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  3. Medrofem-10 Tablet 10's

Medrofem-10 Tablet 10's, Pack of 10 TabletS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Medrofem-10 Tablet 10's is used to treat the absence of menstrual periods (amenorrhea) and abnormal uterine bleeding. Besides this, it also prevents endometrial hyperplasia (thickening of the uterine lining with the risk of cancer) and overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy. It contains Medroxyprogesterone, which works by replacing the normal hormone medroxyprogesterone functions in the body and treating associated symptoms. It may sometimes cause side effects such as breast tenderness, swelling in other body parts, headaches, migraines, mood swings, depression, acne, tummy (abdominal) pain, back pain, and vaginal bleeding.

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Composition :

MEDROXYPROGESTERONE-10MG

Manufacturer/Marketer :

Chemo Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Medrofem-10 Tablet 10's

Medrofem-10 Tablet 10's is a female hormone known as progestin (a form of progesterone) that regulates ovulation (the release of an egg from an ovary). It treats the absence of menstrual periods (amenorrhea) and abnormal uterine bleeding. Besides this, it also prevents endometrial hyperplasia (thickening of the uterine lining with the risk of cancer) and overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.

Medrofem-10 Tablet 10's contains medroxyprogesterone. Medrofem-10 Tablet 10's works by replacing the normal hormone medroxyprogesterone functions in the body and treating associated symptoms.

Your doctor will advise your dose and how often you need to take this medication based on your medical condition. You may sometimes have breast tenderness, swelling in other body parts, headaches, migraines, mood swings, depression, acne, tummy (abdominal) pain, back pain, and vaginal bleeding. Most of these side effects of Medrofem-10 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Using Medrofem-10 Tablet 10's may increase the risk of blood clots. Make sure that before taking this medicine, you inform your doctor if you have or have had breast cancer, unusual bleeding in the vagina, liver disease, or any other health problems. If you are taking any other medicine or are allergic to any medication, please inform your doctor. Avoid smoking and alcohol to prevent any kind of unpleasant side-effect. Medrofem-10 Tablet 10's should not be used in heart disease or dementia patients because this medicine may increase your risk of developing these conditions.

Uses of Medrofem-10 Tablet 10's

Medrofem-10 Tablet 10's is used to treat Amenorrhea, irregular periods, uterine bleeding, endometrial hyperplasia, and endometriosis. The detailed uses of Medrofem-10 Tablet 10's are as follows:

  • Menstrual Cycle Regulation: Medrofem-10 Tablet 10's helps to regulate irregular menstrual cycles, treating conditions like amenorrhea by stabilising hormonal imbalances and promoting a regular menstrual cycle.
  • Hormonal Replacement Therapy: Medrofem-10 Tablet 10's may be used for hormone replacement therapy (HRT) to alleviate symptoms of menopause, such as hot flashes and mood changes, by regulating estrogen levels.
  • Endometriosis Treatment: Medrofem-10 Tablet 10's is also used to treat endometriosis symptoms, such as painful periods and irregular cycles, by regulating hormones and reducing discomfort.
  • Treatment of Abnormal Uterine Bleeding: By controlling hormone levels and possibly lowering excessive bleeding during menstruation, Medrofem-10 Tablet 10's can help manage abnormal uterine bleeding.

Directions for Use

• Medrofem-10 Tablet 10's can be taken with or without food, as advised by your doctor. • Your doctor will decide the appropriate dosage and timing of Medrofem-10 Tablet 10's based on your medical condition. • Swallow Medrofem-10 Tablet 10's as a whole with a glass of water. • Do not chew, crush, or break it.

Medicinal Benefits

Medrofem-10 Tablet 10's is a female hormone that regulates ovulation and menstruation in women. Medrofem-10 Tablet 10's helps in initiating the menses cycle (periods) in women who have not yet reached menopause. Besides this, it prevents overgrowth of the uterus in postmenopausal women who take estrogen as hormone replacement therapy (HRT). Medrofem-10 Tablet 10's is used to prevent thickening of the uterine lining in postmenopausal women receiving estrogens who have not removed their uterus through surgery. It also helps treat amenorrhea (cessation or irregular menses cycle for more than three months). It is also given in combination with estrogens as part of menopausal replacement therapy. The injection form of Medrofem-10 Tablet 10's is prescribed for treating abnormal uterine bleeding along with irregular or ceased menstrual cycles. The intravaginal gel form of Medrofem-10 Tablet 10's assists in reproductive technology for infertile women with progesterone deficiency or irregular or ceased menstrual cycle. The vaginal insert form of Medrofem-10 Tablet 10's supports early pregnancy and implantation of an embryo in the uterus. Off-label use of Medrofem-10 Tablet 10's helps in reducing the risk of preterm birth.

How Medrofem-10 Tablet 10's Works

Medrofem-10 Tablet 10's contains medroxyprogesterone. Medrofem-10 Tablet 10's works by replacing the normal hormone medroxyprogesterone functions in the body and treating associated symptoms.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Medrofem-10 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Use hot or cold packs on your breasts to help alleviate discomfort.
  • Choose a supportive, well-fitting bra, preferably one that has been professionally fitted.
  • Practice relaxation techniques to manage stress and anxiety that may accompany severe breast pain.
  • Limit or avoid caffeine consumption.
  • Eat a low-fat diet and focus on foods rich in complex carbohydrates.
  • Rubbing evening primrose oil on your breasts may help balance fatty acids in the cells and reduce pain.
  • Keep track of when your breast pain occurs and any other symptoms to determine if the pain is regular or not.
  • Vitamin E supplements may help reduce pain for women who experience pain linked to their menstrual cycle.
  • Over-the-counter pain relievers like acetaminophen or ibuprofen can provide relief, but be sure to consult your doctor for the correct dosage, as prolonged use may cause side effects.
Managing Medication-Triggered Thrombophlebitis (Inflammation of a vein): A Step-by-Step Guide:
  • If you have symptoms such as pain, swelling, redness, or warmth in your veins after taking medication, contact your doctor right once. Share information about your symptoms, medication regimen, and medical history.
  • Your doctor will then assess your medication regimen to determine if it's contributing to the thrombophlebitis. This assessment will help identify the best course of action to manage your condition and prevent further complications.
  • Your doctor may suggest certain diet and lifestyle changes to help manage your condition. This may include increasing your intake of foods rich in omega-3 fatty acids, staying hydrated, exercising regularly, and maintaining a healthy weight. Your doctor may also advise medications to reduce inflammation, prevent blood clots, or manage pain if necessary.
  • If your condition does not improve or persists, consult your doctor and report your condition. Your doctor will assess your progress, adjust your treatment plan if necessary, and provide appropriate advice to ensure the best possible outcome.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Keep your skin clean by gently washing your face two times daily and after sweating. Choose a mild and non-abrasive cleanser.
  • Use gentle alcohol-free skin care products. Avoid products that might irritate your skin such as exfoliants, astringents and toners.
  • Acne may also occur due to oil in the hair. Thus, if you have oily hair, shampoo more frequently than you do now and keep your hair away from face.
  • Keep your hands off your face as touching face throughout the day might worsen acne. Also, do not pick, squeeze or pop acne as it will prolong the healing process and increase the risk of dark spots and scarring.
  • Avoid tanning by applying a broad spectrum sunscreen and wearing sun-protective clothing when outdoors.

What if I have taken an overdose of Medrofem-10 Tablet 10's

Do not take more than the prescribed dose of Medrofem-10 Tablet 10's as it may cause overdose. The symptoms of overdose include seizures (fits), vomiting, nausea, trouble breathing and altered mental status. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Medrofem-10 Tablet 10's with estrogen should not be used to prevent heart disease, heart attacks, strokes, or dementia. Using Medrofem-10 Tablet 10's with estrogen may increase the chance of getting heart attacks, strokes, breast cancer, and blood clots. In some cases, using Medrofem-10 Tablet 10's with estrogen may produce dementia among women aged 65 and older. Do not use Medrofem-10 Tablet 10's if you are allergic to peanuts, have unusual vaginal bleeding, have had any cancer (breast or uterus cancer), or undergoing estrogen plus progestin treatment. Tell your doctor before using Medrofem-10 Tablet 10's if you have had a heart attack, stroke, blood clot, liver problems, kidney problems, are pregnant, breastfeeding or planning to get pregnant, asthma (wheezing), epilepsy (seizures), diabetes, migraine, endometriosis, lupus, heart problems, thyroid, or have high calcium levels in your blood. Use caution while driving a motor vehicle, as dizziness or drowsiness may occur. Tell your doctor about this if you use Medrofem-10 Tablet 10's before lab tests or biopsies, as it can affect the report values. Diagnostic tests of blood coagulation, thyroid, cholesterol, and glucose metabolism results might affect people using Medrofem-10 Tablet 10's.

Drug-Drug Interactions

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MedroxyprogesteroneEtretinate
Critical
MedroxyprogesteroneTranexamic acid
Critical

Drug-Drug Interactions

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MedroxyprogesteroneEtretinate
Critical
How does the drug interact with Medrofem-10 Tablet:
Taking Medrofem-10 Tablet and Etretinate may cause severe birth defects if the mother takes the medication during pregnancy.

How to manage the interaction:
Using etretinate and Medrofem-10 Tablet together is not recommended, but can be taken if prescribed by a doctor. However, if you experience unusual symptoms contact your doctor. Do not discontinue any medications without consulting a doctor.
MedroxyprogesteroneTranexamic acid
Critical
How does the drug interact with Medrofem-10 Tablet:
Taking Medrofem-10 Tablet acetate with Tranexamic acid may increase the risk of blood clots.

How to manage the interaction:
Taking Medrofem-10 Tablet with Tranexamic acid is not recommended but can be taken if prescribed by a doctor. Consult your doctor immediately if you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg. Do not stop using any medications without talking to your doctor.
MedroxyprogesteroneAcitretin
Critical
How does the drug interact with Medrofem-10 Tablet:
Coadministration of Acitretin with Medrofem-10 Tablet can increase the risk and severity of birth defects when taken by a pregnant woman.

How to manage the interaction:
Taking Acitretin with Medrofem-10 Tablet together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. Consult a doctor if you get pregnant while taking these medications. Do not discontinue any medications without consulting a doctor.
MedroxyprogesteroneMycophenolic acid
Severe
How does the drug interact with Medrofem-10 Tablet:
Coadministration of Medrofem-10 Tablet with mycophenolic acid may decrease the levels and effects of Medrofem-10 Tablet.

How to manage the interaction:
There could be a possible interaction between Mycophenolic acid and Medrofem-10 Tablet, but they can be taken together if your doctor has prescribed them. However, if you experience hot flashes, vaginal dryness, or abnormal bleeding consult a doctor. Do not discontinue any medications without a doctor's advice.
MedroxyprogesteroneSugammadex
Severe
How does the drug interact with Medrofem-10 Tablet:
When Medrofem-10 Tablet is taken with sugammadex, the effect of Medrofem-10 Tablet in the blood may decrease.

How to manage the interaction:
Taking Sugammadex with Medrofem-10 Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.
MedroxyprogesteroneBosentan
Severe
How does the drug interact with Medrofem-10 Tablet:
Taking Bosentan and Medrofem-10 Tablet may, reduce the blood levels and effects of Medrofem-10 Tablet.

How to manage the interaction:
Although there is a interaction between bosentan and Medrofem-10 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience hot flashes(feeling of heat in the body), dryness, or unusual bleeding, don't hesitate to reach out to your doctor. Do not stop using any medications without a doctor's advice.
MedroxyprogesteroneBrigatinib
Severe
How does the drug interact with Medrofem-10 Tablet:
Taking Medrofem-10 Tablet and Brigatinib may, reduce the blood levels and effects of Medrofem-10 Tablet.

How to manage the interaction:
Although taking Medrofem-10 Tablet and brigatinib together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience hot flashes(feeling of heat in the body), dryness, or unusual bleeding, don't hesitate to reach out to your doctor. Do not stop using any medications without a doctor's advice.
MedroxyprogesteroneFosamprenavir
Severe
How does the drug interact with Medrofem-10 Tablet:
Taking Medrofem-10 Tablet together with fosamprenavir may decrease the effects of fosamprenavir.

How to manage the interaction:
Although there is a possible interaction between Medrofem-10 Tablet and Fosamprenavir, you can take these medicines together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor right away. Do not stop using any medications without a doctor's advice.
MedroxyprogesteroneBoceprevir
Severe
How does the drug interact with Medrofem-10 Tablet:
Taking boceprevir and Medrofem-10 Tablet may, decrease the blood levels and effects of Medrofem-10 Tablet.

How to manage the interaction:
Although taking Medrofem-10 Tablet and Boceprevir together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms consult your doctor immediately. Do not discontinue any medications without consulting a doctor.
MedroxyprogesteroneTopiramate
Severe
How does the drug interact with Medrofem-10 Tablet:
When Medrofem-10 Tablet acetate is taken with Topiramate, it reduces the blood levels and effects of Medrofem-10 Tablet.

How to manage the interaction:
Co-administration of Medrofem-10 Tablet with Topiramate can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're taking birth control and experiencing symptoms like hot flashes, vaginal dryness, or abnormal bleeding, contact your doctor. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise and physical activity to minimize hot flushes and improve sleep. Besides this, weight-bearing exercises can help in making your bones strong. Aerobics, yoga, and activities like tai chi may help in relaxing the body and mind.
  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take a minimum sleep of 8 hours. 
  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
  • Try to be stress-free to improve your mood swings due to hormonal fluctuations. 
  • Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.
  • Try to apply vaginal lubricant or moisturizer if you have vaginal dryness.

Habit Forming

No

Therapeutic Class

HORMONES

Medrofem-10 Tablet 10's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

There is not enough scientific data available for Medrofem-10 Tablet 10's interaction with alcohol; hence, it is best to consult a doctor.

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Pregnancy

Caution

Contact the doctor before using Medrofem-10 Tablet 10's. Your doctor will decide whether Medrofem-10 Tablet 10's should be given to the pregnant woman or not, depending on her condition.

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Breast Feeding

Safe if prescribed

Clinical evidence suggests that Medrofem-10 Tablet 10's may pass into breast milk, but its risk is not established. So it is better to contact the doctor before using Medrofem-10 Tablet 10's.

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Driving

Unsafe

It is advised to drive with caution after taking Medrofem-10 Tablet 10's as it may interfere with driving capabilities. It can make you feel drowsy.

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Liver

Caution

Medrofem-10 Tablet 10's should be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Kidney

Caution

There is not enough scientific data available for Medrofem-10 Tablet 10's interaction with the kidney; hence it is best to consult a doctor.

bannner image

Children

Unsafe

Medrofem-10 Tablet 10's is not recommended for children below 12 years of age.

Have a query?

FAQs

Medrofem-10 Tablet 10's is used to regulate ovulation (the release of an egg from an ovary). It treats the absence of menstrual periods (amenorrhea) and abnormal uterine bleeding. Besides this, it also prevents endometrial hyperplasia (thickening of the uterine lining with the risk of cancer) and overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.

Medrofem-10 Tablet 10's helps in preparing the endometrium potential for pregnancy after ovulation. It thickens the lining of the endometrium to accept a fertilized egg. It also prevents muscle contractions of the uterus that would reject an egg in the uterus. So, if the body has a high progesterone level, ovulation will not occur then.

Abnormal uterine bleeding, irregular or missed periods (amenorrhea), abdominal pain during pregnancy, and frequent miscarriages are the signs of low progesterone. Additionally, low progesterone levels lead to high levels of estrogen, and women can have decreased sex drive, weight gain, or gallbladder problems.

Yes, Medrofem-10 Tablet 10's may cause weight gain. It can be due to water retention. If you feel that you are gaining a lot of weight while taking Medrofem-10 Tablet 10's, please consult your doctor.

Do not use Medrofem-10 Tablet 10's if you are allergic to peanuts, have unusual vaginal bleeding, have had any cancers (breast or uterus cancer), or undergoing estrogen plus progestin treatment. Tell your doctor before using Medrofem-10 Tablet 10's if you had a heart attack, stroke, blood clot, liver problems, pregnant, breastfeeding, or planning to get pregnant or allergic to Medrofem-10 Tablet 10's.

No, Medrofem-10 Tablet 10's is not a contraceptive. It should not be used as an effective form of birth control to prevent pregnancy.

Medrofem-10 Tablet 10's should be taken in the dose and duration as prescribed by the doctor.

Yes, Medrofem-10 Tablet 10's is a synthetic pregnant steroid and a derivative of progesterone.

Less serious but common side effects of Medrofem-10 Tablet 10's include headache, breast pain, irregular vaginal bleeding or spotting, stomach/abdominal cramps, bloating, nausea and vomiting, hair loss, fluid retention, and vaginal yeast infection.

Medrofem-10 Tablet 10's is safe and effective if used as per prescribed dose and duration. The patient should follow doctor’s recommendations. Do not exceed the recommended daily dose.

No, Medrofem-10 Tablet 10's does not cause withdrawal bleeding. However, if you notice symptoms such as bleeding or spotting even after completing the treatment, inform your doctor.

Take Medrofem-10 Tablet 10's as advised by your doctor. The dose and duration depends on your medical condition. It can be taken with or without food, but try to take it at the same time every day to maintain consistent levels of Medrofem-10 Tablet 10's in your body. Swallow it as whole with a glass of water. Do not break, crush or chew it.

Ideally, you should try not to miss a dose of Medrofem-10 Tablet 10's as missing a dose increases the chance of breakthrough vaginal bleeding or spotting (blood stain). However, if you miss a dose of Medrofem-10 Tablet 10's, take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for the missed dose.

Country of origin

India

Manufacturer/Marketer address

PLOT NO : 1, NEW AHMEDABAD INDL. ESTATE, VILL. MORRAIYA, TAL, Sanand Rd, Changodar, Gujarat 382213
Other Info - MED1541

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 5, 2025 | 12:41 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/product/3547/smpc
  2. https://www.medicines.org.uk/emc/files/pil.3547.pdf
  3. https://www.drugs.com/medroxyprogesterone.html

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