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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Multizine 50 mg Tablet is used to treat schizophrenia and bipolar disorder (manic depression). It contains Thioridazine which works by decreasing abnormal excitement in the brain. In some cases, this medicine may cause side effects such as sleepiness, dry mouth, abnormal voluntary movements, weight gain, urinary retention, constipation, muscle stiffness, and tremor. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Whats That

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Composition :

THIORIDAZINE-50MG

Manufacturer/Marketer :

Triko Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Multizine 50 mg Tablet

Multizine 50 mg Tablet is used to treat schizophrenia or psychosis and bipolar disorder (manic depression). Schizophrenia is characterized by hallucinations symptoms (seeing or hearing things that are not real) and delusions (wrong beliefs). Manic episodes of excitement or depression characterize bipolar disorder. Multizine 50 mg Tablet prevents the occurrence of these symptoms. 

Multizine 50 mg Tablet contains ‘Thioridazine,’ which is an antipsychotic drug. It acts by blocking dopamine, a neurotransmitter in the brain responsible for developing schizophrenia and bipolar disorder symptoms. Multizine 50 mg Tablet  rebalances dopamine to improve thinking, mood and behaviour. It also blocks the other natural substance receptors in the brain, such as histamine and muscarinic, thereby preventing nausea and vomiting.

Take Multizine 50 mg Tablet as prescribed by your doctor. You are advised to take Multizine 50 mg Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience common side effects such as sleepiness, orthostatic hypotension (sudden lowering of blood pressure on standing), dry mouth, abnormality of voluntary movements, weight gain, urinary retention, constipation, muscle stiffness, and tremor. Most of these side effects of Multizine 50 mg Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Do not take Multizine 50 mg Tablet if you are allergic to Thioridazine or any other ingredients present in it. Before taking Multizine 50 mg Tablet , talk to your doctor if you or your family have a history of blood clots, stroke or heart diseases and if you are above 65 years old and have a history of dementia (memory loss). Multizine 50 mg Tablet is not recommended during pregnancy as it may affect the unborn baby. Tell your doctor if you are breastfeeding before taking Multizine 50 mg Tablet . It is not recommended for use in children under 1 year of age. Multizine 50 mg Tablet contains lactose, so it should not be given to people who are intolerant to some sugars. Please do not stop taking Multizine 50 mg Tablet without your doctor’s advice, as it may lead to withdrawal symptoms.

Uses of Multizine 50 mg Tablet

Treatment of Schizophrenia (mental illness), Bipolar disorder (manic depression).

Directions for Use

• Multizine 50 mg Tablet can be taken with food or immediately after a meal.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Multizine 50 mg Tablet as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Multizine 50 mg Tablet works by helping to restore the balance of certain natural substances in the brain. The key action of Multizine 50 mg Tablet is to block the dopamine receptors (D2) in the brain and correct dopamine's overactivity. Altogether, Multizine 50 mg Tablet may help decrease hallucinations and help you think more clearly and positively about yourself, feel less agitated and take a more active part in everyday life. On the other hand, it also blocks histamine H1 and muscarinic M1 receptors in the vomiting centre, thereby preventing nausea and vomiting.

How Multizine 50 mg Tablet Works

Multizine 50 mg Tablet contains ‘Thioridazine,’ which is an antipsychotic drug. It acts by blocking dopamine, a neurotransmitter in the brain responsible for developing schizophrenia and bipolar disorder symptoms. Multizine 50 mg Tablet  rebalances dopamine to improve thinking, mood and behaviour. It also blocks the other natural substance receptors in the brain, such as histamine and muscarinic, thereby preventing nausea and vomiting.

Storage

Keep Multizine 50 mg Tablet out of the sight and reach of children.

What if I have taken an overdose of Multizine 50 mg Tablet

Take Multizine 50 mg Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include blurred vision, drooling, nasal congestion, dry mouth, yellow eyes, vision colour changes, rapid/irregular/slow heart rate, high/low blood pressure, difficulty breathing, constipation, nausea, loss of appetite, dizziness, drowsiness, seizures, tremors, weakness, fever, muscle spasms/stiffness, low body temperature and difficulty walking. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Multizine 50 mg Tablet if you are allergic (hypersensitive) to Multizine 50 mg Tablet or any ingredients present in it. Please consult your doctor before taking Multizine 50 mg Tablet if you are pregnant or planning to conceive and breastfeed. Elderly patients (above 65 years) with dementia-related psychosis (memory loss) treated with antipsychotic drugs are at increased risk of death. Multizine 50 mg Tablet injection is not recommended for treating patients with dementia-related psychosis. Do not abruptly stop taking the medication, as it may cause withdrawal symptoms, especially suicidal thoughts in young adults. If you are an asthmatic patient, please inform your doctor before taking a Multizine 50 mg Tablet injection, as it may cause life-threatening allergic-type reactions, including anaphylactic symptoms. Before taking Multizine 50 mg Tablet , talk to your doctor if you have a history of blood clots, alcohol or drug abuse, fits (seizures), Parkinson's disease, hypothyroidism (reduced activity of the thyroid gland), stroke or heart diseases and glaucoma (increased pressure in the eye).

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Multizine 50 mg Tablet:
Combining Ciprofloxacin with Multizine 50 mg Tablet can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Ciprofloxacin with Multizine 50 mg Tablet is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Multizine 50 mg Tablet:
Co-administration of Multizine 50 mg Tablet together with Terbinafine can increase the blood levels of Multizine 50 mg Tablet and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Multizine 50 mg Tablet and Terbinafine is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Multizine 50 mg Tablet:
Taking oxytocin with Multizine 50 mg Tablet can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Oxytocin with Multizine 50 mg Tablet is not recommended, but should be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Multizine 50 mg Tablet:
Taking Multizine 50 mg Tablet with fluvoxamine may significantly increase the blood levels of Multizine 50 mg Tablet and cause an irregular heart rhythm

How to manage the interaction:
Although Fluvoxamine with Multizine 50 mg Tablet is not recommended, but can be taken together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath contact your doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Multizine 50 mg Tablet:
When Multizine 50 mg Tablet is taken with Clobazam, may increase the blood levels of Multizine 50 mg Tablet and cause an irregular heart rhythm.

How to manage the interaction:
Co-administration of Clobazam and Multizine 50 mg Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Multizine 50 mg Tablet:
Taking Multizine 50 mg Tablet and celecoxib may increases the blood levels of Multizine 50 mg Tablet which may cause irregular heart rhythm.

How to manage the interaction:
Taking Celecoxib with Multizine 50 mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Multizine 50 mg Tablet:
Coadministration of Multizine 50 mg Tablet and Tetrabenazine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Multizine 50 mg Tablet and Tetrabenazine together is not recommended as it can lead to an interaction, but it can be taken if your doctor advises. However, contact your doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhoea, or vomiting. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Multizine 50 mg Tablet:
Combining Tacrolimus with Multizine 50 mg Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tacrolimus with Multizine 50 mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Multizine 50 mg Tablet:
Taking Trazodone with Multizine 50 mg Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Trazodone with Multizine 50 mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Multizine 50 mg Tablet:
Combining Ceritinib with Multizine 50 mg Tablet can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Ceritinib with Multizine 50 mg Tablet is not recommended as it can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Monitor your mood. Keep track of your mood regularly, including factors such as sleep, medicine and activities that can impact your mood. Exercise daily.
  • Exercise is nice to relieve tension. It can also avoid the weight gain that can be a side effect of your bipolar medication.
  • You may also practice calming techniques such as meditation and deep breathing exercises.
  • Get some normal sleep. Having enough sleep will help to stabilize your mood.
  • Eat a healthy diet. Certain foods may affect your mood more than others. Consider keeping a food log to track what you eat and how certain foods make you feel. Talk to your doctor or nutritionist about foods that may help stabilize your mood.
  • Stay optimistic. It will take time for your symptoms to improve after you start bipolar therapy, but you will feel relaxed knowing that you will get better and that the worst is most definitely behind you.
  • A person should take a healthy diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils and low-fat dairy products will help to keep a person in good health.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS
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Alcohol

Unsafe

Alcohol may worsen the condition and increase the risk of side effects while using Multizine 50 mg Tablet .

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Pregnancy

Caution

Multizine 50 mg Tablet is a category C pregnancy drug; using Multizine 50 mg Tablet during pregnancy may affect your unborn baby. Please consult your doctor before taking Multizine 50 mg Tablet if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Multizine 50 mg Tablet is known to pass through the breast milk. So, it is recommended not to be taken during breastfeeding. However, your doctor may prescribe it for you during breastfeeding if he/she feels that the benefits to you outweighs the risk.

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Driving

Unsafe

Multizine 50 mg Tablet may cause drowsiness, and dizziness in some cases, especially in elderly patients. If you are affected, do not drive or operate dangerous machinery after taking Multizine 50 mg Tablet .

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Liver

Caution

Multizine 50 mg Tablet should be used with caution if you have liver disease. Your doctor may adjust the dose of this medicine based on your condition.

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Kidney

Caution

Multizine 50 mg Tablet should be used with caution if you have kidney disease. Your doctor may adjust the dose of this medicine based on your condition.

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Children

Caution

Multizine 50 mg Tablet is not recommended for children below 1 year of age. Children aged 1 and above can be given Multizine 50 mg Tablet but take it only in dose and duration prescribed by your doctor.

Have a query?

FAQs

Multizine 50 mg Tablet is used to treat schizophrenia or psychosis and bipolar disorder (manic depression).

Multizine 50 mg Tablet contains ‘Thioridazine,’ an antipsychotic drug that blocks dopamine, a neurotransmitter in the brain responsible for developing schizophrenia and bipolar disorder symptoms. Multizine 50 mg Tablet  rebalances dopamine to improve thinking, mood, and behaviour.

You are not recommended to stop taking Multizine 50 mg Tablet without consulting your doctor. It may cause withdrawal symptoms such as palpitations (the sensation that the heart skipped a beat or extra beat), anxiety, confusion, difficulty sleeping and tremors. Therefore, take Multizine 50 mg Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Multizine 50 mg Tablet , please consult your doctor so that the dose may be gradually reduced.

Multizine 50 mg Tablet is not recommended for patients suffering from myasthenia gravis (severe muscle weakness) as it may worsen the condition. Therefore, inform your doctor if you have myasthenia gravis before taking Multizine 50 mg Tablet .

Multizine 50 mg Tablet may increase your body weight. So, while taking Multizine 50 mg Tablet keep a check on your body weight. Also, monitor your blood sugar and cholesterol levels.

Multizine 50 mg Tablet can decrease anxiety, irritability or agitation. However, you should consult a doctor before using Multizine 50 mg Tablet for any condition.

No, Multizine 50 mg Tablet should be taken with caution, especially in elderly patients with dementia, as Multizine 50 mg Tablet is known to cause an increased death rate in such patients.

Multizine 50 mg Tablet is known to cause changes in blood sugar levels. If you have diabetes and are taking Multizine 50 mg Tablet , please regularly monitor your blood sugar level to avoid any unpleasant side effects of Multizine 50 mg Tablet .

Taking more Multizine 50 mg Tablet than your required dose leads to an overdose. Symptoms of overdose include blurred vision, drooling, nasal congestion, dry mouth, yellow eyes, vision changes, rapid/irregular/slow heart rate, high/low blood pressure, difficulty breathing, constipation, nausea, loss of appetite, dizziness, drowsiness, seizures, tremors, weakness, fever, muscle spasms/stiffness, low body temperature, and difficulty walking. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention, even if there are no symptoms.

The common side effects of Multizine 50 mg Tablet are sleepiness, drowsiness, orthostatic hypotension (sudden blood pressure lowering on standing), dry mouth, abnormality of voluntary movements, weight gain, urinary retention, constipation, muscle stiffness, and tremor. Please consult your doctor if any of these side effects persist or worsen.

Multizine 50 mg Tablet is not suitable for everyone, particularly pregnant and breastfeeding women, who should use it with caution only if advised by a doctor. Children under 2 years old should not take Multizine 50 mg Tablet due to potential health risks. Additionally, elderly patients with dementia-related psychosis should avoid Multizine 50 mg Tablet due to an increased risk of adverse effects. Patients with certain medical conditions, such as cardiac disorders, comatose or severe drug-induced depressed states, uncorrected hypokalaemia, severe photosensitivity, and serious haematological conditions, should also avoid Multizine 50 mg Tablet . If you belong to any of these groups, consult your doctor to discuss alternative treatment options.

Multizine 50 mg Tablet is not recommended for elderly patients with dementia-related psychosis. It should be used with caution in elderly patients aged 65 and above under the guidance of a doctor.

It is not advised to use Multizine 50 mg Tablet on children under two years old. It should be used with caution in children and adolescents (aged 2 to 18) after consulting the doctor.

Multizine 50 mg Tablet can cause drowsiness, which is a common side effect. If you experience drowsiness, taking precautions is essential to ensure your safety. Avoid driving, operating heavy machinery, or engaging in activities that require alertness. To minimize daytime drowsiness, take the medication at bedtime. Regular exercise, fresh air, and avoiding alcohol and other sedatives can also help you stay alert. If drowsiness persists or affects your daily activities, consult your doctor for guidance.

Country of origin

India
Other Info - MUL0114

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