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compositionComposition:THIORIDAZINE-50MG
prescription
Prescription Medicine
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Multizine 50 mg Tablet is used to treat schizophrenia and bipolar disorder (manic depression). It contains Thioridazine which works by decreasing abnormal excitement in the brain. In some cases, this medicine may cause side effects such as sleepiness, dry mouth, abnormal voluntary movements, weight gain, urinary retention, constipation, muscle stiffness, and tremor. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

THIORIDAZINE-50MG

Manufacturer/Marketer :

Triko Pharmaceuticals

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Multizine 50 mg Tablet

Multizine 50 mg Tablet is an oral prescription medication primarily used to manage severe symptoms of schizophrenia. It is typically prescribed to treat this condition when other antipsychotic medicines have failed to provide relief or have caused troublesome side effects. By helping to calm overactive nerve signals in the brain, it supports a clearer thought process and calmer behaviour.

To get the best results, you must take Multizine 50 mg Tablet consistently and exactly at the times prescribed by your doctor. You can take this medication with or without food, but it is best to choose one way and stick to it daily. Incorporating a steady routine, staying hydrated, and avoiding extreme heat can also help support your overall well-being while taking this medication.

While taking Multizine 50 mg Tablet , you may experience common side effects like sleepiness, dry mouth, or mild dizziness. However, if you notice serious symptoms such as an irregular heartbeat, severe muscle stiffness, high fever, or uncontrollable body movements, you must contact your doctor right away.

Talk to your doctor before starting this medicine if you have a history of heart conditions, seizures, or liver damage. Do not take this if you have a known history of severe heart rhythm problems, or if you are taking other medications that are known to alter your heartbeat.

This medication can interact with other drugs that cause drowsiness, alcohol, and medicines that affect your heart rhythm, increasing your risk of serious side effects. Smoking may also affect how Multizine 50 mg Tablet is broken down in the body and may alter its effectiveness. Tell your doctor about all medicines you take and whether you smoke before starting treatment. If you are pregnant, breastfeeding, or an elderly individual, you should consult your doctor before starting Multizine 50 mg Tablet to ensure it is safe for you.

Uses of Multizine 50 mg Tablet

Multizine 50 mg Tablet is used in the treatment of schizophrenia. The detailed uses of Multizine 50 mg Tablet are as follows:

  • Schizophrenia (treatment-resistant): Multizine 50 mg Tablet helps control severe mental symptoms like hearing voices, seeing things that are not there, and having false beliefs, especially when other medications have not worked.

Key Benefits

Multizine 50 mg Tablet offers significant relief for individuals dealing with severe psychiatric symptoms, helping them regain control over their daily lives. The following are the benefits of this medication:

  • Helps reduce hallucinations and disturbing thoughts.
  • Improves clear thinking and focus on daily tasks.
  • Reduces anxiety, tension, and confusion, making it easier to communicate with others.
  • Helps control severe agitation and impulsive behaviour.
  • Promotes a calmer and more stable state of mind.

Directions for Use

  • Multizine 50 mg Tablet can be taken with food or immediately after a meal.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Multizine 50 mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Multizine 50 mg Tablet Works

Multizine 50 mg Tablet belongs to a group of medicines known as phenothiazines. It works by targeting specific natural chemicals in the brain, primarily one called dopamine. An overabundance of dopamine activity is closely linked to the severe hallucinations, confusion, and agitation experienced in schizophrenia. By blocking dopamine receptors in specific brain pathways, Multizine 50 mg Tablet helps restore a healthier balance of brain chemistry. This action reduces the intensity of false perceptions and disorganised thinking, helping you feel more grounded and in control.
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Alcohol

Unsafe

Alcohol may worsen the condition and increase the risk of side effects while using Multizine 50 mg Tablet .

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Pregnancy

Caution

Multizine 50 mg Tablet is a category C pregnancy drug; using Multizine 50 mg Tablet during pregnancy may affect your unborn baby. Please consult your doctor before taking Multizine 50 mg Tablet if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Multizine 50 mg Tablet is known to pass through the breast milk. So, it is recommended not to be taken during breastfeeding. However, your doctor may prescribe it for you during breastfeeding if he/she feels that the benefits to you outweighs the risk.

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Driving

Unsafe

Multizine 50 mg Tablet may cause drowsiness, and dizziness in some cases, especially in elderly patients. If you are affected, do not drive or operate dangerous machinery after taking Multizine 50 mg Tablet .

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Liver

Caution

Multizine 50 mg Tablet should be used with caution if you have liver disease. Your doctor may adjust the dose of this medicine based on your condition.

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Kidney

Caution

Multizine 50 mg Tablet should be used with caution if you have kidney disease. Your doctor may adjust the dose of this medicine based on your condition.

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Children

Caution

Multizine 50 mg Tablet is not recommended for children below 1 year of age. Children aged 1 and above can be given Multizine 50 mg Tablet but take it only in dose and duration prescribed by your doctor.

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Heart

Unsafe

Multizine 50 mg Tablet is contraindicated in cardiac patients due to its adverse effects.

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Geriatrics

Unsafe

Multizine 50 mg Tablet is not safe for use in elderly patients aged 65 or older due to its severe side effects.

What if I have taken an overdose of Multizine 50 mg Tablet

If you suspect an overdose, seek emergency medical help immediately. Overdose symptoms can be serious and may include severe drowsiness, rapid or irregular heartbeats, deep confusion, muscle twitching, or difficulty breathing.

Diet & Lifestyle Advise

  • Stay well hydrated: Drink plenty of water throughout the day. This helps relieve dry mouth and lowers the risk of constipation.
  • Rise slowly: Since this medicine can cause your blood pressure to drop suddenly when you stand up, take your time when rising from a sitting or lying position to prevent dizziness and falls.
  • Avoid extreme heat: Multizine 50 mg Tablet can make it harder for your body to cool down. Drink plenty of fluids, wear lightweight clothing, and avoid long periods in hot weather or heavy exercise.
  • Eat a heart-healthy diet: Make sure your diet includes foods rich in potassium and magnesium, such as bananas, leafy greens, and whole grains. Low levels of these minerals can increase the risk of heart rhythm problems.
  • Limit caffeine: Reduce your intake of coffee, tea, and soda, as caffeine can sometimes interfere with how this medicine affects your nervous system.
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How Soon It Starts Working

The time required for Multizine 50 mg Tablet to start to work: The time required for Multizine 50 mg Tablet to show its action is unknown. The time for which the effects of Multizine 50 mg Tablet last: The effect of Multizine 50 mg Tablet lasts for 8 to 12 hours.

What if you forget to take Multizine 50 mg Tablet

If you miss a dose of Multizine 50 mg Tablet , take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed one. Talk to your doctor or pharmacist if you are unsure.

Storage

•Keep the tablets away from moisture and direct sunlight.• Do not freeze the liquid form of this medicine.

Drug Warnings

  • Prioritise heart health monitoring: Your doctor will likely order regular electrocardiograms (ECGs) and blood tests to check your heart rhythm while you take Multizine 50 mg Tablet . Keep all of these appointments.
  • Do not stop taking this medicine suddenly: Stopping abruptly can cause withdrawal symptoms or make your condition worse. Your doctor will help you by gradually decreasing dose levels when it is time to stop.
  • Protect yourself from the sun: This medication can make your skin highly sensitive to sunlight. Wear protective clothing and apply sunscreen when going outdoors.
  • Inspect liquid formulations: If using the liquid form, always check the appearance before taking it. Do not use the medicine if you notice any unusual colour changes, cloudiness, or floating particles.
  • Avoid hazardous activities: Do not drive, operate heavy machinery, or perform dangerous tasks until you are certain how this medication affects your alertness and vision.
  • Report any vision changes promptly: Tell your doctor immediately if you notice blurred vision, difficulty seeing in dim light, or changes in your eyesight, as Multizine 50 mg Tablet has been associated with pigmentary retinopathy, particularly with prolonged use or higher doses.

Drug-Drug Interactions

verifiedApollotooltip
  • Medicines that affect heart rhythm (e.g., Amiodarone, Moxifloxacin, Olanzapine): Taking Multizine 50 mg Tablet with other drugs that alter your heart rhythm, such as certain antiarrhythmics, specific antibiotics, or other antipsychotics, can increase the risk of life-threatening irregular heartbeats.
  • Medicines that cause drowsiness (e.g., Zolpidem, Morphine, Lorazepam): Using this medicine with sleep aids, prescription pain relievers, or anxiety medications can lead to dangerous levels of sleepiness and slowed breathing.
ThioridazineOfloxacin
Critical
ThioridazineRanolazine
Critical

Drug-Drug Interactions

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ThioridazineOfloxacin
Critical
How does the drug interact with Multizine 50 mg Tablet:
Coadministration of Ofloxacin with Multizine 50 mg Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ofloxacin with Multizine 50 mg Tablet together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ThioridazineRanolazine
Critical
How does the drug interact with Multizine 50 mg Tablet:
When Multizine 50 mg Tablet is taken with Ranolazine, may significantly increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Ranolazine with Multizine 50 mg Tablet together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
ThioridazineFluvoxamine
Critical
How does the drug interact with Multizine 50 mg Tablet:
Taking Multizine 50 mg Tablet with fluvoxamine may significantly increase the blood levels of Multizine 50 mg Tablet and cause an irregular heart rhythm

How to manage the interaction:
Although Fluvoxamine with Multizine 50 mg Tablet is not recommended, but can be taken together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath contact your doctor immediately. Do not stop using any medications without consulting a doctor.
ThioridazineParoxetine
Critical
How does the drug interact with Multizine 50 mg Tablet:
Coadministration of Paroxetine with Multizine 50 mg Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Multizine 50 mg Tablet with Paroxetine is not recommended, but should be taken if advised by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ThioridazineSotalol
Critical
How does the drug interact with Multizine 50 mg Tablet:
Using Multizine 50 mg Tablet together with sotalol can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Sotalol with Multizine 50 mg Tablet is not recommended, consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
ThioridazineZiprasidone
Critical
How does the drug interact with Multizine 50 mg Tablet:
Co-administration of Multizine 50 mg Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Multizine 50 mg Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
ThioridazineAmiodarone
Critical
How does the drug interact with Multizine 50 mg Tablet:
The combination of Amiodarone and Multizine 50 mg Tablet may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Multizine 50 mg Tablet with Amiodarone is not recommended, please consult your doctor before taking it.
ThioridazineAlfuzosin
Critical
How does the drug interact with Multizine 50 mg Tablet:
Taking Alfuzosin with Multizine 50 mg Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Alfuzosin with Multizine 50 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ThioridazineFlecainide
Critical
How does the drug interact with Multizine 50 mg Tablet:
Coadministration of Flecainide with Multizine 50 mg Tablet can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Flecainide with Multizine 50 mg Tablet is not recommended, but it should be taken if advised by a doctor However, if you experience dizziness, shortness of breath, or palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ThioridazineLenvatinib
Critical
How does the drug interact with Multizine 50 mg Tablet:
Taking Lenvatinib and Multizine 50 mg Tablet together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Using Lenvatinib and Multizine 50 mg Tablet is not recommended, but they can be taken together if advised by your doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Consuming alcohol while taking Multizine 50 mg Tablet may increase drowsiness, lower blood pressure, and increase the risk of serious heart problems.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIPSYCHOTICS]

FAQs

Multizine 50 mg Tablet is used to treat schizophrenia or psychosis and bipolar disorder (manic depression).
Multizine 50 mg Tablet contains ‘Thioridazine,’ an antipsychotic drug that blocks dopamine, a neurotransmitter in the brain responsible for developing schizophrenia and bipolar disorder symptoms. Multizine 50 mg Tablet  rebalances dopamine to improve thinking, mood, and behaviour.
You are not recommended to stop taking Multizine 50 mg Tablet without consulting your doctor. It may cause withdrawal symptoms such as palpitations (the sensation that the heart skipped a beat or extra beat), anxiety, confusion, difficulty sleeping and tremors. Therefore, take Multizine 50 mg Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Multizine 50 mg Tablet , please consult your doctor so that the dose may be gradually reduced.
Multizine 50 mg Tablet is not recommended for patients suffering from myasthenia gravis (severe muscle weakness) as it may worsen the condition. Therefore, inform your doctor if you have myasthenia gravis before taking Multizine 50 mg Tablet .
Multizine 50 mg Tablet may increase your body weight. So, while taking Multizine 50 mg Tablet keep a check on your body weight. Also, monitor your blood sugar and cholesterol levels.
Multizine 50 mg Tablet can decrease anxiety, irritability or agitation. However, you should consult a doctor before using Multizine 50 mg Tablet for any condition.
No, Multizine 50 mg Tablet should be taken with caution, especially in elderly patients with dementia, as Multizine 50 mg Tablet is known to cause an increased death rate in such patients.
Multizine 50 mg Tablet is known to cause changes in blood sugar levels. If you have diabetes and are taking Multizine 50 mg Tablet , please regularly monitor your blood sugar level to avoid any unpleasant side effects of Multizine 50 mg Tablet .
Taking more Multizine 50 mg Tablet than your required dose leads to an overdose. Symptoms of overdose include blurred vision, drooling, nasal congestion, dry mouth, yellow eyes, vision changes, rapid/irregular/slow heart rate, high/low blood pressure, difficulty breathing, constipation, nausea, loss of appetite, dizziness, drowsiness, seizures, tremors, weakness, fever, muscle spasms/stiffness, low body temperature, and difficulty walking. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention, even if there are no symptoms.
The common side effects of Multizine 50 mg Tablet are sleepiness, drowsiness, orthostatic hypotension (sudden blood pressure lowering on standing), dry mouth, abnormality of voluntary movements, weight gain, urinary retention, constipation, muscle stiffness, and tremor. Please consult your doctor if any of these side effects persist or worsen.
Multizine 50 mg Tablet is not suitable for everyone, particularly pregnant and breastfeeding women, who should use it with caution only if advised by a doctor. Children under 2 years old should not take Multizine 50 mg Tablet due to potential health risks. Additionally, elderly patients with dementia-related psychosis should avoid Multizine 50 mg Tablet due to an increased risk of adverse effects. Patients with certain medical conditions, such as cardiac disorders, comatose or severe drug-induced depressed states, uncorrected hypokalaemia, severe photosensitivity, and serious haematological conditions, should also avoid Multizine 50 mg Tablet . If you belong to any of these groups, consult your doctor to discuss alternative treatment options.
Multizine 50 mg Tablet is not recommended for elderly patients with dementia-related psychosis. It should be used with caution in elderly patients aged 65 and above under the guidance of a doctor.
It is not advised to use Multizine 50 mg Tablet on children under two years old. It should be used with caution in children and adolescents (aged 2 to 18) after consulting the doctor.
Multizine 50 mg Tablet can cause drowsiness, which is a common side effect. If you experience drowsiness, taking precautions is essential to ensure your safety. Avoid driving, operating heavy machinery, or engaging in activities that require alertness. To minimize daytime drowsiness, take the medication at bedtime. Regular exercise, fresh air, and avoiding alcohol and other sedatives can also help you stay alert. If drowsiness persists or affects your daily activities, consult your doctor for guidance.
Dry mouth is a common side effect. You can manage this by sipping water frequently, chewing sugarless gum, or sucking on sugar-free hard candy. If it becomes severe or does not improve, talk to your doctor or pharmacist.
No, you should avoid alcohol entirely while taking Multizine 50 mg Tablet . Alcohol can cause severe drowsiness, dangerously lower your blood pressure, and increase the risk of serious heart rhythm problems. Talk to your doctor if you have concerns.
It may take several weeks of consistent use before you notice a significant improvement in your symptoms. Continue taking your medicine exactly as prescribed, and talk to your doctor if you do not notice any changes after a few weeks.
Multizine 50 mg Tablet can affect the electrical activity of your heart, which can lead to serious irregular heartbeats. Regular ECGs allow your doctor to monitor your heart's safety. Talk to your doctor to learn more about this monitoring.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed one and continue your normal schedule. Never take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you are unsure.
Yes, this medicine can affect your body's ability to sweat and cool down, which increases the risk of heatstroke. Avoid long exposure to extreme heat, drink plenty of fluids, and talk to your doctor if you feel overheated or dizzy.

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Country of origin

India
Other Info - MUL0114

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