by a doctor. In case you experience any unusual symptoms, consult a doctor. However, if you experience any unusual symptoms contact your doctor. Do not discontinue any medications without consulting a doctor.
ChloramphenicolLomitapide
Critical
How does the drug interact with Paraxin- 60ml:
Taking lomitapide with Paraxin- 60ml can significantly increase the blood levels of lomitapide.

How to manage the interaction:
Taking Paraxin- 60ml with Lomitapide is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, light colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
ChloramphenicolFlibanserin
Critical
How does the drug interact with Paraxin- 60ml:
Taking Flibanserin with Paraxin- 60ml may significantly increases the blood levels of flibanserin

How to manage the interaction:
Taking Paraxin- 60ml with Flibanserin is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, and fainting. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Paraxin- 60ml:
When Everolimus is taken with Paraxin- 60ml that may increase the risk of side effects.

How to manage the interaction:
Co-administration of Paraxin- 60ml with Everolimus can result in an interaction, but it can be taken if a doctor has advised it. If you experience any unusual symptoms like persistent cough, fever, chills, mouth ulcers, paleness, unusual bruising, bleeding or blood in stools or urine, it's important to contact a doctor. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Paraxin- 60ml:
Taking Naloxegol and Paraxin- 60ml can significantly increase the blood levels of naloxegol that may increase the risk of side effects.

How to manage the interaction:
Although taking Paraxin- 60ml and Naloxegol together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sweating, runny nose, or abdominal pain contact your doctor know right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Paraxin- 60ml:
When Lemborexant is taken with Paraxin- 60ml, may increase the blood levels of Lemborexant.

How to manage the interaction:
Although taking Paraxin- 60ml and Lemborexant together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you're having any of these symptoms like feeling down, having thoughts of hurting yourself, or having a headache, it's important to reach out to your doctor. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Paraxin- 60ml:
Taking Paraxin- 60ml and Ivacaftor may increase the blood levels of ivacaftor that increases risk of side effects.

How to manage the interaction:
Although taking Paraxin- 60ml and Ivacaftor together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes contact a doctor. Do not stop using any medications without a doctor's advice.
ChloramphenicolBrigatinib
Severe
How does the drug interact with Paraxin- 60ml:
Taking brigatinib with Paraxin- 60ml may increase the blood levels of brigatinib that may increase risk of side effects.

How to manage the interaction:
Co-administration of Paraxin- 60ml with Brigatinib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as paleness, fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, or pain and burning during urination. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Paraxin- 60ml:
Taking cladribine together with Paraxin- 60ml may increase the risk of infections.

How to manage the interaction:
There may be a possibility of interaction between Cladribine and Paraxin- 60ml, but it can be taken if prescribed by a doctor. If you have any of these symptoms - fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination, make sure to contact your doctor right away. Do not discontinue any medications without consulting a doctor.
ChloramphenicolHydrocodone
Severe
How does the drug interact with Paraxin- 60ml:
Taking Paraxin- 60ml and Hydrocodone can significantly increase the blood levels of cariprazine.

How to manage the interaction:
Although taking Paraxin- 60ml with Hydrocodone can possibly result in an interaction, it can be taken if your doctor has advised it. If you're having any of these symptoms like dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations feeling tired, having trouble moving, difficulty swallowing or having seizures, it's important to let your doctor know. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Paraxin Suspension 60 ml when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Paraxin Suspension 60 ml works by preventing the synthesis of essential proteins which are necessary for vital bacterial functions. Thus, it kills the bacteria and helps in treating and preventing the spread of infections.
Diarrhoea might be a side-effect Paraxin Suspension 60 ml. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
It is recommended to complete the course of Paraxin Suspension 60 ml even if you feel better, as it is an antibiotic. Leaving it in between may lead to even severe infection that will, in fact, stop responding to the antibiotic as well (antibiotic resistance).
Paraxin Suspension 60 ml may cause blood problems in some cases, which could lead to slow healing or infections. Consult your doctor if you have any concerns. Regular blood tests are advised while taking Paraxin Suspension 60 ml.
Use Paraxin Suspension 60 ml only as prescribed by the doctor. Do not use Paraxin Suspension 60 ml for longer durations. Consult your doctor if your condition does not improve or if it worsens.
No, you should avoid taking this medicine during pregnancy, particularly during the late stages, as it can cause serious blood disorders in the unborn baby. Talk to your doctor.
Grey baby syndrome is a rare but potentially life-threatening reaction to Paraxin Suspension 60 ml that can occur in newborns and neonates because their immature liver cannot process the medicine effectively. The medicine should not be used in this age group. Older infants may only receive it when specifically prescribed and closely monitored by a specialist.
It is best taken on an empty stomach, either 1 hour before or 2 hours after a meal. If it upsets your stomach, you can take it with a light meal. Talk to your doctor or pharmacist.
No, this medicine is an antibiotic and is only effective against bacterial infections. It will not cure viral illnesses like the cold, flu, or bronchitis. Talk to your doctor.
It is highly recommended to avoid alcohol while taking this medicine, as it can increase your risk of unpleasant side effects such as headaches, nausea, and vomiting. Talk to your doctor or pharmacist.
This medicine can occasionally affect your bone marrow's ability to produce blood cells. Regular blood tests allow your doctor to monitor your health and safety during treatment. Talk to your doctor.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi Dl 110034 INDIA
Other Info - PAR0028
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