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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Mignar 25-MF Tablet is used to treat type 2 diabetes mellitus. It contains Miglitol and Metformin which work by decreasing glucose production in liver and intestinal glucose uptake and inhibiting intestinal enzymes that break complex sugars into simple sugars like glucose. In some cases, this medicine may cause side effects such as stomach pain, heartburn, diarrhoea, nausea, and vomiting. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Mignar 25-MF Tablet

Mignar 25-MF Tablet belongs to the class of medications called ‘antidiabetic drugs’ used to treat type 2 diabetes mellitus. Type 2 diabetes mellitus is a chronic or life-long condition in which blood sugar or glucose levels rise more than normal. It occurs when the body does not produce enough insulin (utilizes glucose to produce energy) or if produced, it cannot function properly in the body.

Mignar 25-MF Tablet contains Miglitol and Metformin. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Miglitol works by inhibiting intestinal enzymes that break complex sugars into simple sugars like glucose. Together, Mignar 25-MF Tablet can effectively prevent the rise in glucose levels in the body.

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Mignar 25-MF Tablet are flatulence (gas), diarrhoea, abdominal pain, feeling sick (nausea), being sick (vomiting) and loss of appetite. These side effects can be reduced if this medicine is taken with food or after a meal. However, if any of these side effects persist or get worse, inform your doctor immediately.

It is not recommended to take Mignar 25-MF Tablet if you are allergic to any contents of it. Mignar 25-MF Tablet is not recommended if you are having any intestinal problems such as inflammation, ulcers, blockage, hernia, liver problems, severe kidney impairment, uncontrolled diabetes, severe dehydration, severe infections, and a recent history of heart attack or heart failure. Mignar 25-MF Tablet is not recommended for children and adolescents below 18 years, pregnant women, and breastfeeding mothers. It should be used with caution in elderly people as they may require dose adjustments. Mignar 25-MF Tablet may interact with alcohol and worsen the condition. Mignar 25-MF Tablet may cause hypoglycemia (low glucose levels), so avoid driving if you develop weakness, dizziness, fast heartbeat, or decrease in alertness.

Uses of Mignar 25-MF Tablet

Treatment of Type 2 diabetes mellitus

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Directions for Use

• Mignar 25-MF Tablet can be taken with food or as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Mignar 25-MF Tablet as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Mignar 25-MF Tablet  is a combination of two drugs: Miglitol and Metformin. This combination therapy is preferred in patients with poorly controlled diabetes. It reduces blood glucose levels, especially post-prandial glucose levels (glucose levels after meals) in type 2 diabetes mellitus patients. An increase in post-prandial glucose levels can be a risk factor for diabetes complications such as tissue and organ damage. So, a decrease in glucose levels helps control diabetes, reduce this risk and improve healthy life.

How Mignar 25-MF Tablet Works

Mignar 25-MF Tablet contains Miglitol and Metformin. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Miglitol works by inhibiting intestinal enzymes that break complex sugars into simple sugars like glucose. Together, Mignar 25-MF Tablet can effectively prevent the rise in glucose levels in the body.

Storage

• Store in a cool and dry place away from sunlight.• Keep this medicine out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Mignar 25-MF Tablet
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Mignar 25-MF Tablet

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Mignar 25-MF Tablet may cause a rare and serious side effect ‘lactic acidosis’ (buildup of lactic acid in the blood), characterized by abdominal pain, muscle cramps, vomiting, severe fatigue, and difficulty breathing. It is a life-threatening condition that requires immediate medical attention. Inform your doctor if you have any severe liver or kidney problems as their normal functioning is required to eliminate excess lactic acid from the body.  Consumption of alcohol, prolonged fasting, dehydration, uncontrolled diabetes, serious infections, and liver problems increases the risk of lactic acidosis. If you have dehydration (severe loss of body fluids) due to severe vomiting, diarrhoea, exposure to heat, or fever, stop taking Mignar 25-MF Tablet and immediately seek medical attention. Mignar 25-MF Tablet may cause hypoglycemia (low blood sugar) and its symptoms include sweating, dizziness, palpitations (pounding heartbeat), and shivering, etc. Whenever you experience any of these symptoms, immediately consume candies or glucose biscuits rather than ordinary sugar. If your condition doesn’t improve, consult your doctor immediately.

Drug-Drug Interactions

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MetforminIopentol
Critical
MetforminIocetamic acid
Critical

Drug-Drug Interactions

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MetforminIopentol
Critical
How does the drug interact with Mignar 25-MF Tablet:
Co-administration of Iopentol with Mignar 25-MF Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Mignar 25-MF Tablet with Iopentol is not recommended, please consult your doctor before taking it.
MetforminIocetamic acid
Critical
How does the drug interact with Mignar 25-MF Tablet:
Co-administration of Mignar 25-MF Tablet and Iocetamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Mignar 25-MF Tablet with Iocetamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopromide
Critical
How does the drug interact with Mignar 25-MF Tablet:
Co-administration of Iopromide with Mignar 25-MF Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Mignar 25-MF Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
MetforminMetrizamide
Critical
How does the drug interact with Mignar 25-MF Tablet:
Co-administration of Mignar 25-MF Tablet with Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Mignar 25-MF Tablet with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, muscle cramps or pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetforminIobenzamic acid
Critical
How does the drug interact with Mignar 25-MF Tablet:
Co-administration of Mignar 25-MF Tablet and Iobenzamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Mignar 25-MF Tablet with Iobenzamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIoglycamic acid
Critical
How does the drug interact with Mignar 25-MF Tablet:
Co-administration of Ioglycamic acid with Mignar 25-MF Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Mignar 25-MF Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopydol
Critical
How does the drug interact with Mignar 25-MF Tablet:
Co-administration of Iopydol with Mignar 25-MF Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Mignar 25-MF Tablet with Iopydol is not recommended, please consult your doctor before taking it.
MetforminIoxitalamic acid
Critical
How does the drug interact with Mignar 25-MF Tablet:
Co-administration of Mignar 25-MF Tablet and Ioxitalamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Mignar 25-MF Tablet with Ioxitalamic acid is not recommended, please consult your doctor before taking it.
MetforminIopanoic acid
Critical
How does the drug interact with Mignar 25-MF Tablet:
Co-administration of Iopanoic acid with Mignar 25-MF Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Mignar 25-MF Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
MetforminIomeprol
Critical
How does the drug interact with Mignar 25-MF Tablet:
Co-administration of Iomeprol with Mignar 25-MF Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Mignar 25-MF Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, a quarter with proteins, and a quarter with whole grains.
  • Eat at regular intervals. Do not take the long gap between a meal or snack.
  • Monitor your blood sugar level regularly, especially when there are a lot of fluctuations.
  • Invest in at least 150 min of moderate-intensity physical activity and 15 minutes of high-intensity exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates containing whole-grain foods and increase intake of fruits and veggies and other fiber-enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in food like chips, crisps, pastries, biscuits, and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. You may use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil for frying.
  • Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga, or meditation to control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yogurt, fat-free milk, cheese, etc.).
  • Keep your blood pressure as normal (120/80) as possible as it reduces the risk of cardiovascular diseases in diabetes patients.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Mignar 25-MF Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

Consumption of alcohol may increase the risk of side effects and worsen the condition.

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Pregnancy

Caution

Mignar 25-MF Tablet is a category B medicine and may not cause harmful effects to the unborn baby. However, it should be used in pregnant women only if clinically needed.

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Breast Feeding

Unsafe

Mignar 25-MF Tablet should not be given to breastfeeding mothers as it may pass in breast milk and cause adverse effects in the nursing baby.

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Driving

Caution

Mignar 25-MF Tablet may impair alertness or decrease concentration, so avoid driving or operating heavy machinery in such cases.

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Liver

Caution

Mignar 25-MF Tablet should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Mignar 25-MF Tablet is not recommended for use in patients with severe kidney impairment. In patients with mild to moderate kidney diseases, your doctor may have to adjust the dose.

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Children

Unsafe

Mignar 25-MF Tablet is not recommended for children and adolescents below 18 years of age.

FAQs

Mignar 25-MF Tablet is used to treat type 2 diabetes mellitus.

Mignar 25-MF Tablet contains Miglitol and Metformin. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Miglitol works by inhibiting intestinal enzymes that break complex sugars into simple sugars like glucose. Together, Mignar 25-MF Tablet can effectively prevent the rise in glucose levels in the body.

Mignar 25-MF Tablet can be taken on an empty stomach. However, it is advised to take with food or after meals to reduce the bowel side-effects and increase its efficiency.

Inform your doctor before having an X-ray or CT scan that you are taking Mignar 25-MF Tablet . Some imaging scans may involve the use of the injection of contrast materials that contain iodine. Concomitant use of this injection with Mignar 25-MF Tablet may affect your kidney function. So, the doctor may advise you to stop Mignar 25-MF Tablet before the examination and will decide when to restart it.

Mignar 25-MF Tablet may cause hypoglycemia (low blood sugar level) characterized by sweating, dizziness, palpitations, shivering, confusion, irritability, etc. If you experience these symptoms, try to eat candies or glucose biscuits. If your condition doesn't improve, consult your doctor immediately.

Mignar 25-MF Tablet is recommended for the treatment of type 2 diabetes and not used for treating type 1 diabetes, a condition which occurs mainly due to deficiency of insulin.

Mignar 25-MF Tablet is safe when used as per the dose and duration advised by a doctor.

Mignar 25-MF Tablet causes side effects such as diarrhoea, abdominal pain, feeling sick (nausea), vomiting, and loss of appetite. However, these side effects are temporary and do not require any medical attention, as they will gradually reduce over time. Please, contact a doctor if these persist for longer durations.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai 400 026.
Other Info - MIG0041

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