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Kofarest PD Syrup is used to treat cough associated with mucus. It contains Ambroxol, Guaiphenesin, and Terbutaline. Ambroxol works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Guaiphenesin increases the volume of fluid in the airways, reduces the stickiness of mucus, and removes it from the airways. Terbutaline relaxes muscles and widens the airways, making breathing easier. Together, they help relieve the cough.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMBROXOL-15MG+GUAIPHENESIN-50MG+TERBUTALINE-1.25MG

Manufacturer/Marketer :

Centaur Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Kofarest PD Syrup

Kofarest PD Syrup is a liquid medicine specifically designed to relieve wet coughs and chest congestion in children. It helps clear sticky mucus from the airways, making it easier for your child to breathe. Doctors typically prescribe this medicine to treat respiratory conditions where thick phlegm and narrowed airways cause discomfort.

To get the best results, always give this medicine to your child at the exact times recommended by your doctor. It can be taken with or without food, though giving it with food may help prevent mild stomach upset. Encouraging your child to drink plenty of warm fluids during the day can also help the medicine work more effectively to loosen congestion.

While this medicine is highly effective, your child may experience mild, temporary side effects like a slightly fast heartbeat, shaky hands, or mild stomach upset. If you notice any serious issues, such as severe skin rashes, swelling of the face, or extreme difficulty breathing, seek immediate medical attention.

Talk to your doctor before starting this medicine if your child has a history of heart problems, high blood pressure, overactive thyroid, or diabetes. Do not give this medicine to your child if they have a known allergy to any of the active ingredients.

This medicine can interact with certain other treatments, such as certain blood pressure medications or other cough syrups, which may increase the risk of side effects. While this is a paediatric formulation, if a pregnant or breastfeeding individual is handling the medicine, or if it is ever prescribed to other age groups, a doctor should be consulted first.

Uses of Kofarest PD Syrup

Kofarest PD Syrup is used to relieve wet coughs and chest congestion in children. The detailed uses of Kofarest PD Syrup are as follows:

  • Productive cough (wet cough): Kofarest PD Syrup thins out thick, stubborn mucus in the windpipe and lungs, making it easier for the child to cough it up.
  • Bronchitis: Kofarest PD Syrup helps soothe inflammation in the bronchial tubes by relaxing compressed airway muscles and clearing built-up phlegm.
  • Asthmatic cough: Kofarest PD Syrup relieves the sudden tightening of airway muscles that causes coughing fits and wheezing in children with asthma-like symptoms.

Key Benefits

Kofarest PD Syrup helps improve breathing in children by relaxing the airways and clearing excess mucus from the lungs. With regular use as directed, it helps relieve chest congestion, reduce coughing, and support a faster recovery from respiratory illnesses.

  • Makes Breathing Easier: By relaxing the muscles of the airways, this medicine helps open narrowed air passages, relieving chest tightness, wheezing, and breathing discomfort.
  • Loosens Thick Mucus: This medicine helps break down thick, sticky phlegm, making it easier for your child to cough it up and clear the airways more effectively.
  • Reduces Cough and Supports Recovery: By improving mucus clearance and easing airway obstruction, this medicine helps reduce tiring coughing fits, promotes restful sleep, and allows your child to recover more comfortably.
Side effects of Kofarest PD Syrup 100 ml
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
  • Gently massage the affected area using your hands or a massager.
  • Light exercises such as walking or climbing stairs may help the muscles return to normal.
  • Apply heat/ice to the affected area.
  • Drink electrolyte-rich fluids.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Exercise regularly and maintain a healthy weight.
  • Manage cholesterol and blood pressure.
  • Limit intake of caffeine and alcohol.
  • Avoid vaping and tobacco smoke.
  • Get enough sleep.
  • Talk to your doctor about antiarrhythmic drugs or other medications to treat your condition.

Directions for Use

  • Kofarest PD Syrup can be administered with or without food as directed by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Administer the prescribed dose to the child using the measuring cup/dosing syringe/dropper.
  • Shake well before use.

How Kofarest PD Syrup Works

This medicine uses three active components that work together to clear the lungs and ease breathing. First, ambroxol acts as a mucolytic agent. It works by breaking down the chemical bonds that hold thick mucus together, liquefying the phlegm so it becomes less sticky. Second, guaiphenesin is an expectorant. It increases the volume of fluid in the airways, lubricating the throat and windpipe to help your child easily cough up the thinned mucus. Third, terbutaline is a bronchodilator. It relaxes the tiny muscles surrounding the airways in the lungs, opening up the breathing tubes to relieve wheezing and shortness of breath.
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Alcohol

Not applicable

-

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Pregnancy

Not applicable

-

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Breast Feeding

Not applicable

-

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Driving

Not applicable

-

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Liver

Consult your doctor

If your child has a liver impairment, consult your doctor before using Kofarest PD Syrup .

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Kidney

Consult your doctor

If your child has kidney problems, consult your doctor before using Kofarest PD Syrup .

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Children

Safe if prescribed

Kofarest PD Syrup is safe for use in children if prescribed by the doctor. Your paediatrician will decide the dose of the medicine. Do not give more than the recommended dose to your child.

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Heart

Caution

Kofarest PD Syrup should be used cautiously in children with heart problems due to terbutaline’s potential cardiovascular effects. Always consult a pediatrician before use to ensure safety.

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Geriatrics

Not applicable

Kofarest PD Syrup is specifically for children use and is not meant for geriatric patients.

What if I have taken an overdose of Kofarest PD Syrup

If your child takes more than the prescribed dose, they may experience severe shakiness, a very fast heartbeat, or confusion. Seek emergency medical attention.

Diet & Lifestyle Advise

  • Keep your child well-hydrated by offering plenty of warm water, clear broths, or warm herbal teas to naturally thin mucus.
  • Use a cool-mist humidifier in your child's room to keep the air moist, which helps soothe dry, irritated breathing passages.
  • Keep your home free from tobacco smoke, strong perfumes, and dust, as these can irritate your child's airways and worsen coughing.
  • Elevate your child's head slightly with an extra pillow (if they are over one year old) to help drain mucus and reduce nighttime coughing.

Health Queries

My child has been suffering from cough and cold for the past one week. She is currently taking Solvin and Kofarest-PD syrup, but there has not been much improvement or quick relief. Should I wait for a few more days or consult the doctor again?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Cough and cold in children are commonly caused by viral infections and may sometimes take 1-2 weeks to improve completely, even when medicines are being used. Solvin and Kofarest-PD syrup may help reduce mucus, cough, and discomfort, but they do not always provide immediate relief because the body still needs time to recover from the infection. If your child is active, drinking fluids well, eating reasonably, and does not have breathing difficulty or high fever, you may continue supportive care for a few more days while closely monitoring the symptoms. Make sure your child gets enough rest, drinks plenty of warm fluids, avoids cold foods or drinks, and stays away from dust or smoke exposure. Steam inhalation, if suitable for the child's age and done safely, may also help loosen congestion. However, since the symptoms have already lasted for one week without much improvement, it would be a good idea to consult the doctor again if the cough becomes severe, the child develops fever, fast breathing, wheezing, vomiting, poor feeding, excessive sleepiness, ear pain, or if the cough continues beyond another few days. Sometimes, a repeated or persistent cough may be related to an allergy, sinus infection, throat irritation, or chest infection, which may need further evaluation. Avoid giving additional medicines or antibiotics on your own without medical advice. With proper care and timely review, most children recover well without complications.
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How Soon It Starts Working

The time required for Kofarest PD Syrup to start to work: Kofarest PD Syrup ideally shows its action within 30 minutes after administration. The time for which the effects of Kofarest PD Syrup last: The effect of Kofarest PD Syrup lasts for 4 to 8 hours.

What if you forget to take Kofarest PD Syrup

If you miss giving a dose, give it as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed dose and resume the regular schedule. Do not give a double dose to make up for a missed one.

Storage

•Store Kofarest PD Syrup oral liquid at room temperature, ideally below 30°C.•Keep the bottle tightly closed in its original packaging to protect the medicine from direct light and moisture.

Drug Warnings

  • Always check the appearance of the oral liquid before giving it; do not use it if you notice cloudiness, floating particles, or a change in colour.
  • Keep a close eye on your child during the first few days of treatment, as the active ingredients may cause temporary hyperactivity or mild hand tremors.
  • Do not use this medicine for a dry, hacking cough without mucus, as it is specifically designed to treat wet, congested coughs.
  • Avoid giving other over-the-counter cough or cold remedies at the same time to prevent accidental double-dosing of similar active medicines.
  • If your child's cough does not improve within 7 days, or if they develop a high fever, consult your doctor immediately.

Drug-Drug Interactions

verifiedApollotooltip
  • Beta-Blockers: Medicines used to treat heart conditions or high blood pressure, such as beta-blockers, may reduce the airway-relaxing effect of Kofarest PD Syrup , making it less effective in relieving breathing difficulties.
  • Diuretics (Water Pills): Taking Kofarest PD Syrup together with diuretics may further lower potassium levels in your blood, increasing the risk of muscle weakness, cramps, and irregular heartbeats. Your doctor may monitor your potassium levels during treatment.
  • Other Bronchodilators or Asthma Medicines: Using Kofarest PD Syrup with other bronchodilators or asthma medicines may increase the risk of side effects such as a rapid heart rate, palpitations, tremors, and nervousness. Your doctor may adjust your treatment or monitor you more closely.
Ambroxol + Guaifenesin + TerbutalineLabetalol
Severe
Ambroxol + Guaifenesin + TerbutalinePimozide
Severe

Drug-Drug Interactions

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Ambroxol + Guaifenesin + TerbutalineLabetalol
Severe
How does the drug interact with Kofarest PD Syrup 100 ml:
Co-administration of Labetalol and Kofarest PD Syrup 100 ml together can decrease the medical benefits of both medications.

How to manage the interaction:
Although taking Labetalol and Kofarest PD Syrup 100 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However contact your doctor if you experience chest pain, shortness of breath, cough, and wheezing. Do not discontinue any medications without a doctor's advice.
Ambroxol + Guaifenesin + TerbutalinePimozide
Severe
How does the drug interact with Kofarest PD Syrup 100 ml:
Using Kofarest PD Syrup 100 ml together with Pimozide can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking pimozide and Kofarest PD Syrup 100 ml together can cause an interaction, but it can be taken if prescribed by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
Ambroxol + Guaifenesin + TerbutalineArsenic trioxide
Severe
How does the drug interact with Kofarest PD Syrup 100 ml:
Using Kofarest PD Syrup 100 ml together with Arsenic trioxide can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Arsenic trioxide and Kofarest PD Syrup 100 ml can cause an interaction, but it can be taken if prescribed by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
Ambroxol + Guaifenesin + TerbutalineCarvedilol
Severe
How does the drug interact with Kofarest PD Syrup 100 ml:
Taking Carvedilol and Terbutaline may reduce the beneficial effects of both medications.

How to manage the interaction:
There may be a possibility of interaction between Terbutaline and Carvedilol, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
Ambroxol + Guaifenesin + TerbutalinePenbutolol
Severe
How does the drug interact with Kofarest PD Syrup 100 ml:
Since penbutolol and Kofarest PD Syrup 100 ml have opposing actions in the body, using them together may limit the positive effects of both drugs.

How to manage the interaction:
Taking Penbutolol and Kofarest PD Syrup 100 ml can cause an interaction, but it can be taken if prescribed by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
Ambroxol + Guaifenesin + TerbutalineCeritinib
Severe
How does the drug interact with Kofarest PD Syrup 100 ml:
Taking terbutaline with ceritinib can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Ceritinib and Terbutaline, you can take these medicines together if prescribed by your doctor. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
Ambroxol + Guaifenesin + TerbutalinePropranolol
Severe
How does the drug interact with Kofarest PD Syrup 100 ml:
Using propranolol together with Kofarest PD Syrup 100 ml may reduce the benefits of both medications since they have opposing effects on the body. In addition, propranolol can sometimes cause breathing problems.

How to manage the interaction:
Although taking Propranolol together with Kofarest PD Syrup 100 ml can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience shortness of breath, chest pain, or any other breathing issues contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Ambroxol + Guaifenesin + TerbutalineSotalol
Severe
How does the drug interact with Kofarest PD Syrup 100 ml:
Using sotalol together with Kofarest PD Syrup 100 ml may reduce the benefits of both medications since they have opposing effects on the body.

How to manage the interaction:
Taking Sotalol and Kofarest PD Syrup 100 ml together can result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience chest pain, shortness of breath cough, and wheezing. Do not stop using any medications without a doctor's advice.
Ambroxol + Guaifenesin + TerbutalineZiprasidone
Severe
How does the drug interact with Kofarest PD Syrup 100 ml:
Taking Kofarest PD Syrup 100 ml with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ziprasidone with Kofarest PD Syrup 100 ml can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
Ambroxol + Guaifenesin + TerbutalinePhenelzine
Severe
How does the drug interact with Kofarest PD Syrup 100 ml:
Using Kofarest PD Syrup 100 ml together with Phenelzine can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Phenelzine and Kofarest PD Syrup 100 ml together can cause an interaction, but it can be taken if prescribed by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Caffeine: Limit excessive intake of caffeine-containing beverages, such as coffee, tea, energy drinks, and certain soft drinks, as they may worsen side effects like nervousness, tremors, and a rapid heart rate while taking Kofarest PD Syrup .
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[EXPECTORANT AND COUGH PRODUCTS]

FAQs

Kofarest PD Syrup is used to treat Cough.
Kofarest PD Syrup contains Ambroxol, Guaiphenesin and Terbutaline. Ambroxol works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose and thus helps to cough out phlegm easily. Guaiphenesin increases the fluid volume in the airways and helps remove it from the airways. Terbutaline relaxes muscles and widens the airways. Thereby it makes breathing easier.
If your child feels better, please consult your paediatrician before you stop giving Kofarest PD Syrup to your child.
It is advised not to miss any dose of Kofarest PD Syrup . However, if you forget to give the dose to your child, give it as soon as you remember unless it is time for the next dose. Do not double the dose.
No, this medicine is specifically designed for wet coughs with mucus. Giving it for a dry cough will not be effective and may cause unnecessary side effects. Talk to your doctor for advice on dry coughs.
Yes, some children may experience mild shakiness, restlessness, or a slightly faster heart rate. This is a common response to the airway-relaxing ingredient and usually goes away as the medicine wears off. Talk to your doctor if you are concerned.
You can give this medicine with or without food. If your child has a sensitive stomach, giving it after a light meal can help prevent mild nausea or stomach upset.
If your child vomits immediately (within 15 minutes) after taking the medicine, consult your doctor or pharmacist to ask if you should repeat the dose. Do not give an extra dose without professional advice.
Avoid combining this medicine with other cough or cold remedies unless specifically advised by your doctor, as this can lead to accidental overdosing or harmful drug interactions.
This medicine can help relieve asthmatic coughs by widening the airways, but it should only be used under the strict supervision of a doctor who knows your child's complete medical history.
Generally, most oral liquids should not be used longer than 4 weeks to 6 weeks after opening, even if they are within their expiration date. Check the product packaging or talk to your pharmacist for specific advice on storage.

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Country of origin

INDIA

Manufacturer/Marketer address

CENTAUR HOUSE, Near Grand Hyatt, Vakola ,Santacruz ? East, Mumbai ? 400 055, India.
Other Info - KOF0149
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