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compositionComposition:CYCLOSPORINE-100MG
prescriptionPrescription Medicine
Panimun Bioral 100 mg Solution 50 ml

Panimun Bioral 100 mg Solution is used to prevent organ transplant rejection. It is also used to treat inflammation and pain associated with psoriasis and rheumatoid arthritis. This medicine contains cyclosporine, which works by suppressing the immune system. It also helps reduce rapid skin cell growth, pain, and inflammation. It may sometimes cause common side effects such as headaches, vomiting, nausea, loss of appetite, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CYCLOSPORINE-100MG

Manufacturer/Marketer :

Panacea Biotec Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Panimun Bioral 100 mg Solution

Panimun Bioral 100 mg Solution belongs to a group of medications called 'immunosuppressants,' primarily used to prevent organ rejection after a transplant. It is also used to treat symptoms associated with psoriasis and rheumatoid arthritis.

Panimun Bioral 100 mg Solution contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and lowers pain and inflammation in the joints.

Panimun Bioral 100 mg Solution may cause side effects like headaches, vomiting, nausea, loss of appetite and diarrhoea. Most of these side effects do not require medical attention and resolve over time. However, consult your doctor if the side effects persist or worsen.

To treat your condition effectually, continue taking Panimun Bioral 100 mg Solution for as long as your doctor has prescribed. Inform your doctor about your health condition and any medications you are taking to help rule out any potential/unpleasant side effects.

Uses of Panimun Bioral 100 mg Solution

Panimun Bioral 100 mg Solution is used to prevent organ rejection and treat psoriasis and rheumatoid arthritis. The detailed uses of Panimun Bioral 100 mg Solution are as follows:

  • Treatment of Organ Transplant Rejection: Panimun Bioral 100 mg Solution is used in the prevention of organ transplant rejection after liver, kidney, pancreas, lungs, heart, skin, and bone marrow transplants.
  • Treatment of Psoriasis: Panimun Bioral 100 mg Solution is used in the treatment of psoriasis. It helps reduce rapid skin cell growth and inflammation caused by psoriasis.
  • Treatment of Rheumatoid Arthritis: Panimun Bioral 100 mg Solution is used in the treatment of rheumatoid arthritis. It helps reduce pain and inflammation in the joints and slows down joint damage.

Key Benefits

  • Panimun Bioral 100 mg Solution suppresses the immune system to prevent the rejection of transplanted organs (e.g., kidney, liver, heart).
  • It is also used in bone marrow and stem cell transplantation to prevent graft rejection.
  • Panimun Bioral 100 mg Solution helps control immune overactivity in various autoimmune conditions by blocking immune cells that attack the body’s own tissues.
  • It reduces rapid skin cell growth and inflammation in severe psoriasis, leading to clearer skin and symptom relief.
  • This medicine reduces joint pain, inflammation, and slows down joint damage in patients with active rheumatoid arthritis unresponsive to other therapies.
  • It may also be used to treat severe atopic dermatitis, especially in patients who do not respond adequately to topical treatments.
  • Helps manage severe inflammatory eye diseases that can threaten vision by reducing immune-mediated damage.
  • It is used in certain cases of nephrotic syndrome (a kidney disorder causing excess protein loss in urine), especially when other treatments fail.
Side effects of Panimun Bioral 100 mg Solution 50 ml
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Using a cold compress may help relieve itching and inflammation associated with conjunctivitis.
  • A warm compress and washing the eyes with water can help with crusting on the eyelids.
  • Avoid wearing contact lens until you feel better; use spectacles instead.
  • Do not rub the eyes.
  • Practise good hand hygiene and avoid touching the eyes to prevent the spread of infection.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Increase protein intake by eating protein-rich foods like eggs, fish, lean meat, beans, and nuts to support nail strength.
  • Include biotin-rich foods like salmon, avocado, bananas, almonds, and whole grains in your diet to promote nail health.
  • Boost iron intake by consuming iron-rich foods like spinach, red meat, lentils, and fortified cereals to prevent iron deficiency.
  • Moisturize your nails and cuticles regularly by applying cuticle oil or hand cream multiple times a day.
  • Keep your nails short to reduce the risk of breakage and snagging.
  • Avoid biting your nails, as it can cause significant damage to your nails and cuticles.
  • Consider taking biotin supplements after consulting your doctor, as they may help strengthen brittle nails.

Directions for Use

  • Panimun Bioral 100 mg Solution can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Check the label for directions and use as advised by your doctor.
  • Measure the prescribed dose of Panimun Bioral 100 mg Solution using the dosing syringe. Mix it with apple or orange juice, stir well, and drink immediately.
  • Do not store the prepared mixture for later use.

How Panimun Bioral 100 mg Solution Works

Panimun Bioral 100 mg Solution contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and the production of interleukins (molecules involved in inflammation). Additionally, it also reduces pain and inflammation in the joints and slows down the joint damage caused by an overactive immune system.
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Panimun Bioral 100 mg Solution. It could lead to increased dizziness.

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Pregnancy

Caution

Panimun Bioral 100 mg Solution belongs to pregnancy category C. Consult your doctor before taking Panimun Bioral 100 mg Solution if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Panimun Bioral 100 mg Solution passes into breast milk. Avoid breastfeeding while taking Panimun Bioral 100 mg Solution.

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Driving

Caution

Panimun Bioral 100 mg Solution may cause dizziness. Drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Panimun Bioral 100 mg Solution is not recommended for children as efficacy and safety have not been established.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems

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Geriatrics

Caution

Panimun Bioral 100 mg Solution should be given to elderly patients only if prescribed by a doctor. If you have any concerns, please consult your doctor.

What if I have taken an overdose of Panimun Bioral 100 mg Solution

Do not take more than the prescribed dose of Panimun Bioral 100 mg Solution as it may cause an overdose. Symptoms of overdose include vomiting, drowsiness, headache, fast heartbeat, yellowing of the skin/eyes, and swelling of the arms, hands, feet, ankles, or lower legs. If you suspect you have taken an overdose or experience any of these symptoms, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Eat foods rich in quercetin (a flavonoid) such as apples, cherries, broccoli, spinach, and blueberries.
  • Consuming food rich in probiotics helps in developing the immune system against allergies.
  • Limit intake of food that might trigger allergies, such as dairy products, soy, eggs, and nuts.
  • Avoid consumption of foods with excess sugar to prevent flare-up inflammation.
  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
  • Reducing stress and maintaining a regular sleep pattern would be helpful.
  • Avoid getting in contact with harsh soaps, detergents, and rough fabrics.

Have a query?

How Soon It Starts Working

The time required for Panimun Bioral 100 mg Solution to start to work: The time required for Panimun Bioral 100 mg Solution to show its action is unknown. The time for which the effects of Panimun Bioral 100 mg Solution last: The duration of action for Panimun Bioral 100 mg Solution is unknown.

What if you forget to take Panimun Bioral 100 mg Solution

If you miss a dose of Panimun Bioral 100 mg Solution, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not take a double dose to make up for the missed dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Panimun Bioral 100 mg Solution if you are allergic to any of the components.
  • Let your doctor know before using Panimun Bioral 100 mg Solution if you have/had liver or kidney problems, epilepsy, high blood pressure, low levels of magnesium, high levels of potassium, cancer, or infection.
  • Panimun Bioral 100 mg Solution may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising.
  • Before taking Panimun Bioral 100 mg Solution, inform your doctor if you have any type of cancer.
  • Consult your doctor before taking Panimun Bioral 100 mg Solution if you are pregnant or planning for pregnancy.
  • Panimun Bioral 100 mg Solution should not be taken by breastfeeding mothers as it passes into breast milk.
  • Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Drug-Drug Interactions

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Drug-Drug Interaction: Panimun Bioral 100 mg Solution may interact with other immunosuppressant medicines (tacrolimus), anti-gout (thiopurine), water pills/diuretics (amiloride, spironolactone), blood pressure-lowering pills (aliskiren), cholesterol-lowering pills (atorvastatin, pitavastatin, simvastatin), antibiotics (such as erythromycin or azithromycin), antifungals (voriconazole, itraconazole), medicines used for heart problems or high blood pressure (diltiazem, verapamil, amiodarone), used to treat menstrual problems (danazol), medicines used to treat gout (allopurinol), used to treat hepatitis C (colchicine, telaprevir).

Drug-Food Interaction: Avoid grapefruit or grapefruit juice while taking Panimun Bioral 100 mg Solution.

Drug-Disease Interaction: Inform your doctor if you have any pre-existing medical conditions such as high blood pressure, liver disease, or kidney disease.

CiclosporinBosentan
Critical
CiclosporinPitavastatin
Critical

Drug-Drug Interactions

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CiclosporinBosentan
Critical
How does the drug interact with Panimun Bioral 100 mg Solution 50 ml:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Panimun Bioral 100 mg Solution 50 ml with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinPitavastatin
Critical
How does the drug interact with Panimun Bioral 100 mg Solution 50 ml:
Coadministration of pitavastatin with Panimun Bioral 100 mg Solution 50 ml may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Pitavastatin with Panimun Bioral 100 mg Solution 50 ml is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
CiclosporinCidofovir
Critical
How does the drug interact with Panimun Bioral 100 mg Solution 50 ml:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Panimun Bioral 100 mg Solution 50 ml with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
CiclosporinSimvastatin
Critical
How does the drug interact with Panimun Bioral 100 mg Solution 50 ml:
Combining Panimun Bioral 100 mg Solution 50 ml and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Panimun Bioral 100 mg Solution 50 ml and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
CiclosporinBaricitinib
Critical
How does the drug interact with Panimun Bioral 100 mg Solution 50 ml:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Panimun Bioral 100 mg Solution 50 ml with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinAliskiren
Severe
How does the drug interact with Panimun Bioral 100 mg Solution 50 ml:
The combined use of aliskiren and Panimun Bioral 100 mg Solution 50 ml can significantly increase the blood levels and effects of aliskiren, which may lead to low blood pressure, hyperkalemia (high potassium levels) in the body. High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythms. If you are elderly, dehydrated, or have kidney disease, diabetes, or severe heart failure, you are more prone to develop hyperkalemia while taking these medications.

How to manage the interaction:
Taking aliskiren and Panimun Bioral 100 mg Solution 50 ml will lead to an interaction, they can be taken together if your doctor has prescribed them. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. It is advised to reduce intake of potassium-rich foods such as tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes, and potassium-containing salt substitutes.
CiclosporinFoscarnet
Severe
How does the drug interact with Panimun Bioral 100 mg Solution 50 ml:
Co-administration of foscarnet with Panimun Bioral 100 mg Solution 50 ml may increases the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between foscarnet and Panimun Bioral 100 mg Solution 50 ml, they can be taken together if your doctor has prescribed them. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
CiclosporinClarithromycin
Severe
How does the drug interact with Panimun Bioral 100 mg Solution 50 ml:
Co-administration of Clarithromycin with Panimun Bioral 100 mg Solution 50 ml may increase the effects of Panimun Bioral 100 mg Solution 50 ml.

How to manage the interaction:
Although there is a possible interaction, Clarithromycin can be taken with Panimun Bioral 100 mg Solution 50 ml if prescribed by the doctor. Consult the prescriber if you experience side effects such as diarrhea, nausea, vomiting, abdominal pain, dizziness, weakness, headache, tremors, fits, fever, sore throat, unusual bruising or bleeding, and increased or decreased urination. Do not discontinue the medication without a doctor's advice.
CiclosporinTenofovir alafenamide
Severe
How does the drug interact with Panimun Bioral 100 mg Solution 50 ml:
Co-administration of tenofovir alafenamide with Panimun Bioral 100 mg Solution 50 ml may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction, tenofovir alafenamide can be taken with Panimun Bioral 100 mg Solution 50 ml if prescribed by the doctor. However, consult the doctor if you experience side effects such as diarrhea, nausea, vomiting, abdominal pain, dizziness, weakness, headache, shaking, fits, fever, sore throat, unusual bruising or bleeding, and increased or decreased urination. Do not discontinue the medication without a doctor's advice.
CiclosporinRepaglinide
Severe
How does the drug interact with Panimun Bioral 100 mg Solution 50 ml:
Coadministration of repaglinide and Panimun Bioral 100 mg Solution 50 ml can increase the blood levels and effects of repaglinide.

How to manage the interaction:
Although taking repaglinide together with Panimun Bioral 100 mg Solution 50 ml can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact a doctor immediately if you experience headache, dizziness, drowsiness, anxiety, weakness, shaking, nausea, hunger, sweating, and palpitation. Do not discontinue any medicine without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[IMMUNOSUPPRESSANTS]

FAQs

Panimun Bioral 100 mg Solution is used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis conditions and in the treatment of psoriasis.

Panimun Bioral 100 mg Solution acts as an immunosuppressant, which helps in reducing inflammation and preventing joint stiffness, thereby providing relief from rheumatoid arthritis.

If you miss a dose of Panimun Bioral 100 mg Solution, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and take the scheduled dose instead.

Diarrhoea might be a side effect of Panimun Bioral 100 mg Solution. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Yes, the use of Panimun Bioral 100 mg Solution may cause abnormal facial and body hair growth as a common side effect. Please consult your doctor if you have any concerns.

Panimun Bioral 100 mg Solution is known to suppress the immune system. As a result, it increases the risk of infections and developing cancers, especially of the skin. Therefore, avoid prolonged exposure to sunlight by wearing suitable protective clothing and using sunscreen regularly.

Panimun Bioral 100 mg Solution may cause high blood pressure. Therefore, consult the doctor before taking Panimun Bioral 100 mg Solution if you have high blood pressure.

No, Panimun Bioral 100 mg Solution is not a steroid. It is an immunosuppressant.

Panimun Bioral 100 mg Solution may cause weight gain. Follow a healthy diet and exercise regularly to maintain proper weight. Consult your doctor if you have any concerns.

Panimun Bioral 100 mg Solution may cause fatigue. Eat a healthy diet, get regular exercise, manage stress, improve sleep habits, and quit smoking. Doing these may help cope with fatigue.

Yes, your doctor will recommend certain tests to check your body’s response to Panimun Bioral 100 mg Solution.

Panimun Bioral 100 mg Solution may cause side effects like headache, vomiting nausea, high blood pressure, loss of appetite (feeling unwell and upset stomach), and diarrhoea. Talk to your doctor if you experience these side effects persistently.

Use the measuring cup/dosing syringe provided with the pack to measure the prescribed dose of Panimun Bioral 100 mg Solution. Mix the solution/suspension in a glass of milk or orange juice, stir well, and consume immediately. Do not store the prepared mixture for later use.

You are advised to take Panimun Bioral 100 mg Solution for the duration prescribed by the doctor. The duration of treatment will depend upon your condition and response to the treatment.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Ambala- Chandigarh Highway, Lalru ? 140501, Punjab
Other Info - PAN0075
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