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compositionComposition:NAPROXEN-125MG
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Naprosyn Syrup is used to reduce pain and swelling in muscles and joints in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness in the backbone), cervical spondylitis (wear and tear of spinal discs in the neck) and acute gout (severe pain due to excess of uric acid). It contains Naproxen, which works by reducing the production of chemicals, known as prostaglandins, that cause pain and swelling. In some cases, you may experience indigestion, heartburn, stomach pain, nausea, headache, dizziness, drowsiness, bruising, itching, rash, and ringing in your ears. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

NAPROXEN-125MG

Manufacturer/Marketer :

RPG Life Sciences Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Naprosyn Syrup

Naprosyn Syrup is an oral liquid medication prescribed to relieve pain, swelling, and stiffness associated with various inflammatory conditions. It is commonly used to treat joint pain from arthritis, muscle aches, dental pain, and menstrual cramps. By targeting the source of swelling, this medication helps restore comfort and improve daily physical function.

For the best results, take this medicine exactly as directed by your doctor, keeping your dosing schedule consistent. Taking it with food or a glass of milk can help protect your stomach and prevent indigestion. Pairing this treatment with lifestyle changes, such as maintaining a balanced diet and staying well-hydrated, can further support your recovery.

While using this medicine, you may experience mild side effects like heartburn, nausea, or mild headaches. However, if you notice serious symptoms such as severe stomach pain, black stools, or breathing difficulties, you must stop taking the medicine and consult your doctor immediately.

Before starting this medication, talk to your doctor if you have a history of heart disease, high blood pressure, asthma, or kidney issues. Do not take this if you have had an allergic reaction to aspirin or other pain-relieving medicines, or if you are recovering from recent heart bypass surgery.

This medicine can interact with blood thinners, other pain medicines, and alcohol, which can significantly increase your risk of stomach bleeding. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, consult your doctor or pharmacist to ensure this medication is safe for you.

Uses of Naprosyn Syrup

Naprosyn Syrup is used in the treatment of joint pains and menstrual cramps. The detailed uses of Naprosyn Syrup are as follows:

  • Mild to moderate pain: It reduces pain from headaches, muscle aches, dental procedures, or menstrual cramps.
  • Osteoarthritis: It helps reduce joint pain, swelling, and stiffness, improving physical movement in everyday tasks.
  • Rheumatoid arthritis: It eases long-term joint inflammation, pain, and morning stiffness.
  • Ankylosing spondylitis: It relieves pain and inflammation in the spine and joints.
  • Gout attacks: It manages sudden, severe joint pain and swelling caused by gout flare-ups.

Key Benefits

  • Relieves pain and inflammation: Helps reduce pain, swelling, and inflammation, making daily activities more comfortable.
  • Improves movement: By reducing joint swelling and stiffness, it can support better movement and flexibility.
  • Easy to swallow: The oral suspension is easier to take than large tablets or capsules, especially for people who have difficulty swallowing pills.
  • Suitable for flexible dosing: The liquid form allows your doctor to make precise dose adjustments according to your needs.
  • Convenient for different age groups: The suspension can be a practical option for children, older adults, and others who have difficulty swallowing solid medicines.

Directions for Use

  • Naprosyn Syrup can be taken with or without food or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Measure the prescribed dose using a measuring cup to ensure accuracy and administer it orally.
  • Avoid using regular household spoons, as they may not measure the dose correctly.
  • Shake well before use.

How Naprosyn Syrup Works

Naprosyn Syrup belongs to a group of medicines that block certain enzymes in your body. These enzymes normally produce chemicals called prostaglandins, which trigger pain, fever, and swelling at the site of an injury or joint damage. By reducing the production of these chemicals, the medicine effectively lowers pain levels and calms inflammation, helping your body heal and move more freely.
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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Naprosyn Syrup as it may increase the risk of stomach bleeding and ulcer.

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Pregnancy

Unsafe

Naprosyn Syrup is a Category C pregnancy drug and is considered unsafe for pregnant women especially in the third trimester. However, please consult your doctor if you are pregnant.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Naprosyn Syrup as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Unsafe

Naprosyn Syrup may cause dizziness, tiredness, drowsiness or vision problems in some people. So, drive only if you are alert after taking Naprosyn Syrup.

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Liver

Caution

Take Naprosyn Syrup with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Naprosyn Syrup is not recommended for use in patients with moderate to severe and severe renal impairment whose creatinine clearance is less than 30 mL/min. The dose may be adjusted by your doctor as required.

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Children

Caution

Naprosyn Syrup can be prescribed to the children for the treatment of muscle/bone disorders for children (from 1 month), joint disease diseases (from 2 years) and for period pain in girl children (under 15 years). However, your doctor will decide whether Naprosyn Syrup should be given for the specific condition or not.

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Heart

Caution

Take Naprosyn Syrup with caution, especially if you have a history of heart diseases/conditions. The dose may be adjusted by your doctor as required.

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Geriatrics

Consult your doctor

Naprosyn Syrup can be safely used in elderly patients with proper monitoring and individualised care.

What if I have taken an overdose of Naprosyn Syrup

If you take too much of this medicine, seek immediate medical attention. Symptoms of an overdose may include severe stomach pain, extreme drowsiness, shallow breathing, or vomiting.

Diet & Lifestyle Advise

  • Protect your stomach: Always take this liquid medicine with food or a glass of milk to minimize stomach irritation.
  • Stay upright: Avoid lying down for at least 10 to 15 minutes after taking your dose to prevent heartburn or throat irritation.
  • Limit alcohol: Avoid drinking alcohol while taking this medicine, as the combination significantly increases the risk of stomach bleeding and ulcers.
  • Keep hydrated: Drink plenty of water throughout the day to support your kidneys, which process this medication.
  • Engage in low-impact exercise: If you are treating arthritis, try gentle activities like swimming or walking to keep joints flexible without worsening pain.
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How Soon It Starts Working

The time required for Naprosyn Syrup to start to work: Naprosyn Syrup ideally shows its action within 30 to 60 minutes after administration.

The time for which the effects of Naprosyn Syrup last: The effect of Naprosyn Syrup lasts for 8 to 12 hours.

What if you forget to take Naprosyn Syrup

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store the liquid at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Always shake the bottle vigorously before measuring your dose to ensure you receive the correct amount of active medicine.
  • Visually inspect the liquid before taking it; do not use it if you notice unusual color changes, clumping, or an unpleasant odor.
  • Do not combine this medicine with other over-the-counter pain relievers or cold remedies without checking, as they may contain similar ingredients and increase your risk of side effects.
  • Use caution when driving, riding a bicycle, or operating tools, as this medicine can make some people feel dizzy or drowsy.
  • Monitor your blood pressure regularly if you have hypertension, as this class of medication can sometimes raise blood pressure.

Drug-Drug Interactions

verifiedApollotooltip
  • May increase the risk of stomach ulcers or bleeding when combined with other pain medicines (like ibuprofen or aspirin) or blood thinners (like warfarin).
  • Can reduce the effectiveness of blood pressure medications (such as ACE inhibitors or beta-blockers) and water pills (diuretics).
  • May raise the levels and toxicity of other medicines in your body, such as lithium or methotrexate.

Drug-Drug Interactions

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How does the drug interact with Naprosyn Syrup 60 ml:
Coadministration of Ketorolac with Naprosyn Syrup 60 ml can increase the risk or severity of gastric bleeding and ulceration.

How to manage the interaction:
Taking Ketorolac with Naprosyn Syrup 60 ml together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Naprosyn Syrup 60 ml:
Taking cidofovir with Naprosyn Syrup 60 ml may increase the risk or severity of kidney problems

How to manage the interaction:
Taking Naprosyn Syrup 60 ml with Cidofovir is generally avoided as it can possibly result in an interaction. You should seek immediate medical attention if you develop signs and symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm.
How does the drug interact with Naprosyn Syrup 60 ml:
Co-administration of Naprosyn Syrup 60 ml with Meloxicam can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Meloxicam with Naprosyn Syrup 60 ml is not advised as it can possibly result in an interaction, it can be taken if your doctor has advised it. You should seek immediate medical attention if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness.
NaproxenTinzaparin
Severe
How does the drug interact with Naprosyn Syrup 60 ml:
Coadministration of Naprosyn Syrup 60 ml and Tinzaparin may increase the risk or severity of unusual bleeding problems.

How to manage the interaction:
Taking Naprosyn Syrup 60 ml and Tinzaparin together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor. Do not discontinue any medication without a doctor's advice.
How does the drug interact with Naprosyn Syrup 60 ml:
Co-administration of Naprosyn Syrup 60 ml and Ibrutinib can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Naprosyn Syrup 60 ml and Ibrutinib together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Naprosyn Syrup 60 ml:
Using Dasatinib with Naprosyn Syrup 60 ml may increase the risk or severity of bleeding problems.

How to manage the interaction:
Taking Dasatinib with Naprosyn Syrup 60 ml together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, red or black tarry stools, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Naprosyn Syrup 60 ml:
Coadministration of Naprosyn Syrup 60 ml and Etodolac can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Naprosyn Syrup 60 ml and Etodolac together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Naprosyn Syrup 60 ml:
Coadministration of Naprosyn Syrup 60 ml with flurbiprofen can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Naprosyn Syrup 60 ml with flurbiprofen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
NaproxenLomitapide
Severe
How does the drug interact with Naprosyn Syrup 60 ml:
Coadministration of Naprosyn Syrup 60 ml and Lomitapide may increase the risk or severity of liver problems.

How to manage the interaction:
Taking Naprosyn Syrup 60 ml and Lomitapide together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, confusion, diarrhea, vomiting, muscle weakness, muscle incoordination, tremor, blurred vision, ringing in the ear, excessive thirst, and/or increased urination, consult the doctor. Do not discontinue any medication without a doctor's advice.
NaproxenIopamidol
Severe
How does the drug interact with Naprosyn Syrup 60 ml:
Combine use of Naprosyn Syrup 60 ml and iopamidol may increase the effectiveness of iopamidol.

How to manage the interaction:
There may be a possible interaction between Naprosyn Syrup 60 ml and Iopamidol , but they can be taken together if they are prescribed by doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm and weakness consult the doctor. Do not discontinue any medication without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Taking this medicine with high-fat meals can slightly delay how quickly your body absorbs it, though it does not reduce the overall effectiveness of the dose.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[NON-STEROIDAL DRUG]

FAQs

Naprosyn Syrup is used to reduce pain and swelling in muscles and joints in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis (pain and stiffness in the backbone), cervical spondylitis (wear and tear of spinal discs in the neck) and acute gout (severe pain due to excess of uric acid).
Naprosyn Syrup works by blocking the action of the cyclo-oxygenase (COX) enzyme in the body that is involved in the production of certain chemical substances, such as prostaglandins, that cause pain and swelling.
No, Naprosyn Syrup is not recommended for use during pregnancy, especially in the last three months. It can affect and may harm the unborn baby (fetus). Therefore, if you are pregnant or planning for pregnancy, please inform your doctor before taking Naprosyn Syrup.
Yes, Naprosyn Syrup may increase the risk of heart problems such as heart attack and stroke, primarily when used in high doses or for prolonged duration. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking Naprosyn Syrup. However, it is recommended to take Naprosyn Syrup in the dose and for the duration as prescribed by your doctor. It should not be used by the patient who has had recent heart bypass surgery (coronary artery bypass graft - CABG).
No, you are not recommended to take Naprosyn Syrup with warfarin as co-administration of these two medicines may increase the risk of bleeding more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.
The doctor should decide the dose and duration based on your medical needs.
Please do not stop taking Naprosyn Syrup without consulting your doctor. To treat your condition effectually, continue taking Naprosyn Syrup for as long as your doctor prescribes it. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Naprosyn Syrup.
Naprosyn Syrup may not be safe for everyone. Don't take them if you're allergic to Naproxen, have a bleeding stomach ulcer, kidney disease, severe heart failure, or are in your third trimester of pregnancy. Also, avoid taking them if you're breastfeeding unless your doctor says it's okay. And don't combine them with other NSAIDs or blood thinners. Always check with your healthcare provider first to make sure it's safe for you to take Naproxen Tablets.
Taking more than the recommended dosage does not provide additional relief and can increase the risk of adverse effects.
Common side effects of Naprosyn Syrup may include indigestion, heartburn, stomach pain, nausea, headache, dizziness, drowsiness, bruising, itching, rash, and ringing in your ears. Most of these side effects of Naprosyn Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Yes, you can take it on an empty stomach, but doing so may increase your risk of stomach irritation or heartburn. To prevent stomach upset, it is highly recommended to take this liquid medicine with food or a glass of milk. Talk to your doctor or pharmacist if stomach discomfort persists.
You should avoid taking other anti-inflammatory pain relievers, such as ibuprofen or aspirin, while on this medication, as doing so increases the risk of stomach ulcers and bleeding. You may be able to take acetaminophen, but you should always talk to your doctor or pharmacist before combining pain medications.
You should use this medicine with caution if you have high blood pressure, as it can cause fluid retention and increase your blood pressure levels. Your doctor may need to monitor your blood pressure closely while you are using this treatment. Talk to your doctor before starting this medicine.
Do not take the medication if it has changed color, looks unusually cloudy, has clumps, or has an unusual smell. These can be signs that the liquid has spoiled or was not stored correctly. Talk to your pharmacist to get a replacement and learn how to safely dispose of the old bottle.
It is strongly advised to avoid drinking alcohol while taking this medicine. Alcohol increases the risk of stomach irritation, bleeding, and ulcers when combined with this type of pain reliever. Talk to your doctor if you have concerns about alcohol use.

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Country of origin

India

Manufacturer/Marketer address

463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai – 400 030. Maharashtra, INDIA
Other Info - NAP0020
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