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compositionComposition:SODIUM AMINOSALICYLATE-1000MG
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Prescription Medicine
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MONOPAS 150MG TABLET is used in the treatment of Tuberculosis (TB) in combination with other medicines. It works by exerting its bacteriostatic effect against Mycobacterium tuberculosis by competing with PABA for enzymes involved in folate synthesis, thereby suppressing bacterial growth and reproduction, ultimately leading to cell death. The common side effects may include nausea, vomiting, diarrhoea and abdominal pain. Most of these side effects gradually resolve overtime. However, consult the doctor if any symptoms persist or worsen.

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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

SODIUM AMINOSALICYLATE-1000MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About MONOPAS 150MG TABLET

MONOPAS 150MG TABLET is an oral tablet used as part of combination therapy to treat drug-resistant tuberculosis (TB), particularly when standard first-line TB medicines are not suitable or have not worked. It is considered a second-line or reserve anti-TB medicine and should always be used under specialist medical supervision together with other TB medicines. Tuberculosis treatment requires multiple medicines taken together for several months. Your doctor will decide the treatment duration based on your condition and response to therapy.

For MONOPAS 150MG TABLET to work effectively, you must take it with strict consistency and exactly at the times prescribed by your doctor. It is typically taken with food or a large glass of water to help protect your stomach from irritation. Making healthy lifestyle choices, such as eating nutrient-rich foods and getting plenty of rest, can support your body's recovery during treatment.

While taking MONOPAS 150MG TABLET, you may experience mild side effects like nausea or an upset stomach. However, you must contact your doctor immediately if you experience more serious issues, such as yellowing of your skin or eyes, a severe skin rash, or unusual swelling in your neck.

Talk to your doctor before starting MONOPAS 150MG TABLET if you have a history of kidney disease, liver disease, or stomach ulcers. Do not take this if you have severe kidney failure or have had severe allergic reactions to similar medications in the past.

MONOPAS 150MG TABLET can interact with other treatments, alcohol, and certain vitamins, which may increase your risk of liver strain or affect how nutrients are absorbed. Pregnant women, breastfeeding mothers, and elderly individuals should consult their doctor before taking MONOPAS 150MG TABLET to evaluate potential risks. MONOPAS 150MG TABLET may also be prescribed for children with tuberculosis under specialist supervision. The dose is carefully calculated according to the child's body weight and should only be determined by a healthcare professional. 

Uses of MONOPAS 150MG TABLET

MONOPAS 150MG TABLET is used in the treatment of tuberculosis. The detailed uses of MONOPAS 150MG TABLET are as follows:

  • Active Tuberculosis: MONOPAS 150MG TABLET is used to treat active tuberculosis infections in the body. When used alongside other medications, it helps stop the spread and growth of the bacteria causing the illness.
  • Drug-Resistant Tuberculosis: If standard medications fail to clear the infection, MONOPAS 150MG TABLET provides an alternative way to target and weaken resistant strains of tuberculosis bacteria.

Key Benefits

MONOPAS 150MG TABLET helps treat tuberculosis (TB) by slowing the growth of tuberculosis bacteria when used together with other anti-tuberculosis medicines. It plays an important role in the treatment of certain drug-resistant TB infections under specialist supervision.
Benefits may include:

  • Helps control tuberculosis by slowing the growth of tuberculosis bacteria.
  • Supports the treatment of certain drug-resistant tuberculosis infections when used as part of combination therapy.
  • Helps prevent the infection from worsening or spreading to other parts of the body.
  • Supports successful long-term TB treatment when taken exactly as prescribed.
  • Helps improve treatment outcomes when combined with other anti-tuberculosis medicines.
  • Promotes recovery and reduces the risk of complications by completing the full prescribed treatment course.
     
Side effects of Monopas 150mg Tablet
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Directions for Use

  • MONOPAS 150MG TABLET can be taken with or without food as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow MONOPAS 150MG TABLET as a whole with a glass of water.
  • Do not chew, crush or break it.

How MONOPAS 150MG TABLET Works

MONOPAS 150MG TABLET is an anti-tuberculosis medicine that works by blocking the bacteria from making folic acid, an essential nutrient they need to grow and multiply. It competes with a natural substance called para-aminobenzoic acid (PABA), disrupting folic acid production and slowing the growth of tuberculosis bacteria. This allows the body's immune system and other anti-tuberculosis medicines to work more effectively to eliminate the infection.
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Alcohol

Caution

Avoid consumption of alcohol while taking MONOPAS 150MG TABLET as it may cause unpleasant side effects.

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Pregnancy

Caution

Consult the doctor before use if you are pregnant as it should be used only if clearly needed, and the benefits must outweigh the potential risks.

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Breast Feeding

Caution

Consult the doctor before use if you are breastfeeding as it should be used only if clearly needed, and the benefits must outweigh the potential risks.

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Driving

Consult your doctor

Limited information is available. Please consult the doctor if you have any concerns.

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Liver

Caution

MONOPAS 150MG TABLET should be used with caution in patients with liver disorders. Please consult your doctor if you have a liver disorder or any concerns.

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Kidney

Caution

MONOPAS 150MG TABLET should be used with caution in patients with kidney disorders. Please consult your doctor if you have a kidney disorder or any concerns.

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Children

Safe if prescribed

MONOPAS 150MG TABLET is safe for children if prescribed by a doctor. The dose and duration may vary depending on the child’s weight and the severity of the child's medical condition.

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Heart

Caution

Please inform your doctor if you have heart problems before taking MONOPAS 150MG TABLET, as the sodium content may worsen heart or circulation issues and cause side effects such as fluid retention, increased blood pressure, dizziness, or irregular heartbeat, which can be more serious in individuals with cardiovascular conditions.

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Geriatrics

Caution

Please inform your doctor if you are geriatric before taking MONOPAS 150MG TABLET, as there is limited information available on its safety in this age group.

What if I have taken an overdose of MONOPAS 150MG TABLET

If you accidentally take more than your prescribed dose, call emergency services (112 in India) or go to the nearest hospital emergency department immediately. Do not wait for symptoms to appear. Take MONOPAS 150MG TABLET pack with you so healthcare professionals know exactly what you have taken.

Diet & Lifestyle Advise

  • Eat a nutrient-dense diet: Focus on high-protein foods like lean meats, beans, and eggs to help your body rebuild tissues and recover from the infection.
  • Avoid alcohol entirely: Alcohol increases stress on your liver, which can greatly raise the risk of severe liver damage when combined with tuberculosis medications.
  • Monitor your nutrition: Long-term treatment may reduce the absorption of vitamin B12 and, in some people, affect folate levels. Your doctor may recommend blood tests or supplements if needed.
  • Stay well-hydrated: Drink plenty of water throughout the day to support your kidneys as they filter and remove MONOPAS 150MG TABLET from your body.
health query

Have a query?

How Soon It Starts Working

The time required for MONOPAS 150MG TABLET to start to work: The time required for MONOPAS 150MG TABLET to show its action is clinically not established. The time for which the effects of MONOPAS 150MG TABLET lasts: The duration of MONOPAS 150MG TABLET effect is clinically not established.

What if you forget to take MONOPAS 150MG TABLET

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and resume your normal schedule. Do not take two doses at the same time to make up for a missed one. If you are unsure, talk to your doctor or pharmacist.

Storage

• Store MONOPAS 150MG TABLET according to the instructions provided with your specific product. Tablets are generally stored at room temperature in a cool, dry place.

Drug Warnings

  • Check tablet condition: Inspect your tablets before taking them. If they have turned brown, dark purple, or show other signs of discoloration, do not take them and consult your pharmacist.
  • Complete the full course: Even if you start feeling completely healthy, you must finish the entire duration of the treatment to prevent the tuberculosis bacteria from returning and becoming drug-resistant.
  • Keep up with lab tests: Attend all scheduled blood tests so your doctor can regularly check your liver, kidney, and thyroid function.
  • Inform your dentist or surgeon: Let any healthcare professional know you are taking MONOPAS 150MG TABLET before undergoing any surgeries or dental procedures.
  • Attend regular monitoring appointments: Keep all scheduled follow-up visits and blood tests. Regular monitoring helps your doctor check your liver function, kidney function, thyroid function, vitamin levels, and ensure MONOPAS 150MG TABLET is working safely throughout your tuberculosis treatment.
  • Use with caution in certain patients: MONOPAS 150MG TABLET should not be used in people with a previous severe allergic reaction to MONOPAS 150MG TABLET or similar medicines, or in those with severe kidney failure. People with severe liver disease should use MONOPAS 150MG TABLET only if their doctor determines that the benefits outweigh the risks. Inform your doctor before starting treatment if you have stomach ulcers, thyroid problems, kidney disease, or liver disease so that appropriate monitoring can be arranged.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Anti-tuberculosis medicines (e.g., isoniazid, pyrazinamide): Taking these medicines alongside MONOPAS 150MG TABLET may increase the risk of liver damage. Your doctor may monitor your liver function during treatment.
  • Vitamin B12 supplements: MONOPAS 150MG TABLET may reduce the absorption of vitamin B12. Your doctor may monitor your vitamin B12 levels during long-term treatment.
  • Cardiac glycosides (e.g., digoxin): MONOPAS 150MG TABLET may reduce the absorption and effectiveness of digoxin. Your doctor may adjust the timing of your medicines or monitor your treatment.
  • Antibiotics (e.g., rifampicin): When used together as part of tuberculosis treatment, your doctor will monitor your response closely, as treatment effectiveness and side effects may require regular assessment.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Acidic foods and beverages (e.g., citrus fruits, orange juice): Avoid consuming highly acidic foods or drinks close to the time of taking MONOPAS 150MG TABLET, as they may affect its absorption.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- INFECTIVES]

FAQs

MONOPAS 150MG TABLET is an anti-infective medication primarily used in the treatment of tuberculosis (TB), which is caused by the bacterium Mycobacterium tuberculosis. It works by inhibiting the growth of the bacteria, thereby reducing their ability to multiply and spread throughout the body.
MONOPAS 150MG TABLET contains sodium aminosalicylate. It exerts its bacteriostatic effect against Mycobacterium tuberculosis by competing with PABA for enzymes involved in folate synthesis. This suppresses bacterial growth and reproduction, ultimately leading to cell death and helping to clear the infection.
MONOPAS 150MG TABLET may cause side effects such as nausea, vomiting, diarrhoea, and abdominal pain. However, if these side effects persist or worsen, please consult the doctor.
No, you must not stop taking MONOPAS 150MG TABLET early. Stopping treatment too soon can allow the remaining bacteria to multiply and become resistant to medications. Always complete the entire course prescribed by your doctor.
It is best to take MONOPAS 150MG TABLET with food or right after a meal. This helps protect your stomach and reduces common side effects like nausea and stomach pain. Inform your doctor if you struggle with stomach upset.
If MONOPAS 150MG TABLET have changed color (for example, turning brown or dark purple), they may have lost their strength or degraded. Do not take them. Contact your doctor immediately.
No, you must avoid alcohol while taking MONOPAS 150MG TABLET. Both the infection and the treatment strain your liver, and drinking alcohol significantly increases the risk of severe liver damage.
Yes, in some cases, prolonged use of MONOPAS 150MG TABLET can affect your thyroid gland, leading to an underactive thyroid (hypothyroidism). Your doctor will monitor your thyroid levels with regular blood tests.
Some antacids can interfere with how your body absorbs MONOPAS 150MG TABLET. Consult your doctor before taking any antacids or indigestion remedies while on this treatment.
MONOPAS 150MG TABLET should only be used during pregnancy if your doctor decides that the benefits outweigh the risks to the unborn baby. Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Early signs of liver damage include yellowing of your skin or the whites of your eyes, dark-colored urine, pale stools, severe fatigue, or persistent nausea and vomiting. If you notice any of these signs, seek medical care immediately.

Disclaimer

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Reference

  1. Mayo Clinic Staff. Drg 20061680 Inhalation and Dosage Monograph. Rochester, MN: Mayo Foundation for Medical Education; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Aminosalicylate Sodium Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. National Center for Biotechnology Information (NCBI). Aminosalicylate Sodium Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Pugh DL, Jones ER, Martin WJ Pugh DL, Jones ER, Martin WJ. 1950. [Accessed on 22 Dec. 2025]Check here
  5. 4-Aminosalicylic acid. NIH. National Library of Medicine. National Center for biotechnology information. PMC PubMed Central. [Accessed on 16th September 2022]Check here
  6. Lucane Pharma. Electronic Medicines Compendium (EMC). [Revised in November 2019] [Accessed on 15th September 2022]Check here
  7. National Institute of Health (NIH). PASER- aminosalicylic acid granule, delayed release. [Revised in June 2010] [Accessed on 15th September 2022]Check here

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - MON0098
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