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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Ivtrim Inj 5Ml is a combination medicine used in the treatment of bacterial infections of the urinary tract, respiratory tract, ear, lungs, skin, brain and toxoplasmosis. It contains trimethoprim and sulfamethoxazole which stops the production of tetrahydrofolic acid and dihydrofolic acid and thereby stops the growth of the infection-causing bacteria. Sometimes, your may experience common side effects like headache, nausea, diarrhoea, and skin rashes.
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Manufacturer/Marketer :

Converge Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Ivtrim Inj 5Ml

Ivtrim Inj 5Ml belongs to the group of medicines called ‘antibiotics’ used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Ivtrim Inj 5Ml does not work against infections caused by the virus, including cold and flu. 

Ivtrim Inj 5Ml is a combination of two antibiotics, namely: Trimethoprim and Sulfamethoxazole. Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids in the bacterial cell, which is necessary for the survival of the bacteria. By inhibiting these, Ivtrim Inj 5Ml stops the growth of bacteria and kills them. Thereby, it helps to treat bacterial infections.

Ivtrim Inj 5Ml will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side effects such as high levels of potassium in the blood, palpitations (abnormal heartbeats), thrush or candidiasis (fungal infection), headache, nausea, diarrhoea, and skin rashes. Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before starting Ivtrim Inj 5Ml, please inform your doctor if you have any allergy (against any antibiotic), severe kidney or liver problems, porphyria (blood disorder), or blood problems which may cause bleeding or bruising. Inform your doctor if you are pregnant or breastfeeding before receiving this injection. Ivtrim Inj 5Ml is not recommended for infants below 6 weeks. Keep your doctor informed about your medical history and your ongoing medications to rule out any side effects/interactions.

Uses of Ivtrim Inj 5Ml

Treatment of Bacterial infections

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Ivtrim Inj 5Ml will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Ivtrim Inj 5Ml belongs to the group of medicines called ‘antibiotics’ used to treat various bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Ivtrim Inj 5Ml is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids in the bacterial cell, which is necessary for the survival of the bacteria. By inhibiting these, Ivtrim Inj 5Ml kills the bacteria and stops their growth. Thereby, it helps to treat bacterial infections. Ivtrim Inj 5Ml is a broad-spectrum antibiotic which is active against a wide range of gram-positive and gram-negative bacteria.

How Ivtrim Inj 5Ml Works

Ivtrim Inj 5Ml is a combination of two antibiotics, namely: Trimethoprim and Sulfamethoxazole. Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids in the bacterial cell, which is necessary for the survival of the bacteria. By inhibiting these, Ivtrim Inj 5Ml stops the growth of bacteria and kills them. Thereby, it helps to treat bacterial infections.

Storage

• Store in a cool and dry place away from sunlight.• Keep Ivtrim Inj 5Ml out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Ivtrim Inj 5Ml

Ivtrim Inj 5Ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Overdose of Ivtrim Inj 5Ml may cause nausea/vomiting, headache, mental depression, confusion, thrombocytopenia, uremia, and loss of appetite. Your doctor will initiate necessary measures when an overdose is suspected.

Drug Warnings

Do not take Ivtrim Inj 5Ml if you are allergic to any of its contents; if you have severe liver or kidney problems, thrombocytopenia (low levels of platelets in the blood), or porphyria (a rare blood problem). Consult your doctor immediately if you experience skin rash or prolonged, significant diarrhoea with abdominal pain. Talk to your doctor before taking Ivtrim Inj 5Ml if you have severe allergies, asthma, ulcers, blood disorders, thyroid dysfunction, diabetes, are elderly, underweight or malnourished; if you have a folic acid deficiency, glucose-6-phosphate dehydrogenase deficiency, or high levels of potassium in the blood. Consult your doctor if you are pregnant or breastfeeding. 

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical

Drug-Drug Interactions

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TrimethoprimBCG vaccine
Critical
How does the drug interact with Ivtrim Inj 5Ml:
Taking Ivtrim Inj 5Ml with BCG vaccine can reduce the effectiveness of the BCG vaccine

How to manage the interaction:
Although there is an interaction between Ivtrim Inj 5Ml and BCG vaccine is not recommended, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ivtrim Inj 5Ml:
Taking Ramipril with Ivtrim Inj 5Ml can increase the potassium levels in the blood, increasing the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between ramipril and Ivtrim Inj 5Ml, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience weakness, confusion, numbness or tingling, and uneven heartbeats. Do not stop taking any medication without consulting your doctor.
TrimethoprimPotassium gluconate
Severe
How does the drug interact with Ivtrim Inj 5Ml:
Taking potassium gluconate with Ivtrim Inj 5Ml can increase the risk of high potassium levels in the blood.

How to manage the interaction:
Although there is a possible interaction between Ivtrim Inj 5Ml and Potassium gluconate, you can take these medicines together if prescribed by your doctor. However, if you are feeling sick, feeling weak, confused, or having a weak or irregular heartbeat contact your doctor immediately. Do not stop using any medications without talking to your doctor.
TrimethoprimProcaine
Severe
How does the drug interact with Ivtrim Inj 5Ml:
Co-administration of Ivtrim Inj 5Ml with procaine may increase the risk of blood disorders.

How to manage the interaction:
Taking Ivtrim Inj 5Ml with Procaine together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms like gray skin, feeling sick, headache, dizziness, tiredness, trouble breathing, fast heartbeat, or feeling anxious or confused, contact your doctor right away. Do not stop using any medications without talking to your doctor.
How does the drug interact with Ivtrim Inj 5Ml:
Taking Ivtrim Inj 5Ml with telmisartan may increase potassium levels in the blood.

How to manage the interaction:
Although there is an interaction between telmisartan and Ivtrim Inj 5Ml, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, and a weak pulse. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Ivtrim Inj 5Ml:
Using Ivtrim Inj 5Ml together with valsartan may increase potassium levels in the blood.

How to manage the interaction:
Although taking Ivtrim Inj 5Ml together with Valsartan may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Ivtrim Inj 5Ml:
Taking Lidocaine with Ivtrim Inj 5Ml may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Ivtrim Inj 5Ml with Lidocaine can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience, gray skin color, feeling sick, having a headache, feeling dizzy or lightheaded, feeling tired, having trouble breathing, a fast or irregular heartbeat, feeling anxious or confused, contact your doctor right away. Do not stop using any medications without talking to your doctor.
How does the drug interact with Ivtrim Inj 5Ml:
Taking Potassium chloride with Ivtrim Inj 5Ml may increase potassium levels in the blood. High potassium levels can cause hyperkalemia (a high level of the electrolyte potassium in the blood.).

How to manage the interaction:
Although there is a possible interaction between Ivtrim Inj 5Ml and Potassium chloride, you can take these medicines together if prescribed by a doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Ivtrim Inj 5Ml:
Coadministration of Azilsartan medoxomil with Ivtrim Inj 5Ml may increase potassium levels in the blood.

How to manage the interaction:
Although there is an interaction between azilsartan medoxomil and Ivtrim Inj 5Ml, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, weakness, or tingling in your hands and feet. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Ivtrim Inj 5Ml:
Enalapril combined with Ivtrim Inj 5Ml can cause hyperkalemia by elevating blood potassium levels. In severe cases, hyperkalemia can induce muscle paralysis, renal damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of renal or cardiovascular disease.

How to manage the interaction:
Although taking Enalapril together with Ivtrim Inj 5Ml may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

 

Habit Forming

No

Therapeutic Class

ANTIBIOTIC COMBINATION
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Alcohol

Caution

Avoid alcohol consumption while taking Ivtrim Inj 5Ml to prevent unpleasant side effects.

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Pregnancy

Caution

Please inform your doctor before taking Ivtrim Inj 5Ml if you are pregnant. Ivtrim Inj 5Ml may cause fetal harm. Your doctor will prescribe Ivtrim Inj 5Ml only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid breastfeeding whilst on treatment with Ivtrim Inj 5Ml as it may cause bilirubin displacement and kernicterus (brain damage resulting from high levels of bilirubin in the blood). Please consult your doctor if you have any concerns.

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Driving

Caution

It is unknown whether Ivtrim Inj 5Ml affects your ability to drive and operate machinery. Drive only if you are physically stable and mentally focused.

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Liver

Caution

Please inform your doctor before taking Ivtrim Inj 5Ml if you have liver impairment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative if necessary based on your condition.

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Kidney

Caution

Please inform your doctor before taking Ivtrim Inj 5Ml if you have kidney impairment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative if necessary based on your condition.

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Children

Caution

Ivtrim Inj 5Ml is not recommended for infants below 6 weeks.

Have a query?

FAQs

Ivtrim Inj 5Ml belongs to the group of medicines called antibiotics used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma).

Ivtrim Inj 5Ml is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. By inhibiting these, Ivtrim Inj 5Ml kills the bacteria and stops their growth. Thus, it helps to treat bacterial infections.

Ivtrim Inj 5Ml causes thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.

Diarrhoea might be a side-effect of Ivtrim Inj 5Ml. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, inform your doctor. Do not take anti-diarrheal medicine on your own.

Ivtrim Inj 5Ml may affect certain laboratory test results. Inform the lab technician that you are taking Ivtrim Inj 5Ml.

Ivtrim Inj 5Ml may cause high levels of potassium in the blood, which could lead to abnormal heartbeats (palpitations). Regular monitoring of potassium levels and heart rate is advised while taking Ivtrim Inj 5Ml.

Country of origin

INDIA

Manufacturer/Marketer address

7-2-1813,/5/A/1, Vasavi'S Central Court, Unit-Ii , 3Rd Floor, Czech Colony, Sanath Nagar, Hyderabad - 500018., Telangana State, India.
Other Info - IVT0001

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